ATE201199T1 - Benzo(g)chinolinderivate - Google Patents

Benzo(g)chinolinderivate

Info

Publication number: ATE201199T1
Authority: AT; Austria
Prior art keywords: benzo; quinoline derivatives; quinoline; derivatives
Prior art date: 1995-07-07

Application number

AT96925672T

Other languages

English (en)

Inventor

Peter Neumann

Paul Pfaeffli

Max Peter Seiler

Robert Swoboda

Original Assignee

Novartis Erfind Verwalt Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-07

Filing date

1996-07-05

Publication date

2001-06-15

1995-07-07 Priority claimed from GBGB9513880.6A external-priority patent/GB9513880D0/en

1996-02-26 Priority claimed from GBGB9603988.8A external-priority patent/GB9603988D0/en

1996-07-05 Application filed by Novartis Erfind Verwalt Gmbh filed Critical Novartis Erfind Verwalt Gmbh

2001-06-15 Application granted granted Critical

2001-06-15 Publication of ATE201199T1 publication Critical patent/ATE201199T1/de

Links

RFQDDXWZZVRLKO-UHFFFAOYSA-N benzo[g]quinoline Chemical class N1=CC=CC2=CC3=CC=CC=C3C=C21 RFQDDXWZZVRLKO-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/08—Aza-anthracenes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AT96925672T 1995-07-07 1996-07-05 Benzo(g)chinolinderivate ATE201199T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9513880.6A GB9513880D0 (en)	1995-07-07	1995-07-07	Organic compounds
GBGB9603988.8A GB9603988D0 (en)	1996-02-26	1996-02-26	Organic compounds
PCT/EP1996/002969 WO1997003054A1 (en)	1995-07-07	1996-07-05	BENZO[g]QUINOLINE DERIVATIVES

Publications (1)

Publication Number	Publication Date
ATE201199T1 true ATE201199T1 (de)	2001-06-15

Family

ID=26307342

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96925672T ATE201199T1 (de)	1995-07-07	1996-07-05	Benzo(g)chinolinderivate

Country Status (28)

Country	Link
US (1)	US5885988A (de)
EP (1)	EP0839136B1 (de)
JP (1)	JPH11509197A (de)
KR (1)	KR19990028757A (de)
CN (1)	CN1193964A (de)
AR (1)	AR004672A1 (de)
AT (1)	ATE201199T1 (de)
AU (1)	AU703325B2 (de)
BR (1)	BR9609326A (de)
CA (1)	CA2224436A1 (de)
CO (1)	CO4750662A1 (de)
CZ (1)	CZ1698A3 (de)
DE (1)	DE69612852T2 (de)
DK (1)	DK0839136T3 (de)
ES (1)	ES2158327T3 (de)
GR (1)	GR3036346T3 (de)
HU (1)	HUP9802937A3 (de)
IL (1)	IL122854A (de)
NO (1)	NO310070B1 (de)
NZ (1)	NZ313606A (de)
PE (1)	PE1998A1 (de)
PL (1)	PL324106A1 (de)
PT (1)	PT839136E (de)
RU (1)	RU2158738C2 (de)
SK (1)	SK1798A3 (de)
TR (1)	TR199800011T1 (de)
TW (1)	TW357143B (de)
WO (1)	WO1997003054A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9711043D0 (en)	1997-05-29	1997-07-23	Ciba Geigy Ag	Organic compounds
EP1070054A1 (de) *	1998-04-08	2001-01-24	Takeda Chemical Industries, Ltd.	Aminverbindungen, ihre herstellung und ihre verwendung als somatostatin rezeptor antagonisten oder agonisten
CA2246791A1 (en) *	1998-09-01	2000-03-01	Alison Buchan	Treatment of endothelium with somatostatin analogues
RU2221785C2 (ru) *	1998-09-22	2004-01-20	Яманоути Фармасьютикал Ко., Лтд.	Гетероциклическое производное, фармацевтическая композиция, его содержащая, и промежуточный продукт
US6673799B1 (en) *	1998-09-22	2004-01-06	Yamanouchi Pharmaceutical Co. Ltd.	Cyanophenyl derivative
GB9902938D0 (en) *	1999-02-10	1999-03-31	Novartis Ag	Organic compounds
PE20030240A1 (es)	2001-07-09	2003-04-16	Novartis Ag	DERIVADOS DE BENZO [g] QUINOLINA
FI20031454A0 (fi)	2003-10-06	2003-10-06	Juvantia Pharma Ltd Oy	Selektiivisiä somatostatiinireseptori 1 ja/tai 4 -agonisteja ja -antagonisteja
KR100594234B1 (ko)	2003-12-05	2006-06-30	삼성전자주식회사	편광 현상을 이용하여 해상도를 향상시킬 수 있는 포토마스크 및 그 제조방법
AR051026A1 (es)	2004-09-20	2006-12-13	Xenon Pharmaceuticals Inc	Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
WO2006034341A2 (en)	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
CA2580855A1 (en)	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
TW200626138A (en)	2004-09-20	2006-08-01	Xenon Pharmaceuticals Inc	Heterocyclic derivatives and their use as therapeutic agents
MX2007003327A (es)	2004-09-20	2007-06-05	Xenon Pharmaceuticals Inc	Derivados heterociclicos, y su uso como mediadores de estearoil-coa desaturasa.
BRPI0515482A (pt)	2004-09-20	2008-07-22	Xenon Pharmaceuticals Inc	derivados heterocìclicos e seus usos como agentes terapêuticos
US8071603B2 (en)	2004-09-20	2011-12-06	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
US8541457B2 (en)	2005-06-03	2013-09-24	Xenon Pharmaceuticals Inc.	Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors
TWI404702B (zh) *	2007-08-31	2013-08-11	Lundbeck & Co As H	兒茶酚胺衍生物和其前藥
US8067410B2 (en)	2008-06-27	2011-11-29	H. Lundbeck A/S	Phenolic and catecholic amines and prodrugs thereof
EP3634406B1 (de)	2017-05-12	2023-09-06	Board of Trustees of The Southern Illinois University on behalf of Southern Illinois University Edwardsville	3,4,5-trisubstituierte-1,2,4-triazole und 3,4,5-trisubstituierte-3-thio-1,2,4-triazole und verwendungen davon
US11912687B2 (en)	2017-05-12	2024-02-27	Board of Trustees of the Southern Illinois University	3,4,5-trisubstituted-1,2,4-triazoles and 3,4,5-trisubstituted-3-thio-1,2,4-triazoles and uses thereof
AR113908A1 (es)	2017-11-24	2020-06-24	H Lundbeck As	Profármacos de catecolamina para uso en el tratamiento de la enfermedad de parkinson
US11130775B2 (en)	2019-05-20	2021-09-28	H. Lundbeck A/S	Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11104697B2 (en)	2019-05-20	2021-08-31	H. Lundbeck A/S	Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en)	2019-05-20	2021-11-09	H. Lundbeck A/S	Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
US11111263B2 (en)	2019-05-20	2021-09-07	H. Lundbeck A/S	Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
CN113677675B (zh)	2019-05-21	2024-07-26	H.隆德贝克有限公司	用于治疗帕金森病的新儿茶酚胺前药
CN113727979B (zh)	2019-05-21	2024-09-20	H.隆德贝克有限公司	用于治疗帕金森病的新儿茶酚胺前药
EP3972600B1 (de)	2019-05-21	2026-02-18	H. Lundbeck A/S	Catecholamin-carbamat-prodrugs zur verwendung bei der behandlung von morbus parkinson
US12391650B2 (en)	2019-05-21	2025-08-19	H. Lundbeck A/S	Catecholamine prodrugs for use in the treatment of Parkinson's disease
JP7099717B2 (ja)	2019-09-30	2022-07-12	株式会社理研バイオ	ソマトスタチン受容体

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH630902A5 (en) *	1977-01-24	1982-07-15	Sandoz Ag	Process for preparing novel derivatives of 1,2,3,4,4a,10b-hexahydrobenzo(f)isoquinoline.
LU88619I2 (fr) *	1981-10-16	1995-07-10	Sandoz Ag	QUINAGOLIDE, éventuellement sous forme de sel, par exemple du chlorhydrate
SU1109393A1 (ru) *	1983-04-28	1984-08-23	Ордена Трудового Красного Знамени Институт Физики Ан Бсср	Способ получени 9-диэтиламинобензо/ @ /феноксазинона-5 или его производных
NL194166C (nl) *	1984-06-12	2001-08-03	Novartis Ag	Naftoxazinen en bereiding en toepassing daarvan. Hexahydronaft[2,3-b]-1,4-oxazinen en farmaceutische preparaten die ze bevatten.
NL8702680A (nl) *	1986-11-21	1988-06-16	Sandoz Ag	Nieuwe benzogchinolinen en werkwijzen voor het bereiden en toepassen van deze verbindingen.
WO1993024471A1 (en) *	1992-06-02	1993-12-09	Whitby Research, Inc.	Substituted naphthoxazines useful as dopaminergics
AU6413594A (en) *	1993-03-24	1994-10-11	Merck & Co., Inc.	Substituted 3-phenanthridinone derivatives as 5alpha-reductase inhibitors
DE4329776A1 (de) *	1993-09-03	1995-03-09	Sandoz Ag	Naphthoxazine, ihre Herstellung und Verwendung

1996
- 1996-06-12 TW TW085107047A patent/TW357143B/zh active
- 1996-07-05 EP EP96925672A patent/EP0839136B1/de not_active Expired - Lifetime
- 1996-07-05 NZ NZ313606A patent/NZ313606A/xx unknown
- 1996-07-05 HU HU9802937A patent/HUP9802937A3/hu unknown
- 1996-07-05 CA CA002224436A patent/CA2224436A1/en not_active Abandoned
- 1996-07-05 TR TR1998/00011T patent/TR199800011T1/xx unknown
- 1996-07-05 US US08/983,535 patent/US5885988A/en not_active Expired - Fee Related
- 1996-07-05 WO PCT/EP1996/002969 patent/WO1997003054A1/en not_active Ceased
- 1996-07-05 CZ CZ9816A patent/CZ1698A3/cs unknown
- 1996-07-05 PE PE1996000517A patent/PE1998A1/es not_active Application Discontinuation
- 1996-07-05 SK SK17-98A patent/SK1798A3/sk unknown
- 1996-07-05 KR KR1019980700056A patent/KR19990028757A/ko not_active Ceased
- 1996-07-05 PL PL96324106A patent/PL324106A1/xx unknown
- 1996-07-05 AR ARP960103468A patent/AR004672A1/es unknown
- 1996-07-05 CO CO96035363A patent/CO4750662A1/es unknown
- 1996-07-05 PT PT96925672T patent/PT839136E/pt unknown
- 1996-07-05 ES ES96925672T patent/ES2158327T3/es not_active Expired - Lifetime
- 1996-07-05 RU RU98102128/04A patent/RU2158738C2/ru active
- 1996-07-05 AT AT96925672T patent/ATE201199T1/de not_active IP Right Cessation
- 1996-07-05 BR BR9609326A patent/BR9609326A/pt active Search and Examination
- 1996-07-05 AU AU66120/96A patent/AU703325B2/en not_active Ceased
- 1996-07-05 CN CN96196551A patent/CN1193964A/zh active Pending
- 1996-07-05 IL IL12285496A patent/IL122854A/xx not_active IP Right Cessation
- 1996-07-05 DE DE69612852T patent/DE69612852T2/de not_active Expired - Fee Related
- 1996-07-05 DK DK96925672T patent/DK0839136T3/da active
- 1996-07-05 JP JP9505489A patent/JPH11509197A/ja active Pending
1998
- 1998-01-05 NO NO980043A patent/NO310070B1/no not_active IP Right Cessation
2001
- 2001-08-07 GR GR20010401198T patent/GR3036346T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
TW357143B (en)	1999-05-01
DK0839136T3 (da)	2001-08-06
IL122854A (en)	2000-12-06
GR3036346T3 (en)	2001-11-30
EP0839136A1 (de)	1998-05-06
HUP9802937A3 (en)	2002-10-28
AR004672A1 (es)	1999-03-10
NO980043L (no)	1998-01-05
ES2158327T3 (es)	2001-09-01
AU6612096A (en)	1997-02-10
NO980043D0 (no)	1998-01-05
CA2224436A1 (en)	1997-01-30
CZ1698A3 (cs)	1998-04-15
BR9609326A (pt)	1999-05-25
AU703325B2 (en)	1999-03-25
DE69612852T2 (de)	2001-10-04
PT839136E (pt)	2001-09-28
JPH11509197A (ja)	1999-08-17
EP0839136B1 (de)	2001-05-16
RU2158738C2 (ru)	2000-11-10
HUP9802937A2 (hu)	1999-10-28
IL122854A0 (en)	1998-08-16
MX9710530A (es)	1998-03-31
NZ313606A (en)	1999-07-29
NO310070B1 (no)	2001-05-14
US5885988A (en)	1999-03-23
TR199800011T1 (xx)	1998-04-21
WO1997003054A1 (en)	1997-01-30
CO4750662A1 (es)	1999-03-31
KR19990028757A (ko)	1999-04-15
CN1193964A (zh)	1998-09-23
PL324106A1 (en)	1998-05-11
PE1998A1 (es)	1998-02-14
DE69612852D1 (de)	2001-06-21
SK1798A3 (en)	1998-06-03

Legal Events

Date	Code	Title	Description
2001-09-15	UEP	Publication of translation of european patent specification
2003-04-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE201199T1 (de)	2001-06-15	Benzo(g)chinolinderivate
ATE289994T1 (de)	2005-03-15	Chinolin-derivate
DE69611361D1 (de)	2001-02-01	Chinazolin-derivate
DE69522717D1 (de)	2001-10-18	Chinazolinderivate
NO974103D0 (no)	1997-09-05	Arylsulfonylaminohydroksamsyre-derivater
DE69610698D1 (de)	2000-11-23	Chinazolin-derivate
ATE199150T1 (de)	2001-02-15	Diphenylmethylenpiperidin-derivate
NO964667D0 (no)	1996-11-05	Purin-6-on-derivater
DE69601527D1 (de)	1999-03-25	Pyrrolylbenzimidazol-Derivate
ATA100695A (de)	1998-03-15	Prothrombin-derivate
DE69628200D1 (de)	2003-06-18	Diarylalkenylamin-derivate
DE69627830D1 (de)	2003-06-05	Pyrazol-derivate
DK0723963T3 (da)	2001-09-24	4-Amino-benzoylguanidin-derivater
DE69601611D1 (de)	1999-04-08	Chromanderivate
DE59610106D1 (de)	2003-03-13	Fluorbenzylether-Derivate
BR9710218A (pt)	1999-08-10	Derivados de benzo(g)quinolina
ATE225347T1 (de)	2002-10-15	Aza-anthracyclinone-derivate
ATE202088T1 (de)	2001-06-15	4-mercapto-benzoylguanidin-derivate
DE69620514D1 (de)	2002-05-16	5-aminoflavon-derivate
ATA45796A (de)	1999-09-15	Lysin-prolin-derivate
SI0839136T1 (en)	2001-10-31	BENZO(g)QUINOLINE DERIVATIVES
ITMI950495A0 (it)	1995-03-14	Derivati chinolinici
ITMI950494A0 (it)	1995-03-14	Derivati chinolinici
ZA965748B (en)	1998-01-05	Benzo(g)quinoline derivatives.