ATE202784T1 - Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen - Google Patents

Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number: ATE202784T1
Authority: AT; Austria
Prior art keywords: alkyl; dialkylamino; alkylamino; halogen; ether
Prior art date: 1994-08-02

Application number

AT95926996T

Other languages

English (en)

Inventor

Pascal Anger

Jean-Claude Barriere

Bertrand Bonnavaud

Patrick Lefevre

Jean-Marc Paris

Denis Thibaut

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-08-02

Filing date

1995-07-31

Publication date

2001-07-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9465984&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE202784(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-07-31 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2001-07-15 Application granted granted Critical

2001-07-15 Publication of ATE202784T1 publication Critical patent/ATE202784T1/de

Links

108010034396 Streptogramins Proteins 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
229940041030 streptogramins Drugs 0.000 title 1
125000004663 dialkyl amino group Chemical group 0.000 abstract 5
125000003282 alkyl amino group Chemical group 0.000 abstract 4
229910052736 halogen Inorganic materials 0.000 abstract 4
125000005843 halogen group Chemical group 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
125000004414 alkyl thio group Chemical group 0.000 abstract 3
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
125000003342 alkenyl group Chemical group 0.000 abstract 1
-1 alkylthiomethyl Chemical group 0.000 abstract 1
MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000004981 cycloalkylmethyl group Chemical group 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06182—Dipeptides with the first amino acid being heterocyclic and Pristinamycin II; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

AT95926996T 1994-08-02 1995-07-31 Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen ATE202784T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9409564A FR2723373B1 (fr)	1994-08-02	1994-08-02	Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent
PCT/FR1995/001026 WO1996004298A1 (fr)	1994-08-02	1995-07-31	Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent

Publications (1)

Publication Number	Publication Date
ATE202784T1 true ATE202784T1 (de)	2001-07-15

Family

ID=9465984

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95926996T ATE202784T1 (de)	1994-08-02	1995-07-31	Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen

Country Status (13)

Country	Link
US (1)	US6384014B1 (de)
EP (1)	EP0773956B1 (de)
JP (1)	JPH10503511A (de)
AT (1)	ATE202784T1 (de)
AU (1)	AU3117495A (de)
CA (1)	CA2196450A1 (de)
DE (1)	DE69521615T2 (de)
DK (1)	DK0773956T3 (de)
ES (1)	ES2160171T3 (de)
FR (1)	FR2723373B1 (de)
GR (1)	GR3036173T3 (de)
PT (1)	PT773956E (de)
WO (1)	WO1996004298A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU1624999A (en) *	1997-12-24	1999-07-19	Teresa J. Ingram	Compositions comprising equisetum and symphytum and methods for the treatment of symptoms associated with mycoplasma infection
FR2775288B1 (fr) *	1998-02-26	2000-03-31	Rhone Poulenc Rorer Sa	Derives de streptogramines, leur preparation et les compositons qui les contiennent
FR2796950B1 (fr) *	1999-07-27	2001-09-21	Aventis Pharma Sa	Derives de streptogramines, leur preparation et les compositions qui les contiennent
DK1204676T3 (da) *	1999-07-27	2003-12-01	Aventis Pharma Sa	Streptograminderivater, deres fremstilling samt præparater indeholdende disse derivater
CA2482991A1 (en)	2002-04-19	2003-10-30	Cellular Genomics, Inc.	Imidazo[1,2-a]pyrazin-8-ylamines method of making and method of use thereof
WO2004022562A1 (en)	2002-09-09	2004-03-18	Cellular Genomics, Inc.	6-ARYL-IMIDAZO[1,2-a]PYRAZIN-8-YLAMINES, METHOD OF MAKING, AND METHOD OF USE THEREOF
US7160885B2 (en)	2003-02-10	2007-01-09	Cgi Pharmaceuticals, Inc.	Certain 6, 8-(heteroaryl or aryl) disubstituted imidazo[1,2-a]pyrazines as modulators of Hsp90 complex activity
WO2005014599A1 (en)	2003-06-04	2005-02-17	Cellular Genomics, Inc.	Imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of bruton’s tyrosine kinase by such compounds
WO2005005429A1 (en)	2003-06-30	2005-01-20	Cellular Genomics, Inc.	Certain heterocyclic substituted imidazo[1,2-a]pyrazin-8-ylamines and methods of inhibition of bruton’s tyrosine kinase by such compounds
US7259164B2 (en)	2003-08-11	2007-08-21	Cgi Pharmaceuticals, Inc.	Certain substituted imidazo[1,2-a]pyrazines, as modulators of kinase activity
WO2007024294A2 (en)	2005-05-03	2007-03-01	Cgi Pharmaceuticals, Inc.	Certain substituted ureas, as modulators of kinase activity
US7776535B2 (en)	2006-02-06	2010-08-17	Franklin And Marshall College	Site-specific incorporation of fluorinated amino acids into proteins
NZ587039A (en)	2008-02-13	2013-01-25	Gilead Connecticut Inc	6-aryl-imidazo[1, 2-a]pyrazine derivatives, method of making, and method of use thereof
US8450321B2 (en)	2008-12-08	2013-05-28	Gilead Connecticut, Inc.	6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
KR101743784B1 (ko)	2008-12-08	2017-06-05	질레드 코네티컷 인코포레이티드	이미다조피라진 ｓｙｋ 억제제
KR101745732B1 (ko)	2008-12-08	2017-06-12	질레드 코네티컷 인코포레이티드	이미다조피라진 ｓｙｋ 억제제
ES2530449T3 (es)	2010-03-11	2015-03-02	Gilead Connecticut Inc	Inhibidores de Syk de imidazopiridinas
EA029281B1 (ru)	2013-07-30	2018-03-30	Джилид Коннектикут, Инк.	Полиморф ингибиторов syk
SG11201600378SA (en)	2013-07-30	2016-02-26	Gilead Connecticut Inc	Formulation of syk inhibitors
US9687492B2 (en)	2013-12-04	2017-06-27	Gilead Sciences, Inc.	Methods for treating cancers
TWI735853B (zh)	2013-12-23	2021-08-11	美商克洛諾斯生技有限公司	脾酪胺酸激酶抑制劑
US9290505B2 (en)	2013-12-23	2016-03-22	Gilead Sciences, Inc.	Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
CA2955180A1 (en)	2014-07-14	2016-01-21	Gilead Sciences, Inc.	Combinations comprising entospletinib and a vinca-alkaloid for treating cancers
CN115028640A (zh)	2017-08-25	2022-09-09	吉利德科学公司	Syk抑制剂的多晶型物
WO2020172431A1 (en)	2019-02-22	2020-08-27	Gilead Sciences, Inc.	Solid forms of condensed pyrazines as syk inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2549063B1 (fr)	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2549062B1 (fr)	1983-07-13	1985-10-25	Rhone Poulenc Sante	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2576022B1 (fr)	1985-01-11	1987-09-11	Rhone Poulenc Sante	Nouveaux derives de la pristinamycine ii b, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2599036B1 (fr)	1986-05-22	1988-09-09	Rhone Poulenc Sante	Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2619008B1 (fr)	1987-08-03	1990-06-29	Cird	Utilisation de synergistines dans des compositions pharmaceutiques ou cosmetiques anti-acneiques
FR2674539B1 (fr) *	1991-03-28	1993-05-21	Rhone Poulenc Rorer Sa	Procede de preparation enzymatique de macrolactone.
FR2696189B1 (fr)	1992-09-25	1994-11-10	Rhone Poulenc Rorer Sa	Polypeptides impliqués dans la biosynthèse des streptogramines, séquences nucléotidiques codant pour ces polypeptides et leur utilisation.
IL121821A (en) *	1993-02-17	2000-02-17	Rhone Poulenc Rorer Sa	Process for purifying a group A minority component of streptogramin some such purified components and their uses
FR2701709B1 (fr)	1993-02-17	1995-04-07	Rhone Poulenc Rorer Sa	Forme purifiée de streptograminés, sa préparation et les compositions pharmaceutiques qui la contiennent.

1994
- 1994-08-02 FR FR9409564A patent/FR2723373B1/fr not_active Expired - Fee Related
1995
- 1995-07-31 ES ES95926996T patent/ES2160171T3/es not_active Expired - Lifetime
- 1995-07-31 EP EP95926996A patent/EP0773956B1/de not_active Expired - Lifetime
- 1995-07-31 CA CA002196450A patent/CA2196450A1/fr not_active Abandoned
- 1995-07-31 DK DK95926996T patent/DK0773956T3/da active
- 1995-07-31 JP JP8506255A patent/JPH10503511A/ja not_active Ceased
- 1995-07-31 AT AT95926996T patent/ATE202784T1/de not_active IP Right Cessation
- 1995-07-31 DE DE69521615T patent/DE69521615T2/de not_active Expired - Fee Related
- 1995-07-31 PT PT95926996T patent/PT773956E/pt unknown
- 1995-07-31 WO PCT/FR1995/001026 patent/WO1996004298A1/fr not_active Ceased
- 1995-07-31 AU AU31174/95A patent/AU3117495A/en not_active Abandoned
2000
- 2000-03-10 US US09/522,949 patent/US6384014B1/en not_active Expired - Fee Related
2001
- 2001-07-05 GR GR20010400545T patent/GR3036173T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2160171T3 (es)	2001-11-01
FR2723373B1 (fr)	1996-09-13
CA2196450A1 (fr)	1996-02-15
EP0773956B1 (de)	2001-07-04
AU3117495A (en)	1996-03-04
GR3036173T3 (en)	2001-10-31
US6384014B1 (en)	2002-05-07
JPH10503511A (ja)	1998-03-31
DK0773956T3 (da)	2001-09-24
DE69521615T2 (de)	2002-05-08
WO1996004298A1 (fr)	1996-02-15
PT773956E (pt)	2001-11-30
DE69521615D1 (de)	2001-08-09
EP0773956A1 (de)	1997-05-21
FR2723373A1 (fr)	1996-02-09

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Legal Events

Date	Code	Title	Description
2005-04-15	REN	Ceased due to non-payment of the annual fee