ATE203513T1 - Eine familie von verbindungen mit entzündungshemmender und antiviraler aktivität und deren zusammensetzungen alleine oder in verbindung mit inhibitoren der reversen transcriptase zur inhibierung, vermeidung oder eliminierung viraler replikation und methoden zu ihrer verwendung - Google Patents

Eine familie von verbindungen mit entzündungshemmender und antiviraler aktivität und deren zusammensetzungen alleine oder in verbindung mit inhibitoren der reversen transcriptase zur inhibierung, vermeidung oder eliminierung viraler replikation und methoden zu ihrer verwendung

Info

Publication number: ATE203513T1
Authority: AT; Austria
Prior art keywords: compounds; inflammatory; inhibiting; methods; reverse transcriptase
Prior art date: 1995-09-15

Application number

AT96928647T

Other languages

English (en)

Inventor

Farid Hamedi-Sangsari

Fabienne Nugier

Thierry Vallet

Jacques Grange

Jorge Vila

Original Assignee

Cie De Dev Aguettant

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-15

Filing date

1996-09-13

Publication date

2001-08-15

1996-09-13 Application filed by Cie De Dev Aguettant filed Critical Cie De Dev Aguettant

2001-08-15 Application granted granted Critical

2001-08-15 Publication of ATE203513T1 publication Critical patent/ATE203513T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 3
239000000203 mixture Substances 0.000 title abstract 3
230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
230000000840 anti-viral effect Effects 0.000 title abstract 2
230000002401 inhibitory effect Effects 0.000 title abstract 2
239000003419 rna directed dna polymerase inhibitor Substances 0.000 title abstract 2
230000029812 viral genome replication Effects 0.000 title 1
241000700605 Viruses Species 0.000 abstract 2
125000004122 cyclic group Chemical group 0.000 abstract 2
239000000654 additive Substances 0.000 abstract 1
230000000996 additive effect Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000001747 exhibiting effect Effects 0.000 abstract 1
210000005260 human cell Anatomy 0.000 abstract 1
230000010076 replication Effects 0.000 abstract 1
230000001177 retroviral effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000002195 synergetic effect Effects 0.000 abstract 1
241001430294 unidentified retrovirus Species 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyrrole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT96928647T 1995-09-15 1996-09-13 Eine familie von verbindungen mit entzündungshemmender und antiviraler aktivität und deren zusammensetzungen alleine oder in verbindung mit inhibitoren der reversen transcriptase zur inhibierung, vermeidung oder eliminierung viraler replikation und methoden zu ihrer verwendung ATE203513T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US52887995A	1995-09-15	1995-09-15
US08/600,525 US5705522A (en)	1995-09-15	1996-02-13	Compounds having anti-inflammatory and anti-viral activity, compositions of these, alone and in combination with reverse transcriptase inhibitors
PCT/IB1996/000942 WO1997010205A1 (en)	1995-09-15	1996-09-13	A new family of compounds having anti-inflammatory and anti-viral activity and compositions of these, alone and in combination with reverse transcriptase inhibitors, for inhibiting, preventing or eliminating viral replication and methods of using same

Publications (1)

Publication Number	Publication Date
ATE203513T1 true ATE203513T1 (de)	2001-08-15

Family

ID=27062862

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96928647T ATE203513T1 (de)	1995-09-15	1996-09-13	Eine familie von verbindungen mit entzündungshemmender und antiviraler aktivität und deren zusammensetzungen alleine oder in verbindung mit inhibitoren der reversen transcriptase zur inhibierung, vermeidung oder eliminierung viraler replikation und methoden zu ihrer verwendung

Country Status (8)

Country	Link
US (1)	US5705522A (de)
EP (1)	EP0854860B1 (de)
JP (1)	JP2000511871A (de)
AT (1)	ATE203513T1 (de)
AU (1)	AU6835096A (de)
CA (1)	CA2231996A1 (de)
DE (1)	DE69614127D1 (de)
WO (1)	WO1997010205A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2335617C (en) *	1998-06-24	2009-12-15	Novirio Pharmaceuticals Limited	Use of 3'-azido-2',3'-dideoxyuridine in combination with further anti-hiv drugs for the manufacture of a medicament for the treatment of hiv
KR20030005197A (ko) *	2000-02-18	2003-01-17	샤이어 바이오켐 인코포레이티드	뉴클레오시드유도체를 이용한 플라비바이러스 감염의 치료또는 예방 방법
US20050087555A1 (en) *	2003-10-28	2005-04-28	Hatton Jason D.	Fluid dispensing components
WO2007070659A2 (en) *	2005-12-14	2007-06-21	Ambrx, Inc.	Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
HUE037408T2 (hu)	2011-06-10	2018-08-28	Univ Oregon Health & Science	CMV glikoproteinek és rekombináns vektorok

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES8801303A1 (es) *	1985-05-15	1987-12-16	Wellcome Found	Un procedimiento para preparar una formulacion farmaceutica que contiene un 2'3'-didesoxi-nucleosido.
AU570853B2 (en) *	1985-08-26	1988-03-24	United States of America, as represented by the Secretary, U.S. Department of Commerce, The	Inhibition of infectivity and cytopathic effect of htlv-111/ lav by purine bases
US5254539A (en) *	1985-08-26	1993-10-19	U.S. Government, Dept. Of Health And Human Services, C/O National Institutes Of Health	Method of treating HIV with 2',3'-dideoxyinosine
FR2646348A1 (fr) *	1989-04-28	1990-11-02	Inst Nat Sante Rech Med	D-aspartique acide-hydroxamate en tant que medicament
US5571839A (en) *	1989-04-28	1996-11-05	Institut National De La Sante Et De La Recherche Medicale (Inserm)	D-aspartic acid β-hydroxamate for the treatment of viral infections and tumors
GB9208428D0 (en) *	1992-04-16	1992-06-03	Proteus Molecular Design	Synthetic polypeptides
AU685128B2 (en) *	1993-05-21	1998-01-15	Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The	New procedure to block the replication of reverse transcriptase dependent viruses by the use of inhibitors of deoxynucleotides synthesis
AU1249595A (en) *	1993-12-20	1995-07-17	Compagnie De Developpment	Mixtures of dideoxynucleosides and d-aspartic acid beta-hydroxamate for inhibiting retroviral spread

1996
- 1996-02-13 US US08/600,525 patent/US5705522A/en not_active Expired - Fee Related
- 1996-09-13 AU AU68350/96A patent/AU6835096A/en not_active Abandoned
- 1996-09-13 CA CA002231996A patent/CA2231996A1/en not_active Abandoned
- 1996-09-13 DE DE69614127T patent/DE69614127D1/de not_active Expired - Lifetime
- 1996-09-13 JP JP09511797A patent/JP2000511871A/ja active Pending
- 1996-09-13 EP EP96928647A patent/EP0854860B1/de not_active Expired - Lifetime
- 1996-09-13 WO PCT/IB1996/000942 patent/WO1997010205A1/en not_active Ceased
- 1996-09-13 AT AT96928647T patent/ATE203513T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2231996A1 (en)	1997-03-20
EP0854860B1 (de)	2001-07-25
WO1997010205A1 (en)	1997-03-20
JP2000511871A (ja)	2000-09-12
EP0854860A1 (de)	1998-07-29
AU6835096A (en)	1997-04-01
DE69614127D1 (de)	2001-08-30
US5705522A (en)	1998-01-06

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Legal Events

Date	Code	Title	Description
2002-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties