ATE203994T1 - Herstellung von (s)-n-tert-butyl-1,2,3,4- tetrahydroisoquinolin-3-carboxamid - Google Patents

Herstellung von (s)-n-tert-butyl-1,2,3,4- tetrahydroisoquinolin-3-carboxamid

Info

Publication number: ATE203994T1
Authority: AT; Austria
Prior art keywords: tetrahydroisoquinoline; tert; butyl; carboxamide; preparation
Prior art date: 1998-06-26

Application number

AT99928006T

Other languages

English (en)

Inventor

Pietro Bellani

Marco Frigerio

Original Assignee

Clariant Lsm Italia Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-26

Filing date

1999-06-17

Publication date

2001-08-15

1999-06-17 Application filed by Clariant Lsm Italia Spa filed Critical Clariant Lsm Italia Spa

2001-08-15 Application granted granted Critical

2001-08-15 Publication of ATE203994T1 publication Critical patent/ATE203994T1/de

Links

DMJXRYSGXCLCFP-LBPRGKRZSA-N (3s)-n-tert-butyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide Chemical compound C1=CC=C2CN[C@H](C(=O)NC(C)(C)C)CC2=C1 DMJXRYSGXCLCFP-LBPRGKRZSA-N 0.000 title 1
230000015572 biosynthetic process Effects 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
238000003786 synthesis reaction Methods 0.000 abstract 2
BWKMGYQJPOAASG-VIFPVBQESA-N (3s)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid Chemical compound C1=CC=C2CN[C@H](C(=O)O)CC2=C1 BWKMGYQJPOAASG-VIFPVBQESA-N 0.000 abstract 1
RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
ZHNSDZJJTWNYLU-ZDUSSCGKSA-N N-tert-butyl-2-[(3S)-1,2,3,4-tetrahydroisoquinolin-3-yl]acetamide Chemical compound C(C)(C)(C)NC(=O)C[C@H]1NCC2=CC=CC=C2C1 ZHNSDZJJTWNYLU-ZDUSSCGKSA-N 0.000 abstract 1
YBRBMKDOPFTVDT-UHFFFAOYSA-N tert-butylamine Chemical compound CC(C)(C)N YBRBMKDOPFTVDT-UHFFFAOYSA-N 0.000 abstract 1
UCPYLLCMEDAXFR-UHFFFAOYSA-N triphosgene Chemical compound ClC(Cl)(Cl)OC(=O)OC(Cl)(Cl)Cl UCPYLLCMEDAXFR-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)

AT99928006T 1998-06-26 1999-06-17 Herstellung von (s)-n-tert-butyl-1,2,3,4- tetrahydroisoquinolin-3-carboxamid ATE203994T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT1998MI001478A IT1301825B1 (it)	1998-06-26	1998-06-26	Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
PCT/EP1999/004266 WO2000000494A1 (en)	1998-06-26	1999-06-17	Preparation of (s)-n-tert-butyl-1,2,3,4-tetrahydroisoquinoline-3-carboxyamide

Publications (1)

Publication Number	Publication Date
ATE203994T1 true ATE203994T1 (de)	2001-08-15

Family

ID=11380337

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99928006T ATE203994T1 (de)	1998-06-26	1999-06-17	Herstellung von (s)-n-tert-butyl-1,2,3,4- tetrahydroisoquinolin-3-carboxamid

Country Status (13)

Country	Link
US (1)	US6340760B1 (de)
EP (1)	EP1009749B1 (de)
JP (1)	JP2002519351A (de)
KR (1)	KR100630787B1 (de)
AT (1)	ATE203994T1 (de)
AU (1)	AU4515299A (de)
DE (1)	DE69900214T2 (de)
DK (1)	DK1009749T3 (de)
ES (1)	ES2161567T3 (de)
HU (1)	HUP0004916A3 (de)
IT (1)	IT1301825B1 (de)
PT (1)	PT1009749E (de)
WO (1)	WO2000000494A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1313682B1 (it) *	1999-11-25	2002-09-09	Archimica Spa	Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
IT1318986B1 (it)	2000-10-09	2003-09-19	Archimica S P A Ora Clariant L	Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidroisochinolin-3-carbossiammide.
ITMI20040452A1 (it) *	2004-03-09	2004-06-09	Clariant Lsm Italia Spa	Processo per la preparazione di oxcarbazepina
CN1300115C (zh) *	2004-03-26	2007-02-14	厦门大学	一种合成1，2，3，4－四氢异喹啉衍生物的方法
US8772212B2 (en)	2008-08-07	2014-07-08	Conopco, Inc.	Liquid personal cleansing composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5256783A (en) *	1991-09-18	1993-10-26	Hoffmann-La Roche Inc.	Method for producing 2-isoquinoline compounds
ES2135171T5 (es) *	1995-06-30	2006-03-16	Ajinomoto Co., Inc.	Procedimiento para producir amidas opticamente activas.
US5587481A (en) *	1996-02-20	1996-12-24	The Monsanto Company	Preparation of (S)-decahydroisoquinoline-3-carboxylic acid t-butylamide
JPH10291979A (ja) *	1997-04-21	1998-11-04	Ichikawa Gosei Kagaku Kk	１，２，３，４−テトラヒドロイソキノリン−３−カルボン酸ターシャリーブチルアミドの製造方法

1998
- 1998-06-26 IT IT1998MI001478A patent/IT1301825B1/it active IP Right Grant
1999
- 1999-06-17 KR KR1020007001899A patent/KR100630787B1/ko not_active Expired - Fee Related
- 1999-06-17 DK DK99928006T patent/DK1009749T3/da active
- 1999-06-17 JP JP2000557255A patent/JP2002519351A/ja not_active Withdrawn
- 1999-06-17 ES ES99928006T patent/ES2161567T3/es not_active Expired - Lifetime
- 1999-06-17 AT AT99928006T patent/ATE203994T1/de not_active IP Right Cessation
- 1999-06-17 DE DE69900214T patent/DE69900214T2/de not_active Expired - Fee Related
- 1999-06-17 PT PT79103622T patent/PT1009749E/pt unknown
- 1999-06-17 AU AU45152/99A patent/AU4515299A/en not_active Abandoned
- 1999-06-17 WO PCT/EP1999/004266 patent/WO2000000494A1/en not_active Ceased
- 1999-06-17 HU HU0004916A patent/HUP0004916A3/hu active IP Right Revival
- 1999-06-17 EP EP99928006A patent/EP1009749B1/de not_active Expired - Lifetime
2000
- 2000-01-06 US US09/478,690 patent/US6340760B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU4515299A (en)	2000-01-17
DE69900214T2 (de)	2002-05-08
WO2000000494A1 (en)	2000-01-06
EP1009749B1 (de)	2001-08-08
KR100630787B1 (ko)	2006-10-09
JP2002519351A (ja)	2002-07-02
KR20010023266A (ko)	2001-03-26
DK1009749T3 (da)	2001-11-12
US6340760B1 (en)	2002-01-22
EP1009749A1 (de)	2000-06-21
PT1009749E (pt)	2002-01-30
ITMI981478A1 (it)	1999-12-26
HUP0004916A3 (en)	2002-12-28
ES2161567T3 (es)	2001-12-01
HUP0004916A2 (hu)	2001-05-28
DE69900214D1 (de)	2001-09-13
IT1301825B1 (it)	2000-07-07

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Legal Events

Date	Code	Title	Description
2001-12-15	UEP	Publication of translation of european patent specification
2008-03-15	REN	Ceased due to non-payment of the annual fee