DK543787D0 - Antibakterielle midler - Google Patents

Antibakterielle midler

Info

Publication number: DK543787D0
Authority: DK; Denmark
Prior art keywords: antibacterial agents; chem; compounds; disclosed; mpounds
Prior art date: 1986-10-20

Application number

DK543787A

Other languages

English (en)

Other versions

DK543787A (da

Inventor

John Michael Domagala

Thomas Frederick Mich

Joseph Peter Sanchez

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-10-20

Filing date

1987-10-16

Publication date

1987-10-16

1987-10-16 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

1987-10-16 Publication of DK543787D0 publication Critical patent/DK543787D0/da

1988-04-21 Publication of DK543787A publication Critical patent/DK543787A/da

Links

239000003242 anti bacterial agent Substances 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
CSAYVSRENVQAPV-UHFFFAOYSA-N N1=CC=CC2=CC=CC=C21.C1=CC=C2ONC(C(=O)O)=CC2=C1 Chemical class N1=CC=CC2=CC=CC=C21.C1=CC=C2ONC(C(=O)O)=CC2=C1 CSAYVSRENVQAPV-UHFFFAOYSA-N 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)
Quinoline Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK543787A 1986-10-20 1987-10-16 Naphthyridin-, quinolin- og benzoxazincarboxylsyreforbindelser med antibakteriel aktivitet DK543787A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/920,536 US4822801A (en)	1984-07-20	1986-10-20	4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents

Publications (2)

Publication Number	Publication Date
DK543787D0 true DK543787D0 (da)	1987-10-16
DK543787A DK543787A (da)	1988-04-21

Family

ID=25443916

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK543787A DK543787A (da)	1986-10-20	1987-10-16	Naphthyridin-, quinolin- og benzoxazincarboxylsyreforbindelser med antibakteriel aktivitet

Country Status (17)

Country	Link
US (1)	US4822801A (da)
EP (1)	EP0265230B1 (da)
JP (2)	JP2750117B2 (da)
KR (1)	KR880005137A (da)
AT (1)	ATE71375T1 (da)
AU (1)	AU643489B2 (da)
CA (1)	CA1336089C (da)
DE (1)	DE3775882D1 (da)
DK (1)	DK543787A (da)
ES (1)	ES2040261T3 (da)
FI (1)	FI874570A7 (da)
GR (1)	GR3003548T3 (da)
IE (1)	IE64492B1 (da)
NO (1)	NO874350L (da)
PH (3)	PH24199A (da)
PT (1)	PT85943B (da)
ZA (1)	ZA877887B (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
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JPH089597B2 (ja) *	1986-01-21	1996-01-31	杏林製薬株式会社	選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法
US5173484A (en) *	1988-02-05	1992-12-22	Bayer Aktiengesellschaft	Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them
JPH0228178A (ja) *	1988-04-23	1990-01-30	Toyama Chem Co Ltd	新規なピリドンカルボン酸誘導体およびその塩並びにそれらの製造法
KR910003630B1 (ko) *	1988-06-17	1991-06-07	한국과학기술원	벤조일 아세틱 에스테르 유도체 및 그 제조방법
JPH0674261B2 (ja) *	1988-06-21	1994-09-21	塩野義製薬株式会社	キノロンカルボン酸誘導体
AU618823B2 (en) *	1988-07-20	1992-01-09	Sankyo Company Limited	4-oxoquinoline-3-carboxylic acid derivatives, their preparation and their use
DK0525057T3 (da)	1990-04-18	2000-07-31	Procter & Gamble Pharma	Antimikrobielle quinolonyllactamer
ES2167329T3 (es) *	1992-01-31	2002-05-16	Chugai Pharmaceutical Co Ltd	Cristal de hidrato de derivado de acido quinolonacarboxilico.
US5646163A (en) *	1992-10-30	1997-07-08	The Procter & Gamble Company	Quinolone 5-(N-heterosubstituted amino) antimicrobials
KR970704693A (ko) *	1994-07-18	1997-09-06	나가히로 마오미	트리플루오로메틸퀴놀린카르복실산 유도체(trifluoromethylquinolinecarboxylic acid derivative)
US5602254A (en) *	1995-05-26	1997-02-11	Warner-Lambert Company	Method for making quinoline carboxylic acids or naphthyridine carboxylic acids in free base form
DE19652239A1 (de)	1996-12-16	1998-06-18	Bayer Ag	Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen
US6387928B1 (en) *	1997-09-15	2002-05-14	The Procter & Gamble Co.	Antimicrobial quinolones, their compositions and uses
ATE423776T1 (de)	1997-09-15	2009-03-15	Procter & Gamble	Antimikrobielle chinolone, ihre zusammensetzungen und ihre verwendungen
US7098219B2 (en)	2000-08-01	2006-08-29	Wockhart Limited	Inhibitors of cellular efflux pumps of microbes
US6964966B2 (en)	2001-04-25	2005-11-15	Wockhardt Limited	Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6878713B2 (en) *	2001-04-25	2005-04-12	Wockhardt Limited	Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
ATE443064T1 (de) *	2002-03-18	2009-10-15	Kyorin Seiyaku Kk	10-(3-cyclo propyl amino methyl-1-pyrrolidinyl) pyridobenzoxazin carbonsäure derivat mit wirkung gegen resistente bakterien
US6664267B1 (en) *	2002-05-28	2003-12-16	Wockhardt Limited	Crystalline fluoroquinolone arginine salt form
EP1660495B1 (en)	2003-09-04	2007-07-11	Wockhardt Limited	Benzoquinolizine-2-carboxylic acid arginine salt tetrahydrate
SI1666477T1 (sl) *	2003-09-10	2013-10-30	Kyorin Pharmaceutical Co., Ltd.	Derivati 7-(4-substituiran 3-ciklopropilaminometil-1-pirolidinil) kinolonkarboksilne kisline
WO2005111030A1 (en) *	2004-05-12	2005-11-24	Warner-Lambert Company Llc	Quinolone antibacterial agents
US20090156577A1 (en) *	2004-09-09	2009-06-18	Benjamin Davis	7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
US7563805B2 (en) *	2005-05-19	2009-07-21	Daiichi Pharmaceutical Co., Ltd.	Tri-, tetra-substituted-3-aminopyrrolidine derivative
KR101419554B1 (ko)	2006-03-13	2014-07-17	교린 세이야꾸 가부시키 가이샤	Ｇｓｋ３ 억제제로서 아미노퀴놀론
PT2001862E (pt) *	2006-03-28	2011-07-20	Warner Chilcott Co Llc	Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico
WO2007110836A1 (en) *	2006-03-28	2007-10-04	The Procter & Gamble Company	A hydride reduction process for preparing quinolone intermediates
BRPI0709220A2 (pt) *	2006-03-28	2011-07-12	Procter & Gamble	processo de acoplamento para preparo de intermediários de quinolona
US8222407B2 (en) *	2007-05-24	2012-07-17	Kyorin Pharmaceutical Co., Ltd.	Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position
US7902227B2 (en) *	2007-07-27	2011-03-08	Janssen Pharmaceutica Nv.	C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
BRPI0816798A2 (pt)	2007-09-11	2016-10-11	Activx Biosciences Inc	composto, composição farmacêutica, métodos para inibir a ação do glicogênio sintase cinase-3, e para tratar, prevenir ou melhorar uma doença, uso de um composto, e, artigo de fabricação
CN101855229A (zh)	2007-09-12	2010-10-06	埃迪威克斯生物科学公司	作为gsk-3抑制剂的螺环状氨基喹诺酮
EP2222662A4 (en) *	2007-11-15	2011-08-03	Univ Maryland	INHIBITORS OF KYNURENINE AMINO TRANSFERASE
BRPI1008974A2 (pt) *	2009-03-11	2017-06-06	Kyorin Seiyaku Kk	composto, composição farmacêutica, e, método para tratar, prevenir ou melhorar uma doença mediada com gsk-3
US9573902B2 (en) *	2013-02-15	2017-02-21	Laurus Labs Private Ltd.	Process for the preparation of Ivacaftor and its intermediates
KR102213991B1 (ko) *	2014-05-20	2021-02-09	동화약품주식회사	개선된 자보플록사신의 제조방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4049811A (en) *	1968-07-23	1977-09-20	Boehringer Mannheim G.M.B.H.	Compositions using cycloalkano-quinolone derivatives and their method of use
JPS5746986A (en) *	1980-09-02	1982-03-17	Dai Ichi Seiyaku Co Ltd	Pyrido(1,2,3-de)(1,4)benzoxazine derivative
US4665079A (en) *	1984-02-17	1987-05-12	Warner-Lambert Company	Antibacterial agents
US4571396A (en) *	1984-04-16	1986-02-18	Warner-Lambert Company	Antibacterial agents
IE58742B1 (en) *	1984-07-20	1993-11-05	Warner Lambert Co	Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
US4604401A (en) *	1984-07-20	1986-08-05	Warner-Lambert Company	Antibacterial agents III
AU576272B2 (en) *	1984-11-13	1988-08-18	Kyorin Pharmaceutical Co. Ltd.	Quinolone carboxylic acid derivates
AU578793B2 (en) *	1985-02-15	1988-11-03	Dainippon Pharmaceutical Co. Ltd.	Novel 1,8-naphthyridine derivatives and processes for preparation thereof
JPH089597B2 (ja) *	1986-01-21	1996-01-31	杏林製薬株式会社	選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法
JPH0720940B2 (ja) *	1986-02-28	1995-03-08	大日本製薬株式会社	キノリン誘導体の製造法
US4780408A (en) *	1986-03-26	1988-10-25	Colorado State University Research Foundation	Antibody for detection and quantification of trifluralin
JPH0720941B2 (ja) *	1986-03-28	1995-03-08	大日本製薬株式会社	新規キノロン誘導体、そのエステルおよびその塩
EP0242789A3 (en) *	1986-04-25	1990-09-05	Dainippon Pharmaceutical Co., Ltd.	Novel quinoline derivates and processes for preparation thereof
US4771055A (en) *	1986-07-28	1988-09-13	Warner-Lambert Company	7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acids
JPS63152318A (ja) *	1986-08-07	1988-06-24	Dainippon Pharmaceut Co Ltd	抗マイコプラズマ剤

1986
- 1986-10-20 US US06/920,536 patent/US4822801A/en not_active Expired - Lifetime
1987
- 1987-09-18 CA CA000547233A patent/CA1336089C/en not_active Expired - Fee Related
- 1987-09-25 IE IE259087A patent/IE64492B1/en not_active IP Right Cessation
- 1987-10-16 DK DK543787A patent/DK543787A/da not_active Application Discontinuation
- 1987-10-16 FI FI874570A patent/FI874570A7/fi not_active Application Discontinuation
- 1987-10-19 PT PT85943A patent/PT85943B/pt not_active IP Right Cessation
- 1987-10-19 JP JP62261929A patent/JP2750117B2/ja not_active Expired - Fee Related
- 1987-10-19 NO NO874350A patent/NO874350L/no unknown
- 1987-10-20 DE DE8787309267T patent/DE3775882D1/de not_active Expired - Fee Related
- 1987-10-20 KR KR870011656A patent/KR880005137A/ko not_active Ceased
- 1987-10-20 AT AT87309267T patent/ATE71375T1/de not_active IP Right Cessation
- 1987-10-20 ES ES198787309267T patent/ES2040261T3/es not_active Expired - Lifetime
- 1987-10-20 EP EP87309267A patent/EP0265230B1/en not_active Expired - Lifetime
- 1987-10-20 ZA ZA877887A patent/ZA877887B/xx unknown
- 1987-10-20 PH PH35962A patent/PH24199A/en unknown
1989
- 1989-04-03 PH PH38420A patent/PH25459A/en unknown
- 1989-04-03 PH PH38421A patent/PH25423A/en unknown
1991
- 1991-01-07 AU AU69205/91A patent/AU643489B2/en not_active Ceased
1992
- 1992-01-09 GR GR910402252T patent/GR3003548T3/el unknown
1997
- 1997-10-08 JP JP27539997A patent/JP3235539B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ATE71375T1 (de)	1992-01-15
IE64492B1 (en)	1995-08-09
NO874350L (no)	1988-04-21
AU7987987A (en)	1988-04-21
FI874570A7 (fi)	1988-04-21
PT85943A (en)	1987-11-01
IE872590L (en)	1988-04-20
PH25423A (en)	1991-07-01
JPH10114779A (ja)	1998-05-06
US4822801A (en)	1989-04-18
GR3003548T3 (da)	1993-03-16
JP3235539B2 (ja)	2001-12-04
EP0265230A1 (en)	1988-04-27
ZA877887B (en)	1989-05-30
DK543787A (da)	1988-04-21
DE3775882D1 (de)	1992-02-20
AU606618B2 (en)	1991-02-14
AU6920591A (en)	1991-03-28
CA1336089C (en)	1995-06-27
AU643489B2 (en)	1993-11-18
PT85943B (pt)	1990-07-31
JPS63104974A (ja)	1988-05-10
ES2040261T3 (es)	1993-10-16
PH24199A (en)	1990-04-10
EP0265230B1 (en)	1992-01-08
PH25459A (en)	1991-07-01
NO874350D0 (no)	1987-10-19
FI874570A0 (fi)	1987-10-16
KR880005137A (ko)	1988-06-28
JP2750117B2 (ja)	1998-05-13

Legal Events

Date	Code	Title	Description
2003-11-10	AHS	Application shelved for other reasons than non-payment

Publication	Publication Date	Title
FI874570A0 (fi)	1987-10-16	Antibakteriska medel -ii.
NZ212750A (en)	1989-04-26	3-acylamino-2-azetidinone derivatives useful as intermediates in the preparation of antibacterial agents
HUT56379A (en)	1991-08-28	Process for producing a-norsteroid-3-carboxylic acid derivatives and compositions comprising such compounds
EP0181001A3 (en)	1989-04-19	Polypeptide, a process for preparing the same, a pharmaceutical composition containing said polypeptide as well as the use thereof
ES8606282A1 (es)	1986-04-16	Un procedimiento de preparar derivados de acidos quinolin- ynaftiridin-carboxilicos
ATE51617T1 (de)	1990-04-15	Verfahren zur herstellung von 4-phenyl-pyrrolderivaten.
IT1197841B (it)	1988-12-06	Derivati pirido-benzotiazinici ad attivita' antibatterica ed a lunga durata di azione
ATE146472T1 (de)	1997-01-15	Umwandlungsverfahren von lorabef dihydrate in loracarbef monohydrate
SE7906681L (sv)	1980-02-12	Ftalazonderivat
EP0802179A4 (en)	2000-04-05	DERIVATE SUBSTITUTED AMIDINONAPHTHYLESTER
DK0381114T3 (da)	1994-10-24	Exo-3,4-O-benzyliden-3"-demethylchartreusin og salte deraf
ES2095831T3 (es)	1997-03-01	Acidos tetrahidro-4-fenilimino-3-tiofeno-aceticos.
DE58909563D1 (de)	1996-02-22	3-Anilino-2-hydroxycarbonyl-4-thiophenessigsäuren