ATE204176T1 - Verwendung von insulinähnlichen wachstumsfaktoren und analogen zur behandlung von erkrankungen der sehnerven - Google Patents
Verwendung von insulinähnlichen wachstumsfaktoren und analogen zur behandlung von erkrankungen der sehnervenInfo
- Publication number
- ATE204176T1 ATE204176T1 AT92924246T AT92924246T ATE204176T1 AT E204176 T1 ATE204176 T1 AT E204176T1 AT 92924246 T AT92924246 T AT 92924246T AT 92924246 T AT92924246 T AT 92924246T AT E204176 T1 ATE204176 T1 AT E204176T1
- Authority
- AT
- Austria
- Prior art keywords
- analogues
- insulin
- treatment
- growth factors
- optic nerve
- Prior art date
Links
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 title abstract 3
- 102000013275 Somatomedins Human genes 0.000 title 1
- 208000020911 optic nerve disease Diseases 0.000 title 1
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 abstract 2
- 102000048143 Insulin-Like Growth Factor II Human genes 0.000 abstract 2
- 108090001117 Insulin-Like Growth Factor II Proteins 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 210000002569 neuron Anatomy 0.000 abstract 1
- 230000006576 neuronal survival Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 230000002207 retinal effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
- A01N57/20—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
- C07F9/3813—N-Phosphonomethylglycine; Salts or complexes thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/839—Nerves; brain
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Environmental Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Neurology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79069091A | 1991-11-08 | 1991-11-08 | |
| US07/963,329 US6310040B1 (en) | 1991-11-08 | 1992-10-15 | Treating retinal neuronal disorders by the application of insulin-like growth factors and analogs |
| PCT/US1992/009443 WO1993008826A1 (en) | 1991-11-08 | 1992-11-03 | Treating retinal neuronal disorders by the application of insulin-like growth factors and analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE204176T1 true ATE204176T1 (de) | 2001-09-15 |
Family
ID=27121062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92924246T ATE204176T1 (de) | 1991-11-08 | 1992-11-03 | Verwendung von insulinähnlichen wachstumsfaktoren und analogen zur behandlung von erkrankungen der sehnerven |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6310040B1 (de) |
| EP (1) | EP0670729B1 (de) |
| JP (1) | JP3445269B2 (de) |
| AT (1) | ATE204176T1 (de) |
| CA (1) | CA2122340C (de) |
| DE (1) | DE69232008T2 (de) |
| DK (1) | DK0670729T3 (de) |
| ES (1) | ES2160581T3 (de) |
| WO (1) | WO1993008826A1 (de) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6310040B1 (en) | 1991-11-08 | 2001-10-30 | Cephalon, Inc. | Treating retinal neuronal disorders by the application of insulin-like growth factors and analogs |
| AU693489B2 (en) * | 1993-11-15 | 1998-07-02 | Celtrix Pharmaceuticals, Inc. | Method of treating neurological disorders |
| WO1996007744A1 (en) * | 1994-09-08 | 1996-03-14 | Chiron Corporation | A method of improved production of insulin-like growth factor |
| US5712249A (en) * | 1994-09-08 | 1998-01-27 | Ciba-Geigy Corporation | Use of insulin-like growth factors I and II for inhibition of inflammatory response |
| JP3191038B2 (ja) | 1996-06-26 | 2001-07-23 | 輝夫 西田 | 眼科用医薬組成物 |
| WO2000053760A2 (en) * | 1999-03-12 | 2000-09-14 | Genentech, Inc. | Method of preventing the death of retinal neurons and treating ocular diseases |
| US6025368A (en) * | 1997-02-25 | 2000-02-15 | Celtrix Pharmaceuticals, Inc. | Method for treating the symptoms of chronic stress-related disorders using IGF |
| US6015786A (en) * | 1997-02-25 | 2000-01-18 | Celtrix Pharmaceuticals, Inc. | Method for increasing sex steroid levels using IGF or IGF/IGFBP-3 |
| US6514937B1 (en) | 1997-02-25 | 2003-02-04 | Celtrix Pharmaceuticals, Inc. | Method of treating psychological and metabolic disorders using IGF or IGF/IGFBP-3 |
| WO1998042369A1 (fr) * | 1997-03-24 | 1998-10-01 | Fujisawa Pharmaceutical Co., Ltd. | Secretagogues de bile |
| US6121416A (en) | 1997-04-04 | 2000-09-19 | Genentech, Inc. | Insulin-like growth factor agonist molecules |
| US6420518B1 (en) | 1997-04-04 | 2002-07-16 | Genetech, Inc. | Insulin-like growth factor agonist molecules |
| US6331523B1 (en) | 1998-03-12 | 2001-12-18 | Genentech, Inc. | Method of enhancing the survival of retinal neurons and treating ocular diseases using FGF-5 |
| US7173005B2 (en) | 1998-09-02 | 2007-02-06 | Antyra Inc. | Insulin and IGF-1 receptor agonists and antagonists |
| US6875741B2 (en) | 1998-09-02 | 2005-04-05 | Renuka Pillutla | Insulin and IGF-1 receptor agonists and antagonists |
| PT1141014E (pt) | 1999-01-06 | 2005-04-29 | Genentech Inc | Variante mutante do factor de crescimento semelhante a insulina (igf-i) |
| AU6391000A (en) * | 1999-07-28 | 2001-02-19 | Genentech Inc. | Method of preventing the injury or death of retinal cells and treating ocular diseases |
| GB9928323D0 (en) * | 1999-11-30 | 2000-01-26 | Cyclacel Ltd | Peptides |
| US20050245451A1 (en) * | 2000-04-05 | 2005-11-03 | Pincus Matthew R | Peptides selectively lethal to malignant and transformed mammalian cells |
| ES2301547T3 (es) | 2000-05-16 | 2008-07-01 | Genentech, Inc. | Tratamiento de trastornos del cartilago. |
| EP1285000B1 (de) * | 2000-05-31 | 2004-11-24 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Adnf mischungen zur verbesserung der lernfähigkeit und der gedächtnisfunktion |
| NZ548358A (en) | 2001-02-09 | 2008-04-30 | Genentech Inc | Method of identifying agonists of insulin-like growth factor-1 |
| US7605177B2 (en) | 2001-05-24 | 2009-10-20 | Neuren Pharmaceuticals Limited | Effects of glycyl-2 methyl prolyl glutamate on neurodegeneration |
| US7714020B2 (en) | 2001-05-24 | 2010-05-11 | Neuren Pharmaceuticals Limited | Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate |
| AU2002303856A1 (en) | 2001-05-24 | 2002-12-03 | Neuronz Limited | Gpe analogs and peptidomimetics |
| JP4253743B2 (ja) * | 2001-12-03 | 2009-04-15 | 輝夫 西田 | 新規ペプチドおよびその医薬用途 |
| TWI305778B (en) * | 2001-12-03 | 2009-02-01 | Nishida Teruo | Peptides of an expressing unit for igf-i minimal activity and their pharmaceutical use |
| EP1841443A4 (de) * | 2005-01-11 | 2012-05-02 | Heart Failure Technologies Inc | Verfahren und system zur behandlung von herzfehlern |
| JP2008538501A (ja) | 2005-04-20 | 2008-10-30 | オークランド ユニサービシーズ リミティド | ベシキュリン |
| US8309057B2 (en) * | 2005-06-10 | 2012-11-13 | The Invention Science Fund I, Llc | Methods for elevating neurotrophic agents |
| WO2007102686A1 (en) * | 2006-03-06 | 2007-09-13 | Caregen Co., Ltd | Peptides having activities of insulin like growth factor-1 and their uses |
| EP2224961A1 (de) * | 2007-11-26 | 2010-09-08 | The Research Foundation of the State University of New York | Kleinmolekülige krebsbehandlungen, die nekrose in krebszellen verursachen, aber normale zellen nicht angreifen |
| US20110223147A1 (en) | 2008-05-07 | 2011-09-15 | Zystor Therapeutics, Inc. | Lysosomal targeting peptides and uses thereof |
| US9132202B2 (en) | 2009-07-17 | 2015-09-15 | Aaron T. Tabor | Compositions and methods for genetic modification of cells having cosmetic function to enhance cosmetic appearance |
| WO2011011073A1 (en) * | 2009-07-22 | 2011-01-27 | Ipsen Pharma S.A.S. | Site-specific pegylated or site-specific lipidated igf-1 and analogues of igf-1 |
| BR112012001363A2 (pt) | 2009-07-22 | 2016-11-08 | Ipsen Pharma Sas | análogo de igf-1, composição farmacêutica,e, método para tratar condições ou doenças mediadas pela ligação do receptor de igf-1 |
| TWI490371B (zh) | 2009-07-28 | 2015-07-01 | Industrie De Nora Spa | 電解應用上的電極及其製法以及在電極表面上陽極釋氧之電解法和電冶法 |
| EP2509596B1 (de) | 2009-12-08 | 2019-08-28 | Case Western Reserve University | Gamma aminosäure zur behandlung von augenerkrankungen |
| KR101669140B1 (ko) * | 2015-04-28 | 2016-10-26 | (주)케어젠 | 항비만 및 항당뇨 효능을 갖는 펩타이드 및 이의 용도 |
| CN112236162A (zh) | 2018-04-06 | 2021-01-15 | 昂科莱奇公司 | 用于裂解选择性癌细胞的组合物 |
| CN111763680A (zh) * | 2019-05-22 | 2020-10-13 | 杭州杰迪生物科技有限公司 | 一种人胰岛素样生长因子-i或其类似物的制备方法、编码基因、表达载体及宿主细胞 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0720993B2 (ja) * | 1985-08-22 | 1995-03-08 | グロペップ プロプライエタリー リミテッド | 生長因子 |
| US4783524A (en) | 1985-09-17 | 1988-11-08 | Monsanto Company | Growth factors |
| SE8505920D0 (sv) | 1985-12-13 | 1985-12-13 | Kabigen Ab | New protein and its use |
| ATE112684T1 (de) | 1987-04-28 | 1994-10-15 | Boehringer Mannheim Gmbh | Verwendung von igf-ii zur behandlung von knochenkrankheiten. |
| SE8703625D0 (sv) * | 1987-09-18 | 1987-09-18 | Kabivitrum Ab | New medical use |
| WO1989005822A1 (en) | 1987-12-24 | 1989-06-29 | Gropep Pty. Ltd. | Peptide analogues of insulin-like growth factor 1 (igf-1) or factor 2 (igf-2) |
| US5652214A (en) * | 1989-06-05 | 1997-07-29 | Cephalon, Inc. | Treating disorders by application of insulin-like growth factors and analogs |
| US5093317A (en) * | 1989-06-05 | 1992-03-03 | Cephalon, Inc. | Treating disorders by application of insulin-like growth factor |
| EP0597033B1 (de) * | 1991-08-01 | 1997-04-09 | Genentech, Inc. | IGF-I zur Verbesserung der neuronale Lage |
| US6310040B1 (en) | 1991-11-08 | 2001-10-30 | Cephalon, Inc. | Treating retinal neuronal disorders by the application of insulin-like growth factors and analogs |
-
1992
- 1992-10-15 US US07/963,329 patent/US6310040B1/en not_active Expired - Lifetime
- 1992-11-03 DE DE69232008T patent/DE69232008T2/de not_active Expired - Lifetime
- 1992-11-03 JP JP50868193A patent/JP3445269B2/ja not_active Expired - Lifetime
- 1992-11-03 AT AT92924246T patent/ATE204176T1/de active
- 1992-11-03 ES ES92924246T patent/ES2160581T3/es not_active Expired - Lifetime
- 1992-11-03 EP EP92924246A patent/EP0670729B1/de not_active Expired - Lifetime
- 1992-11-03 WO PCT/US1992/009443 patent/WO1993008826A1/en not_active Ceased
- 1992-11-03 CA CA002122340A patent/CA2122340C/en not_active Expired - Lifetime
- 1992-11-03 DK DK92924246T patent/DK0670729T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2160581T3 (es) | 2001-11-16 |
| CA2122340C (en) | 2007-06-12 |
| DE69232008D1 (de) | 2001-09-20 |
| US6310040B1 (en) | 2001-10-30 |
| JP3445269B2 (ja) | 2003-09-08 |
| EP0670729A1 (de) | 1995-09-13 |
| EP0670729A4 (de) | 1995-05-10 |
| DE69232008T2 (de) | 2001-11-29 |
| DK0670729T3 (da) | 2001-12-10 |
| JPH07500839A (ja) | 1995-01-26 |
| EP0670729B1 (de) | 2001-08-16 |
| CA2122340A1 (en) | 1993-05-13 |
| WO1993008826A1 (en) | 1993-05-13 |
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