ATE204336T1 - Verbesserte methode zur selektion spezifischer bakteriophagen - Google Patents

Verbesserte methode zur selektion spezifischer bakteriophagen

Info

Publication number
ATE204336T1
ATE204336T1 AT96901168T AT96901168T ATE204336T1 AT E204336 T1 ATE204336 T1 AT E204336T1 AT 96901168 T AT96901168 T AT 96901168T AT 96901168 T AT96901168 T AT 96901168T AT E204336 T1 ATE204336 T1 AT E204336T1
Authority
AT
Austria
Prior art keywords
pct
improved method
phage
sec
molecule
Prior art date
Application number
AT96901168T
Other languages
English (en)
Inventor
Carl A K Borrebaeck
Original Assignee
Bioinvent Int Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioinvent Int Ab filed Critical Bioinvent Int Ab
Application granted granted Critical
Publication of ATE204336T1 publication Critical patent/ATE204336T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT96901168T 1995-01-17 1996-01-15 Verbesserte methode zur selektion spezifischer bakteriophagen ATE204336T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9500851.2A GB9500851D0 (en) 1995-01-17 1995-01-17 Method of selecting specific bacteriophages
PCT/SE1996/000030 WO1996022393A1 (en) 1995-01-17 1996-01-15 Improved method of selecting specific bacteriophages

Publications (1)

Publication Number Publication Date
ATE204336T1 true ATE204336T1 (de) 2001-09-15

Family

ID=10768125

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96901168T ATE204336T1 (de) 1995-01-17 1996-01-15 Verbesserte methode zur selektion spezifischer bakteriophagen

Country Status (9)

Country Link
US (1) US6027930A (de)
EP (1) EP0805877B1 (de)
JP (1) JPH11503001A (de)
AT (1) ATE204336T1 (de)
AU (1) AU705802B2 (de)
CA (1) CA2210567A1 (de)
DE (1) DE69614510T2 (de)
GB (1) GB9500851D0 (de)
WO (1) WO1996022393A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2113940T3 (es) * 1990-12-03 1998-05-16 Genentech Inc Metodo de enriquecimiento para variantes de proteinas con propiedades de union alteradas.
GB9716900D0 (en) * 1997-08-08 1997-10-15 Bioinvent Int Ab Method for selecting phage displaying ligand binders
US7435549B1 (en) * 1997-11-17 2008-10-14 Micromet Ag Method of identifying binding site domains that retain the capacity of binding to an epitope
CA2334170A1 (en) 1998-07-27 2000-02-10 Genentech, Inc. Improved transformation efficiency in phage display through modification of a coat protein
EP2039368A3 (de) 1999-04-30 2009-04-01 La Jolla Institute For Allergy And Immunology Verfahren zur Vorbeugung der Reaktivierung von latenten Viren und Überwachung der Virenreplikation
US6472147B1 (en) 1999-05-25 2002-10-29 The Scripps Research Institute Methods for display of heterodimeric proteins on filamentous phage using pVII and pIX, compositions, vectors and combinatorial libraries
DK1402025T3 (da) * 2001-06-15 2006-06-06 Crucell Holland Bv Kimære fager
US7070926B2 (en) * 2001-06-15 2006-07-04 Crucell Holland B.V. Chimaeric phages
DE60218473T2 (de) * 2001-07-18 2007-11-08 Instytut Immunologii I Terapii Doswiadczalnej - Pan Verfahren zur herstellung polyvalenter bakteriophagenpräparationen zur behandlung bakterieller infektionen
US6833441B2 (en) * 2001-08-01 2004-12-21 Abmaxis, Inc. Compositions and methods for generating chimeric heteromultimers
KR100458083B1 (ko) * 2001-08-29 2004-11-18 주식회사 아이지세라피 파아지 디스플레이 라이브러리로부터 특정 이종 단백질의효율적인 분리를 위한 개선된 헬퍼 파아지 시스템
US7175983B2 (en) * 2001-11-02 2007-02-13 Abmaxis, Inc. Adapter-directed display systems
DE10238846A1 (de) * 2002-08-20 2004-03-04 Nemod Immuntherapie Ag Aktive Fusionsproteine und Verfahren zu ihrer Herstellung
US8198034B2 (en) 2008-03-14 2012-06-12 Allergan, Inc. Immuno-based botulinum toxin serotype A activity assays
PL215522B1 (pl) 2008-09-29 2013-12-31 Inst Immunologii I Terapii Doswiadczalnej Pan Nowe szczepy bakteriofagów do leczenia zakazen bakteryjnych, zwlaszcza szczepami bakterii lekoopornych rodzaju Enterococcus
WO2010105236A1 (en) 2009-03-13 2010-09-16 Allergan, Inc. Immuno-based retargeted endopeptidase activity assays
PL212258B1 (pl) 2010-06-20 2012-09-28 Inst Immunologii I Terapii Doswiadczalnej Pan Nowe szczepy bakteriofagów do leczenia zakazen bakteryjnych, zwlaszcza szczepami bakterii lekoopornych rodzaju Stenotrophomonas
WO2014150870A2 (en) 2013-03-15 2014-09-25 Altria Client Services Inc. Bacteriophage and methods of making and using
CA2932788A1 (en) 2013-12-08 2015-06-11 Peptcell Limited Hiv antigens and antibodies and compositions, methods and uses thereof
WO2016123425A1 (en) 2015-01-29 2016-08-04 Altria Client Services Llc Endolysin from bacteriophage against geobacillus and methods of using
WO2016123427A1 (en) 2015-01-29 2016-08-04 Altria Client Services Llc Bacteriophage and methods of using
EP3312290A1 (de) 2016-10-18 2018-04-25 Ipsen Biopharm Limited Zellulärer vamp-spaltungstest
WO2019017967A1 (en) * 2017-07-21 2019-01-24 Angela Belcher MODIFIED BACTERIOPHAGE SYSTEMS
US10987388B2 (en) 2017-07-21 2021-04-27 Massachusetts Institute Of Technology Homogeneous engineered phage populations
EP3692370A2 (de) 2017-10-04 2020-08-12 OPKO Pharmaceuticals, LLC Artikel und verfahren zur personalisierten krebstherapie
CN113388585B (zh) * 2021-06-10 2024-05-14 江苏农牧科技职业学院 一种噬菌体高滴度培养方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0614989A1 (de) * 1993-02-17 1994-09-14 MorphoSys AG Verfahren für in vivo Selektion von Ligandenbindende Proteine
SE9304060D0 (sv) * 1993-12-06 1993-12-06 Bioinvent Int Ab Sätt att selektera specifika bakteriofager

Also Published As

Publication number Publication date
JPH11503001A (ja) 1999-03-23
WO1996022393A1 (en) 1996-07-25
AU705802B2 (en) 1999-06-03
DE69614510T2 (de) 2002-05-08
DE69614510D1 (de) 2001-09-20
CA2210567A1 (en) 1996-07-25
EP0805877A1 (de) 1997-11-12
AU4499296A (en) 1996-08-07
US6027930A (en) 2000-02-22
GB9500851D0 (en) 1995-03-08
EP0805877B1 (de) 2001-08-16

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