ATE205489T1 - N-substituierte azaheterocyclische carbonsäuren und ihre alkylester - Google Patents
N-substituierte azaheterocyclische carbonsäuren und ihre alkylesterInfo
- Publication number
- ATE205489T1 ATE205489T1 AT96907326T AT96907326T ATE205489T1 AT E205489 T1 ATE205489 T1 AT E205489T1 AT 96907326 T AT96907326 T AT 96907326T AT 96907326 T AT96907326 T AT 96907326T AT E205489 T1 ATE205489 T1 AT E205489T1
- Authority
- AT
- Austria
- Prior art keywords
- carboxylic acids
- alkylesters
- azaheterocyclic carboxylic
- substituted azaheterocyclic
- substituted
- Prior art date
Links
- 150000001735 carboxylic acids Chemical class 0.000 title abstract 2
- 208000007920 Neurogenic Inflammation Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000000917 hyperalgesic effect Effects 0.000 abstract 1
- 230000004968 inflammatory condition Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 230000001991 pathophysiological effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
- 210000001170 unmyelinated nerve fiber Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK40395 | 1995-04-07 | ||
| DK100695 | 1995-09-11 | ||
| PCT/DK1996/000138 WO1996031497A1 (en) | 1995-04-07 | 1996-04-01 | Novel heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE205489T1 true ATE205489T1 (de) | 2001-09-15 |
Family
ID=26063927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96907326T ATE205489T1 (de) | 1995-04-07 | 1996-04-01 | N-substituierte azaheterocyclische carbonsäuren und ihre alkylester |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US5698551A (de) |
| EP (1) | EP0820450B1 (de) |
| JP (1) | JPH11503126A (de) |
| AT (1) | ATE205489T1 (de) |
| AU (1) | AU5100296A (de) |
| CA (1) | CA2217206A1 (de) |
| DE (1) | DE69615169D1 (de) |
| IL (1) | IL117816A0 (de) |
| WO (1) | WO1996031497A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5952352A (en) * | 1995-04-07 | 1999-09-14 | Novo Nordisk A/S | Heterocyclic compounds |
| AR015446A1 (es) * | 1997-09-19 | 2001-05-02 | Smithkline Beecham Corp | Antagonistas de receptores de vitronectina, composicion farmaceutica que los contiene, procedimiento para su preparacion, su uso para la elaboracion de unmedicamento y compuestos intermediarios |
| US6576643B2 (en) | 1997-09-19 | 2003-06-10 | Smithkline Beecham Corporation | Vitronectin receptor antagonists |
| US6214816B1 (en) | 1998-03-17 | 2001-04-10 | Novo Nordisk A/S | Heterocyclic compounds |
| EP1071679A1 (de) * | 1998-03-17 | 2001-01-31 | Novo Nordisk A/S | Neue heterocyclen |
| US6705675B1 (en) * | 2000-05-08 | 2004-03-16 | Graco Children's Products Inc. | Adjustable child seat for toddlers to small children |
| US20040220167A1 (en) * | 2003-05-02 | 2004-11-04 | Nasrollah Samiy | Methods of treating neuralgic pain |
| US7417040B2 (en) * | 2004-03-01 | 2008-08-26 | Bristol-Myers Squibb Company | Fused tricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3 |
| US7378426B2 (en) * | 2004-03-01 | 2008-05-27 | Bristol-Myers Squibb Company | Fused heterotricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3 |
| TW200615273A (en) | 2004-11-10 | 2006-05-16 | Nicholas Piramal India Ltd | Fused tricyclic compounds as inhibitors of tumor necrosis factor-alpha |
| US7292323B2 (en) * | 2004-11-12 | 2007-11-06 | Alcon, Inc. | Optical fiber detection method and system |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1084267B (de) * | 1955-12-28 | 1960-06-30 | Cilag Chemie | Verfahren zur Herstellung von 1-Aza-[2, 3:5, 6]-dibenzocycloheptadien-derivaten, deren Salzen und quaternaeren Ammoniumverbindungen |
| US2861987A (en) * | 1955-12-28 | 1958-11-25 | Cilag Ltd | New diphenyl methane- and 1-aza-[2,3:5,6]-dibenzocy cloheptadiene derivatives, theiracid salts and quaternary salts and the production thereof |
| BE664609A (de) * | 1964-06-01 | |||
| US3336293A (en) * | 1964-11-06 | 1967-08-15 | Searle & Co | Complex amides of 5, 6-dihydrophenanthridine-5-carboxylic acid, 5, 6-dihydro-11h-dibenz[b, e]azepine-5-carboxylic acid, and related compounds |
| US3514443A (en) * | 1965-01-22 | 1970-05-26 | Squibb & Sons Inc | 5-(substituted amino-lower alkylene)-5,6-dihydrodibenz(b,f)azocines |
| US3803143A (en) * | 1969-09-08 | 1974-04-09 | Eisai Co Ltd | 6-amino alkylene 6,7-dihydro-5h-dibenzo (b,g),(1,5)thiazocines |
| JPS57106673A (en) * | 1980-12-24 | 1982-07-02 | Chugai Pharmaceut Co Ltd | Dibenzo(b,f)(1,4)oxazepin derivative |
| GB2094790B (en) * | 1981-03-13 | 1985-10-09 | Spofa Vereinigte Pharma Werke | Tricycle compounds |
| FR2512024A1 (fr) * | 1981-08-27 | 1983-03-04 | Adir | Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant |
| EP0332246A1 (de) * | 1988-03-11 | 1989-09-13 | Akzo N.V. | Trizyklische Amin-Derivate |
| DK93791D0 (da) * | 1991-05-17 | 1991-05-17 | Novo Nordisk As | Nye heterocykliske carboxylsyrer |
| GB9120640D0 (en) * | 1991-09-27 | 1991-11-06 | Ici Plc | Tricyclic heterocycles |
| US5354747A (en) * | 1993-06-16 | 1994-10-11 | G. D. Searle & Co. | 2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use |
| MY113463A (en) * | 1994-01-04 | 2002-03-30 | Novo Nordisk As | Novel heterocyclic compounds |
| US5602124A (en) * | 1994-12-12 | 1997-02-11 | Allelix Biopharmaceuticals, Inc. | 5-HT2 receptor ligands |
-
1996
- 1996-03-29 US US08/623,807 patent/US5698551A/en not_active Expired - Fee Related
- 1996-04-01 EP EP96907326A patent/EP0820450B1/de not_active Expired - Lifetime
- 1996-04-01 DE DE69615169T patent/DE69615169D1/de not_active Expired - Lifetime
- 1996-04-01 CA CA002217206A patent/CA2217206A1/en not_active Abandoned
- 1996-04-01 AU AU51002/96A patent/AU5100296A/en not_active Abandoned
- 1996-04-01 AT AT96907326T patent/ATE205489T1/de active
- 1996-04-01 JP JP8529867A patent/JPH11503126A/ja active Pending
- 1996-04-01 WO PCT/DK1996/000138 patent/WO1996031497A1/en not_active Ceased
- 1996-04-03 IL IL11781696A patent/IL117816A0/xx unknown
-
1997
- 1997-05-27 US US08/863,257 patent/US5780486A/en not_active Expired - Fee Related
- 1997-05-27 US US08/863,746 patent/US5846968A/en not_active Expired - Fee Related
- 1997-05-27 US US08/863,749 patent/US5747481A/en not_active Expired - Fee Related
- 1997-05-27 US US08/863,751 patent/US5750518A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU5100296A (en) | 1996-10-23 |
| US5750518A (en) | 1998-05-12 |
| EP0820450A1 (de) | 1998-01-28 |
| US5698551A (en) | 1997-12-16 |
| US5780486A (en) | 1998-07-14 |
| JPH11503126A (ja) | 1999-03-23 |
| IL117816A0 (en) | 1996-08-04 |
| EP0820450B1 (de) | 2001-09-12 |
| CA2217206A1 (en) | 1996-10-10 |
| US5846968A (en) | 1998-12-08 |
| WO1996031497A1 (en) | 1996-10-10 |
| DE69615169D1 (de) | 2001-10-18 |
| US5747481A (en) | 1998-05-05 |
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