ATE205538T1 - Genregulatorische sequenzen von cd4, welche spezifisch in reifen t-zellen exprimiert werden - Google Patents

Genregulatorische sequenzen von cd4, welche spezifisch in reifen t-zellen exprimiert werden

Info

Publication number
ATE205538T1
ATE205538T1 AT96925809T AT96925809T ATE205538T1 AT E205538 T1 ATE205538 T1 AT E205538T1 AT 96925809 T AT96925809 T AT 96925809T AT 96925809 T AT96925809 T AT 96925809T AT E205538 T1 ATE205538 T1 AT E205538T1
Authority
AT
Austria
Prior art keywords
mature
regulatory sequences
cells
specifically expressed
gene regulatory
Prior art date
Application number
AT96925809T
Other languages
English (en)
Inventor
David Klatzmann
Patrick Salmon
Olivier Boyer
Original Assignee
Univ Paris Curie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Paris Curie filed Critical Univ Paris Curie
Application granted granted Critical
Publication of ATE205538T1 publication Critical patent/ATE205538T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C12N9/1211—Thymidine kinase (2.7.1.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT96925809T 1995-07-17 1996-07-17 Genregulatorische sequenzen von cd4, welche spezifisch in reifen t-zellen exprimiert werden ATE205538T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9508616A FR2736931B1 (fr) 1995-07-17 1995-07-17 Sequences regulatrices issues du gene cd4 et a expression specifique dans les lymphocytes t matures
PCT/FR1996/001122 WO1997004118A1 (fr) 1995-07-17 1996-07-17 Sequences regulatrices issues du gene cd4 et a expression specifique dans les lymphocytes t matures

Publications (1)

Publication Number Publication Date
ATE205538T1 true ATE205538T1 (de) 2001-09-15

Family

ID=9481044

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96925809T ATE205538T1 (de) 1995-07-17 1996-07-17 Genregulatorische sequenzen von cd4, welche spezifisch in reifen t-zellen exprimiert werden

Country Status (9)

Country Link
US (1) US6333171B1 (de)
EP (1) EP0839206B1 (de)
JP (1) JPH11509415A (de)
AT (1) ATE205538T1 (de)
CA (1) CA2227035A1 (de)
DE (1) DE69615201T2 (de)
ES (1) ES2164907T3 (de)
FR (1) FR2736931B1 (de)
WO (1) WO1997004118A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9807935D0 (en) 1998-04-14 1998-06-10 Univ Edinburgh Lineage specific cells and progenitor cells
US7462485B2 (en) * 2005-10-07 2008-12-09 Glaser Lawrence F Modified erythrocytes and uses thereof
DK2282764T3 (da) * 2008-04-22 2019-10-14 Vib Vzw Leverspecifikke nukleinsyreregulerende elementer samt fremgangsmåder og anvendelser heraf
JP6273653B2 (ja) * 2015-10-23 2018-02-07 学校法人北里研究所 大腸炎又は大腸癌モデル非ヒト動物及びその利用
AU2020218546A1 (en) * 2019-02-08 2021-09-09 Dna Twopointo Inc. Transposon-based modifications of immune cells
US12419913B2 (en) 2019-02-08 2025-09-23 Dna Twopointo, Inc. Modification of CAR-T cells

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06505401A (ja) 1991-10-30 1994-06-23 ユニベルシテ・ピエール・エ・マリ・キュリー（パリ６） ウイルス、特に病原性レトロウイルスによって誘発される疾病の予防または治療のための形質転換された細胞
FR2683226B1 (fr) 1991-10-30 1995-06-09 Univ Paris Curie Cellules piegees a l'egard d'antigenes provoquant le dysfonctionnement du systeme immunitaire, medicaments pour la prevention ou le traitement de maladies induites par ces dysfonctionnements.
FR2699191B1 (fr) 1992-12-16 1995-02-10 Univ Paris Curie Nouveaux vecteurs rétroviraux, lignées cellulaires les contenant, et leur utilisation dans le traitement des tumeurs.
FR2716459B1 (fr) 1994-02-22 1996-05-10 Univ Paris Curie Système hôte-vecteur utilisable en thérapie génique.
EP0758387B1 (de) * 1994-05-02 2001-12-19 University of Washington Thymidin-kinase-mutanten

Also Published As

Publication number Publication date
FR2736931B1 (fr) 1997-09-19
US6333171B1 (en) 2001-12-25
ES2164907T3 (es) 2002-03-01
WO1997004118A1 (fr) 1997-02-06
EP0839206A1 (de) 1998-05-06
CA2227035A1 (fr) 1997-02-06
EP0839206B1 (de) 2001-09-12
DE69615201D1 (de) 2001-10-18
DE69615201T2 (de) 2002-05-02
JPH11509415A (ja) 1999-08-24
FR2736931A1 (fr) 1997-01-24

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Legal Events

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