ATE206059T1 - Heparin-beschichtete medizinische geräte zum intravenösen gebrauch, die heparin-bindende wachstumfaktor-konjugate enthalten - Google Patents

Heparin-beschichtete medizinische geräte zum intravenösen gebrauch, die heparin-bindende wachstumfaktor-konjugate enthalten

Info

Publication number: ATE206059T1
Authority: AT; Austria
Prior art keywords: heparin; growth factor; medical devices; binding growth; use containing
Prior art date: 1996-06-24

Application number

AT97933150T

Other languages

English (en)

Inventor

Glenn Pierce

J Andrew Baird

Original Assignee

Selective Genetics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-24

Filing date

1997-06-20

Publication date

2001-10-15

1997-06-20 Application filed by Selective Genetics Inc filed Critical Selective Genetics Inc

2001-10-15 Application granted granted Critical

2001-10-15 Publication of ATE206059T1 publication Critical patent/ATE206059T1/de

Links

102100031000 Hepatoma-derived growth factor Human genes 0.000 title 1
101001083798 Homo sapiens Hepatoma-derived growth factor Proteins 0.000 title 1
238000001990 intravenous administration Methods 0.000 title 1
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 4
229960002897 heparin Drugs 0.000 abstract 4
229920000669 heparin Polymers 0.000 abstract 4
230000004663 cell proliferation Effects 0.000 abstract 1
229940127089 cytotoxic agent Drugs 0.000 abstract 1
239000002254 cytotoxic agent Substances 0.000 abstract 1
208000037803 restenosis Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/236—Glycosaminoglycans, e.g. heparin, hyaluronic acid, chondroitin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Surgery (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Dermatology (AREA)
Oral & Maxillofacial Surgery (AREA)
Transplantation (AREA)
Hematology (AREA)
Materials Engineering (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Materials For Medical Uses (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

AT97933150T 1996-06-24 1997-06-20 Heparin-beschichtete medizinische geräte zum intravenösen gebrauch, die heparin-bindende wachstumfaktor-konjugate enthalten ATE206059T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US67235396A	1996-06-24	1996-06-24
PCT/US1997/010685 WO1997049434A2 (en)	1996-06-24	1997-06-20	Heparinized medical devices containing heparin-binding growth factor conjugates

Publications (1)

Publication Number	Publication Date
ATE206059T1 true ATE206059T1 (de)	2001-10-15

Family

ID=24698186

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97933150T ATE206059T1 (de)	1996-06-24	1997-06-20	Heparin-beschichtete medizinische geräte zum intravenösen gebrauch, die heparin-bindende wachstumfaktor-konjugate enthalten

Country Status (7)

Country	Link
EP (1)	EP0923387B1 (de)
JP (1)	JP2002515784A (de)
AT (1)	ATE206059T1 (de)
AU (1)	AU3641297A (de)
CA (1)	CA2258154A1 (de)
DE (1)	DE69706998T2 (de)
WO (1)	WO1997049434A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU6140299A (en)	1998-09-10	2000-04-03	Percardia, Inc.	Tmr shunt
EP1330516B1 (de) *	2000-11-03	2007-01-17	The Regents Of The University Of Michigan	Oberflächentransfektion und expressionsverfahren
DK1435877T3 (da)	2001-10-15	2009-08-03	Hemoteq Ag	Overtrækning af stents for at forhindre restenose
US8414907B2 (en) *	2005-04-28	2013-04-09	Warsaw Orthopedic, Inc.	Coatings on medical implants to guide soft tissue healing
US9119901B2 (en)	2005-04-28	2015-09-01	Warsaw Orthopedic, Inc.	Surface treatments for promoting selective tissue attachment to medical impants
PT2043662E (pt) *	2006-07-26	2015-11-25	Intrexon Corp	Métodos e composições para tratamento de doença
US20090226501A1 (en) *	2007-12-07	2009-09-10	Boston Scientific Scimed, Inc.	Drug coated stent with endosome-disrupting conjugate
WO2010118352A1 (en)	2009-04-09	2010-10-14	Arizona Board Of Reagents On Behalf Of The University Of Arizona	Cellular seeding and co-culture of a three dimensional fibroblast construct
JP2020524002A (ja)	2017-06-16	2020-08-13	エイブリィセラピューティクスインコーポレイテッド	三次元組織組成物及び使用方法
EP3955955B1 (de)	2019-04-19	2025-02-26	Synerkine Pharma B.V.	Fusionsprotein mit il13
JP7837557B2 (ja) *	2019-07-23	2026-03-31	ロンギチュードセラピューティクスエッセエッレエッレ	治療用化合物の血小板促進型送達

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5191067A (en) *	1989-04-27	1993-03-02	The Salk Institute For Biological Studies	Fibroblast growth factor conjugates
CA2089820C (en) *	1990-09-19	1999-01-19	Paul Calabresi	Treatment of tumorigenic pathophysiological conditions with fgf-cytotoxic conjugates
EP0565620B1 (de) *	1991-01-03	1995-09-20	The Salk Institute For Biological Studies	Mitotoxin zur behandlung von gefässbeschädigung
US5599352A (en) *	1992-03-19	1997-02-04	Medtronic, Inc.	Method of making a drug eluting stent
US5916772A (en) *	1992-06-16	1999-06-29	Whittier Institute For Diabetes And Endocrinology	Recombinant production of saporin-containing proteins
US5585361A (en) *	1994-06-07	1996-12-17	Genzyme Corporation	Methods for the inhibition of platelet adherence and aggregation
AU3374795A (en) *	1994-08-29	1996-03-22	Prizm Pharmaceuticals, Inc.	Conjugates of vascular endothelial growth factor with targeted agents
WO1996008274A2 (en) *	1994-09-13	1996-03-21	Prizm Pharmaceuticals, Inc.	Conjugates of heparin-binding epidermal growth factor-like growth factor with targeted agents
US5637113A (en) *	1994-12-13	1997-06-10	Advanced Cardiovascular Systems, Inc.	Polymer film for wrapping a stent structure

1997
- 1997-06-20 JP JP50336798A patent/JP2002515784A/ja active Pending
- 1997-06-20 AT AT97933150T patent/ATE206059T1/de not_active IP Right Cessation
- 1997-06-20 AU AU36412/97A patent/AU3641297A/en not_active Abandoned
- 1997-06-20 WO PCT/US1997/010685 patent/WO1997049434A2/en not_active Ceased
- 1997-06-20 DE DE69706998T patent/DE69706998T2/de not_active Expired - Fee Related
- 1997-06-20 CA CA002258154A patent/CA2258154A1/en not_active Abandoned
- 1997-06-20 EP EP97933150A patent/EP0923387B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
WO1997049434A3 (en)	1998-02-26
AU3641297A (en)	1998-01-14
EP0923387B1 (de)	2001-09-26
JP2002515784A (ja)	2002-05-28
CA2258154A1 (en)	1997-12-31
EP0923387A2 (de)	1999-06-23
WO1997049434A2 (en)	1997-12-31
DE69706998D1 (de)	2001-10-31
DE69706998T2 (de)	2002-07-04

Legal Events

Date	Code	Title	Description
2002-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DK1014888T3 (da)	2008-12-15	Middel til placering af en protese
ATE349976T1 (de)	2007-01-15	Mikrostruktur-stentstruktur
IL131063A0 (en)	2001-01-28	Bistable spring construction for a stent and other medical apparatus
DE69426612D1 (de)	2001-03-01	Katheter zum Anbringen eines Stents
CA2326317A1 (en)	1999-10-07	Expandable unit cell and intraluminal stent
DE69828379D1 (de)	2005-02-03	Platte für orthopädischen fixateur
DE60031793D1 (de)	2006-12-21	Doxorubicin- und daunorubicin-enthaltende, zytotoxische mittel und deren therapeutische anwendung
BR0203650A (pt)	2003-06-03	Estentor de auto-articulação
DK1242401T3 (da)	2007-05-07	Cytotoksiske midler, der omfatter taxaner, og den terapeutiske anvendelse deraf
TR199701212T1 (xx)	1998-03-21	�drar� tutamama halinin tedavisi i�in alfa IL- agonistlerinin kullan�lmas�.
MX9301082A (es)	1993-09-01	Articulo absorbente con accesorio de cintura elastica y absorbencia mejorada.
DE69706998D1 (de)	2001-10-31	Heparin-beschichtete medizinische geräte zum intravenösen gebrauch, die heparin-bindende wachstumfaktor-konjugate enthalten
KR930009607A (ko)	1993-06-21	증식성 질환의 치료를 위한 다이피리다몰
ATE303107T1 (de)	2005-09-15	Endoluminale vaskuläre prothese
DE69532267D1 (de)	2004-01-22	Katheter für Stentimplantation
DE69826684D1 (de)	2004-11-04	Kovalent gebundenes n,o-carboxymethylchitosan und seine verwendungen
ATE278365T1 (de)	2004-10-15	Expandierbarer stent mit einem selbstexpandierbaren abschnitt
DE69841041D1 (de)	2009-09-17	Stent beschichtet mit dna
KR927003525A (ko)	1992-12-18	술폰아닐리드 유도체 및 의약
ES2054901T3 (es)	1994-08-16	Nuevos compuestos de n-ariltetrahidroftalimida.
BR0115882A (pt)	2003-12-02	Emprego de compostos de 1-fenil-3-dimetilaminopropano no tratamento da incontinência urinária
ES2175006T3 (es)	2002-11-16	N-(pirimidinil)-benzosulfonamidas como medicamentos.
FI952215L (fi)	1996-01-12	Istutettavia solumuovi PTFE-proteeseja, joilla on hyvä veri- ja kudosyhteensopivuus ja erinomainen aukipysyvyys
FR2811229B1 (fr)	2003-08-01	Utilisation d'un polysaccharide excrete par l'espece vibrio diabolicus en cicatrisation osseuse
ES2080855T3 (es)	1996-02-16	Pirido-oxacinas sustituidas.