ATE206161T1 - Cd 19 kodierende dna - Google Patents
Cd 19 kodierende dnaInfo
- Publication number
- ATE206161T1 ATE206161T1 AT96104493T AT96104493T ATE206161T1 AT E206161 T1 ATE206161 T1 AT E206161T1 AT 96104493 T AT96104493 T AT 96104493T AT 96104493 T AT96104493 T AT 96104493T AT E206161 T1 ATE206161 T1 AT E206161T1
- Authority
- AT
- Austria
- Prior art keywords
- coding dna
- cdna
- image
- host cell
- expression vector
- Prior art date
Links
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 239000002299 complementary DNA Substances 0.000 abstract 2
- 239000013604 expression vector Substances 0.000 abstract 2
- 238000012258 culturing Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Computational Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16041688A | 1988-02-25 | 1988-02-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE206161T1 true ATE206161T1 (de) | 2001-10-15 |
Family
ID=22576817
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89103127T ATE143690T1 (de) | 1988-02-25 | 1989-02-23 | Cd40 kodierende dna |
| AT96104493T ATE206161T1 (de) | 1988-02-25 | 1989-02-23 | Cd 19 kodierende dna |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89103127T ATE143690T1 (de) | 1988-02-25 | 1989-02-23 | Cd40 kodierende dna |
Country Status (6)
| Country | Link |
|---|---|
| EP (2) | EP0739980B1 (de) |
| AT (2) | ATE143690T1 (de) |
| DE (2) | DE68927277T2 (de) |
| ES (2) | ES2094113T3 (de) |
| HU (1) | HUT53672A (de) |
| WO (1) | WO1989008114A1 (de) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE321134T1 (de) | 1988-05-27 | 2006-04-15 | Applied Research Systems | Menschlicher fc-gamma-rezeptor iii |
| US5767077A (en) * | 1988-05-27 | 1998-06-16 | Applied Research Systems Ars Holding N.V. | Human Fc-γ receptor III |
| ES2097747T3 (es) * | 1989-03-09 | 1997-04-16 | Blood Res Center | Molecula de adhesion intercelular 2 y sus ligandos de union. |
| DE59010908D1 (de) * | 1989-09-12 | 2000-08-10 | Hoffmann La Roche | TNF-bindende Proteine |
| US5264554A (en) * | 1990-01-19 | 1993-11-23 | The Blood Center Of Southeastern Wisconsin, Inc. | Platelet cell adhesion molecule and variants thereof |
| US6641809B1 (en) * | 1990-03-26 | 2003-11-04 | Bristol-Myers Squibb Company | Method of regulating cellular processes mediated by B7 and CD28 |
| US5622853A (en) * | 1990-05-01 | 1997-04-22 | Becton Dickinson And Company | T lymphocyte precursor |
| CS156891A3 (en) * | 1990-06-01 | 1992-04-15 | Regeneron Pharma | Receptor of a cilary neurotropic factor |
| AU658370B2 (en) * | 1990-07-13 | 1995-04-13 | General Hospital Corporation, The | CD53 cell surface antigen and use thereof |
| DE4029227A1 (de) * | 1990-09-14 | 1992-03-19 | Imtox Gmbh | Arzneimittel enthaltend cd14 |
| US6071716A (en) * | 1990-10-01 | 2000-06-06 | Dana-Farber Cancer Institute | DNA encoding, B7, a new member of the IG superfamily with unique expression on activated and neoplastic B cells |
| US6238875B1 (en) * | 1991-03-12 | 2001-05-29 | The Scripps Research Institute | Diagnostic methods useful in the characterization of lymphoproliferative disease characterized by increased EPR-1 |
| US5367057A (en) | 1991-04-02 | 1994-11-22 | The Trustees Of Princeton University | Tyrosine kinase receptor flk-2 and fragments thereof |
| US5185438A (en) * | 1991-04-02 | 1993-02-09 | The Trustees Of Princeton University | Nucleic acids encoding hencatoporetic stem cell receptor flk-2 |
| CA2067031C (en) * | 1991-04-26 | 2003-02-18 | Shigekazu Nagata | Dna coding for human cell surface antigen |
| US5961974A (en) * | 1991-10-25 | 1999-10-05 | Immunex Corporation | Monoclonal antibodies to CD40 ligand, pharmaceutical composition comprising the same and hybridomas producing the same |
| US5962406A (en) * | 1991-10-25 | 1999-10-05 | Immunex Corporation | Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same |
| US5981724A (en) * | 1991-10-25 | 1999-11-09 | Immunex Corporation | DNA encoding CD40 ligand, a cytokine that binds CD40 |
| US7405270B2 (en) | 1991-10-25 | 2008-07-29 | Immunex Corporation | CD40-Ligand lacking native-pattern glycosylation |
| US5540926A (en) * | 1992-09-04 | 1996-07-30 | Bristol-Myers Squibb Company | Soluble and its use in B cell stimulation |
| AU6123894A (en) * | 1993-01-29 | 1994-08-15 | Board Of Trustees Of The Leland Stanford Junior University | Modulation of physiological responses of lymphocytes by cd38 or antibodies thereto |
| WO1995006750A1 (en) * | 1993-09-03 | 1995-03-09 | Cellpro, Incorporated | Methods for quantifying the number of cells containing a selected nucleic acid sequence in a heterogenous population of cells |
| IL111748A0 (en) * | 1993-12-03 | 1995-01-24 | Zeneca Ltd | Proteins |
| GB9404513D0 (en) * | 1994-03-09 | 1994-04-20 | Medical Res Council | Method of cloning |
| US5587299A (en) * | 1994-04-20 | 1996-12-24 | Memorial Sloan-Kettering Cancer Center | Isolated nucleic acid molecule coding for fibroblast activation protein alpha and uses thereof |
| ATE309267T1 (de) | 1994-04-28 | 2005-11-15 | Boehringer Ingelheim Pharma | Methode zur proliferation und differenzierung von b-zellen und verwendungen dafür |
| US5925557A (en) * | 1994-09-29 | 1999-07-20 | The Regents Of The University Of California | DNA encoding mitogen activated protein kinase, FRK |
| CA2223088A1 (en) | 1995-06-07 | 1996-12-19 | Bob Dale Brown | Novel carbamate-based cationic lipids |
| AU4825699A (en) * | 1998-06-19 | 2000-01-05 | Genzyme Corporation | Identification and use of differentially expressed genes and polynucleotide sequences |
| IL146005A0 (en) | 1999-05-07 | 2002-07-25 | Genentech Inc | Treatment of autoimmune diseases with antagonists which bind to b cell surface markers |
| ES2586850T3 (es) * | 1999-11-29 | 2016-10-19 | The Trustees Of Columbia University In The City Of New York | Aislamiento de cinco genes novedosos que codifican nuevos melanomas de tipo receptor de Fc implicados en la patogénesis del linfoma/melanoma |
| US7105149B1 (en) | 1999-11-29 | 2006-09-12 | The Trustees Of Columbia University In The City Of New York | Isolation of five novel genes coding for new Fc receptors-type melanoma involved in the pathogenesis of lymphoma/myeloma |
| EP1297123B1 (de) * | 2000-06-21 | 2007-06-06 | Novozymes A/S | Verfahren zum nachweis von genen von sekretierten proteinen |
| US7067252B2 (en) | 2000-06-21 | 2006-06-27 | Novozymes A/S | Method for genome mining for secreted protein genes |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| US20030133939A1 (en) | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
| HUE035898T2 (en) | 2002-12-16 | 2018-05-28 | Genentech Inc | Immunoglobulin variants and their applications |
| ME00426B (me) | 2003-04-09 | 2011-10-10 | Genentech Inc | Liječenje autoimunih bolesti kod pacijenata sa neadekvatnim odgovorom na tnf-alfa inhibitor |
| ES2537738T3 (es) | 2003-06-05 | 2015-06-11 | Genentech, Inc. | Terapia de combinación para trastornos de células B |
| JPWO2005075640A1 (ja) * | 2004-02-10 | 2008-01-10 | 学校法人日本大学 | イヌcd20遺伝子 |
| SG183012A1 (en) | 2004-06-04 | 2012-08-30 | Genentech Inc | Method for treating multiple sclerosis |
| EP2377555A3 (de) | 2004-11-18 | 2011-11-23 | Imclone LLC | Antikörper gegen den vaskulären endothelialen Wachstumsfaktorrezeptor-1 |
| EP2551282A3 (de) | 2005-03-23 | 2013-02-13 | Genmab A/S | Antikörper gegen CD38 zur Behandling von multiplem Myelom |
| US7601335B2 (en) | 2005-05-20 | 2009-10-13 | Genentech, Inc. | Pretreatment of a biological sample from an autoimmune disease subject |
| WO2007014238A2 (en) | 2005-07-25 | 2007-02-01 | Trubion Pharmaceuticals, Inc. | Single dose use of cd20-specific binding molecules |
| AU2006272555B2 (en) | 2005-07-25 | 2012-03-08 | Aptevo Research And Development Llc | B-cell reduction using CD37-specific and CD20-specific binding molecules |
| MY149159A (en) | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
| CN105837690A (zh) | 2006-06-12 | 2016-08-10 | 新兴产品开发西雅图有限公司 | 具有效应功能的单链多价结合蛋白 |
| PL2081595T3 (pl) | 2006-09-26 | 2019-11-29 | Genmab As | Anty-cd38 wraz z kortykosteroidami wraz ze środkiem chemioterapeutycznym niebędącym kortykosteroidem, do leczenia guzów nowotworowych |
| EP2586788B1 (de) | 2007-07-09 | 2017-11-29 | Genentech, Inc. | Verhindern der Disulfid-Bindungsreduktion während der rekombinanten Herstellung von Polypeptiden |
| DK2233149T3 (en) | 2007-10-16 | 2016-05-17 | Zymogenetics Inc | COMBINATION OF TRANSMEMBRANAKTIVATOR AND CALCIUM MODULATOR AND cyclophilin-LIGAND INTERAKTOR (TACI) AND ANTI-CD20 MEANS FOR TREATMENT OF AUTO-IMMUNE DISEASE |
| US7914785B2 (en) | 2008-01-02 | 2011-03-29 | Bergen Teknologieverforing As | B-cell depleting agents, like anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome |
| EP2077281A1 (de) | 2008-01-02 | 2009-07-08 | Bergen Teknologioverforing AS | Anti-CD20-Antikörper oder Fragmente davon zur Behandlung von chronischen Ermüdungssyndrom |
| NZ603059A (en) | 2008-04-11 | 2014-07-25 | Emergent Product Dev Seattle | Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof |
| AR073295A1 (es) | 2008-09-16 | 2010-10-28 | Genentech Inc | Metodos para tratar la esclerosis multiple progresiva. articulo de fabricacion. |
| WO2010075249A2 (en) | 2008-12-22 | 2010-07-01 | Genentech, Inc. | A method for treating rheumatoid arthritis with b-cell antagonists |
| MX355650B (es) | 2009-08-11 | 2018-04-26 | Genentech Inc | Produccion de proteinas en medios de cultivo de celulas libres de glutamina. |
| AR080154A1 (es) | 2010-02-10 | 2012-03-14 | Immunogen Inc | Anticuerpos cd20 y su utilizacion |
| JP6002659B2 (ja) | 2010-04-13 | 2016-10-05 | セルデックス・セラピューティクス・インコーポレイテッド | ヒトcd27に結合する抗体およびその使用 |
| EP2580243B1 (de) | 2010-06-09 | 2019-10-16 | Genmab A/S | Antikörper gegen menschliches cd38 |
| US9192664B2 (en) * | 2011-12-05 | 2015-11-24 | Immunomedics, Inc. | Therapeutic use of anti-CD22 antibodies for inducing trogocytosis |
| US9603927B2 (en) | 2014-02-28 | 2017-03-28 | Janssen Biotech, Inc. | Combination therapies with anti-CD38 antibodies |
| US9732154B2 (en) | 2014-02-28 | 2017-08-15 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia |
| WO2016040294A2 (en) | 2014-09-09 | 2016-03-17 | Janssen Biotech, Inc. | Combination therapies with anti-cd38 antibodies |
| PE20171094A1 (es) | 2014-12-04 | 2017-08-07 | Janssen Biotech Inc | Anticuerpos anti-cd38 para el tratamiento de la leucemia linfoblastica aguda |
| CR20170526A (es) | 2015-05-20 | 2018-04-03 | Janssen Biotech Inc | ANTICUERPOS ANTI-CD38 PARA EL TRATAMIENTO DE AMILOIDOSIS DE CADENA LIGERA y OTRAS ENFERMEDADES MALIGNAS HEMATOLÓGICAS POSITIVAS PARA CD38 |
| JP6518917B2 (ja) | 2015-05-29 | 2019-05-29 | アッヴィ・インコーポレイテッド | 抗cd40抗体およびその使用 |
| CN107708734B (zh) | 2015-06-22 | 2022-01-11 | 詹森生物科技公司 | 用抗cd38抗体和生存素抑制剂联合治疗血红素恶性肿瘤 |
| AU2016282334B2 (en) | 2015-06-24 | 2022-07-21 | F. Hoffmann-La Roche Ag | Anti-transferrin receptor antibodies with tailored affinity |
| US20170044265A1 (en) | 2015-06-24 | 2017-02-16 | Janssen Biotech, Inc. | Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38 |
| HK1251480A1 (zh) | 2015-09-21 | 2019-02-01 | Aptevo Research And Development Llc | Cd3结合多肽 |
| MX2018003822A (es) | 2015-10-02 | 2018-06-22 | Hoffmann La Roche | Anticuerpos biespecificos contra el cd20 humano y el receptor de transferrina humano y metodos de uso. |
| AR106189A1 (es) | 2015-10-02 | 2017-12-20 | Hoffmann La Roche | ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO |
| US10781261B2 (en) | 2015-11-03 | 2020-09-22 | Janssen Biotech, Inc. | Subcutaneous formulations of anti-CD38 antibodies and their uses |
| JP7027321B2 (ja) | 2015-11-03 | 2022-03-01 | ヤンセン バイオテツク,インコーポレーテツド | 抗cd38抗体の皮下製剤及びその使用 |
| WO2018002181A1 (en) | 2016-06-28 | 2018-01-04 | Umc Utrecht Holding B.V. | TREATMENT OF IgE-MEDIATED DISEASES WITH ANTIBODIES THAT SPECIFICALLY BIND CD38 |
| US11618787B2 (en) | 2017-10-31 | 2023-04-04 | Janssen Biotech, Inc. | Methods of treating high risk multiple myeloma |
| KR20210011919A (ko) | 2018-04-17 | 2021-02-02 | 셀덱스 쎄라퓨틱스, 인크. | 항-cd27 항체 및 항-pd-l1 항체 및 이중특이적 작제물 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5340921A (en) * | 1986-07-03 | 1994-08-23 | T Cell Sciences, Inc. | Γ, δT cell receptor and methods and detection |
-
1988
- 1988-08-16 WO PCT/US1988/002809 patent/WO1989008114A1/en not_active Ceased
- 1988-08-16 HU HU89958A patent/HUT53672A/hu unknown
-
1989
- 1989-02-23 DE DE68927277T patent/DE68927277T2/de not_active Expired - Lifetime
- 1989-02-23 EP EP96104493A patent/EP0739980B1/de not_active Expired - Lifetime
- 1989-02-23 ES ES89103127T patent/ES2094113T3/es not_active Expired - Lifetime
- 1989-02-23 AT AT89103127T patent/ATE143690T1/de not_active IP Right Cessation
- 1989-02-23 DE DE68929329T patent/DE68929329T2/de not_active Expired - Fee Related
- 1989-02-23 ES ES96104493T patent/ES2164794T3/es not_active Expired - Lifetime
- 1989-02-23 AT AT96104493T patent/ATE206161T1/de not_active IP Right Cessation
- 1989-02-23 EP EP89103127A patent/EP0330191B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE68929329D1 (de) | 2001-10-31 |
| WO1989008114A1 (en) | 1989-09-08 |
| ATE143690T1 (de) | 1996-10-15 |
| AU627710B2 (en) | 1992-09-03 |
| EP0330191A3 (de) | 1990-08-16 |
| DE68927277D1 (de) | 1996-11-07 |
| EP0739980A2 (de) | 1996-10-30 |
| EP0739980B1 (de) | 2001-09-26 |
| EP0739980A3 (de) | 1996-12-18 |
| EP0330191B1 (de) | 1996-10-02 |
| DE68929329T2 (de) | 2002-07-04 |
| ES2164794T3 (es) | 2002-03-01 |
| DE68927277T2 (de) | 1997-03-20 |
| HU890958D0 (en) | 1990-09-28 |
| HUT53672A (en) | 1990-11-28 |
| AU2947389A (en) | 1989-09-22 |
| EP0330191A2 (de) | 1989-08-30 |
| ES2094113T3 (es) | 1997-01-16 |
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