ATE206165T1 - Verfahren zur herstellung von l-leucin - Google Patents
Verfahren zur herstellung von l-leucinInfo
- Publication number
- ATE206165T1 ATE206165T1 AT95110188T AT95110188T ATE206165T1 AT E206165 T1 ATE206165 T1 AT E206165T1 AT 95110188 T AT95110188 T AT 95110188T AT 95110188 T AT95110188 T AT 95110188T AT E206165 T1 ATE206165 T1 AT E206165T1
- Authority
- AT
- Austria
- Prior art keywords
- leucine
- producing
- accumulate
- recovering
- culture
- Prior art date
Links
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 title abstract 9
- 238000004519 manufacturing process Methods 0.000 title 1
- 235000019454 L-leucine Nutrition 0.000 abstract 4
- 239000004395 L-leucine Substances 0.000 abstract 4
- 229960003136 leucine Drugs 0.000 abstract 4
- 241000588722 Escherichia Species 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 150000002614 leucines Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/848—Escherichia
- Y10S435/849—Escherichia coli
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14967994 | 1994-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE206165T1 true ATE206165T1 (de) | 2001-10-15 |
Family
ID=15480462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95110188T ATE206165T1 (de) | 1994-06-30 | 1995-06-29 | Verfahren zur herstellung von l-leucin |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5744331A (de) |
| EP (1) | EP0698668B1 (de) |
| CN (2) | CN1100146C (de) |
| AT (1) | ATE206165T1 (de) |
| CA (1) | CA2152885C (de) |
| DE (1) | DE69522876T2 (de) |
| DK (1) | DK0698668T3 (de) |
| ES (1) | ES2164125T3 (de) |
| HK (1) | HK1000715A1 (de) |
| PT (1) | PT698668E (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2140450C1 (ru) * | 1997-10-29 | 1999-10-27 | Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО "АГРИ") | Штамм бактерий escherichia coli продуцент l-лейцина (варианты) |
| RU2201454C2 (ru) | 1999-07-09 | 2003-03-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Мутантная альфа-изопропилмалат синтаза (ipms), днк, кодирующая мутантную ipms, способ получения штамма escherichia coli, способ получения l-лейцина |
| US6573083B1 (en) | 2000-08-24 | 2003-06-03 | Stanley Raider | Method of weight reduction in human beings |
| RU2243260C2 (ru) * | 2002-06-25 | 2004-12-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-лейцина (варианты), штамм escherichia coli 505/pacyc-tyr b - продуцент l-лейцина |
| JP2010041920A (ja) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| EP2098597A1 (de) | 2008-03-04 | 2009-09-09 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| NL1037147C2 (nl) * | 2009-07-23 | 2011-01-25 | Opus Trade B V | Samenstelling, werkwijze voor het produceren ervan en het gebruik ervan. |
| RU2012112651A (ru) | 2012-04-02 | 2013-10-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") | САМОИНДУЦИРУЕМАЯ ЭКСПРЕССИОННАЯ СИСТЕМА И ЕЕ ПРИМЕНЕНИЕ ДЛЯ ПОЛУЧЕНИЯ ПОЛЕЗНЫХ МЕТАБОЛИТОВ С ПОМОЩЬЮ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae |
| EP3608409A1 (de) | 2018-08-09 | 2020-02-12 | Evonik Operations GmbH | Verfahren zur herstellung von l-aminosäuren unter verwendung verbesserter stämme aus der familie der enterobacteriaceae |
| CN109504624A (zh) * | 2018-11-20 | 2019-03-22 | 广东肇庆星湖生物科技股份有限公司 | 一种亮氨酸生产菌株的筛选方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3865690A (en) * | 1969-11-06 | 1975-02-11 | Ajinomoto Kk | Fermentative production of L-leucine |
| JPS5653992B2 (de) | 1974-03-22 | 1981-12-22 | ||
| JPS5651989A (en) * | 1979-10-01 | 1981-05-09 | Ajinomoto Co Inc | Preparation of l-valine by fermentation method |
| JPS5672695A (en) * | 1979-11-15 | 1981-06-16 | Ajinomoto Co Inc | Preparation of l-leucine |
| JPS58220697A (ja) | 1982-06-15 | 1983-12-22 | Green Cross Corp:The | アンテイトロンビン−３の活性測定方法及びその方法を使用するキツト |
| US4421854A (en) * | 1982-06-16 | 1983-12-20 | W. R. Grace & Co. | Fermentative preparation of L-leucine |
| JPS5955194A (ja) * | 1982-09-22 | 1984-03-30 | Nippon Kayaku Co Ltd | Ｌ−ロイシンの製造法及びそのための微生物 |
| JP3006926B2 (ja) * | 1991-09-04 | 2000-02-07 | 協和醗酵工業株式会社 | 発酵法によるｌ−スレオニンの製造法 |
| JP3510331B2 (ja) * | 1994-06-30 | 2004-03-29 | 協和醗酵工業株式会社 | 発酵法によるｌ−アミノ酸の製造法 |
-
1995
- 1995-06-28 CA CA002152885A patent/CA2152885C/en not_active Expired - Lifetime
- 1995-06-29 ES ES95110188T patent/ES2164125T3/es not_active Expired - Lifetime
- 1995-06-29 CN CN95108174A patent/CN1100146C/zh not_active Expired - Lifetime
- 1995-06-29 DK DK95110188T patent/DK0698668T3/da active
- 1995-06-29 EP EP95110188A patent/EP0698668B1/de not_active Expired - Lifetime
- 1995-06-29 PT PT95110188T patent/PT698668E/pt unknown
- 1995-06-29 AT AT95110188T patent/ATE206165T1/de active
- 1995-06-29 US US08/496,788 patent/US5744331A/en not_active Expired - Lifetime
- 1995-06-29 DE DE69522876T patent/DE69522876T2/de not_active Expired - Lifetime
- 1995-06-29 CN CN02126475.9A patent/CN1246469C/zh not_active Expired - Lifetime
-
1997
- 1997-11-20 HK HK97102213A patent/HK1000715A1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1246469C (zh) | 2006-03-22 |
| PT698668E (pt) | 2002-02-28 |
| CN1127787A (zh) | 1996-07-31 |
| ES2164125T3 (es) | 2002-02-16 |
| CN1100146C (zh) | 2003-01-29 |
| DK0698668T3 (da) | 2001-12-03 |
| EP0698668A1 (de) | 1996-02-28 |
| EP0698668B1 (de) | 2001-09-26 |
| CA2152885C (en) | 2007-05-01 |
| US5744331A (en) | 1998-04-28 |
| DE69522876T2 (de) | 2002-04-11 |
| CN1448512A (zh) | 2003-10-15 |
| DE69522876D1 (de) | 2001-10-31 |
| CA2152885A1 (en) | 1995-12-31 |
| HK1000715A1 (en) | 2002-03-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |