ATE206211T1 - Linker-system zum aktivieren von oberflächen für die biokonjugation und verfahren zu ihrer verwendung - Google Patents

Linker-system zum aktivieren von oberflächen für die biokonjugation und verfahren zu ihrer verwendung

Info

Publication number
ATE206211T1
ATE206211T1 AT00110428T AT00110428T ATE206211T1 AT E206211 T1 ATE206211 T1 AT E206211T1 AT 00110428 T AT00110428 T AT 00110428T AT 00110428 T AT00110428 T AT 00110428T AT E206211 T1 ATE206211 T1 AT E206211T1
Authority
AT
Austria
Prior art keywords
linker system
bioconjugation
activating surfaces
linker
activating
Prior art date
Application number
AT00110428T
Other languages
English (en)
Inventor
Holger Klapproth
Original Assignee
Biochip Technologies Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochip Technologies Gmbh filed Critical Biochip Technologies Gmbh
Application granted granted Critical
Publication of ATE206211T1 publication Critical patent/ATE206211T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT00110428T 2000-05-16 2000-05-16 Linker-system zum aktivieren von oberflächen für die biokonjugation und verfahren zu ihrer verwendung ATE206211T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00110428A EP1132739B1 (de) 2000-05-16 2000-05-16 Linker-System zum Aktivieren von Oberflächen für die Biokonjugation und Verfahren zu ihrer Verwendung

Publications (1)

Publication Number Publication Date
ATE206211T1 true ATE206211T1 (de) 2001-10-15

Family

ID=8168735

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00110428T ATE206211T1 (de) 2000-05-16 2000-05-16 Linker-system zum aktivieren von oberflächen für die biokonjugation und verfahren zu ihrer verwendung

Country Status (11)

Country Link
US (1) US6921669B2 (de)
EP (1) EP1132739B1 (de)
JP (1) JP2003533697A (de)
AT (1) ATE206211T1 (de)
AU (1) AU7404201A (de)
CA (1) CA2375160A1 (de)
DE (1) DE60000014T2 (de)
DK (1) DK1132739T3 (de)
ES (1) ES2164632T3 (de)
PT (1) PT1132739E (de)
WO (1) WO2001088535A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2288760T3 (es) 1996-04-25 2008-01-16 Bioarray Solutions Ltd. Ensamblaje electrocinetico controlado por luz de particulas proximas a superficies.
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
EP1451318A4 (de) * 2001-10-12 2007-06-27 Perkinelmer Las Inc Zusammenstellungen von nukleinsäuren und arrays und verfahren zu ihrer verwendung
CA2497740C (en) 2001-10-15 2011-06-21 Bioarray Solutions, Ltd. Multiplexed analysis of polymorphic loci by probe elongation-mediated detection
US7335153B2 (en) 2001-12-28 2008-02-26 Bio Array Solutions Ltd. Arrays of microparticles and methods of preparation thereof
FR2840324B1 (fr) * 2002-05-28 2005-07-15 Europ Synchrotron Radiation Fa Fabrication de monocouches moleculaires organisees et substrat adapte
US7919653B2 (en) * 2002-07-30 2011-04-05 Reverse Proteomics Research Institute Co., Ltd. Method of inhibiting nonspecific interaction between molecules on solid phase support
WO2004047007A1 (en) 2002-11-15 2004-06-03 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
US7070922B2 (en) 2002-12-04 2006-07-04 International Business Machines Corporation Surface treatment
US20050059105A1 (en) * 2003-07-25 2005-03-17 Board Of Trustees Of Michigan State University Impedimetric biosensor and its use for rapid detection of bacterial pathogens in solution
JP4564959B2 (ja) 2003-09-22 2010-10-20 バイオアレイ ソリューションズ リミテッド 生体分子に共有結合できる、複数の官能基を持つ表面固定化高分子電解質
US7563569B2 (en) 2003-10-28 2009-07-21 Michael Seul Optimization of gene expression analysis using immobilized capture probes
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
JP2006194796A (ja) * 2005-01-14 2006-07-27 Kyushu Inoac Co Ltd 診断用容器
US20070055013A1 (en) * 2005-02-21 2007-03-08 Noriho Kamiya Substrate and method of immobilizing protein
HRP20141253T1 (en) 2006-05-05 2015-03-13 The Regents Of The Universitiy Of Michigan Intermediates for the preparation of bivalent smac mimetics
KR100819064B1 (ko) * 2006-12-19 2008-04-04 (재)대구경북과학기술연구원 생분자 고정화 링커
US20110108411A1 (en) * 2009-11-11 2011-05-12 Popik Vladimir V Methods for labeling a substrate using a hetero-diels-alder reaction
US9090542B2 (en) 2009-11-11 2015-07-28 University Of Georgia Research Foundation, Inc. Methods for labeling a substrate using a hetero-diels-alder reaction
US20150118728A1 (en) * 2012-04-20 2015-04-30 Agency For Science, Technology And Research Apparatus and method for separating a biological entity from a sample volume
US20150076049A1 (en) * 2012-04-20 2015-03-19 Agency For Science, Technology And Research Microfilter and apparatus for separating a biological entity from a sample volume
ES2740907T3 (es) 2014-10-03 2020-02-07 Synaffix Bv Enlazador de sulfamida, conjugados de los mismos y métodos de preparación
CN108883191B (zh) 2016-02-08 2022-10-14 西纳福克斯股份有限公司 用于靶向cd30肿瘤的具有改善的治疗指数的抗体-缀合物以及用于改善抗体-缀合物的治疗指数的方法
US10874746B2 (en) 2016-02-08 2020-12-29 Synaffix B.V. Sulfamide linkers for use in bioconjugates
EP3413915A1 (de) 2016-02-08 2018-12-19 Synaffix B.V. Antikörperkonjugate mit verbessertem therapeutischem index zur abzielung auf her2-tumoren und verfahren zur verbesserung des therapeutischen index von antikörperkonjugaten
US11951175B2 (en) 2016-02-08 2024-04-09 Synaffix B.V. Bioconjugates containing sulfamide linkers for use in treatment
WO2017137457A1 (en) 2016-02-08 2017-08-17 Synaffix B.V. Antibody-conjugates with improved therapeutic index for targeting cd30 tumours and method for improving therapeutic index of antibody-conjugates
WO2019185586A1 (en) 2018-03-26 2019-10-03 Universidad Complutense De Madrid Ligands for enhanced imaging and drug delivery to neuroblastoma cells

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707296B1 (fr) * 1993-07-09 1995-09-29 Genset Sa Procédé de synthèse d'acides nucléiques sur support solide et composés utiles notamment comme support solide dans ledit procédé.
JPH08220673A (ja) * 1995-02-17 1996-08-30 Konica Corp ハロゲン化銀写真乳剤及びハロゲン化銀写真要素及びその処理方法
JP4182269B2 (ja) * 1997-08-08 2008-11-19 ベーリングウエルケ、アクティエンゲゼルシャフト 生体分子のポリサッカライド接合体
AU9402198A (en) * 1997-09-26 1999-04-23 Becton Dickinson & Company Preparing conjugates using polyethylene glycol linkers
WO1999036571A2 (en) * 1998-01-13 1999-07-22 Biochip Technologies Gmbh Method for the detection or nucleic acid of nucleic acid sequences

Also Published As

Publication number Publication date
EP1132739B1 (de) 2001-09-26
WO2001088535A1 (en) 2001-11-22
DE60000014D1 (de) 2001-11-22
US20030022189A1 (en) 2003-01-30
CA2375160A1 (en) 2001-11-22
JP2003533697A (ja) 2003-11-11
US6921669B2 (en) 2005-07-26
DE60000014T2 (de) 2002-05-02
ES2164632T3 (es) 2002-03-01
AU7404201A (en) 2001-11-26
PT1132739E (pt) 2002-03-28
DK1132739T3 (da) 2002-01-28
EP1132739A1 (de) 2001-09-12

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee