ATE206932T1 - Formulierung von stabilisierter kationischen transfektionsmittel/nukleinsäuren partikeln - Google Patents
Formulierung von stabilisierter kationischen transfektionsmittel/nukleinsäuren partikelnInfo
- Publication number
- ATE206932T1 ATE206932T1 AT98906986T AT98906986T ATE206932T1 AT E206932 T1 ATE206932 T1 AT E206932T1 AT 98906986 T AT98906986 T AT 98906986T AT 98906986 T AT98906986 T AT 98906986T AT E206932 T1 ATE206932 T1 AT E206932T1
- Authority
- AT
- Austria
- Prior art keywords
- transfection agent
- formulation
- acid particles
- cationic transfection
- nuclic acid
- Prior art date
Links
- 239000003795 chemical substances by application Substances 0.000 title abstract 3
- 239000002245 particle Substances 0.000 title abstract 3
- 238000001890 transfection Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 230000002776 aggregation Effects 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 125000002091 cationic group Chemical group 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9701467A FR2759298B1 (fr) | 1997-02-10 | 1997-02-10 | Formulation de particules agent(s) de transfection cationique(s)/acides nucleiques stabilisees |
| PCT/FR1998/000222 WO1998034648A1 (fr) | 1997-02-10 | 1998-02-06 | Formulation de particules agent(s) de transfection cationique(s)/acides nucleiques stabilisees |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE206932T1 true ATE206932T1 (de) | 2001-11-15 |
Family
ID=9503492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98906986T ATE206932T1 (de) | 1997-02-10 | 1998-02-06 | Formulierung von stabilisierter kationischen transfektionsmittel/nukleinsäuren partikeln |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1007097B1 (de) |
| JP (1) | JP2001511171A (de) |
| KR (1) | KR20000070914A (de) |
| AT (1) | ATE206932T1 (de) |
| AU (1) | AU737720B2 (de) |
| BR (1) | BR9807563A (de) |
| CA (1) | CA2278665A1 (de) |
| CZ (1) | CZ282199A3 (de) |
| DE (1) | DE69802102T2 (de) |
| DK (1) | DK1007097T3 (de) |
| ES (1) | ES2166146T3 (de) |
| FR (1) | FR2759298B1 (de) |
| GR (1) | GR3036919T3 (de) |
| HU (1) | HUP0001720A3 (de) |
| IL (1) | IL130765A0 (de) |
| NO (1) | NO993825D0 (de) |
| PT (1) | PT1007097E (de) |
| SK (1) | SK282685B6 (de) |
| WO (1) | WO1998034648A1 (de) |
| ZA (1) | ZA981034B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6359054B1 (en) * | 1994-11-18 | 2002-03-19 | Supratek Pharma Inc. | Polynucleotide compositions for intramuscular administration |
| WO1999052858A2 (en) * | 1998-04-08 | 1999-10-21 | Celltech Therapeutics Limited | Lipids |
| AU747597B2 (en) * | 1998-07-20 | 2002-05-16 | Inex Pharmaceuticals Corporation | Liposomal encapsulated nucleic acid-complexes |
| AU2001241958A1 (en) * | 2000-03-03 | 2001-09-17 | Valentis, Inc. | Improved poloxamer and poloxamine compositions for nucleic acid delivery |
| GB0009201D0 (en) * | 2000-04-14 | 2000-05-31 | Univ Nottingham | Cationic polymer - Nucleic acid complexes and methods of making them |
| US20020091242A1 (en) | 2000-10-11 | 2002-07-11 | Michel Bessodes | Acid-sensitive compounds, their preparation and uses |
| CA2426582A1 (en) * | 2000-10-20 | 2002-08-08 | Valentis, Inc. | Gene delivery formulations and methods for treatment of ischemic conditions |
| EP1232758A1 (de) * | 2001-02-19 | 2002-08-21 | Aventis Pasteur | Polynukleotid-Formulierung für verbesserte intrazellulare Übertragung |
| JP2007527431A (ja) | 2004-03-03 | 2007-09-27 | ルバンス セラピュティックス | 局所的診断及び治療用の輸送のための組成物及び方法 |
| US9211248B2 (en) | 2004-03-03 | 2015-12-15 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| ZA200707352B (en) | 2005-03-03 | 2009-04-29 | Revance Therapeutics Inc | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| JP4653242B1 (ja) | 2010-02-12 | 2011-03-16 | ナノキャリア株式会社 | 粒子状医薬組成物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1181937A3 (de) * | 1994-08-09 | 2004-02-04 | Cytrx Corporation | Nukleinsäure enthaltender Impfstoff, Impfstoff-adjuvans |
| AU5527696A (en) * | 1995-03-31 | 1996-10-16 | Children's Hospital Medical Center | Use of surfactants for introducing genetic material into lun g cells |
| US6120794A (en) * | 1995-09-26 | 2000-09-19 | University Of Pittsburgh | Emulsion and micellar formulations for the delivery of biologically active substances to cells |
-
1997
- 1997-02-10 FR FR9701467A patent/FR2759298B1/fr not_active Expired - Fee Related
-
1998
- 1998-02-06 HU HU0001720A patent/HUP0001720A3/hu unknown
- 1998-02-06 IL IL13076598A patent/IL130765A0/xx unknown
- 1998-02-06 SK SK1082-99A patent/SK282685B6/sk unknown
- 1998-02-06 AT AT98906986T patent/ATE206932T1/de not_active IP Right Cessation
- 1998-02-06 EP EP98906986A patent/EP1007097B1/de not_active Expired - Lifetime
- 1998-02-06 CA CA002278665A patent/CA2278665A1/fr not_active Abandoned
- 1998-02-06 KR KR1019997007179A patent/KR20000070914A/ko not_active Ceased
- 1998-02-06 AU AU62987/98A patent/AU737720B2/en not_active Ceased
- 1998-02-06 WO PCT/FR1998/000222 patent/WO1998034648A1/fr not_active Ceased
- 1998-02-06 ES ES98906986T patent/ES2166146T3/es not_active Expired - Lifetime
- 1998-02-06 DK DK98906986T patent/DK1007097T3/da active
- 1998-02-06 CZ CZ992821A patent/CZ282199A3/cs unknown
- 1998-02-06 PT PT98906986T patent/PT1007097E/pt unknown
- 1998-02-06 DE DE69802102T patent/DE69802102T2/de not_active Expired - Lifetime
- 1998-02-06 JP JP53388198A patent/JP2001511171A/ja active Pending
- 1998-02-06 BR BR9807563-2A patent/BR9807563A/pt not_active IP Right Cessation
- 1998-02-09 ZA ZA981034A patent/ZA981034B/xx unknown
-
1999
- 1999-08-09 NO NO993825A patent/NO993825D0/no not_active Application Discontinuation
-
2001
- 2001-10-18 GR GR20010401473T patent/GR3036919T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2166146T3 (es) | 2002-04-01 |
| SK282685B6 (sk) | 2002-11-06 |
| HUP0001720A3 (en) | 2001-10-29 |
| AU737720B2 (en) | 2001-08-30 |
| NO993825L (no) | 1999-08-09 |
| BR9807563A (pt) | 2000-02-01 |
| EP1007097B1 (de) | 2001-10-17 |
| PT1007097E (pt) | 2002-04-29 |
| DE69802102D1 (de) | 2001-11-22 |
| DE69802102T2 (de) | 2002-03-14 |
| WO1998034648A1 (fr) | 1998-08-13 |
| AU6298798A (en) | 1998-08-26 |
| EP1007097A1 (de) | 2000-06-14 |
| CZ282199A3 (cs) | 1999-10-13 |
| JP2001511171A (ja) | 2001-08-07 |
| IL130765A0 (en) | 2001-01-28 |
| FR2759298B1 (fr) | 1999-04-09 |
| HUP0001720A1 (hu) | 2000-09-28 |
| NO993825D0 (no) | 1999-08-09 |
| ZA981034B (en) | 1998-08-11 |
| CA2278665A1 (fr) | 1998-08-13 |
| GR3036919T3 (en) | 2002-01-31 |
| FR2759298A1 (fr) | 1998-08-14 |
| KR20000070914A (ko) | 2000-11-25 |
| DK1007097T3 (da) | 2002-02-11 |
| SK108299A3 (en) | 2000-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |