ATE209029T1 - Liposomen, die materialien in partikelform enthalten - Google Patents

Liposomen, die materialien in partikelform enthalten

Info

Publication number
ATE209029T1
ATE209029T1 AT94928490T AT94928490T ATE209029T1 AT E209029 T1 ATE209029 T1 AT E209029T1 AT 94928490 T AT94928490 T AT 94928490T AT 94928490 T AT94928490 T AT 94928490T AT E209029 T1 ATE209029 T1 AT E209029T1
Authority
AT
Austria
Prior art keywords
liposomes
water insoluble
particulate
mum
materials
Prior art date
Application number
AT94928490T
Other languages
English (en)
Inventor
Gregory Gregoriadis
Sophia George Antimisiaris
Ihsan Gursel
Original Assignee
Secr Defence Brit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Secr Defence Brit filed Critical Secr Defence Brit
Application granted granted Critical
Publication of ATE209029T1 publication Critical patent/ATE209029T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277Preparation processes; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906Drug delivery
    • Y10S977/907Liposome
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/918Immunological

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT94928490T 1993-10-07 1994-10-07 Liposomen, die materialien in partikelform enthalten ATE209029T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939320668A GB9320668D0 (en) 1993-10-07 1993-10-07 Liposomes containing particulare materials
PCT/GB1994/002191 WO1995009610A1 (en) 1993-10-07 1994-10-07 Liposomes containing particulate materials

Publications (1)

Publication Number Publication Date
ATE209029T1 true ATE209029T1 (de) 2001-12-15

Family

ID=10743157

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94928490T ATE209029T1 (de) 1993-10-07 1994-10-07 Liposomen, die materialien in partikelform enthalten

Country Status (15)

Country Link
US (2) US6322809B1 (de)
EP (1) EP0722317B1 (de)
JP (1) JPH09503225A (de)
KR (1) KR100357804B1 (de)
CN (1) CN1108789C (de)
AT (1) ATE209029T1 (de)
AU (1) AU687893B2 (de)
BR (1) BR9407769A (de)
DE (1) DE69429186T2 (de)
DK (1) DK0722317T3 (de)
ES (1) ES2164714T3 (de)
GB (2) GB9320668D0 (de)
NZ (1) NZ274006A (de)
RU (1) RU2145212C1 (de)
WO (1) WO1995009610A1 (de)

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ATE535232T1 (de) * 1997-09-18 2011-12-15 Pacira Pharmaceuticals Inc Retardierte freisetzung liposomaler anesthetischer zusammensetzungen
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ES2325141T3 (es) 1998-07-17 2009-08-26 Pacira Pharmaceuticals, Inc. Composiciones biodegradables para la liberacion controlada de sustancias encapsuladas.
FR2802422B1 (fr) * 1999-12-21 2002-08-09 Capsulis Structures mixtes resultant de l'incorporation d'une macromolecule biologique, en particulier d'adn, dans une phase structuree d'amphiphiles et vesicules obtenues a partir de ces structures
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RU2191583C1 (ru) * 2001-03-28 2002-10-27 Лескова Галина Федоровна Способ коррекции геморрагического шока
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US20040005352A1 (en) * 2002-04-16 2004-01-08 Lopez Gabriel P. Biologically functionalized porous microspheres
RU2217129C1 (ru) * 2002-10-28 2003-11-27 Государственный научно-исследовательский институт особо чистых биопрепаратов Способ получения липосомальных препаратов
SE0300795D0 (sv) 2003-03-24 2003-03-24 Isconova Ab Composition comprising iscom particles and live micro-organisms
WO2005002546A1 (en) * 2003-06-27 2005-01-13 Smithkline Beecham Corporation Stabilized topotecan liposomal composition and methods
WO2007041627A1 (en) * 2005-10-03 2007-04-12 Pinsky Mark A Compositions and methods for improved skin care
FR2900576B1 (fr) * 2006-05-03 2008-09-19 Centre Nat Rech Scient Procede de concentration extemporanee et reversible de liposomes.
CN101605534A (zh) * 2006-10-06 2009-12-16 Scil技术股份有限公司 脊柱髓核植入物
US9456983B1 (en) 2006-12-08 2016-10-04 Advanced Cardiovascular Systems, Inc. Therapeutic composition with enhanced vessel targeting
US8372427B2 (en) * 2007-03-05 2013-02-12 Abbott Cardiovascular Systems Inc. Therapeutic composition with enhanced endothelium targeting
US9044385B2 (en) * 2007-05-16 2015-06-02 Abbott Cardiovascular Systems Inc. Therapeutic compositions for targeted vessel delivery
US20090047318A1 (en) 2007-08-16 2009-02-19 Abbott Cardiovascular Systems Inc. Nanoparticle-coated medical devices and formulations for treating vascular disease
US8709472B1 (en) 2007-11-13 2014-04-29 Abbott Cardiovascular Systems Inc. Bioactive agent-loaded heart-targeting nanoparticles
AU2008345068A1 (en) * 2007-12-26 2009-07-09 Mark A. Pinsky Collagen formulations for improved skin care
WO2010135714A2 (en) 2009-05-22 2010-11-25 The Methodist Hospital Research Institute Methods for modulating adipocyte expression using microrna compositions
WO2011123525A1 (en) * 2010-04-01 2011-10-06 The Regents Of The University Of California Forming an artificial cell with controlled membrane composition, asymmetry and contents
RU2567746C2 (ru) * 2010-05-28 2015-11-10 ДИАГОН Кфт. Способ двухфазного получения липосом и способы их применения при изготовлении диагностических реагентов
CN102240531B (zh) * 2011-03-21 2013-07-10 徐涵 一种植物细胞微球及其应用
EP2682106A1 (de) * 2012-07-03 2014-01-08 Phares Pharmaceutical Research N.V. Verfahren zum Auflösen biologisch aktiver Verbindungen
CA2943190A1 (en) * 2014-03-25 2015-10-01 The Government Of The United States Of America As Represented By The Secretary Of The Army Non-toxic adjuvant formulation comprising a monophosphoryl lipid a (mpla)-containing liposome composition and a saponin
RU2589822C2 (ru) * 2014-12-02 2016-07-10 Федеральное государственное бюджетное учреждение науки Институт ядерной физики им. Г.И. Будкера Сибирского отделения РАН (ИЯФ СО РАН) Способ доставки борсодержащих препаратов для бор-нейтронозахватной терапии
JP6316182B2 (ja) 2014-12-19 2018-04-25 富士フイルム株式会社 リポソームの製造方法及びリポソーム製造装置
US20170049701A1 (en) * 2015-08-05 2017-02-23 Steven M. Kushner Clustoidal multilamellar soy lecithin phospholipid structures for transdermal, transmucosal, or oral delivery, improved intestinal absorption, and improved bioavailability of nutrients
KR101687735B1 (ko) * 2015-09-18 2016-12-19 서울대학교 산학협력단 신규의 동결건조보조제 및 새로운 인지질 용해용 혼합용매를 이용한 리포좀 동결분체의 제조방법
KR102714709B1 (ko) 2015-11-02 2024-10-07 바이오아트라, 인코퍼레이티드 조건부 활성 폴리펩티드
CN105483076B (zh) * 2015-12-23 2019-01-25 中国科学院生物物理研究所 一种脂肪体的制备方法及其应用
EP3541815A4 (de) 2016-11-18 2020-07-15 Pacira Pharmaceuticals, Inc. Multivesikuläre liposomenformulierung mit zinkmeloxicamkomplex-mikropartikeln und verfahren zur herstellung davon
EP3415140A1 (de) * 2017-06-16 2018-12-19 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zur herstellung einer funktionellen synthetischen zelle in form eines gigantischen unilamellaren vesikels
US10849924B2 (en) 2017-09-26 2020-12-01 New York Medical College Compositions and methods for restoring endothelial glycocalyx
JP7157999B2 (ja) * 2018-05-07 2022-10-21 国立研究開発法人産業技術総合研究所 微生物を封入したベシクルを用いた微生物の培養方法
JP2023543527A (ja) 2020-09-16 2023-10-16 アビセーダ セラピューティクス,インコーポレイテッド シアル酸リガンド修飾治療薬
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12151024B2 (en) 2021-01-22 2024-11-26 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
GB2627096A (en) 2021-10-14 2024-08-14 Pacira Pharmaceuticals Inc Bupivacaine multivesicular liposome formulations and uses thereof
WO2023129737A1 (en) 2021-12-31 2023-07-06 Aviceda Therapeutics, Inc. Glycomimetic ligands
EP4694933A1 (de) 2023-04-14 2026-02-18 Aviceda Therapeutics, Inc. Polysialinsäure-polymer-konjugat und nanopartikel
US12280149B1 (en) 2024-05-20 2025-04-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12251472B1 (en) 2024-05-20 2025-03-18 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US12156940B1 (en) 2024-05-20 2024-12-03 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

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DE3374837D1 (en) * 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
US4532089A (en) 1984-01-14 1985-07-30 Northwestern University Method of preparing giant size liposomes
US4880635B1 (en) 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
EP0172007B1 (de) * 1984-08-10 1991-05-22 Syntex (U.S.A.) Inc. Stabile Liposome mit wasserlöslichen Arzneimitteln
JPS6150912A (ja) 1984-08-16 1986-03-13 Shionogi & Co Ltd リポソ−ム製剤の製造法
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JPS6176414A (ja) * 1984-09-21 1986-04-18 Shionogi & Co Ltd リポソーム製剤の製法
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Also Published As

Publication number Publication date
US20020041895A1 (en) 2002-04-11
GB9320668D0 (en) 1993-11-24
JPH09503225A (ja) 1997-03-31
WO1995009610A1 (en) 1995-04-13
DK0722317T3 (da) 2002-05-21
EP0722317A1 (de) 1996-07-24
CN1200668A (zh) 1998-12-02
GB2297907B (en) 1997-12-10
KR100357804B1 (ko) 2004-06-14
RU2145212C1 (ru) 2000-02-10
ES2164714T3 (es) 2002-03-01
CN1108789C (zh) 2003-05-21
GB2297907A (en) 1996-08-21
EP0722317B1 (de) 2001-11-21
AU687893B2 (en) 1998-03-05
AU7790794A (en) 1995-05-01
GB9607359D0 (en) 1996-07-03
US6451338B1 (en) 2002-09-17
US6322809B1 (en) 2001-11-27
NZ274006A (en) 1997-02-24
BR9407769A (pt) 1997-03-18
DE69429186D1 (de) 2002-01-03
DE69429186T2 (de) 2002-07-11

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