ATE209186T1 - Überbrückte azabicyclische derivate als substanz p antagonisten - Google Patents

Überbrückte azabicyclische derivate als substanz p antagonisten

Info

Publication number
ATE209186T1
ATE209186T1 AT93906038T AT93906038T ATE209186T1 AT E209186 T1 ATE209186 T1 AT E209186T1 AT 93906038 T AT93906038 T AT 93906038T AT 93906038 T AT93906038 T AT 93906038T AT E209186 T1 ATE209186 T1 AT E209186T1
Authority
AT
Austria
Prior art keywords
pct
pantagonists
substance
date nov
bridged
Prior art date
Application number
AT93906038T
Other languages
English (en)
Inventor
Manoj C Desai
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE209186T1 publication Critical patent/ATE209186T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT93906038T 1992-05-18 1993-02-23 Überbrückte azabicyclische derivate als substanz p antagonisten ATE209186T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88511092A 1992-05-18 1992-05-18
PCT/US1993/001429 WO1993023380A1 (en) 1992-05-18 1993-02-23 Bridged aza-bicyclic derivatives as substance p antagonists

Publications (1)

Publication Number Publication Date
ATE209186T1 true ATE209186T1 (de) 2001-12-15

Family

ID=25386157

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93906038T ATE209186T1 (de) 1992-05-18 1993-02-23 Überbrückte azabicyclische derivate als substanz p antagonisten

Country Status (11)

Country Link
US (1) US5498614A (de)
EP (1) EP0641328B1 (de)
JP (1) JP2757234B2 (de)
AT (1) ATE209186T1 (de)
CA (1) CA2134964C (de)
DE (1) DE69331190T2 (de)
DK (1) DK0641328T3 (de)
ES (1) ES2164657T3 (de)
FI (2) FI932229L (de)
PT (1) PT641328E (de)
WO (1) WO1993023380A1 (de)

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Also Published As

Publication number Publication date
FI106457B (fi) 2001-02-15
PT641328E (pt) 2002-04-29
JP2757234B2 (ja) 1998-05-25
WO1993023380A1 (en) 1993-11-25
DE69331190T2 (de) 2002-04-18
FI932229A7 (fi) 1993-11-19
EP0641328A1 (de) 1995-03-08
JPH07503483A (ja) 1995-04-13
CA2134964C (en) 1997-12-30
ES2164657T3 (es) 2002-03-01
FI932229A0 (fi) 1993-05-17
DE69331190D1 (de) 2002-01-03
US5498614A (en) 1996-03-12
CA2134964A1 (en) 1993-11-25
EP0641328B1 (de) 2001-11-21
FI932229L (fi) 1993-11-19
DK0641328T3 (da) 2002-05-21
FI20000085L (fi) 2000-01-17

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee