ES2065175T3 - Derivados de 1-azabiciclo(3.2.2)nonan-3-amina. - Google Patents

Derivados de 1-azabiciclo(3.2.2)nonan-3-amina.

Info

Publication number
ES2065175T3
ES2065175T3 ES92905882T ES92905882T ES2065175T3 ES 2065175 T3 ES2065175 T3 ES 2065175T3 ES 92905882 T ES92905882 T ES 92905882T ES 92905882 T ES92905882 T ES 92905882T ES 2065175 T3 ES2065175 T3 ES 2065175T3
Authority
ES
Spain
Prior art keywords
amina
derivatives
carbon
azabiciclo
nonan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92905882T
Other languages
English (en)
Inventor
John A Lowe Iii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PFIZER
Pfizer Inc
Original Assignee
PFIZER
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PFIZER, Pfizer Inc filed Critical PFIZER
Application granted granted Critical
Publication of ES2065175T3 publication Critical patent/ES2065175T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

EL PRESENTE INVENTO SE REFIERE A NUEVOS DERIVADOS DE AMINA R1, R2, R3, R4, R5 Y R6 SE SELECCIONAN CADA UNO INDEPENDIENTEMENTE DE HIDROGENO, FLUOR, CLORO, BROMO, TRIFLUOROMETIL, ALQUIL QUE TENGA DESDE UNO A TRES ATOMOS DE CARBONO, ALCOXI QUE TENGA DESDE UNO A TRES ATOMOS DE CARBONO, CARBOXI, ALCOXICARBONIL QUE TENGA DESDE UNO A TRES ATOMOS DE CARBONO EN LA PARTE ALCOXI, Y BENZOILOXICARBONIL. ESTOS COMPUESTOS SON UTILES EN EL TRATAMIENTO DE DESARREGLOS INFLAMATORIOS Y DEL SISTEMA NERVIOSO CENTRAL, ASI COMO EN OTROS DESARREGLOS.
ES92905882T 1991-03-01 1992-01-17 Derivados de 1-azabiciclo(3.2.2)nonan-3-amina. Expired - Lifetime ES2065175T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66323891A 1991-03-01 1991-03-01

Publications (1)

Publication Number Publication Date
ES2065175T3 true ES2065175T3 (es) 1995-02-01

Family

ID=24660986

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92905882T Expired - Lifetime ES2065175T3 (es) 1991-03-01 1992-01-17 Derivados de 1-azabiciclo(3.2.2)nonan-3-amina.

Country Status (12)

Country Link
US (1) US5373003A (es)
EP (1) EP0573522B1 (es)
JP (1) JPH082901B2 (es)
AT (1) ATE115581T1 (es)
CA (1) CA2105302C (es)
DE (1) DE69200921T2 (es)
DK (1) DK0573522T3 (es)
ES (1) ES2065175T3 (es)
FI (1) FI933803L (es)
IE (1) IE64743B1 (es)
PT (1) PT100178A (es)
WO (1) WO1992015585A1 (es)

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US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
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FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
TW458774B (en) 1995-10-20 2001-10-11 Pfizer Antiemetic pharmaceutical compositions
FR2741262B1 (fr) 1995-11-20 1999-03-05 Oreal Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
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Also Published As

Publication number Publication date
JPH082901B2 (ja) 1996-01-17
WO1992015585A1 (en) 1992-09-17
DE69200921D1 (de) 1995-01-26
FI933803A0 (fi) 1993-08-31
IE64743B1 (en) 1995-09-06
EP0573522B1 (en) 1994-12-14
DE69200921T2 (de) 1995-05-04
PT100178A (pt) 1993-05-31
IE920637A1 (en) 1992-09-09
DK0573522T3 (da) 1995-03-06
EP0573522A1 (en) 1993-12-15
CA2105302A1 (en) 1992-09-02
US5373003A (en) 1994-12-13
JPH06500123A (ja) 1994-01-06
CA2105302C (en) 1996-11-12
FI933803A7 (fi) 1993-08-31
FI933803L (fi) 1993-08-31
ATE115581T1 (de) 1994-12-15

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