ATE209639T1 - 7-o-ether von taxanderivaten - Google Patents

7-o-ether von taxanderivaten

Info

Publication number: ATE209639T1
Authority: AT; Austria
Prior art keywords: alkyl; substituted; alkyloxy; cycloalkyl; alkenyl
Prior art date: 1994-07-28

Application number

AT95111843T

Other languages

English (en)

Inventor

Henry S Wong

Mark D Wittman

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-07-28

Filing date

1995-07-27

Publication date

2001-12-15

1995-07-27 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2001-12-15 Application granted granted Critical

2001-12-15 Publication of ATE209639T1 publication Critical patent/ATE209639T1/de

Links

125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 4
125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 2
125000004648 C2-C8 alkenyl group Chemical group 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000004649 C2-C8 alkynyl group Chemical group 0.000 abstract 1
125000003302 alkenyloxy group Chemical group 0.000 abstract 1
125000003282 alkyl amino group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000005133 alkynyloxy group Chemical group 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000003107 substituted aryl group Chemical group 0.000 abstract 1
DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Medicines Containing Plant Substances (AREA)

AT95111843T 1994-07-28 1995-07-27 7-o-ether von taxanderivaten ATE209639T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/282,129 US6201140B1 (en)	1994-07-28	1994-07-28	7-0-ethers of taxane derivatives

Publications (1)

Publication Number	Publication Date
ATE209639T1 true ATE209639T1 (de)	2001-12-15

Family

ID=23080227

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95111843T ATE209639T1 (de)	1994-07-28	1995-07-27	7-o-ether von taxanderivaten

Country Status (10)

Country	Link
US (1)	US6201140B1 (de)
EP (1)	EP0694539B1 (de)
JP (1)	JPH08239373A (de)
AT (1)	ATE209639T1 (de)
AU (1)	AU688916B2 (de)
CA (1)	CA2152771C (de)
DE (1)	DE69524154T2 (de)
DK (1)	DK0694539T3 (de)
ES (1)	ES2167388T3 (de)
PT (1)	PT694539E (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2698871B1 (fr)	1992-12-09	1995-02-24	Rhone Poulenc Rorer Sa	Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US6040466A (en) *	1996-03-25	2000-03-21	Rhone Poulenc Rorer Sa	Taxoids, their preparation and pharmaceutical compositions containing them
US6232477B1 (en)	1996-03-25	2001-05-15	Aventis Pharma S.A.	Methods of preparing new taxoids and pharmaceutical compositions containing them
US6593482B2 (en)	1993-02-01	2003-07-15	Aventis Pharma S.A.	Methods for preparing new taxoids and pharmaceutical compositions containing them
US5847170A (en) *	1995-03-27	1998-12-08	Rhone-Poulenc Rorer, S.A.	Taxoids, their preparation and pharmaceutical compositions containing them
US6372780B2 (en)	1995-03-27	2002-04-16	Aventis Pharma S.A.	Methods of treating cell lines expressing multidrug resistance P-glycoprotein
MA23823A1 (fr)	1995-03-27	1996-10-01	Aventis Pharma Sa	Nouveaux taxoides, leur preparation et les compositions qui les contiennent
FR2745814B1 (fr) *	1996-03-06	1998-04-03	Rhone Poulenc Rorer Sa	Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
US5902822A (en) *	1997-02-28	1999-05-11	Bristol-Myers Squibb Company	7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels
EP0933360A1 (de)	1997-12-22	1999-08-04	Pharmachemie B.V.	Synthese von Beta-lactamen
US6156789A (en) *	1998-03-17	2000-12-05	Rhone-Poulenc Rorer S.A.	Method for treating abnormal cell proliferation in the brain
AU2003291458A1 (en) *	2002-11-08	2004-06-03	Bristol-Myers Squibb Company	Pharmaceutical compositions and methods of using taxane derivatives
WO2004043375A2 (en) *	2002-11-08	2004-05-27	Bristol-Myers Squibb Company	Pharmaceutical compositions and methods of using taxane derivatives
CN102775435B (zh) *	2012-08-21	2015-04-08	江苏红豆杉生物科技股份有限公司	一种用于制备7,10-甲氧基多西他赛的中间体的合成方法
CN102786502B (zh) *	2012-08-21	2014-05-14	江苏红豆杉生物科技有限公司	一种紫杉烷药物7,10-甲氧基多西他赛的合成方法
CN104086514A (zh) *	2014-06-19	2014-10-08	上海应用技术学院	紫杉醇衍生物及其制备方法
CN113698369A (zh) *	2021-08-31	2021-11-26	无锡紫杉药业有限公司	一种除去卡巴他赛中特定单杂的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2601675B1 (fr)	1986-07-17	1988-09-23	Rhone Poulenc Sante	Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US4814870A (en)	1987-08-05	1989-03-21	Compix Incorporated	Portable infrared imaging apparatus
US4960790A (en)	1989-03-09	1990-10-02	University Of Kansas	Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
US5175315A (en)	1989-05-31	1992-12-29	Florida State University	Method for preparation of taxol using β-lactam
US5229526A (en) *	1991-09-23	1993-07-20	Florida State University	Metal alkoxides
EP0884314B1 (de)	1991-09-23	2004-01-21	Florida State University	Metallalkoxide
US5250683A (en)	1991-09-23	1993-10-05	Florida State University	Certain substituted taxanes and pharmaceutical compositions containing them
US5227400A (en)	1991-09-23	1993-07-13	Florida State University	Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US5243045A (en)	1991-09-23	1993-09-07	Florida State University	Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
PT1001036E (pt)	1992-01-15	2005-01-31	Squibb & Sons Inc	Processos enzimaticos para o desdobramento de misturas enantiomericas de compostos uteis como intermediarios na preparacao de taxanos
US5272171A (en)	1992-02-13	1993-12-21	Bristol-Myers Squibb Company	Phosphonooxy and carbonate derivatives of taxol
CA2100808A1 (en)	1992-10-01	1994-04-02	Vittorio Farina	Deoxy paclitaxels
CA2111527C (en)	1992-12-24	2000-07-18	Jerzy Golik	Phosphonooxymethyl ethers of taxane derivatives
US9217093B1 (en)	2014-05-30	2015-12-22	Xerox Corporation	Palladium ink compositions

1994
- 1994-07-28 US US08/282,129 patent/US6201140B1/en not_active Expired - Fee Related
1995
- 1995-06-27 CA CA002152771A patent/CA2152771C/en not_active Expired - Fee Related
- 1995-07-25 JP JP7240402A patent/JPH08239373A/ja active Pending
- 1995-07-27 ES ES95111843T patent/ES2167388T3/es not_active Expired - Lifetime
- 1995-07-27 AU AU27215/95A patent/AU688916B2/en not_active Ceased
- 1995-07-27 EP EP95111843A patent/EP0694539B1/de not_active Expired - Lifetime
- 1995-07-27 DE DE69524154T patent/DE69524154T2/de not_active Expired - Fee Related
- 1995-07-27 PT PT95111843T patent/PT694539E/pt unknown
- 1995-07-27 AT AT95111843T patent/ATE209639T1/de not_active IP Right Cessation
- 1995-07-27 DK DK95111843T patent/DK0694539T3/da active

Also Published As

Publication number	Publication date
EP0694539B1 (de)	2001-11-28
AU688916B2 (en)	1998-03-19
CA2152771C (en)	2005-10-04
DE69524154T2 (de)	2002-07-18
CA2152771A1 (en)	1996-01-29
DE69524154D1 (de)	2002-01-10
PT694539E (pt)	2002-05-31
EP0694539A1 (de)	1996-01-31
AU2721595A (en)	1996-02-08
US6201140B1 (en)	2001-03-13
DK0694539T3 (da)	2002-03-18
JPH08239373A (ja)	1996-09-17
ES2167388T3 (es)	2002-05-16

Legal Events

Date	Code	Title	Description
2002-05-15	UEP	Publication of translation of european patent specification
2007-04-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE209639T1 (de)	2001-12-15	7-o-ether von taxanderivaten
FI875502A0 (fi)	1987-12-15	Morfolinoetylester av mykofenolsyra och dess derivat
MY129970A (en)	2007-05-31	Hypolipidaemic compounds
PT88603A (pt)	1988-10-01	Immunomodulatory azapiranes
PT747374E (pt)	2002-05-31	Benzopiranos substituidos com sulfonamido activadores dos canais do potassio
TW252918B (de)	1995-08-01
ATE205469T1 (de)	2001-09-15	Phenylbenzoesäureester-derivate und flüssigkristallzubereitungen
ATE86866T1 (de)	1993-04-15	Antikrebs-zusammensetzung.
CA2026778A1 (en)	1990-08-07	Dioxaphosphorinane compounds and polyolefin compositions stabilized therewith
DK183789D0 (da)	1989-04-17	2-alkyl-3-benzoylbenzofuraner og laegemidler indeholdende disse
IL90724A0 (en)	1990-01-18	Novel esters and pharmaceutical compositions containing same
NO904187D0 (no)	1990-09-26	Benzanilider.
DK0390138T3 (da)	1994-02-14	Platinkomplekser og antitumormidler med indhold deraf som aktiv bestanddel
GR3005900T3 (de)	1993-06-07
ES2019633B3 (es)	1991-07-01	Compuestos de azaantraceno.