ATE209903T1 - Verfahren i - Google Patents

Verfahren i

Info

Publication number
ATE209903T1
ATE209903T1 AT94929076T AT94929076T ATE209903T1 AT E209903 T1 ATE209903 T1 AT E209903T1 AT 94929076 T AT94929076 T AT 94929076T AT 94929076 T AT94929076 T AT 94929076T AT E209903 T1 ATE209903 T1 AT E209903T1
Authority
AT
Austria
Prior art keywords
agglomerates
procedure
spheronizing
spheronization
agglomerating
Prior art date
Application number
AT94929076T
Other languages
English (en)
Inventor
Eva Trofast
Johan Falk
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9303214A external-priority patent/SE9303214D0/xx
Priority claimed from SE9304271A external-priority patent/SE9304271D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE209903T1 publication Critical patent/ATE209903T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Control Of Multiple Motors (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Stereophonic System (AREA)
  • Exchange Systems With Centralized Control (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
  • Glanulating (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
AT94929076T 1993-10-01 1994-09-29 Verfahren i ATE209903T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9303214A SE9303214D0 (sv) 1993-10-01 1993-10-01 Process I
SE9304271A SE9304271D0 (sv) 1993-12-22 1993-12-22 Process I
PCT/SE1994/000896 WO1995009615A1 (en) 1993-10-01 1994-09-29 Process i
US08/317,033 US5551489A (en) 1993-10-01 1994-10-03 Agglomeration of finely divided powders

Publications (1)

Publication Number Publication Date
ATE209903T1 true ATE209903T1 (de) 2001-12-15

Family

ID=27355730

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94929076T ATE209903T1 (de) 1993-10-01 1994-09-29 Verfahren i

Country Status (23)

Country Link
US (1) US5551489A (de)
EP (1) EP0721331B1 (de)
JP (1) JP3732508B2 (de)
CN (1) CN1110300C (de)
AT (1) ATE209903T1 (de)
AU (1) AU679789B2 (de)
BR (1) BR9407686A (de)
CZ (1) CZ289214B6 (de)
DE (1) DE69429357T2 (de)
DK (1) DK0721331T3 (de)
EG (1) EG20677A (de)
ES (1) ES2166786T3 (de)
FI (1) FI116364B (de)
HU (1) HU222355B1 (de)
IL (1) IL111080A (de)
NO (1) NO314836B1 (de)
NZ (1) NZ274277A (de)
PL (1) PL175564B1 (de)
PT (1) PT721331E (de)
RU (1) RU2170082C2 (de)
SG (1) SG48049A1 (de)
SK (1) SK283569B6 (de)
WO (1) WO1995009615A1 (de)

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US6182712B1 (en) 1997-07-21 2001-02-06 Inhale Therapeutic Systems Power filling apparatus and methods for their use
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HRP20192334T1 (hr) 2014-09-17 2020-03-20 Oncodesign S.A. Makrociklički inhibitori kinaze rip2
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EP3634407A1 (de) 2017-05-11 2020-04-15 Remynd N.V. Inhibitoren von pde6delta zur verwendung bei der vorbeugung und/oder behandlung von epilepsie und/oder neurodegenerativen erkrankungen
DK3621963T3 (da) 2017-05-11 2024-04-15 Remynd N V Forbindelser til behandling af epilepsi, neurodegenerative lidelser og andre CNS-lidelser
CA3135420A1 (en) 2018-04-05 2019-10-10 Universiteit Hasselt Selective pde4d inhibitors against demyelinating diseases
US12281308B2 (en) 2018-08-29 2025-04-22 University Of Massachusetts Inhibition of protein kinases to treat Friedreich ataxia
CN114206864B (zh) 2019-05-14 2024-05-24 苏州四体康宸医药科技有限公司 喹唑啉-2.4-二酮衍生物作为parp抑制剂
WO2022157381A1 (en) 2021-01-25 2022-07-28 Universiteit Hasselt Phloretin for use in the treatment of neurodegenerative and demyelinating diseases
EP4387629A1 (de) 2021-08-18 2024-06-26 Katholieke Universiteit Leuven KU Leuven Research & Development 6-substituierte und 6,7-disubstituierte 7-deazapurin-ribonukleosidanaloga
EP4405357A1 (de) 2021-09-23 2024-07-31 Katholieke Universiteit Leuven KU Leuven Research & Development Ribonukleosidanaloga gegen -sars-cov-2
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Also Published As

Publication number Publication date
PT721331E (pt) 2002-05-31
JPH09504224A (ja) 1997-04-28
HUT74519A (en) 1997-01-28
NO314836B1 (no) 2003-06-02
DE69429357T2 (de) 2002-08-14
IL111080A0 (en) 1994-11-28
HU222355B1 (hu) 2003-06-28
SK39196A3 (en) 1997-06-04
FI961430A0 (fi) 1996-03-29
FI961430L (fi) 1996-03-29
PL313765A1 (en) 1996-07-22
EP0721331A1 (de) 1996-07-17
CN1110300C (zh) 2003-06-04
AU7826194A (en) 1995-05-01
IL111080A (en) 1999-08-17
DE69429357D1 (de) 2002-01-17
CZ94296A3 (en) 1996-06-12
NO961290D0 (no) 1996-03-29
HU9600821D0 (en) 1996-05-28
NO961290L (no) 1996-03-29
PL175564B1 (pl) 1999-01-29
CZ289214B6 (cs) 2001-12-12
AU679789B2 (en) 1997-07-10
FI116364B (fi) 2005-11-15
DK0721331T3 (da) 2002-02-11
US5551489A (en) 1996-09-03
BR9407686A (pt) 1997-02-04
NZ274277A (en) 1998-01-26
JP3732508B2 (ja) 2006-01-05
SG48049A1 (en) 1998-04-17
RU2170082C2 (ru) 2001-07-10
SK283569B6 (sk) 2003-09-11
ES2166786T3 (es) 2002-05-01
EP0721331B1 (de) 2001-12-05
WO1995009615A1 (en) 1995-04-13
CN1132476A (zh) 1996-10-02
EG20677A (en) 1999-11-30

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