ATE210187T1 - Eine familie von map2 proteinkinasen - Google Patents

Eine familie von map2 proteinkinasen

Info

Publication number
ATE210187T1
ATE210187T1 AT91912876T AT91912876T ATE210187T1 AT E210187 T1 ATE210187 T1 AT E210187T1 AT 91912876 T AT91912876 T AT 91912876T AT 91912876 T AT91912876 T AT 91912876T AT E210187 T1 ATE210187 T1 AT E210187T1
Authority
AT
Austria
Prior art keywords
map2
factor activity
family
methods
kinase
Prior art date
Application number
AT91912876T
Other languages
English (en)
Inventor
Teri G Boulton
Melanie H Cobb
George D Yancopoulos
Steven Nye
Nikos Panayotatos
Original Assignee
Regeneron Pharma
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma, Univ Texas filed Critical Regeneron Pharma
Application granted granted Critical
Publication of ATE210187T1 publication Critical patent/ATE210187T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT91912876T 1990-06-01 1991-06-03 Eine familie von map2 proteinkinasen ATE210187T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53200490A 1990-06-01 1990-06-01
US70154491A 1991-05-16 1991-05-16
PCT/US1991/003894 WO1991019008A1 (en) 1990-06-01 1991-06-03 A family of map2 protein kinases

Publications (1)

Publication Number Publication Date
ATE210187T1 true ATE210187T1 (de) 2001-12-15

Family

ID=27063710

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91912876T ATE210187T1 (de) 1990-06-01 1991-06-03 Eine familie von map2 proteinkinasen

Country Status (8)

Country Link
US (7) US5595904A (de)
EP (1) EP0651809B1 (de)
JP (1) JP3310283B2 (de)
AT (1) ATE210187T1 (de)
CA (1) CA2084076C (de)
DE (1) DE69132852T2 (de)
IE (1) IE911869A1 (de)
WO (1) WO1991019008A1 (de)

Families Citing this family (40)

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Publication number Priority date Publication date Assignee Title
WO1993011231A1 (en) * 1991-12-06 1993-06-10 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Tools for the diagnosis and treatment of alzheimer's disease
US5459036A (en) 1993-03-19 1995-10-17 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Extracellular signal-regulated kinase, sequences, and methods of production and use
US6361773B1 (en) * 1993-09-17 2002-03-26 Smithkline Beecham Corporation Antibodies produced against cytokine suppressive anti-inflammatory drug binding proteins
WO1996000233A1 (en) * 1994-06-24 1996-01-04 Children's Hospital And Medical Center Escherichia coli o157:h7 epithelial adhesin
NZ296748A (en) 1994-11-02 1999-11-29 Univ New York State Res Found Peripheral nervous system specific sodium channel proteins, DNA coding therefor, compositions and methods
WO1996027015A2 (en) * 1995-02-28 1996-09-06 Pharmacia & Upjohn Company A novel gene for a protein kinase associated with drug resistance
GB9525702D0 (en) * 1995-12-15 1996-02-14 Ciba Geigy Ag Process for activating a kinase
GB9525703D0 (en) * 1995-12-15 1996-02-14 Ciba Geigy Ag Screening method
DK1555320T3 (da) * 1996-08-16 2008-09-29 Genencor Int Ekspressionssystem, der stammer fra lipasereguleringskaskaden i Pseudomonas alcaligenes
US6376214B1 (en) 1997-02-18 2002-04-23 Smithkline Beecham Corporation DNA encoding a novel homolog of CSBP/p38 MAP kinase
AU6472998A (en) 1997-03-28 1998-10-22 Research Foundation Of The State University Of New York, The Antisense oligonucleotides for mitogen-activated protein kinases as therapy for breast cancer
US6007991A (en) * 1997-03-28 1999-12-28 The Research Foundation Of Suny Antisense oligonucleotides for mitogen-activated protein kinases as therapy for cancer
KR100218581B1 (ko) * 1997-04-08 1999-09-01 구자홍 액정표시장치를 가지는 휴대용 컴퓨터
AU7019498A (en) 1997-04-10 1998-10-30 Diagnocure Inc. Pca3, pca3 genes, and methods of use
US6114514A (en) * 1997-12-24 2000-09-05 Council Of Scientific & Industrial Research Mycobacterium tuberculosis specific DNA fragment
US6897019B1 (en) * 1998-04-17 2005-05-24 Tufts College Methods for treating and preventing insulin resistance and related disorders
US6501641B1 (en) * 1998-10-23 2002-12-31 Lg. Philips Lcd Co. Ltd. Portable computer having a flat panel display device
KR100508003B1 (ko) * 1998-11-11 2005-11-21 엘지.필립스 엘시디 주식회사 휴대용컴퓨터와그평판표시장치의결합방법
WO2001000677A1 (en) 1999-06-28 2001-01-04 The University Of Newcastle Research Associates Limited A method of modulating integrin mediated cellular activity and agents useful for same
ES2260059T3 (es) 1999-09-29 2006-11-01 Diagnocure Inc. Rna mensajero del pca3 en tejidos benignos y malignos de prostata.
AUPR230500A0 (en) 2000-12-22 2001-01-25 University Of Newcastle Research Associates Limited, The A method of modulating map kinase mediated cellular activity and agents useful in same
GB0102480D0 (en) * 2001-01-31 2001-03-14 Cyclacel Ltd Marker
US7816003B1 (en) 2001-12-19 2010-10-19 Arrowhead Coating and Converting, Inc. Adhesive film composition
EP1664337A4 (de) * 2002-10-23 2006-12-20 Exelixis Inc MBMs ALS MODIFIKATOREN VON VERZWEIGUNGSMORPHOGENESE SOWIE VERWENDUNGSVERFAHREN
AU2004209578A1 (en) 2003-02-07 2004-08-19 Diagnocure Inc. Method to detect prostate cancer in a sample
WO2005037308A1 (en) 2003-10-17 2005-04-28 Inter-K Pty Limited Methods and agents for the treatment of cancer
US7217428B2 (en) * 2004-05-28 2007-05-15 Technology Innovations Llc Drug delivery apparatus utilizing cantilever
CA2491067A1 (en) 2004-12-24 2006-06-24 Stichting Katholieke Universiteit Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer
US8978234B2 (en) 2011-12-07 2015-03-17 MoMelan Technologies, Inc. Methods of manufacturing devices for generating skin grafts
US9597111B2 (en) 2010-08-06 2017-03-21 Kci Licensing, Inc. Methods for applying a skin graft
US9610093B2 (en) 2010-08-06 2017-04-04 Kci Licensing, Inc. Microblister skin grafting
EP2967627B1 (de) 2013-03-14 2017-08-30 KCI Licensing, Inc. Saugfähige substrate zur entnahme von hauttransplantaten
US8935895B2 (en) 2013-03-15 2015-01-20 Quality Edge, Inc. Rollable ridge vent panel
EP3089681B1 (de) 2013-12-31 2021-09-08 3M Innovative Properties Company Flüssigkeitsunterstützte entnahme eines hautimplantats
WO2015103043A1 (en) 2013-12-31 2015-07-09 Kci Licensing, Inc. Sensor systems for skin graft harvesting
WO2016164890A1 (en) 2015-04-09 2016-10-13 Kci Licensing, Inc. Soft-tack, porous substrates for harvesting skin grafts
US11006974B2 (en) 2015-11-03 2021-05-18 Kci Licensing, Inc. Devices for creating an epidermal graft sheet
EP3658172A4 (de) 2017-07-25 2021-05-05 TrueBinding, Inc. Behandlung von krebs durch blockierung der interaktion von tim-3 und seinem liganden
CN113711036B (zh) 2019-01-30 2025-03-18 真和制药有限公司 抗gal3抗体及其用途
CN116157151A (zh) 2020-05-26 2023-05-23 真和制药有限公司 通过阻断半乳凝素-3治疗炎性疾病的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599305A (en) * 1984-07-16 1986-07-08 The Regents Of The University Of California Method and composition for detection of human chronic myelogenous leukemia
US5989894A (en) * 1990-04-20 1999-11-23 University Of Wyoming Isolated DNA coding for spider silk protein, a replicable vector and a transformed cell containing the DNA

Also Published As

Publication number Publication date
CA2084076A1 (en) 1991-12-02
US5914261A (en) 1999-06-22
US5872006A (en) 1999-02-16
US5595904A (en) 1997-01-21
DE69132852T2 (de) 2002-08-08
CA2084076C (en) 2004-11-23
EP0651809A1 (de) 1995-05-10
WO1991019008A1 (en) 1991-12-12
DE69132852D1 (de) 2002-01-17
IE911869A1 (en) 1991-12-04
JP3310283B2 (ja) 2002-08-05
US5776751A (en) 1998-07-07
JPH06501839A (ja) 1994-03-03
US6277963B1 (en) 2001-08-21
EP0651809A4 (de) 1993-08-25
US6303358B1 (en) 2001-10-16
EP0651809B1 (de) 2001-12-05
US6297035B1 (en) 2001-10-02

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