ATE210468T1 - Radioaktives kupferkomplex von dithiosemicarbazonederivate oder diaminediolschiffbasederivate - Google Patents

Radioaktives kupferkomplex von dithiosemicarbazonederivate oder diaminediolschiffbasederivate

Info

Publication number: ATE210468T1
Authority: AT; Austria
Prior art keywords: derivatives; copper complex; dithiosemicarbazone; radioactive copper; diaminediol
Prior art date: 1995-01-09

Application number

AT96300127T

Other languages

English (en)

Inventor

Yasuhisa Fujibayashi

Akira Yokoyama

Original Assignee

Nihon Mediphysics Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-01-09

Filing date

1996-01-08

Publication date

2001-12-15

1996-01-08 Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd

2001-12-15 Application granted granted Critical

2001-12-15 Publication of ATE210468T1 publication Critical patent/ATE210468T1/de

Links

150000004699 copper complex Chemical class 0.000 title abstract 3
230000002285 radioactive effect Effects 0.000 title abstract 3
206010021143 Hypoxia Diseases 0.000 abstract 2
229940039227 diagnostic agent Drugs 0.000 abstract 2
239000000032 diagnostic agent Substances 0.000 abstract 2
239000002262 Schiff base Substances 0.000 abstract 1
-1 diamine diol schiff base Chemical class 0.000 abstract 1
239000003085 diluting agent Substances 0.000 abstract 1
230000008034 disappearance Effects 0.000 abstract 1
230000007954 hypoxia Effects 0.000 abstract 1
230000001146 hypoxic effect Effects 0.000 abstract 1
230000004065 mitochondrial dysfunction Effects 0.000 abstract 1
238000006722 reduction reaction Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Optics & Photonics (AREA)
Pharmacology & Pharmacy (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physics & Mathematics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT96300127T 1995-01-09 1996-01-08 Radioaktives kupferkomplex von dithiosemicarbazonederivate oder diaminediolschiffbasederivate ATE210468T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP1750495		1995-01-09

Publications (1)

Publication Number	Publication Date
ATE210468T1 true ATE210468T1 (de)	2001-12-15

Family

ID=11945820

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96300127T ATE210468T1 (de)	1995-01-09	1996-01-08	Radioaktives kupferkomplex von dithiosemicarbazonederivate oder diaminediolschiffbasederivate

Country Status (9)

Country	Link
US (1)	US5843400A (de)
EP (1)	EP0726077B1 (de)
KR (1)	KR100419760B1 (de)
AT (1)	ATE210468T1 (de)
AU (1)	AU702169B2 (de)
CA (1)	CA2166676C (de)
DE (1)	DE69617763T2 (de)
DK (1)	DK0726077T3 (de)
ES (1)	ES2169207T3 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9705521D0 (en)	1997-03-18	1997-05-07	Univ Sheffield	The use of mononuclear phagocytes in the vivo imaging of hypoxic/ischaemic tissue
TWI252847B (en) *	2001-07-10	2006-04-11	Synta Pharmaceuticals Corp	Synthesis of taxol enhancers
MX2007012688A (es) *	2005-04-15	2008-03-14	Synta Pharmaceuticals Corp	Terapia de combinacion para el cancer con compuestos de bis(tiohidrazida) amida.
GB0513812D0 (en)	2005-07-05	2005-08-10	Isis Innovation	Compounds for imaging and therapy
RU2475478C2 (ru)	2006-08-21	2013-02-20	Синта Фармасьютиклз Корп.	Соединения для лечения пролиферативных расстройств
JP2010502616A (ja) *	2006-08-31	2010-01-28	シンタファーマシューティカルズコーポレーション	癌を治療するためのビス（チオヒドラジドアミド）の組み合わせ
JP6017766B2 (ja)	2011-07-26	2016-11-02	株式会社Ihi	新規な金属サレン錯体化合物の抗がん剤
JP6046338B2 (ja)	2011-10-27	2016-12-14	株式会社Ihi	ラジカル抑制剤
KR20150050524A (ko) *	2012-04-17	2015-05-08	메리맥 파마슈티컬즈, 인크.	비침습적 이미징을 위한 조성물 및 방법
CA3074258A1 (en)	2017-09-01	2019-03-07	Oregon State University	Therapeutic metal complexes and ligands and methods of making and using same
CN109694391B (zh) *	2018-12-20	2021-03-23	广西师范大学	一种以2-氨基-5-氯二苯甲酮缩氨基硫脲为配体的铂配合物及其合成方法和应用
CN113735781B (zh) *	2021-08-18	2023-05-09	广西师范大学	一种铜配合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4795626A (en) *	1985-05-10	1989-01-03	University Of Cincinnati	99m Tc.sup.(III) myocardial imaging agents which are non-reducable in vivo
EP0322876A3 (de) *	1987-12-29	1990-09-05	Nihon Medi-Physics Co., Ltd.	Chelierende Verbindungen und deren Verwendung
JPH01186899A (ja) *	1988-01-18	1989-07-26	Nippon Mejifuijitsukusu Kk	膜透過性を有するＴｃ−９９ｍ単核錯体
US4917879A (en) *	1989-05-19	1990-04-17	University Of Cincinnati	99MTC(III) myocardial imaging agents that are effective in humans
US5079346A (en) *	1990-05-01	1992-01-07	Trustees Of The University Of Pennsylvania	Gallium-labelled imaging agents

1996
- 1996-01-05 CA CA002166676A patent/CA2166676C/en not_active Expired - Fee Related
- 1996-01-08 ES ES96300127T patent/ES2169207T3/es not_active Expired - Lifetime
- 1996-01-08 AT AT96300127T patent/ATE210468T1/de not_active IP Right Cessation
- 1996-01-08 DK DK96300127T patent/DK0726077T3/da active
- 1996-01-08 KR KR1019960000212A patent/KR100419760B1/ko not_active Expired - Fee Related
- 1996-01-08 AU AU40856/96A patent/AU702169B2/en not_active Ceased
- 1996-01-08 DE DE69617763T patent/DE69617763T2/de not_active Expired - Fee Related
- 1996-01-08 EP EP96300127A patent/EP0726077B1/de not_active Expired - Lifetime
- 1996-01-11 US US08/584,300 patent/US5843400A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US5843400A (en)	1998-12-01
DE69617763T2 (de)	2002-08-14
AU702169B2 (en)	1999-02-18
EP0726077B1 (de)	2001-12-12
DE69617763D1 (de)	2002-01-24
ES2169207T3 (es)	2002-07-01
EP0726077A3 (de)	1997-06-11
DK0726077T3 (da)	2002-03-04
KR960029339A (ko)	1996-08-17
CA2166676A1 (en)	1996-07-10
EP0726077A2 (de)	1996-08-14
AU4085696A (en)	1996-07-18
CA2166676C (en)	2007-05-01
KR100419760B1 (ko)	2004-07-05

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Legal Events

Date	Code	Title	Description
2002-03-15	UEP	Publication of translation of european patent specification
2008-10-15	REN	Ceased due to non-payment of the annual fee