|
US5948793A
(en)
*
|
1992-10-09 |
1999-09-07 |
Abbott Laboratories |
3-pyridyloxymethyl heterocyclic ether compounds useful in controlling neurotransmitter release
|
|
US5852041A
(en)
*
|
1993-04-07 |
1998-12-22 |
Sibia Neurosciences, Inc. |
Substituted pyridines useful as modulators of acethylcholine receptors
|
|
US5605908A
(en)
*
|
1994-10-24 |
1997-02-25 |
Eli Lilly And Company |
Heterocyclic compounds and their use
|
|
US5998404A
(en)
*
|
1994-10-24 |
1999-12-07 |
Eli Lilly And Company |
Heterocyclic compounds and their use
|
|
US5585388A
(en)
*
|
1995-04-07 |
1996-12-17 |
Sibia Neurosciences, Inc. |
Substituted pyridines useful as modulators of acetylcholine receptors
|
|
IL118279A
(en)
*
|
1995-06-07 |
2006-10-05 |
Abbott Lab |
Compounds 3 - Pyridyloxy (or Thio) Alkyl Heterocyclic Pharmaceutical Compositions Containing Them and Their Uses for Preparing Drugs to Control Synaptic Chemical Transmission
|
|
CA2237311A1
(en)
*
|
1995-11-13 |
1997-05-22 |
Walter William Offen |
Method for treating anxiety
|
|
US5794887A
(en)
|
1995-11-17 |
1998-08-18 |
Komerath; Narayanan M. |
Stagnation point vortex controller
|
|
US6979695B2
(en)
|
1996-04-23 |
2005-12-27 |
Targacept, Inc. |
Compounds capable of activating cholinergic receptors
|
|
US5629325A
(en)
*
|
1996-06-06 |
1997-05-13 |
Abbott Laboratories |
3-pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission
|
|
US6437138B1
(en)
|
1996-06-06 |
2002-08-20 |
Abbott Laboratories |
3-pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission
|
|
DE69717148T2
(de)
*
|
1996-12-10 |
2003-10-02 |
Abbott Laboratories, Abbott Park |
3-pyridylenantiomere und ihre verwendung als analgetika
|
|
US6133253A
(en)
*
|
1996-12-10 |
2000-10-17 |
Abbott Laboratories |
3-Pyridyl enantiomers and their use as analgesics
|
|
EP0978280A1
(de)
*
|
1997-04-26 |
2000-02-09 |
Sumitomo Pharmaceuticals Company, Limited |
2-azabicyclo verbindungen
|
|
US6525065B1
(en)
|
1997-06-30 |
2003-02-25 |
Targacept, Inc. |
Pharmaceutical compositions and methods for effecting dopamine release
|
|
US6624173B1
(en)
|
1997-06-30 |
2003-09-23 |
Targacept, Inc. |
Pharmaceutical compositions for treating and/or preventing CNS disorders
|
|
US7214686B2
(en)
|
1997-06-30 |
2007-05-08 |
Targacept, Inc. |
Pharmaceutical compositions and methods for effecting dopamine release
|
|
WO1999024422A1
(en)
*
|
1997-11-05 |
1999-05-20 |
Neurosearch A/S |
Azaring-ether derivatives and their use as nicotinic ach receptor modulators
|
|
PT1047690E
(pt)
*
|
1997-12-19 |
2004-07-30 |
Abbott Lab |
Compostos eter e tioeter heterociclicos uteis no controlo da transmissao quimica sinaptica
|
|
MXPA00009619A
(es)
|
1998-04-02 |
2006-03-09 |
Targacept Inc |
Composiciones farmaceuticas y metodos de uso.
|
|
WO1999051602A1
(en)
*
|
1998-04-02 |
1999-10-14 |
R.J. Reynolds Tobacco Company |
Azatricyclo[3.3.1.1] decane derivatives and pharmaceutical compositions containing them
|
|
US6218383B1
(en)
|
1998-08-07 |
2001-04-17 |
Targacept, Inc. |
Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
|
|
US6953855B2
(en)
|
1998-12-11 |
2005-10-11 |
Targacept, Inc. |
3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof
|
|
US6432975B1
(en)
*
|
1998-12-11 |
2002-08-13 |
Targacept, Inc. |
Pharmaceutical compositions and methods for use
|
|
US20010031771A1
(en)
|
1999-05-24 |
2001-10-18 |
Gary Maurice Dull |
Pharmaceutical compositions and methods for use
|
|
US6544976B1
(en)
|
1999-07-09 |
2003-04-08 |
Ortho-Mcneil Pharmaceutical, Inc. |
Neurotrophic 2-azetidinecarboxylic acid derivatives, and related compositions and methods
|
|
MXPA02002115A
(es)
*
|
1999-09-14 |
2002-10-31 |
Abbott Lab |
Compuestos de eter 3-pirrolidiniloxi-3'-piridilico, utiles para controlar la transmision sinaptica quimica. .
|
|
US6890935B2
(en)
|
1999-11-01 |
2005-05-10 |
Targacept, Inc. |
Pharmaceutical compositions and methods for use
|
|
US6812314B2
(en)
|
2001-10-17 |
2004-11-02 |
University Of Florida |
Thermally responsive polymer materials and uses thereof
|
|
HUP0501017A3
(en)
|
2001-12-14 |
2010-06-28 |
Targacept |
Methods and compositions for treatment of central nervous system disorders
|
|
DK1519939T5
(da)
|
2002-07-05 |
2011-01-24 |
Targacept Inc |
N-Aryl-diazaspirocykliske forbindelser og fremgangsmåder til fremstilling og anvendelse deraf
|
|
WO2004009775A2
(en)
|
2002-07-19 |
2004-01-29 |
Targacept, Inc. |
Methods and compositions relating to chimeric nicotinic receptor subunits
|
|
GB0220581D0
(en)
|
2002-09-04 |
2002-10-09 |
Novartis Ag |
Organic Compound
|
|
US7098331B2
(en)
|
2003-03-05 |
2006-08-29 |
Targacept, Inc. |
Arylvinylazacycloalkane compounds and methods of preparation and use thereof
|
|
WO2005037832A2
(en)
|
2003-10-15 |
2005-04-28 |
Targacept, Inc. |
Azabicycyclic compounds for relieving pain and treating central nervous system disorders
|
|
AR049401A1
(es)
|
2004-06-18 |
2006-07-26 |
Novartis Ag |
Aza-biciclononanos
|
|
GB0415746D0
(en)
|
2004-07-14 |
2004-08-18 |
Novartis Ag |
Organic compounds
|
|
AU2005284908B2
(en)
|
2004-09-13 |
2011-12-08 |
Morningside Venture Investments Limited |
Biosynchronous transdermal drug delivery
|
|
CN101044134A
(zh)
|
2004-09-20 |
2007-09-26 |
塔加西普特公司 |
具有烟碱性胆碱能受体活性的氮杂螺烯和氮杂螺烷化合物
|
|
US7459469B2
(en)
|
2004-11-10 |
2008-12-02 |
Targacept, Inc. |
Hydroxybenzoate salts of metanicotine compounds
|
|
UA88792C2
(ru)
|
2004-11-10 |
2009-11-25 |
Таргасепт, Інк. |
Гидроксибензоатные соли метаникотиновых соединений
|
|
US7732607B2
(en)
|
2005-08-22 |
2010-06-08 |
Anatoly Mazurov |
Heteroaryl-substituted diazatricycloalkanes and methods of use thereof
|
|
GB0521508D0
(en)
|
2005-10-21 |
2005-11-30 |
Novartis Ag |
Organic compounds
|
|
GB0525672D0
(en)
|
2005-12-16 |
2006-01-25 |
Novartis Ag |
Organic compounds
|
|
GB0525673D0
(en)
|
2005-12-16 |
2006-01-25 |
Novartis Ag |
Organic compounds
|
|
TWI389889B
(zh)
|
2006-05-09 |
2013-03-21 |
Targacept Inc |
(2s)-(4e)-n-甲基-5-〔3-(5-異丙氧基吡啶)基〕-4-戊烯-2-胺之新穎多晶型
|
|
US8017785B2
(en)
|
2006-05-09 |
2011-09-13 |
Astrazeneca Ab |
Salt forms of (2S)-(4E)-N-methyl-5-[3-(5-isopropoxypyridin)y1]-4-penten 2-amine
|
|
TWI454262B
(zh)
|
2006-11-02 |
2014-10-01 |
Targacept Inc |
菸鹼乙醯膽鹼受體亞型選擇性之二氮雜雙環烷類醯胺
|
|
US20100069244A1
(en)
*
|
2006-11-29 |
2010-03-18 |
Basf Se |
Pyridine Compounds for Combating Pests
|
|
WO2008091588A1
(en)
|
2007-01-22 |
2008-07-31 |
Targacept, Inc. |
Intranasal, buccal, and sublingual administration of metanicotine analogs
|
|
TW200845977A
(en)
|
2007-03-30 |
2008-12-01 |
Targacept Inc |
Sub-type selective azabicycloalkane derivatives
|
|
CN103977003A
(zh)
|
2007-04-02 |
2014-08-13 |
帕金森氏病研究院 |
用于降低治疗的副作用的方法和组合物
|
|
SA08290475B1
(ar)
|
2007-08-02 |
2013-06-22 |
Targacept Inc |
(2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه
|
|
WO2009046025A1
(en)
|
2007-10-01 |
2009-04-09 |
Comentis, Inc. |
Quinuclidin-4-ylmethyl 1h-indole-3-carboxylate derivatives as alpha 7 nicotinic acetylcholine receptor ligands for the treatment of alzheimer's disease
|
|
EP2342192A4
(de)
*
|
2008-10-14 |
2012-05-09 |
Psychogenics Inc |
Nikotinacetylcholin-rezeptorliganden und ihre verwendungen
|
|
WO2010065443A1
(en)
|
2008-12-01 |
2010-06-10 |
Targacept, Inc. |
Synthesis and novel salt forms of (r)-5-((e)-2-(pyrrolidin-3-ylvinyl)pyrimidine
|
|
US9145396B2
(en)
|
2008-12-01 |
2015-09-29 |
Targacept, Inc. |
Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
|
|
TW201024283A
(en)
|
2008-12-01 |
2010-07-01 |
Targacept Inc |
Synthesis and novel salt forms of (R)-3-((E)-2-(pyrrolidin-3-yl)vinyl)-5-(tetrahydropyran-4-yloxy)pyridine
|
|
WO2010080757A2
(en)
|
2009-01-07 |
2010-07-15 |
Astrazeneca Ab |
Combinations with an alpha-4beta-2 nicotinic agonist
|
|
TW201031664A
(en)
|
2009-01-26 |
2010-09-01 |
Targacept Inc |
Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
|
|
US8802694B2
(en)
|
2009-12-07 |
2014-08-12 |
Targacept, Inc. |
3,6-diazabicyclo[3.1.1]heptanes as neuronal nicotinic acetycholine receptor ligands
|
|
CN103180277A
(zh)
|
2010-05-20 |
2013-06-26 |
塔格塞普特股份有限公司 |
制备芳基取代的烯属胺的新方法
|
|
MX337106B
(es)
|
2010-05-27 |
2016-02-12 |
Targacept Inc |
Antagonistas no competitivos de receptores nicotinicos.
|
|
WO2012125518A1
(en)
|
2011-03-14 |
2012-09-20 |
Targacept, Inc. |
Salt forms of 3 - cyclopropylcarbonyl - 3, 6 - diazabicyclo [3.1.1] heptane
|
|
WO2012129262A1
(en)
|
2011-03-23 |
2012-09-27 |
Targacept, Inc. |
Treatment of attention deficit/hyperactivity disease
|
|
TW201311698A
(zh)
|
2011-08-22 |
2013-03-16 |
Targacept Inc |
作為神經元菸鹼乙醯膽鹼受體配位體之1,4-二氮雜雙環[3.2.2]壬烷
|
|
WO2013071097A1
(en)
|
2011-11-11 |
2013-05-16 |
Georgetown University |
2,5-disubstituted-pyridyl nicotinic ligands, and methods of use thereof
|
|
JP2017524736A
(ja)
|
2014-07-11 |
2017-08-31 |
アルファーマゲン,エルエルシー |
アルファ7−ニコチン性アセチルコリン受容体活性を調節するためのキヌクリジン化合物
|
|
AU2016211330A1
(en)
|
2015-01-28 |
2017-08-03 |
Chrono Therapeutics Inc. |
Drug delivery methods and systems
|
|
US9724340B2
(en)
|
2015-07-31 |
2017-08-08 |
Attenua, Inc. |
Antitussive compositions and methods
|
|
CN105418477B
(zh)
*
|
2015-12-22 |
2018-12-21 |
爱斯特(成都)生物制药股份有限公司 |
降低雷迪帕韦中间体中非对映异构体杂质含量的方法
|
|
CA3049529A1
(en)
|
2017-01-06 |
2018-07-12 |
Chrono Therapeutics Inc. |
Transdermal drug delivery devices and methods
|
|
US11596779B2
(en)
|
2018-05-29 |
2023-03-07 |
Morningside Venture Investments Limited |
Drug delivery methods and systems
|
|
US12397141B2
(en)
|
2018-11-16 |
2025-08-26 |
Morningside Venture Investments Limited |
Thermally regulated transdermal drug delivery system
|
|
EP4172156A1
(de)
*
|
2020-06-24 |
2023-05-03 |
Philip Morris Products S.A. |
Zusammensetzungen und verfahren zur bekämpfung von parasiten
|