ATE21105T1 - 7-oxo-4-thia-1-aza(3.2.0)heptan- und 7-oxo-4-thia-1-aza-(3.2.0)hept-2-en-derivate. - Google Patents

7-oxo-4-thia-1-aza(3.2.0)heptan- und 7-oxo-4-thia-1-aza-(3.2.0)hept-2-en-derivate.

Info

Publication number: ATE21105T1
Authority: AT; Austria
Prior art keywords: thia; oxo; aza; hept; derivatives
Prior art date: 1980-11-06

Application number

AT81109176T

Other languages

English (en)

Inventor

Barry Clive Dr Ross

Graham Dr Johnson

Michael Alan Dr Yeomans

Original Assignee

Hoechst Uk Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-11-06

Filing date

1981-10-29

Publication date

1986-08-15

1981-10-29 Application filed by Hoechst Uk Ltd filed Critical Hoechst Uk Ltd

1986-08-15 Application granted granted Critical

1986-08-15 Publication of ATE21105T1 publication Critical patent/ATE21105T1/de

Links

IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 title 2
OTTZHAVKAVGASB-UHFFFAOYSA-N 2-heptene Natural products CCCCC=CC OTTZHAVKAVGASB-UHFFFAOYSA-N 0.000 title 1
HHXMXAQDOUCLDN-UHFFFAOYSA-N 4-thia-1-azabicyclo[3.2.0]hept-2-en-7-one Chemical class S1C=CN2C(=O)CC21 HHXMXAQDOUCLDN-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

AT81109176T 1980-11-06 1981-10-29 7-oxo-4-thia-1-aza(3.2.0)heptan- und 7-oxo-4-thia-1-aza-(3.2.0)hept-2-en-derivate. ATE21105T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8035657		1980-11-06
EP81109176A EP0051813B1 (de)	1980-11-06	1981-10-29	7-Oxo-4-thia-1-aza(3.2.0)heptan- und 7-Oxo-4-thia-1-aza-(3.2.0)hept-2-en-Derivate

Publications (1)

Publication Number	Publication Date
ATE21105T1 true ATE21105T1 (de)	1986-08-15

Family

ID=10517119

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT81109176T ATE21105T1 (de)	1980-11-06	1981-10-29	7-oxo-4-thia-1-aza(3.2.0)heptan- und 7-oxo-4-thia-1-aza-(3.2.0)hept-2-en-derivate.

Country Status (7)

Country	Link
US (3)	US4474793A (de)
EP (2)	EP0176064A1 (de)
JP (1)	JPS57108092A (de)
AT (1)	ATE21105T1 (de)
CA (1)	CA1197839A (de)
DE (1)	DE3175042D1 (de)
GB (1)	GB2087880B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE8101464L (sv) *	1980-03-10	1981-09-11	Sankyo Co	2-penem-3-karboxylsyraderivat, deras framstellning och anvendning
GB2083462B (en) *	1980-08-16	1984-05-02	Beecham Group Ltd	2-thiopenem derivatives
ES8305366A1 (es) *	1981-07-08	1983-04-01	Hoechst Uk Ltd	"procedimiento para la preparacion de derivados de penem".
EP0185651A1 (de) *	1981-07-08	1986-06-25	Hoechst Uk Limited	Zwischenprodukte zur Herstellung von antibakteriellen Penemderivaten
EP0091576B1 (de) *	1982-03-26	1987-07-29	Hoechst Uk Limited	7-Oxo-4-thia-1-azabicyclo(3,2,0)Heptan-Derivate
GB2159519B (en) *	1982-03-26	1986-08-20	Hoechst Uk Ltd	7-oxo-4-thia-1-azabicyclo3,2,0heptane derivatives; azetidinones
CA1221358A (en) *	1982-12-08	1987-05-05	Erba Farmitalia	2-thiacephems and (5r) penems derivatives
EP0320497A1 (de) *	1983-01-25	1989-06-14	Merck & Co. Inc.	Substituierte 2-Thioxopename, deren Zwischenprodukte und Verfahren zur Herstellung von substituierten 2-Thioxopenamen und 2-substituierten Thiopenemen
US4610823A (en) *	1983-01-25	1986-09-09	Merck & Co., Inc.	Process for preparing substituted 2-thioxopenams and 2-substituted thiopenems
EP0115308A3 (de) *	1983-01-25	1984-10-10	Merck & Co. Inc.	2-Ungesättigte Alkylthio-Pen-2-em-3-Carbonsäuren und Verfahren zur Herstellung von substituierten 2-Thioxopenamen und 2-substituierten Thiopenemen
US4725678A (en) *	1983-06-10	1988-02-16	Pfizer Inc.	Azetidinone intermediates for the preparation of penem derivatives
US4595539A (en) *	1983-06-10	1986-06-17	Pfizer Inc.	Preparation of penem derivatives and azetidinone intermediates
US4619783A (en) *	1983-06-10	1986-10-28	Pfizer Inc.	Process and intermediates for the preparation of penem derivatives
US5229381A (en) *	1983-12-01	1993-07-20	Merck & Co., Inc.	Substituted azetidinones as anti-inflammatory and antidegenerative agents
US4680391A (en) *	1983-12-01	1987-07-14	Merck & Co., Inc.	Substituted azetidinones as anti-inflammatory and antidegenerative agents
US5229510A (en) *	1983-12-01	1993-07-20	Merck & Co., Inc.	β-lactams useful in determining the amount of elastase in a clinical sample
US4791198A (en) *	1984-07-05	1988-12-13	Kanegafuchi Kagaku Kogyo Kabushiki Kaisha	Beta-lactam compound and preparation thereof
US4861877A (en) *	1984-07-05	1989-08-29	Kanegafuchi Kagaku Kogyo Kabushiki Kaisha	Process for preparing 4-acetoxy-3-hydroxyethylazetidin-2-one derivatives
US4782145A (en) *	1986-06-02	1988-11-01	Pfizer Inc.	Process for penem derivatives
US4695626A (en) *	1986-07-29	1987-09-22	Pfizer Inc.	1-aza-4,5-dithiabicyclo [4.2.0] oct-2-en-8-one-2 carboxylate esters
US5100880A (en) *	1991-03-20	1992-03-31	Merck & Co., Inc.	Novel betalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
US5104862A (en) *	1991-03-20	1992-04-14	Merck & Co., Inc.	Bethalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
US5348953A (en) *	1991-06-25	1994-09-20	Merck & Co., Inc.	Substituted azetidinones as anti-inflammatory and antidegenerative agents
CA2147129A1 (en) *	1992-10-27	1994-05-11	James B. Doherty	New substituted azetidinones as anti-inflammatory and antidegenerative agents
US5591737A (en) *	1992-12-17	1997-01-07	Merck & Co., Inc.	Substituted azetidinones as anti-inflammatory and antidegenerative agents
TW467896B (en)	1993-03-19	2001-12-11	Bristol Myers Squibb Co	Novel β-lactams, methods for the preparation of taxanes and sidechain-bearing taxanes
US5747485A (en) *	1995-04-13	1998-05-05	Merck & Co., Inc.	Substituted azetidiones as anti-inflammatory and antidegenerative agents
PL368945A1 (en) *	2001-11-30	2005-04-04	Bristol-Myers Squibb Company	Paclitaxel solvates
US7482366B2 (en)	2001-12-21	2009-01-27	X-Ceptor Therapeutics, Inc.	Modulators of LXR
US7998986B2 (en)	2001-12-21	2011-08-16	Exelixis Patent Company Llc	Modulators of LXR
KR101122603B1 (ko) *	2008-10-02	2012-03-15	유형근	사운드 송출 기능을 갖는 알에프 전자카드

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH541576A (de) *	1970-11-03	1973-09-15	Ciba Geigy Ag	Verfahren zur Herstellung thiaheterocyclischer Verbindungen
LU77306A1 (de) *	1977-05-09	1979-01-18
JPS5466695A (en) *	1977-11-08	1979-05-29	Sankyo Co Ltd	Azetidinone derivative and its preparation
EP0042026B1 (de) *	1978-02-02	1986-01-08	Ciba-Geigy Ag	3,4-Disubstituierte Azetidin-2-onverbindungen und Verfahren zu ihrer Herstellung
US4290948A (en) *	1978-11-22	1981-09-22	Beecham Group Limited	Process for their preparation of β-lactam antibacterial agents
SE8101464L (sv) *	1980-03-10	1981-09-11	Sankyo Co	2-penem-3-karboxylsyraderivat, deras framstellning och anvendning
JPS572290A (en) *	1980-06-03	1982-01-07	Sankyo Co Ltd	Production of penem-3-carboxylic derivative

1981
- 1981-10-29 EP EP85111993A patent/EP0176064A1/de not_active Withdrawn
- 1981-10-29 DE DE8181109176T patent/DE3175042D1/de not_active Expired
- 1981-10-29 AT AT81109176T patent/ATE21105T1/de not_active IP Right Cessation
- 1981-10-29 EP EP81109176A patent/EP0051813B1/de not_active Expired
- 1981-11-04 US US06/318,113 patent/US4474793A/en not_active Expired - Fee Related
- 1981-11-05 CA CA000389542A patent/CA1197839A/en not_active Expired
- 1981-11-05 JP JP56176568A patent/JPS57108092A/ja active Pending
- 1981-11-06 GB GB8133564A patent/GB2087880B/en not_active Expired
1983
- 1983-08-22 US US06/524,973 patent/US4510086A/en not_active Expired - Fee Related
- 1983-08-22 US US06/524,977 patent/US4526718A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0176064A1 (de)	1986-04-02
US4474793A (en)	1984-10-02
GB2087880A (en)	1982-06-03
EP0051813A2 (de)	1982-05-19
CA1197839A (en)	1985-12-10
DE3175042D1 (en)	1986-09-04
EP0051813A3 (en)	1982-08-18
EP0051813B1 (de)	1986-07-30
JPS57108092A (en)	1982-07-05
US4526718A (en)	1985-07-02
GB2087880B (en)	1985-05-01
US4510086A (en)	1985-04-09

Legal Events

Date	Code	Title	Description
1986-11-15	UEP	Publication of translation of european patent specification
1990-07-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE21105T1 (de)	1986-08-15	7-oxo-4-thia-1-aza(3.2.0)heptan- und 7-oxo-4-thia-1-aza-(3.2.0)hept-2-en-derivate.
FI852974L (fi)	1986-02-04	Nya n-hydroxylgruppen skyddande grupper och framstaellningsfoerfarande foer 3-acylamino-1-hydroxi-2-azetidinoner.
NO902394L (no)	1990-12-03	Fremgangsmaate for fremstilling av pyranyl-cyanoguanidin-derivater.
ES543153A0 (es)	1987-02-16	Metodo de preparar derivados de b-carbolin-3-oxadiazolilo
NO894349L (no)	1990-05-03	Tienopyridin-type mevalonolaktoner.
PL268034A1 (en)	1988-09-01	The method of manufacture of new 7-phenylglycil-1-carbo-destiacephalosphorines
ES2053809T3 (es)	1994-08-01	Derivados de ciclopropano.
ATE40369T1 (de)	1989-02-15	Purinderivate.
FI862336A0 (fi)	1986-06-02	Nytt foerfarande foer framstaellning av 7-aca-derivat.
FI901277A0 (fi)	1990-03-14	2,5,6,7-tetranor-4,8-inter-m-fenylen pg1z-derivativ.
GR79558B (de)	1984-10-30
SE8504409D0 (sv)	1985-09-24	Novel chemical intermediates
IE812607L (en)	1982-05-10	Heterobicyclic compounds
DE3461189D1 (en)	1986-12-11	New 3-alkylthio-2-o-carbamoyl-propane-1.2-diol-1-o-phosphocholines, and processes for their preparation
DE3464915D1 (en)	1987-08-27	(5-(2-aminomethyl-imidazol-1-yl)-1,3-dialkyl-1h-pyrazol-4-yl)(aryl)methanones and processes for their production
JPS57158754A (en)	1982-09-30	Improvement on organic compounds
ATE66459T1 (de)	1991-09-15	Herstellungsverfahren von trifluormethylverbindungen.
AR241135A2 (es)	1991-11-29	"derivados de n-triazinil-n-sulfamoilurea herbicidamente activos y formulacion herbicida que los contiene".
FR2367746A2 (fr)	1978-05-12	Derives de (1-(o,o,
ES2039270T3 (es)	1993-09-16	Derivados de gamma-l-glutamil-4-nitroanilida y procedimiento para determinar actividad de gamma-gtp utilizandolos.