ATE210966T1 - Reduzierung von durch liposome induzierte physiologischen gegenreaktionen - Google Patents

Reduzierung von durch liposome induzierte physiologischen gegenreaktionen

Info

Publication number
ATE210966T1
ATE210966T1 AT94918106T AT94918106T ATE210966T1 AT E210966 T1 ATE210966 T1 AT E210966T1 AT 94918106 T AT94918106 T AT 94918106T AT 94918106 T AT94918106 T AT 94918106T AT E210966 T1 ATE210966 T1 AT E210966T1
Authority
AT
Austria
Prior art keywords
counterreactions
liposomes
induced
liposome
animal
Prior art date
Application number
AT94918106T
Other languages
English (en)
Inventor
Patrick L Ahl
Suresh K Bhatia
Sharma R Minchey
Andrew S Janoff
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Application granted granted Critical
Publication of ATE210966T1 publication Critical patent/ATE210966T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT94918106T 1993-05-21 1994-05-20 Reduzierung von durch liposome induzierte physiologischen gegenreaktionen ATE210966T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6592893A 1993-05-21 1993-05-21
US20765194A 1994-03-07 1994-03-07
PCT/US1994/005824 WO1994027580A1 (en) 1993-05-21 1994-05-20 Reduction of liposome-induced adverse physiological reactions

Publications (1)

Publication Number Publication Date
ATE210966T1 true ATE210966T1 (de) 2002-01-15

Family

ID=26746185

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94918106T ATE210966T1 (de) 1993-05-21 1994-05-20 Reduzierung von durch liposome induzierte physiologischen gegenreaktionen

Country Status (15)

Country Link
US (2) US5614214A (de)
EP (2) EP0699068B1 (de)
JP (1) JPH08510748A (de)
KR (1) KR960702297A (de)
AT (1) ATE210966T1 (de)
AU (1) AU680513B2 (de)
CA (1) CA2160118A1 (de)
DE (2) DE69429511T2 (de)
DK (1) DK0699068T3 (de)
ES (2) ES2165875T3 (de)
GR (1) GR20010300075T1 (de)
NO (1) NO954691L (de)
NZ (1) NZ267310A (de)
PT (1) PT699068E (de)
WO (1) WO1994027580A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL314132A1 (en) * 1993-11-04 1996-08-19 Schering Ag Method of obtained electrically charged liposomes
US5885613A (en) * 1994-09-30 1999-03-23 The University Of British Columbia Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
US5820873A (en) * 1994-09-30 1998-10-13 The University Of British Columbia Polyethylene glycol modified ceramide lipids and liposome uses thereof
ATE198419T1 (de) * 1994-10-14 2001-01-15 Liposome Co Inc Etherlipid-liposomen und deren therapeutische verwendung
US6673364B1 (en) 1995-06-07 2004-01-06 The University Of British Columbia Liposome having an exchangeable component
US6667053B1 (en) 1996-02-16 2003-12-23 Elan Pharmaceuticals, Inc. D and L etherlipid stereoisomers and liposomes
US5965159A (en) * 1996-02-16 1999-10-12 The Liposome Company, Inc. Etherlipid-containing multiple lipid liposomes
US6007839A (en) * 1996-02-16 1999-12-28 The Liposome Company, Inc. Preparation of pharmaceutical compositions containing etherlipid-containing multiple lipid liposomes
USRE39042E1 (en) * 1996-02-16 2006-03-28 The Liposome Company, Inc. Etherlipid-containing multiple lipid liposomes
US5942246A (en) * 1996-02-16 1999-08-24 The Liposome Company, Inc. Etherlipid containing multiple lipid liposomes
US20030199425A1 (en) * 1997-06-27 2003-10-23 Desai Neil P. Compositions and methods for treatment of hyperplasia
US6734171B1 (en) 1997-10-10 2004-05-11 Inex Pharmaceuticals Corp. Methods for encapsulating nucleic acids in lipid bilayers
EP0976394A1 (de) * 1998-07-30 2000-02-02 Biosearch Italia S.p.A. Neue injizierbare Formulierungen
US6593308B2 (en) * 1999-12-03 2003-07-15 The Regents Of The University Of California Targeted drug delivery with a hyaluronan ligand
ES2332584T3 (es) * 2001-03-27 2010-02-09 Phares Pharmaceutical Research N.V. Metodo y composicion para solubilizar un compuesto biologicamente activo con baja solubilidad en agua.
JP2005525992A (ja) * 2001-06-25 2005-09-02 イサム・リサーチ・デベロツプメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシテイ・オブ・エルサレム 生物学的物質を充填した小胞の調製法およびそれらの様々な使用
US20030180348A1 (en) * 2002-03-22 2003-09-25 Levinson R. Saul Transcellular drug delivery system
US6811777B2 (en) 2002-04-13 2004-11-02 Allan Mishra Compositions and minimally invasive methods for treating incomplete connective tissue repair
US7462703B2 (en) * 2003-01-31 2008-12-09 Max-Delbruck-Centrum Fur Molekulare Medizin Agent for gene transfer
CN1319520C (zh) * 2005-02-03 2007-06-06 上海交通大学 核苷膦酸类化合物的脂质体和脂质复合物制剂
US8080262B2 (en) * 2006-10-24 2011-12-20 Northwestern University Encapsulated peptide amphiphile nanostructures
US20100112081A1 (en) 2008-10-07 2010-05-06 Bioparadox, Llc Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities
EP2486923B1 (de) * 2011-02-11 2015-09-09 Dr. Felix Jäger und Dr. Stefan Drinkuth Laborgemeinschaft OHG Histon-Deacetylase (HDAC) hemmende Verbindungen und Verfahren zu deren Herstellung
US20140356893A1 (en) 2013-06-04 2014-12-04 Allan Mishra Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation
US20210154307A1 (en) 2019-11-07 2021-05-27 Northeastern University Cationic nanostructures for intra-cartilage delivery of therapeutics and contrast agents

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3577446A (en) * 1968-09-09 1971-05-04 American Home Prod Phosphatidylalkanolamine derivatives
US3993754A (en) * 1974-10-09 1976-11-23 The United States Of America As Represented By The United States Energy Research And Development Administration Liposome-encapsulated actinomycin for cancer chemotherapy
US4086257A (en) * 1976-10-12 1978-04-25 Sears Barry D Phosphatidyl quaternary ammonium compounds
CH624011A5 (de) * 1977-08-05 1981-07-15 Battelle Memorial Institute
CH621479A5 (de) * 1977-08-05 1981-02-13 Battelle Memorial Institute
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4522803A (en) * 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
US5030453A (en) * 1983-03-24 1991-07-09 The Liposome Company, Inc. Stable plurilamellar vesicles
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
WO1985000968A1 (en) * 1983-09-06 1985-03-14 Health Research, Inc. Liposome delivery method for decreasing the toxicity of an antitumor drug
US4721612A (en) * 1984-04-12 1988-01-26 The Liposome Company, Inc. Steroidal liposomes
US5008050A (en) * 1984-06-20 1991-04-16 The Liposome Company, Inc. Extrusion technique for producing unilamellar vesicles
CA1264668C (en) * 1984-06-20 1990-01-23 EXTRUSION TECHNIQUES FOR THE PRODUCTION OF LIPOSOMES
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
CA1270198A (en) * 1984-08-08 1990-06-12 Marcel B. Bally Encapsulation of antineoplastic agents in liposomes
US5077056A (en) * 1984-08-08 1991-12-31 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
JPS6188887A (ja) * 1984-10-08 1986-05-07 Meito Sangyo Kk 酵素法１−ｏ−アルキル−２−アシルグリセロリン脂質誘導体の製法
US4975282A (en) * 1985-06-26 1990-12-04 The Liposome Company, Inc. Multilamellar liposomes having improved trapping efficiencies
DE3689769T2 (de) * 1985-07-05 1994-07-21 Liposome Co Inc Multilamellare liposome mit verbesserter einschliessungswirkung.
PH26160A (en) * 1985-08-19 1992-03-18 Univ Texas Pharmaceutical compositions consisting of acylated phospholipids
US5041278A (en) * 1985-10-15 1991-08-20 The Liposome Company, Inc. Alpha tocopherol-based vesicles
US4861580A (en) * 1985-10-15 1989-08-29 The Liposome Company, Inc. Composition using salt form of organic acid derivative of alpha-tocopheral
NZ223660A (en) * 1987-03-05 1990-11-27 Liposome Co Inc Low toxicity drug-lipid complexes; methods of making them; and method of determining their toxicity
CH672733A5 (de) * 1987-05-22 1989-12-29 Bracco Ind Chimica Spa
US5080833A (en) * 1987-09-21 1992-01-14 Kabushiki Kaisha Toshiba Immobilization of bioactive substance on lipid composition containing modified lipid compound
EP0472639A4 (en) * 1989-05-15 1992-07-01 The Liposome Company, Inc. Accumulation of drugs into liposomes by a proton gradient
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
CA2093665A1 (en) * 1990-10-09 1992-04-10 Sean M. Sullivan Phospholipid analogue vesicle
US5313804A (en) * 1993-04-23 1994-05-24 Maritime Geothermal Ltd. Direct expansion geothermal heat pump

Also Published As

Publication number Publication date
WO1994027580A1 (en) 1994-12-08
DK0699068T3 (da) 2002-03-11
GR20010300075T1 (en) 2001-12-31
US5614214A (en) 1997-03-25
US5662930A (en) 1997-09-02
ES2165875T3 (es) 2002-04-01
CA2160118A1 (en) 1994-12-08
DE69429511D1 (de) 2002-01-31
EP1118326A2 (de) 2001-07-25
DE69429511T2 (de) 2002-05-16
AU680513B2 (en) 1997-07-31
KR960702297A (ko) 1996-04-27
DE1118326T1 (de) 2002-04-18
EP0699068A1 (de) 1996-03-06
PT699068E (pt) 2002-06-28
AU6956894A (en) 1994-12-20
EP1118326A3 (de) 2002-07-31
NZ267310A (en) 1996-09-25
NO954691D0 (no) 1995-11-20
NO954691L (no) 1995-11-20
JPH08510748A (ja) 1996-11-12
ES2193005T1 (es) 2003-11-01
EP0699068B1 (de) 2001-12-19

Similar Documents

Publication Publication Date Title
ATE210966T1 (de) Reduzierung von durch liposome induzierte physiologischen gegenreaktionen
HU9403823D0 (en) Moisturizing composition for the simultaneous treatment of the surface layers and deep layers of the skin, and use thereof
ZA892365B (en) Anesthetic/skin moisturizing composition and method of preparing same
EP0251717A3 (de) Chemisch modifiziertes, die Inselzellen aktivierendes Protein
EP0268220A3 (en) Penetration enhancers for transdermal delivery of systemic agents
EP0728476A4 (de) Liposomenzusammensetzung
SE8803713D0 (sv) Biologically active lipoprotein and its use
ATE183075T1 (de) Retinoid enthaltendes mittel
ATE225646T1 (de) Perkutan verabreichbare basiszusammensetzung und daraus hergestellte zusammensetzung
FR2623716B1 (fr) Composition a base de phases lamellaires lipidiques hydratees ou de liposomes contenant de la tyrosine ou un derive de tyrosine et composition cosmetique ou pharmaceutique, notamment dermatologique, a activite pigmentante, l'incorporant
AU629445B2 (en) Improvements in or relating to topical compositions containing 1 alpha 25-dihydroxycholecalciferol
NO930042L (no) Kosmetisk eller dermatologisk sammensetning inneholdende en dioleste
ES2084348T3 (es) N-((4,5-dihidroxi- y 4,5,8-trihidroxi-9,10-dihidro-9,10-dioxo-2-antracen-il)carbonil)aminoacidos utiles en la terapia de afecciones osteoarticulares.
EP0335446A3 (de) Mittel zur Behandlung von Neoplasmen
DE3771548D1 (de) Verwendung von carbonsaeure in fuer topische anwendung vorgesehenen pharmazeutischen zubereitungen.
IL78269A (en) Dermatological therapeutical compositions containing imidazolidinylurea derivative
CA2170289A1 (en) A method of treating liver disease and like indications with vasodilating agents
IT8648228A0 (it) Impiego di l-carnitina nel trattamento degli effetti tossici indotti dall'inalazione di alotano e di altri anestetici generali alogenati
IT8647570A0 (it) Composizione farmaceutica comprendente trometamina per il trattamento per via topica dell'acne giovanile
IT8633816V0 (it) Dispositivo di sicurezza per la guida di veicoli in genere in caso di visibilita' ridotta o nulla.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee