ATE210967T1 - Magnetisch reagierende zusammensetzung als träger für biologisch aktive substanzen und verfahren für ihre herstellung und verwendung - Google Patents

Magnetisch reagierende zusammensetzung als träger für biologisch aktive substanzen und verfahren für ihre herstellung und verwendung

Info

Publication number
ATE210967T1
ATE210967T1 AT94908636T AT94908636T ATE210967T1 AT E210967 T1 ATE210967 T1 AT E210967T1 AT 94908636 T AT94908636 T AT 94908636T AT 94908636 T AT94908636 T AT 94908636T AT E210967 T1 ATE210967 T1 AT E210967T1
Authority
AT
Austria
Prior art keywords
biologically active
particles
production
active substances
carrier
Prior art date
Application number
AT94908636T
Other languages
English (en)
Inventor
Viktor Alexeevich Volkonsky
Sergei V Chernyakov
Sergei D Dvuhsherstnov
Original Assignee
Ferx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferx Inc filed Critical Ferx Inc
Application granted granted Critical
Publication of ATE210967T1 publication Critical patent/ATE210967T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5094—Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT94908636T 1993-01-29 1994-01-26 Magnetisch reagierende zusammensetzung als träger für biologisch aktive substanzen und verfahren für ihre herstellung und verwendung ATE210967T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1136393A 1993-01-29 1993-01-29
PCT/US1994/000892 WO1994016683A1 (en) 1993-01-29 1994-01-26 Magnetically responsive composition for carrying biologically active substances and methods of production and use

Publications (1)

Publication Number Publication Date
ATE210967T1 true ATE210967T1 (de) 2002-01-15

Family

ID=21750068

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94908636T ATE210967T1 (de) 1993-01-29 1994-01-26 Magnetisch reagierende zusammensetzung als träger für biologisch aktive substanzen und verfahren für ihre herstellung und verwendung

Country Status (11)

Country Link
US (3) US5549915A (de)
EP (1) EP0683665B1 (de)
JP (2) JP3145120B2 (de)
AT (1) ATE210967T1 (de)
AU (1) AU6165394A (de)
CA (1) CA2154913C (de)
DE (1) DE69429507T2 (de)
DK (1) DK0683665T3 (de)
ES (1) ES2165385T3 (de)
PT (1) PT683665E (de)
WO (1) WO1994016683A1 (de)

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US6200547B1 (en) * 1994-01-26 2001-03-13 Ferx Incorporated Magnetically responsive compositions for carrying biologically active substances and methods of production and use
EP0683665B1 (de) * 1993-01-29 2001-12-19 Ferx Incorporated Magnetisch reagierende zusammensetzung als träger für biologisch aktive substanzen und verfahren für ihre herstellung und verwendung
US6482436B1 (en) 1993-01-29 2002-11-19 Ferx Incorporated Magnetically responsive composition
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
US5985312A (en) * 1996-01-26 1999-11-16 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers
US6368586B1 (en) 1996-01-26 2002-04-09 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers
US7090636B2 (en) * 2000-03-31 2006-08-15 Fe Rx Incorporated Permanent magnet keeper-shield assembly
US6488615B1 (en) 2000-03-31 2002-12-03 Ferx Incorporated Permanent magnet keeper-shield assembly
WO2002069351A1 (en) * 2001-02-26 2002-09-06 University Of Utah Research Foundation Magnetic activated carbon particles for adsorption of solutes from solution
US6921283B2 (en) * 2001-08-27 2005-07-26 Trompeter Electronics, Inc. BNC connector having visual indication
FR2832598B1 (fr) * 2001-11-26 2006-01-27 Oreal Article de conditionnement et/ou d'application d'un produit
AU2003214812A1 (en) * 2002-01-09 2003-07-30 Ferx Incorporated Magnetic delivery compositions
EP1482956A1 (de) * 2002-02-01 2004-12-08 Vanderbilt University Gezielte arzneimittelabgabeverfahren
US8097185B2 (en) * 2002-02-26 2012-01-17 University Of Utah Research Foundation Magnetic activated carbon particles for adsorption of solutes from solution
US20040133099A1 (en) * 2002-12-18 2004-07-08 Dyer R. Kent Otologic nanotechnology
US8651113B2 (en) * 2003-06-18 2014-02-18 Swr&D Inc. Magnetically responsive nanoparticle therapeutic constructs and methods of making and using
US7723311B2 (en) * 2003-06-18 2010-05-25 Nanobiomagnetics, Inc. Delivery of bioactive substances to target cells
US7344491B1 (en) 2003-11-26 2008-03-18 Nanobiomagnetics, Inc. Method and apparatus for improving hearing
ES2264839B1 (es) * 2003-11-24 2007-10-01 Universidad De Zaragoza (Inst Denanociencia De Ar Agom. Farmacoterapia parenteral focalizada mediante el implante de imanes permanentes en los organos diana.
DE10359252A1 (de) * 2003-12-17 2005-07-28 Siemens Ag Navigierte Wärmebehandlung von Tumoren mit enzymumhüllten Eisenpartikeln
US20070100457A1 (en) * 2004-03-04 2007-05-03 Hyde Edward R Jr Paramagnetic liquid interface
US20070274907A1 (en) * 2004-03-26 2007-11-29 Yuhua Li Magnetically Targetable Mitomycin C Compositions and Methods of Their Use
US20060024378A1 (en) * 2004-08-02 2006-02-02 Mehta Rakesh H Magnetically responsive carbon nano-structures for transporting biologically active substances, and methods relating thereto
US20070281007A1 (en) * 2004-08-27 2007-12-06 Jacob Jules S Mucoadhesive Oral Formulations of High Permeability, High Solubility Drugs
US8568286B2 (en) * 2006-06-14 2013-10-29 Cardiac Pacemakers, Inc. Methods to position therapeutic agents using a magnetic field
CN103705947A (zh) 2006-06-28 2014-04-09 株式会社Ihi 药物、药物引导装置、磁性检测装置和药物设计方法
US20080097606A1 (en) * 2006-10-19 2008-04-24 Cragg Andrew H Knee joint prosthesis and hyaluronate compositions for treatment of osteoarthritis
US20090169484A1 (en) 2007-12-28 2009-07-02 Ihi Corporation Iron-salen complex
JP5433155B2 (ja) * 2008-02-20 2014-03-05 株式会社Ｉｈｉ 磁性を有する薬剤、薬剤の誘導システム、並びに磁気検出装置
JP2009274962A (ja) * 2008-05-12 2009-11-26 Yoshihiro Ishikawa 鉄サレン錯体、磁性を有する薬剤、薬剤の誘導システム、並びに磁気検出装置
RU2495045C2 (ru) 2008-11-20 2013-10-10 АйЭйчАй КОРПОРЕЙШН Комплексное соединение самонамагничивающегося металла с саленом
RU2525509C2 (ru) 2009-12-25 2014-08-20 АйЭйчАй КОРПОРЕЙШН Магнитное тело и устройство управления доставкой лекарственного средства с использованием магнитного тела
WO2011151978A1 (ja) 2010-06-01 2011-12-08 株式会社Ihi 蛍光色素材料及びその使用方法
US9744235B2 (en) 2010-10-19 2017-08-29 The Board Of Regents Of The University Of Oklahoma Treatment of cardiovascular disorders with targeted nanoparticles
US8740872B2 (en) 2010-10-19 2014-06-03 The Board Of Regents Of The University Of Oklahoma Magnetically-targeted treatment for cardiac disorders
US10398668B2 (en) 2010-10-19 2019-09-03 The Board Of Regents Of The University Of Oklahoma Glutamate treatment of cardiovascular disorders
SG192062A1 (en) * 2010-12-21 2013-08-30 Ihi Corp Metal-salen complex compound and production method for same
JP2012176905A (ja) * 2011-02-25 2012-09-13 Ihi Corp 金属サレン錯体化合物
JP2012131737A (ja) * 2010-12-21 2012-07-12 Ihi Corp 金属サレン錯体化合物及びその製造方法
JP2012167067A (ja) 2011-02-15 2012-09-06 Ihi Corp 自己磁性金属サレン錯体化合物
JP5873656B2 (ja) 2011-06-13 2016-03-01 株式会社Ihi 金属サレン錯体化合物、局所麻酔薬剤及び抗悪性腫瘍薬剤
JP6017766B2 (ja) 2011-07-26 2016-11-02 株式会社Ihi 新規な金属サレン錯体化合物の抗がん剤
RU2595840C2 (ru) 2011-10-04 2016-08-27 АйЭйчАй КОРПОРЕЙШН Лекарственное средство, чувствительное к комплексному соединению металл-сален, и система регуляции интракорпорального свойства для комплексного соединения металл-сален
IN2014DN03221A (de) * 2011-10-06 2015-05-22 Ihi Corp
WO2016046989A1 (ja) 2014-09-26 2016-03-31 株式会社Ihi 抗がん剤、がん細胞殺傷方法
US12303600B2 (en) 2019-06-01 2025-05-20 Hao Shang Magnetic assisted drug delivery

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US3718594A (en) * 1970-11-30 1973-02-27 Eastman Kodak Co Method of preparing magnetically responsive carrier particles
US4106488A (en) * 1974-08-20 1978-08-15 Robert Thomas Gordon Cancer treatment method
US4247406A (en) * 1979-04-23 1981-01-27 Widder Kenneth J Intravascularly-administrable, magnetically-localizable biodegradable carrier
US4345588A (en) * 1979-04-23 1982-08-24 Northwestern University Method of delivering a therapeutic agent to a target capillary bed
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
EP0093757A1 (de) * 1981-11-12 1983-11-16 Ulf SCHRÖDER Verfahren zur herstellung von magnetisch beeinflussbaren nanopartikeln für intravaskulare anwendung
JPS59122429A (ja) * 1982-12-28 1984-07-14 Japan Synthetic Rubber Co Ltd 生物学的物質の担体用磁性粒子
US4652257A (en) * 1985-03-21 1987-03-24 The United States Of America As Represented By The Secretary Of The Navy Magnetically-localizable, polymerized lipid vesicles and method of disrupting same
US4849209A (en) * 1985-06-07 1989-07-18 Cadema Medical Products, Inc. Treatment of arthritis, including rheumatoid arthritis with 166 Holmium radionuclide
US4818614A (en) * 1985-07-29 1989-04-04 Shiseido Company Ltd. Modified powder
US4690130A (en) * 1985-12-19 1987-09-01 Mirell Stuart G Electromagnetic therapy control system
US4871716A (en) * 1986-02-04 1989-10-03 University Of Florida Magnetically responsive, hydrophilic microspheres for incorporation of therapeutic substances and methods of preparation thereof
JPH01122037U (de) * 1988-02-12 1989-08-18
SU1722256A3 (ru) * 1989-11-02 1992-03-23 Viktor A Volkonskij Cпocoб пoлучehия maгhиtoупpabляemoй диcпepcии
EP0683665B1 (de) * 1993-01-29 2001-12-19 Ferx Incorporated Magnetisch reagierende zusammensetzung als träger für biologisch aktive substanzen und verfahren für ihre herstellung und verwendung

Also Published As

Publication number Publication date
EP0683665A4 (de) 1996-04-17
WO1994016683A1 (en) 1994-08-04
CA2154913C (en) 1999-10-19
EP0683665A1 (de) 1995-11-29
DE69429507D1 (de) 2002-01-31
DK0683665T3 (da) 2002-04-02
JPH08506111A (ja) 1996-07-02
US5651989A (en) 1997-07-29
US5705195A (en) 1998-01-06
EP0683665B1 (de) 2001-12-19
JP2001010978A (ja) 2001-01-16
HK1013256A1 (en) 1999-08-20
ES2165385T3 (es) 2002-03-16
CA2154913A1 (en) 1994-08-04
PT683665E (pt) 2002-05-31
AU6165394A (en) 1994-08-15
JP3176600B2 (ja) 2001-06-18
US5549915A (en) 1996-08-27
DE69429507T2 (de) 2002-05-16
JP3145120B2 (ja) 2001-03-12

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee