DK0683665T3 - Magnetisk reagerende sammensætning som bærer for biologisk aktive stoffer samt fremgangsmåder til dens fremstilling og anvendelse - Google Patents

Magnetisk reagerende sammensætning som bærer for biologisk aktive stoffer samt fremgangsmåder til dens fremstilling og anvendelse

Info

Publication number
DK0683665T3
DK0683665T3 DK94908636T DK94908636T DK0683665T3 DK 0683665 T3 DK0683665 T3 DK 0683665T3 DK 94908636 T DK94908636 T DK 94908636T DK 94908636 T DK94908636 T DK 94908636T DK 0683665 T3 DK0683665 T3 DK 0683665T3
Authority
DK
Denmark
Prior art keywords
biologically active
particles
methods
active substances
carrier
Prior art date
Application number
DK94908636T
Other languages
English (en)
Inventor
Viktor Alexeevich Volkonsky
Sergei V Chernyakov
Sergei D Dvuhsherstnov
Original Assignee
Ferx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferx Inc filed Critical Ferx Inc
Application granted granted Critical
Publication of DK0683665T3 publication Critical patent/DK0683665T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5094—Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK94908636T 1993-01-29 1994-01-26 Magnetisk reagerende sammensætning som bærer for biologisk aktive stoffer samt fremgangsmåder til dens fremstilling og anvendelse DK0683665T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1136393A 1993-01-29 1993-01-29
PCT/US1994/000892 WO1994016683A1 (en) 1993-01-29 1994-01-26 Magnetically responsive composition for carrying biologically active substances and methods of production and use

Publications (1)

Publication Number Publication Date
DK0683665T3 true DK0683665T3 (da) 2002-04-02

Family

ID=21750068

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94908636T DK0683665T3 (da) 1993-01-29 1994-01-26 Magnetisk reagerende sammensætning som bærer for biologisk aktive stoffer samt fremgangsmåder til dens fremstilling og anvendelse

Country Status (11)

Country Link
US (3) US5549915A (da)
EP (1) EP0683665B1 (da)
JP (2) JP3145120B2 (da)
AT (1) ATE210967T1 (da)
AU (1) AU6165394A (da)
CA (1) CA2154913C (da)
DE (1) DE69429507T2 (da)
DK (1) DK0683665T3 (da)
ES (1) ES2165385T3 (da)
PT (1) PT683665E (da)
WO (1) WO1994016683A1 (da)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE210967T1 (de) * 1993-01-29 2002-01-15 Ferx Inc Magnetisch reagierende zusammensetzung als träger für biologisch aktive substanzen und verfahren für ihre herstellung und verwendung
US6200547B1 (en) * 1994-01-26 2001-03-13 Ferx Incorporated Magnetically responsive compositions for carrying biologically active substances and methods of production and use
US6482436B1 (en) 1993-01-29 2002-11-19 Ferx Incorporated Magnetically responsive composition
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
US6368586B1 (en) 1996-01-26 2002-04-09 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers
US5985312A (en) * 1996-01-26 1999-11-16 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers
US7090636B2 (en) * 2000-03-31 2006-08-15 Fe Rx Incorporated Permanent magnet keeper-shield assembly
US6488615B1 (en) 2000-03-31 2002-12-03 Ferx Incorporated Permanent magnet keeper-shield assembly
WO2002069351A1 (en) * 2001-02-26 2002-09-06 University Of Utah Research Foundation Magnetic activated carbon particles for adsorption of solutes from solution
US6921283B2 (en) * 2001-08-27 2005-07-26 Trompeter Electronics, Inc. BNC connector having visual indication
FR2832598B1 (fr) * 2001-11-26 2006-01-27 Oreal Article de conditionnement et/ou d'application d'un produit
AU2003214812A1 (en) * 2002-01-09 2003-07-30 Ferx Incorporated Magnetic delivery compositions
WO2003066066A1 (en) * 2002-02-01 2003-08-14 Vanderbilt University Targeted drug delivery methods
US8097185B2 (en) * 2002-02-26 2012-01-17 University Of Utah Research Foundation Magnetic activated carbon particles for adsorption of solutes from solution
WO2004066975A1 (en) * 2002-12-18 2004-08-12 Hough Ear Institute Otologic nanotechnology
US7723311B2 (en) * 2003-06-18 2010-05-25 Nanobiomagnetics, Inc. Delivery of bioactive substances to target cells
US7344491B1 (en) 2003-11-26 2008-03-18 Nanobiomagnetics, Inc. Method and apparatus for improving hearing
US8651113B2 (en) * 2003-06-18 2014-02-18 Swr&D Inc. Magnetically responsive nanoparticle therapeutic constructs and methods of making and using
ES2264839B1 (es) * 2003-11-24 2007-10-01 Universidad De Zaragoza (Inst Denanociencia De Ar Agom. Farmacoterapia parenteral focalizada mediante el implante de imanes permanentes en los organos diana.
DE10359252A1 (de) * 2003-12-17 2005-07-28 Siemens Ag Navigierte Wärmebehandlung von Tumoren mit enzymumhüllten Eisenpartikeln
US20070100457A1 (en) * 2004-03-04 2007-05-03 Hyde Edward R Jr Paramagnetic liquid interface
CN1976681A (zh) * 2004-03-26 2007-06-06 弗尔克斯破产财产公司 可磁性靶向丝裂霉素c组合物及其使用方法
US20060024378A1 (en) * 2004-08-02 2006-02-02 Mehta Rakesh H Magnetically responsive carbon nano-structures for transporting biologically active substances, and methods relating thereto
WO2006026504A2 (en) * 2004-08-27 2006-03-09 Spherics, Inc. Mucoadhesive oral formulations of high permeability, high solubility drugs
US8568286B2 (en) * 2006-06-14 2013-10-29 Cardiac Pacemakers, Inc. Methods to position therapeutic agents using a magnetic field
EP2345974B1 (en) 2006-06-28 2014-08-06 IHI Corporation Magnetically guidable compound
US20080097606A1 (en) * 2006-10-19 2008-04-24 Cragg Andrew H Knee joint prosthesis and hyaluronate compositions for treatment of osteoarthritis
US20090169484A1 (en) 2007-12-28 2009-07-02 Ihi Corporation Iron-salen complex
JP5433155B2 (ja) * 2008-02-20 2014-03-05 株式会社Ｉｈｉ 磁性を有する薬剤、薬剤の誘導システム、並びに磁気検出装置
JP2009274962A (ja) * 2008-05-12 2009-11-26 Yoshihiro Ishikawa 鉄サレン錯体、磁性を有する薬剤、薬剤の誘導システム、並びに磁気検出装置
CN104800195A (zh) 2008-11-20 2015-07-29 株式会社Ihi 自磁性金属salen络合物
US9314602B2 (en) 2009-12-25 2016-04-19 Ihi Corporation Magnetic body and drug delivery control device using magnetic body
RU2540311C2 (ru) 2010-06-01 2015-02-10 АйЭйчАй КОРПОРЕЙШН Флуорохромный материал и способ его применения
US8740872B2 (en) 2010-10-19 2014-06-03 The Board Of Regents Of The University Of Oklahoma Magnetically-targeted treatment for cardiac disorders
US10398668B2 (en) 2010-10-19 2019-09-03 The Board Of Regents Of The University Of Oklahoma Glutamate treatment of cardiovascular disorders
US9744235B2 (en) 2010-10-19 2017-08-29 The Board Of Regents Of The University Of Oklahoma Treatment of cardiovascular disorders with targeted nanoparticles
JP2012176905A (ja) * 2011-02-25 2012-09-13 Ihi Corp 金属サレン錯体化合物
JP2012131737A (ja) * 2010-12-21 2012-07-12 Ihi Corp 金属サレン錯体化合物及びその製造方法
US9005757B2 (en) * 2010-12-21 2015-04-14 Ihi Corporation Metal-salen complex compound and method for producing the same
JP2012167067A (ja) 2011-02-15 2012-09-06 Ihi Corp 自己磁性金属サレン錯体化合物
JP5873656B2 (ja) 2011-06-13 2016-03-01 株式会社Ihi 金属サレン錯体化合物、局所麻酔薬剤及び抗悪性腫瘍薬剤
JP6017766B2 (ja) 2011-07-26 2016-11-02 株式会社Ihi 新規な金属サレン錯体化合物の抗がん剤
RU2595840C2 (ru) 2011-10-04 2016-08-27 АйЭйчАй КОРПОРЕЙШН Лекарственное средство, чувствительное к комплексному соединению металл-сален, и система регуляции интракорпорального свойства для комплексного соединения металл-сален
WO2013051363A1 (ja) * 2011-10-06 2013-04-11 株式会社Ihi 磁性組成物及びその製造方法
WO2016046989A1 (ja) 2014-09-26 2016-03-31 株式会社Ihi 抗がん剤、がん細胞殺傷方法
US12303600B2 (en) 2019-06-01 2025-05-20 Hao Shang Magnetic assisted drug delivery

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3718594A (en) * 1970-11-30 1973-02-27 Eastman Kodak Co Method of preparing magnetically responsive carrier particles
US4106488A (en) * 1974-08-20 1978-08-15 Robert Thomas Gordon Cancer treatment method
US4345588A (en) * 1979-04-23 1982-08-24 Northwestern University Method of delivering a therapeutic agent to a target capillary bed
US4247406A (en) * 1979-04-23 1981-01-27 Widder Kenneth J Intravascularly-administrable, magnetically-localizable biodegradable carrier
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
EP0093757A1 (en) * 1981-11-12 1983-11-16 Ulf SCHRÖDER Intravascularly administrable, magnetically responsive nanosphere or nanoparticle, a process for the production thereof, and the use thereof
JPS59122429A (ja) * 1982-12-28 1984-07-14 Japan Synthetic Rubber Co Ltd 生物学的物質の担体用磁性粒子
US4652257A (en) * 1985-03-21 1987-03-24 The United States Of America As Represented By The Secretary Of The Navy Magnetically-localizable, polymerized lipid vesicles and method of disrupting same
US4849209A (en) * 1985-06-07 1989-07-18 Cadema Medical Products, Inc. Treatment of arthritis, including rheumatoid arthritis with 166 Holmium radionuclide
US4818614A (en) * 1985-07-29 1989-04-04 Shiseido Company Ltd. Modified powder
US4690130A (en) * 1985-12-19 1987-09-01 Mirell Stuart G Electromagnetic therapy control system
US4871716A (en) * 1986-02-04 1989-10-03 University Of Florida Magnetically responsive, hydrophilic microspheres for incorporation of therapeutic substances and methods of preparation thereof
JPH01122037U (da) * 1988-02-12 1989-08-18
SU1722256A3 (ru) * 1989-11-02 1992-03-23 Viktor A Volkonskij Cпocoб пoлучehия maгhиtoупpabляemoй диcпepcии
ATE210967T1 (de) * 1993-01-29 2002-01-15 Ferx Inc Magnetisch reagierende zusammensetzung als träger für biologisch aktive substanzen und verfahren für ihre herstellung und verwendung

Also Published As

Publication number Publication date
EP0683665B1 (en) 2001-12-19
ATE210967T1 (de) 2002-01-15
US5651989A (en) 1997-07-29
PT683665E (pt) 2002-05-31
CA2154913C (en) 1999-10-19
US5549915A (en) 1996-08-27
DE69429507D1 (de) 2002-01-31
CA2154913A1 (en) 1994-08-04
JP2001010978A (ja) 2001-01-16
WO1994016683A1 (en) 1994-08-04
JP3176600B2 (ja) 2001-06-18
EP0683665A4 (en) 1996-04-17
HK1013256A1 (en) 1999-08-20
JP3145120B2 (ja) 2001-03-12
JPH08506111A (ja) 1996-07-02
AU6165394A (en) 1994-08-15
EP0683665A1 (en) 1995-11-29
DE69429507T2 (de) 2002-05-16
US5705195A (en) 1998-01-06
ES2165385T3 (es) 2002-03-16

Similar Documents

Publication Publication Date Title
DK0683665T3 (da) Magnetisk reagerende sammensætning som bærer for biologisk aktive stoffer samt fremgangsmåder til dens fremstilling og anvendelse
CA2317019A1 (en) Magnetically responsive composition
HU9503809D0 (en) Preparation for improving the blood supply containing hard magnetic particles
HUT74707A (en) Microcapsules containing suspensions of biologically active compounds
CA2174272A1 (en) Shielding member for radioactive substance, manufacturing method for the shielding member and apparatus for producing radioactive solution
GEP20002180B (en) Composition and Methods for Stimulating Megakaryocyte Growth and Differentiation
MY109990A (en) Microfluidised particles of atovaquone and pharmaceutical preparation thereof
ATE179185T1 (de) Verbundmaterial mit kleinem durchmesser, welches ein wasserlösliches carboxylpolysaccharid und magnetisches eisenoxid enthaltet
ZA938274B (en) Compositions of oak bark extract related synthetic compositions and method of using same
GR3015623T3 (en) Method of producing microscopic particles made of hydrolytically decomposable polymers and containing active substances.
NZ192109A (en) Analgesic effervescent powder containing paracetamol dc and metoclopramide
EP0130043A3 (en) Magnetizable adsorbents
DE3369158D1 (en) Biologically active ws 6049 substances, a process for the production thereof and their pharmaceutical compositions
CA2046308A1 (en) Radiolabeled colloid compositions, their use and process for their preparation
EP0137356A3 (en) Covalently bound heparin - antithrombin-iii complex, method for its preparation and its use for treating thromboembolism
EP0248362A3 (en) Process for the production of an active protein from a biologically inactive form
ZM2089A1 (en) Method for the production of metals,particulary ferroalloys by direct reduction and column for treating particulate materials with gas
GB1330975A (en) Apparatus for carrying out physical and chamical processes in a vortex bed of ferromagnetic particles
HU900525D0 (en) Process for the production of medical preparations for treating endotoxinemy
AU582859B2 (en) Process for preparing suspensions of powders in a liquid, intended to be injected into soils or fine or very fine materials and products obtained by this process
HU900222D0 (en) Process for giving 5b-10, 45rh-103 isotops to ferrofluidic ferric oxide, advantageous stopping vital functions of cancerous cells
UA2159A1 (uk) Спосіб утворювання магнітоуправляємої дисперсії
GB8330465D0 (en) Fr-900452 substance
JPS6480365A (en) Manufacturing porous sintered body for organism
JPS57181695A (en) Production of heterophile antibody