ATE211145T1 - Verfahren zur herstellung 17beta-carboxy steroidderivate und neue zwischenprodukte - Google Patents

Verfahren zur herstellung 17beta-carboxy steroidderivate und neue zwischenprodukte

Info

Publication number: ATE211145T1
Authority: AT; Austria
Prior art keywords: formula; vii; 17beta; producing; epoxide
Prior art date: 1994-09-06

Application number

AT95402013T

Other languages

English (en)

Inventor

Patrick Roussel

Michel Vivat

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-06

Filing date

1995-09-06

Publication date

2002-01-15

1995-09-06 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2002-01-15 Application granted granted Critical

2002-01-15 Publication of ATE211145T1 publication Critical patent/ATE211145T1/de

Links

239000013067 intermediate product Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
150000002118 epoxides Chemical class 0.000 abstract 3
-1 keto epoxide Chemical class 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 2
150000002148 esters Chemical group 0.000 abstract 2
229930194542 Keto Natural products 0.000 abstract 1
RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 1
125000001033 ether group Chemical group 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
229910000039 hydrogen halide Inorganic materials 0.000 abstract 1
239000012433 hydrogen halide Substances 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
150000002825 nitriles Chemical class 0.000 abstract 1
230000001681 protective effect Effects 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Toxicology (AREA)
Steroid Compounds (AREA)

AT95402013T 1994-09-06 1995-09-06 Verfahren zur herstellung 17beta-carboxy steroidderivate und neue zwischenprodukte ATE211145T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9410661A FR2724174B1 (fr)	1994-09-06	1994-09-06	Procede de preparation d'un derive steroide 17beta-carboxy et nouveaux intermediaires

Publications (1)

Publication Number	Publication Date
ATE211145T1 true ATE211145T1 (de)	2002-01-15

Family

ID=9466727

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95402013T ATE211145T1 (de)	1994-09-06	1995-09-06	Verfahren zur herstellung 17beta-carboxy steroidderivate und neue zwischenprodukte

Country Status (12)

Country	Link
US (4)	US5650526A (de)
EP (1)	EP0702025B1 (de)
JP (1)	JPH0881492A (de)
KR (1)	KR100394203B1 (de)
AT (1)	ATE211145T1 (de)
CA (1)	CA2157550A1 (de)
DE (1)	DE69524696T2 (de)
DK (1)	DK0702025T3 (de)
ES (1)	ES2169747T3 (de)
FR (1)	FR2724174B1 (de)
HU (2)	HU223949B1 (de)
PT (1)	PT702025E (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6410760B1 (en)	1999-10-13	2002-06-25	Pharmacia & Upjohn Company	Process to prepare androst-4-en-17-carboxylic acid
WO2019054064A1 (ja)	2017-09-12	2019-03-21	ダイキン工業株式会社	ポリジフルオロアセチレン、ポリジフルオロアセチレンの製造方法、前駆体ポリマー、成形体及び粉末

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE42606C (de) *			O. MILSTER in Remscheid, Cronenstr	Ausrückvorrichtung des Schneckengetriebes von Lastwinden
GB929983A (en)	1960-11-07	1963-06-26	British Drug Houses Ltd	6-formyl steroids
US3118882A (en) *	1961-02-16	1964-01-21	American Home Prod	Preparation of 17alpha-fluoroprogesterone and intermediates therein
US4179453A (en) *	1978-04-13	1979-12-18	Merck & Co., Inc.	Process for preparing 17β-carboxy-5-androsten-3-ones
DE3024008C2 (de) *	1980-06-24	1982-04-15	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Verfahren zur Herstellung von 17α-Hydroxy-etiocarbonsäuren
FR2486947A1 (fr) *	1980-07-15	1982-01-22	Roussel Uclaf	Nouveaux derives steroides 20-isonitriles 17(20) insatures, leur procede de preparation et leur application a la preparation des steroides 17a-hydroxy 20-ceto
US4389345A (en) *	1981-10-09	1983-06-21	G.D. Searle & Co.	3-Oxoestra-17-acetonitrile and unsaturated analogs
US4910226A (en) *	1987-04-29	1990-03-20	Smithkline Beckman Corporation	Steroid 5-alpha-reductase inhibitors
IL105050A0 (en)	1992-03-27	1993-07-08	Lilly Co Eli	Steroid derivatives
FR2700339B1 (fr) *	1993-01-14	1995-03-03	Roussel Uclaf	Nouveaux dérivés 17,20-époxydes du pregnane, leur préparation, leur application à la préparation de dérivés cortisoniques et intermédiaires.

1994
- 1994-09-06 FR FR9410661A patent/FR2724174B1/fr not_active Expired - Fee Related
1995
- 1995-08-28 US US08/519,772 patent/US5650526A/en not_active Expired - Fee Related
- 1995-09-01 JP JP7246994A patent/JPH0881492A/ja not_active Abandoned
- 1995-09-05 HU HU9801519A patent/HU223949B1/hu not_active IP Right Cessation
- 1995-09-05 CA CA002157550A patent/CA2157550A1/fr not_active Abandoned
- 1995-09-05 KR KR1019950028946A patent/KR100394203B1/ko not_active Expired - Fee Related
- 1995-09-05 HU HU9502601A patent/HU216343B/hu not_active IP Right Cessation
- 1995-09-06 ES ES95402013T patent/ES2169747T3/es not_active Expired - Lifetime
- 1995-09-06 DE DE69524696T patent/DE69524696T2/de not_active Expired - Fee Related
- 1995-09-06 PT PT95402013T patent/PT702025E/pt unknown
- 1995-09-06 EP EP95402013A patent/EP0702025B1/de not_active Expired - Lifetime
- 1995-09-06 AT AT95402013T patent/ATE211145T1/de not_active IP Right Cessation
- 1995-09-06 DK DK95402013T patent/DK0702025T3/da active
1996
- 1996-12-02 US US08/758,951 patent/US5770748A/en not_active Expired - Fee Related
1997
- 1997-11-05 US US08/964,836 patent/US5945530A/en not_active Expired - Fee Related
1998
- 1998-08-04 US US09/130,531 patent/US5919957A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HU223949B1 (hu)	2005-03-29
EP0702025A1 (de)	1996-03-20
FR2724174B1 (fr)	1997-01-17
US5945530A (en)	1999-08-31
DE69524696T2 (de)	2002-08-22
PT702025E (pt)	2002-06-28
US5650526A (en)	1997-07-22
ES2169747T3 (es)	2002-07-16
US5770748A (en)	1998-06-23
HU216343B (hu)	1999-06-28
DK0702025T3 (da)	2002-04-15
JPH0881492A (ja)	1996-03-26
KR960010680A (ko)	1996-04-20
CA2157550A1 (fr)	1996-03-07
FR2724174A1 (fr)	1996-03-08
EP0702025B1 (de)	2001-12-19
HU9502601D0 (en)	1995-10-30
KR100394203B1 (ko)	2003-10-10
DE69524696D1 (de)	2002-01-31
US5919957A (en)	1999-07-06
HUT71993A (en)	1996-03-28

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Legal Events

Date	Code	Title	Description
2002-05-15	UEP	Publication of translation of european patent specification
2005-06-15	REN	Ceased due to non-payment of the annual fee