ATE211469T1 - Benzopyrans und deren verwendung als therapeutische mittel - Google Patents

Benzopyrans und deren verwendung als therapeutische mittel

Info

Publication number: ATE211469T1
Authority: AT; Austria
Prior art keywords: benzopyrans; therapeutic agents; therapeutic; agents
Prior art date: 1994-06-10

Application number

AT95921798T

Other languages

English (en)

Inventor

Wai Ngor Chan

Helen Kate Ann Morgan

Mervyn Thompson

John Morris Evans

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-06-10

Filing date

1995-05-31

Publication date

2002-01-15

1994-06-10 Priority claimed from GB9411632A external-priority patent/GB9411632D0/en

1994-06-13 Priority claimed from GB9411798A external-priority patent/GB9411798D0/en

1995-05-31 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2002-01-15 Application granted granted Critical

2002-01-15 Publication of ATE211469T1 publication Critical patent/ATE211469T1/de

Links

150000001562 benzopyrans Chemical class 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940124597 therapeutic agent Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)

AT95921798T 1994-06-10 1995-05-31 Benzopyrans und deren verwendung als therapeutische mittel ATE211469T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB9411632A GB9411632D0 (en)	1994-06-10	1994-06-10	Novel treatment
GB9411798A GB9411798D0 (en)	1994-06-13	1994-06-13	Novel treatment
PCT/EP1995/002076 WO1995034545A1 (en)	1994-06-10	1995-05-31	Benzopyrans and their use as therapeutic agents

Publications (1)

Publication Number	Publication Date
ATE211469T1 true ATE211469T1 (de)	2002-01-15

Family

ID=26305044

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT01200801T ATE250052T1 (de)	1994-06-10	1995-05-31	Benzopyrane und deren verwendung als heilmittel
AT95921798T ATE211469T1 (de)	1994-06-10	1995-05-31	Benzopyrans und deren verwendung als therapeutische mittel

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT01200801T ATE250052T1 (de)	1994-06-10	1995-05-31	Benzopyrane und deren verwendung als heilmittel

Country Status (29)

Country	Link
US (1)	US5760074A (de)
EP (2)	EP0764157B1 (de)
JP (2)	JP3575767B2 (de)
KR (1)	KR100397721B1 (de)
CN (2)	CN1234702C (de)
AP (1)	AP714A (de)
AT (2)	ATE250052T1 (de)
AU (1)	AU701060B2 (de)
BG (1)	BG63339B1 (de)
BR (1)	BR9507980A (de)
CA (1)	CA2192480C (de)
CY (1)	CY2508B1 (de)
CZ (1)	CZ286081B6 (de)
DE (2)	DE69531801T2 (de)
DK (2)	DK1114821T3 (de)
ES (2)	ES2207590T3 (de)
FI (1)	FI120686B (de)
HK (1)	HK1039115B (de)
HU (1)	HUT76136A (de)
NO (1)	NO315651B1 (de)
NZ (1)	NZ287872A (de)
OA (1)	OA10593A (de)
PL (1)	PL188134B1 (de)
PT (2)	PT1114821E (de)
RO (1)	RO113463B1 (de)
SG (1)	SG67930A1 (de)
SI (2)	SI0764157T1 (de)
SK (1)	SK281456B6 (de)
WO (1)	WO1995034545A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20010021780A1 (en) *	1992-12-11	2001-09-13	Smithkline Beecham P.L.C.	Pharmaceutical composition containing bicyclic type compounds
GB9411635D0 (en) *	1994-06-10	1994-08-03	Smithkline Beecham Plc	Novel treatment
US6492415B2 (en) *	1996-09-18	2002-12-10	Smithkline Beecham P.L.C.	Use of benzopyranols to treat neurological disorders
GB9619492D0 (en) *	1996-09-18	1996-10-30	Smithkline Beecham Plc	Novel treatment
GB9726543D0 (en) *	1997-12-16	1998-02-11	Smithkline Beecham Plc	Novel compositions
GB9813949D0 (en) *	1998-06-29	1998-08-26	Smithkline Beecham Plc	Novel compounds
GB0028697D0 (en) *	2000-11-23	2001-01-10	S P A	Novel process
NZ561677A (en) *	2005-04-04	2011-02-25	Takeda Pharmaceutical	(S)-N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide, and its use for treating depression and anxiety neurosis
EP2307004A1 (de) *	2008-06-05	2011-04-13	Minster Research Limited	Neue behandlungen
US20110319482A1 (en) *	2008-06-05	2011-12-29	Peter Blower	Novel treatments
US20130018091A1 (en)	2009-12-03	2013-01-17	Peter Blower	Treatment of allodynia and hyperalgesia
CA2782631A1 (en)	2009-12-03	2011-06-09	Proximagen Ltd	Treatment of infectious diseases
US9499510B2 (en)	2012-07-03	2016-11-22	Proximagen Limited	Pro-drug compounds
GB201304814D0 (en) *	2013-03-15	2013-05-01	Proximagen Ltd	Pro-drug compounds
GB201322934D0 (en)	2013-12-23	2014-02-12	Proximagen Ltd	Prodrug compounds
GB201322932D0 (en) *	2013-12-23	2014-02-12	Proximagen Ltd	Pro-drug compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3479726D1 (de) *	1983-05-18	1989-10-19	Beecham Group Plc	Benzopyran derivatives.
GB9112721D0 (en) *	1991-06-13	1991-07-31	Smithkline Beecham Plc	Novel treatment
EP0673373A1 (de) *	1992-12-11	1995-09-27	Smithkline Beecham Plc	Bizyklisch verbindungen mit pharmazeutische wirkung
WO1994013657A1 (en) *	1992-12-11	1994-06-23	Smithkline Beecham Plc	Pharmaceutical composition containing bicyclic type compounds
US5536718A (en) *	1995-01-17	1996-07-16	American Cyanamid Company	Tricyclic benzazepine vasopressin antagonists

1995
- 1995-05-31 HU HU9603415A patent/HUT76136A/hu not_active Application Discontinuation
- 1995-05-31 DE DE69531801T patent/DE69531801T2/de not_active Expired - Lifetime
- 1995-05-31 CN CNB01124366XA patent/CN1234702C/zh not_active Expired - Lifetime
- 1995-05-31 NZ NZ287872A patent/NZ287872A/en not_active IP Right Cessation
- 1995-05-31 DK DK01200801T patent/DK1114821T3/da active
- 1995-05-31 AT AT01200801T patent/ATE250052T1/de active
- 1995-05-31 RO RO96-02326A patent/RO113463B1/ro unknown
- 1995-05-31 ES ES01200801T patent/ES2207590T3/es not_active Expired - Lifetime
- 1995-05-31 AU AU26727/95A patent/AU701060B2/en not_active Expired
- 1995-05-31 PT PT01200801T patent/PT1114821E/pt unknown
- 1995-05-31 PT PT95921798T patent/PT764157E/pt unknown
- 1995-05-31 WO PCT/EP1995/002076 patent/WO1995034545A1/en not_active Ceased
- 1995-05-31 JP JP50155696A patent/JP3575767B2/ja not_active Expired - Lifetime
- 1995-05-31 SK SK1587-96A patent/SK281456B6/sk not_active IP Right Cessation
- 1995-05-31 DE DE69524871T patent/DE69524871T2/de not_active Expired - Lifetime
- 1995-05-31 EP EP95921798A patent/EP0764157B1/de not_active Expired - Lifetime
- 1995-05-31 SI SI9530579T patent/SI0764157T1/xx unknown
- 1995-05-31 ES ES95921798T patent/ES2170798T3/es not_active Expired - Lifetime
- 1995-05-31 AP APAP/P/1996/000889A patent/AP714A/en active
- 1995-05-31 KR KR1019960707048A patent/KR100397721B1/ko not_active Expired - Lifetime
- 1995-05-31 AT AT95921798T patent/ATE211469T1/de active
- 1995-05-31 EP EP01200801A patent/EP1114821B1/de not_active Expired - Lifetime
- 1995-05-31 CA CA002192480A patent/CA2192480C/en not_active Expired - Lifetime
- 1995-05-31 SG SG1996008495A patent/SG67930A1/en unknown
- 1995-05-31 CN CNB951944134A patent/CN1174975C/zh not_active Expired - Lifetime
- 1995-05-31 PL PL95317579A patent/PL188134B1/pl unknown
- 1995-05-31 BR BR9507980A patent/BR9507980A/pt not_active IP Right Cessation
- 1995-05-31 DK DK95921798T patent/DK0764157T3/da active
- 1995-05-31 CZ CZ19963617A patent/CZ286081B6/cs not_active IP Right Cessation
- 1995-05-31 SI SI9530691T patent/SI1114821T1/xx unknown
- 1995-06-02 US US08/460,151 patent/US5760074A/en not_active Expired - Lifetime
1996
- 1996-12-09 NO NO19965260A patent/NO315651B1/no not_active IP Right Cessation
- 1996-12-10 OA OA60933A patent/OA10593A/en unknown
- 1996-12-10 FI FI964936A patent/FI120686B/fi not_active IP Right Cessation
- 1996-12-10 BG BG101040A patent/BG63339B1/bg unknown
2002
- 2002-01-10 HK HK02100192.4A patent/HK1039115B/en not_active IP Right Cessation
2003
- 2003-01-23 JP JP2003014984A patent/JP2003238554A/ja active Pending
2005
- 2005-03-15 CY CY0500017A patent/CY2508B1/xx unknown

Also Published As

Publication number	Publication date
NO965260D0 (no)	1996-12-09
DE69531801D1 (de)	2003-10-23
CN1154698A (zh)	1997-07-16
SK158796A3 (en)	1997-07-09
CY2508B1 (en)	2005-12-23
AU701060B2 (en)	1999-01-21
FI964936L (fi)	1997-02-06
CA2192480A1 (en)	1995-12-21
AU2672795A (en)	1996-01-05
FI964936A0 (fi)	1996-12-10
NO315651B1 (no)	2003-10-06
DE69524871D1 (de)	2002-02-07
NO965260L (no)	1997-02-06
DK0764157T3 (da)	2002-04-22
BR9507980A (pt)	1997-08-12
SI1114821T1 (en)	2004-02-29
CN1174975C (zh)	2004-11-10
RO113463B1 (ro)	1998-07-30
FI120686B (fi)	2010-01-29
PL188134B1 (pl)	2004-12-31
NZ287872A (en)	1998-05-27
PT764157E (pt)	2002-06-28
OA10593A (en)	2002-07-10
AP9600889A0 (en)	1997-01-31
CN1234702C (zh)	2006-01-04
DE69524871T2 (de)	2002-08-22
HK1001286A1 (en)	1998-06-12
PL317579A1 (en)	1997-04-14
CZ361796A3 (en)	1997-08-13
BG101040A (en)	1997-08-29
CA2192480C (en)	2007-07-24
EP0764157A1 (de)	1997-03-26
DE69531801T2 (de)	2004-07-01
PT1114821E (pt)	2004-02-27
DK1114821T3 (da)	2004-02-02
SG67930A1 (en)	1999-10-19
ES2170798T3 (es)	2002-08-16
BG63339B1 (bg)	2001-10-31
ATE250052T1 (de)	2003-10-15
ES2207590T3 (es)	2004-06-01
AP714A (en)	1998-12-23
HUT76136A (en)	1997-06-30
SK281456B6 (sk)	2001-03-12
HK1039115B (en)	2004-08-13
EP0764157B1 (de)	2002-01-02
JP2003238554A (ja)	2003-08-27
SI0764157T1 (en)	2002-06-30
HK1039115A1 (en)	2002-04-12
WO1995034545A1 (en)	1995-12-21
HU9603415D0 (en)	1997-02-28
CZ286081B6 (cs)	2000-01-12
EP1114821B1 (de)	2003-09-17
JPH10501251A (ja)	1998-02-03
KR100397721B1 (ko)	2004-04-28
EP1114821A1 (de)	2001-07-11
CN1336369A (zh)	2002-02-20
JP3575767B2 (ja)	2004-10-13
US5760074A (en)	1998-06-02

Legal Events

Date	Code	Title	Description
2002-06-15	UEP	Publication of translation of european patent specification

Publication	Publication Date	Title
DE59803292D1 (de)	2002-04-11	Triazolverbindungen und deren verwendung als dopamin-d 3-liganden
DE69302257D1 (de)	1996-05-23	Pilzhemmendes und hautheilungsförderndes Mittel
DE69529340D1 (de)	2003-02-13	Gesteuertes biopsiegerät und analysegerät
DE69617236D1 (de)	2002-01-03	N-heteroaryl-pyridinsulfonamidderivate und deren verwendung als endothelinantagonisten
EE9800459A (et)	1999-06-15	Spiro-piperidiini derivaadid ja nende kasutamine terapeutiliste toimeainetena
DE69720194D1 (de)	2003-04-30	Piperazinonphenyloxazolidinon derivate und ihre verwendung als antibakterielle mittel
DE69409591D1 (de)	1998-05-20	Kosmetische Mittel und Verwendungen
DE69631240D1 (de)	2004-02-05	Schaltvorrichtung und deren verwendung
DE69622148D1 (de)	2002-08-08	Chinazozin derivate und deren verwendung
BR9510440A (pt)	1999-08-10	Estrutura absorvente e produto absorvente descartável
DE69731161D1 (de)	2004-11-18	Kontroller und erweiterungseinheit dafür
HUT77662A (hu)	1998-07-28	Kezelt fedőlappal ellátott pelenka
DE69836008D1 (de)	2006-11-09	Zusammensetzung und behandlungsmittel
DE69627188D1 (de)	2003-05-08	Brille und brillenfassung
DE59711847D1 (de)	2004-09-16	Substituierte aza- und diazacycloheptan- und -cyclooctanverbindungen und deren verwendung
ATE186447T1 (de)	1999-11-15	Zusammensetzung und verwendung
ATE211469T1 (de)	2002-01-15	Benzopyrans und deren verwendung als therapeutische mittel
DE69517352D1 (de)	2000-07-13	Kosmetische Tensid-Präparate und deren Verwendung
ATE225342T1 (de)	2002-10-15	Benzofuran-derivate und deren verwendung
FI951060A7 (fi)	1995-09-09	Formulaatioita ja hoitomenetelmiä
EP0778847A4 (de)	1998-01-07	Immunstimulierende mittel
DE69425210D1 (de)	2000-08-17	Cumarin derivate und deren anwendung
BR9509688A (pt)	1997-09-30	Composto e composição farmacêutica
DE69600829D1 (de)	1998-11-26	Mikrobizide Zusammensetzung und deren Verwendung
DE69631632D1 (de)	2004-04-01	Schaltvorrichtung und deren verwendung