ATE211647T1 - Feste pharmazeutische zusammensetzung mit einem wasserbindenden hilfsmittel - Google Patents

Feste pharmazeutische zusammensetzung mit einem wasserbindenden hilfsmittel

Info

Publication number
ATE211647T1
ATE211647T1 AT95202770T AT95202770T ATE211647T1 AT E211647 T1 ATE211647 T1 AT E211647T1 AT 95202770 T AT95202770 T AT 95202770T AT 95202770 T AT95202770 T AT 95202770T AT E211647 T1 ATE211647 T1 AT E211647T1
Authority
AT
Austria
Prior art keywords
water
pharmaceutical composition
solid pharmaceutical
composition containing
binding agent
Prior art date
Application number
AT95202770T
Other languages
English (en)
Inventor
Haan Pieter De
Henrika Gerardin Poels-Janssen
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE211647T1 publication Critical patent/ATE211647T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT95202770T 1994-10-17 1995-10-13 Feste pharmazeutische zusammensetzung mit einem wasserbindenden hilfsmittel ATE211647T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94203017 1994-10-17

Publications (1)

Publication Number Publication Date
ATE211647T1 true ATE211647T1 (de) 2002-01-15

Family

ID=8217284

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95202770T ATE211647T1 (de) 1994-10-17 1995-10-13 Feste pharmazeutische zusammensetzung mit einem wasserbindenden hilfsmittel

Country Status (19)

Country Link
US (1) US6187339B1 (de)
EP (1) EP0707848B1 (de)
JP (1) JPH08268914A (de)
KR (1) KR100388932B1 (de)
CN (1) CN1112185C (de)
AT (1) ATE211647T1 (de)
AU (1) AU688581B2 (de)
BR (1) BR9504400A (de)
CA (1) CA2159419C (de)
DE (1) DE69524917T2 (de)
DK (1) DK0707848T3 (de)
ES (1) ES2171498T3 (de)
FI (1) FI117121B (de)
HU (1) HU221427B (de)
IL (1) IL115445A (de)
MX (1) MX9504252A (de)
PT (1) PT707848E (de)
RU (1) RU2152802C2 (de)
TR (1) TR199501246A2 (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2159419C (en) * 1994-10-17 2006-07-04 Pieter De Haan Solid pharmaceutical composition comprising an excipient capable of binding water
IL123984A (en) * 1997-04-22 2004-09-27 Akzo Nobel Nv Pharmacological dosage units containing tibolone and carrier pharmacy are acceptable
EP0955048A1 (de) * 1998-03-12 1999-11-10 Akzo Nobel N.V. Herstellung von Dosiereinheiten unter Anwendung einer Granulierung mit geringer Scherbeanspruchung
IL128818A0 (en) * 1998-03-12 2000-01-31 Akzo Nobel Nv Making dosage units using low shear granulation
CA2344686C (en) 1998-10-16 2009-04-28 Akzo Nobel N.V. High purity composition comprising (7.alpha.,17.alpha.)-17-hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn-3-one
WO2000059920A2 (en) * 1999-04-06 2000-10-12 Akzo Nobel N.V. Orally active 7.alpha.-alkyl androgens
US6979462B1 (en) 2000-10-03 2005-12-27 Mutual Pharmaceutical Co., Inc. Stabilization of solid drug formulations
US6855333B1 (en) * 2000-10-03 2005-02-15 Mutual Pharmaceutical Co., Inc. Stabilization of solid thyroid drug formulations
CA2438641A1 (en) 2001-02-15 2002-08-22 King Pharmaceuticals, Inc. Stabilized pharmaceutical and thyroid hormone compositions and method of preparation
FR2824477B1 (fr) * 2001-05-09 2005-09-09 Ethypharm Lab Prod Ethiques Granules enrobes a base d'inhibiteur de l'enzyme de conversion de l'anfiotensine, leur procede de preparation et comprimes orodispersibles contenant les granules enrobes
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
US6933380B2 (en) 2001-10-19 2005-08-23 Yung-Zip Chemical Ind. Co., Ltd. Excipients containing low residual solvent and method for producing the same
DE10159120B4 (de) * 2001-12-01 2006-08-17 Lts Lohmann Therapie-Systeme Ag Steroidhormonhaltige transdermale therapeutische Systeme enthaltend Propylenglycolmonocaprylat und seine Verwendung
IS6633A (is) * 2002-11-22 2004-05-23 Omega Farma Ehf. Samsetningar af fínasteríð töflum
CA2527686C (en) 2003-05-30 2009-11-03 Asahi Kasei Chemicals Corporation Cellulose powder
HUE031092T2 (en) * 2003-07-17 2017-07-28 Banner Life Sciences Llc Controlled release preparations
DE102004059880A1 (de) * 2004-12-10 2006-06-14 Grünenthal GmbH Stabiles, hormonhaltiges (Zwischen-)Produkt
EP2164461B1 (de) * 2007-06-06 2013-01-23 Basf Se Kau- und lutsch-tabletten
JP5627455B2 (ja) * 2007-06-06 2014-11-19 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 速崩性錠剤製造のための医薬製剤
CZ300465B6 (cs) * 2007-07-25 2009-05-27 Zentiva, A. S. Zpusob výroby komprimované farmaceutické formulace s obsahem tibolonu
DE102009012788A1 (de) * 2009-03-13 2010-09-30 J. Rettenmaier & Söhne Gmbh + Co. Kg Verpressbares Tablettenmaterial mit ölhaltigem Wirkstoff, Tablette sowie Verfahren und Vorrichtung zu deren Herstellung
HUP0900698A2 (en) 2009-11-06 2011-06-28 Richter Gedeon Nyrt Pharmaceutical compositions of enhanced stability containing drospirenone and ethynyl estradiol and process for their preparation
DE102011010437A1 (de) * 2011-02-04 2012-08-09 J. Rettenmaier & Söhne Gmbh + Co. Kg Tablettierhilfsmittel
US8633178B2 (en) 2011-11-23 2014-01-21 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
CA2947767A1 (en) 2014-05-22 2015-11-26 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2195893A (en) * 1938-07-28 1940-04-02 Nellie C Mcgann Two-part support clamp
US2965541A (en) * 1959-06-22 1960-12-20 Upjohn Co 17alpha-acetoxyprogesterone compositions for oral use and methods of using same
US3568828A (en) * 1967-03-01 1971-03-09 Squibb & Sons Inc Modified sequential oral contraceptive
NL7506407A (nl) * 1975-05-30 1976-12-02 Akzo Nv Werkwijze ter bereiding van een oraal werkzaam far- maceutisch preparaat.
JPS57142911A (en) * 1981-02-28 1982-09-03 Furointo Sangyo Kk Absorption-improving agent
JPS57165392A (en) * 1981-04-06 1982-10-12 Toyo Jozo Co Ltd Long-acting cephalexin tablet
US4544554A (en) * 1983-09-26 1985-10-01 Ortho Pharmaceutical Corporation Triphasic oral contraceptive
JPS60224616A (ja) * 1984-04-24 1985-11-09 Teijin Ltd 経鼻投与用組成物
FR2571045B1 (fr) * 1984-10-03 1987-12-11 Roquette Freres Mannitol granulaire directement compressible et son procede de fabrication
DE68916983T2 (de) * 1988-02-25 1995-01-19 Yamanouchi Europ Bv Verfahren zur Herstellung eines pharmazeutischen Granulats.
US5169645A (en) * 1989-10-31 1992-12-08 Duquesne University Of The Holy Ghost Directly compressible granules having improved flow properties
ATE113202T1 (de) * 1990-11-29 1994-11-15 Wei Ming Pharmaceutical Mfg Co Hilfsträger für direkte verpressung.
IE71203B1 (en) * 1990-12-13 1997-02-12 Akzo Nv Low estrogen oral contraceptives
IE62665B1 (en) * 1990-12-17 1995-02-22 Akzo Nv Contraceptive regimen
US5179122A (en) * 1991-02-11 1993-01-12 Eastman Kodak Company Nutritional supplement containing vitamin e
IE67345B1 (en) * 1991-03-12 1996-03-20 Akzo Nv Low dose dry pharmaceutical preparations
JPH0597672A (ja) * 1991-10-08 1993-04-20 Terumo Corp アミド誘導体含有固形製剤およびその製造方法
IT1256386B (it) * 1992-11-13 1995-12-04 Luigi Boltri Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo
BE1006990A5 (nl) * 1993-04-22 1995-02-07 Univ Gent Werkwijze en samenstelling om een aktief bestanddeel in een vaste toedieningsvorm te brengen.
EP0717618B1 (de) * 1993-09-03 2002-11-06 Smithkline Beecham Corporation Stabilisierte tablettenformulierung
CA2159419C (en) * 1994-10-17 2006-07-04 Pieter De Haan Solid pharmaceutical composition comprising an excipient capable of binding water
US6057139A (en) * 1995-06-29 2000-05-02 Mcneil-Ppc, Inc. Preblend of microcrystalline cellulose and lactase for making tablets
US5801220A (en) * 1995-11-01 1998-09-01 E.R. Squibb & Sons, Inc. Rapidly disintegrating thickening composition
US6096337A (en) * 1996-06-10 2000-08-01 Spireas; Spiridon Liquisolid systems and methods of preparing same
US5800834A (en) * 1996-06-10 1998-09-01 Spireas; Spiridon Liquisolid systems and methods of preparing same
DE19628617A1 (de) * 1996-07-16 1998-01-22 Basf Ag Direkttablettierhilfsmittel

Also Published As

Publication number Publication date
PT707848E (pt) 2002-06-28
TR199501246A2 (tr) 1996-06-21
MX9504252A (es) 1997-01-31
RU2152802C2 (ru) 2000-07-20
HU221427B (en) 2002-10-28
BR9504400A (pt) 1997-05-27
AU3426795A (en) 1996-05-02
ES2171498T3 (es) 2002-09-16
CN1112185C (zh) 2003-06-25
EP0707848B1 (de) 2002-01-09
DK0707848T3 (da) 2002-04-15
KR960013373A (ko) 1996-05-22
IL115445A (en) 1999-08-17
HU9502985D0 (en) 1995-12-28
DE69524917D1 (de) 2002-02-14
JPH08268914A (ja) 1996-10-15
EP0707848A1 (de) 1996-04-24
FI954905A0 (fi) 1995-10-16
KR100388932B1 (ko) 2003-09-19
US6187339B1 (en) 2001-02-13
CA2159419A1 (en) 1996-04-18
CN1130064A (zh) 1996-09-04
FI117121B (fi) 2006-06-30
HUT75247A (en) 1997-05-28
FI954905L (fi) 1996-04-18
AU688581B2 (en) 1998-03-12
IL115445A0 (en) 1995-12-31
DE69524917T2 (de) 2002-08-29
HK1001886A1 (en) 1998-07-17
CA2159419C (en) 2006-07-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee