ATE211653T1 - Wachstumshormon und valin enthaltende arzneimittel - Google Patents

Wachstumshormon und valin enthaltende arzneimittel

Info

Publication number: ATE211653T1
Authority: AT; Austria
Prior art keywords: valine; growth hormone; drugs containing; containing growth; dissolved
Prior art date: 1994-10-13

Application number

AT95933345T

Other languages

English (en)

Inventor

Hans Holmegaard Sorensen

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-13

Filing date

1995-10-13

Publication date

2002-01-15

1995-10-13 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

2002-01-15 Application granted granted Critical

2002-01-15 Publication of ATE211653T1 publication Critical patent/ATE211653T1/de

Links

102000018997 Growth Hormone Human genes 0.000 title abstract 2
108010051696 Growth Hormone Proteins 0.000 title abstract 2
239000000122 growth hormone Substances 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 abstract 1
KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 abstract 1
239000000654 additive Substances 0.000 abstract 1
230000000996 additive effect Effects 0.000 abstract 1
239000006172 buffering agent Substances 0.000 abstract 1
238000003776 cleavage reaction Methods 0.000 abstract 1
230000006240 deamidation Effects 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
230000003647 oxidation Effects 0.000 abstract 1
238000007254 oxidation reaction Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000007017 scission Effects 0.000 abstract 1
239000004474 valine Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Endocrinology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT95933345T 1994-10-13 1995-10-13 Wachstumshormon und valin enthaltende arzneimittel ATE211653T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/322,260 US5547696A (en)	1994-10-13	1994-10-13	Pharmaceutical formulation
PCT/DK1995/000408 WO1996011702A1 (en)	1994-10-13	1995-10-13	A pharmaceutical formulation comprising a growth hormone and valine

Publications (1)

Publication Number	Publication Date
ATE211653T1 true ATE211653T1 (de)	2002-01-15

Family

ID=23254095

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95933345T ATE211653T1 (de)	1994-10-13	1995-10-13	Wachstumshormon und valin enthaltende arzneimittel

Country Status (12)

Country	Link
US (1)	US5547696A (de)
EP (1)	EP0785795B1 (de)
JP (1)	JP4064453B2 (de)
KR (1)	KR970706840A (de)
AT (1)	ATE211653T1 (de)
AU (1)	AU699346B2 (de)
DE (1)	DE69524965T2 (de)
ES (1)	ES2171555T3 (de)
IL (1)	IL115591A (de)
PT (1)	PT785795E (de)
WO (1)	WO1996011702A1 (de)
ZA (1)	ZA958605B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK204791D0 (da) *	1991-12-20	1991-12-20	Novo Nordisk As	Hidtil ukendt farmaceutisk praeparat
US6022858A (en) *	1991-12-20	2000-02-08	Novo Nordisk A/S	Pharmaceutical formulation of human-growth hormone pretreated with zinc salt
US6673335B1 (en)	1992-07-08	2004-01-06	Nektar Therapeutics	Compositions and methods for the pulmonary delivery of aerosolized medicaments
US6582728B1 (en)	1992-07-08	2003-06-24	Inhale Therapeutic Systems, Inc.	Spray drying of macromolecules to produce inhaleable dry powders
DE69332105T2 (de)	1992-09-29	2003-03-06	Inhale Therapeutic Systems, San Carlos	Pulmonale abgabe von aktiven fragmenten des parathormons
EP0748213B1 (de)	1994-03-07	2004-04-14	Nektar Therapeutics	Verfahren und mittel zur verabreichung von insulin über die lunge
US6290991B1 (en)	1994-12-02	2001-09-18	Quandrant Holdings Cambridge Limited	Solid dose delivery vehicle and methods of making same
US20070179096A1 (en)	1996-04-24	2007-08-02	Novo Nordisk A/S	Pharmaceutical Formulation
US6565885B1 (en)	1997-09-29	2003-05-20	Inhale Therapeutic Systems, Inc.	Methods of spray drying pharmaceutical compositions
US20060165606A1 (en)	1997-09-29	2006-07-27	Nektar Therapeutics	Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en)	1997-09-29	2001-10-30	Inhale Therapeutic Systems, Inc.	Stabilized preparations for use in metered dose inhalers
WO2001085136A2 (en)	2000-05-10	2001-11-15	Alliance Pharmaceutical Corporation	Phospholipid-based powders for drug delivery
US7871598B1 (en)	2000-05-10	2011-01-18	Novartis Ag	Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en)	2000-05-10	2013-03-26	Novartis Ag	Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
KR20030038690A (ko) *	2000-08-07	2003-05-16	인헤일 테라퓨틱 시스템즈 인크.	응집이 최소화된, 흡입성 분무 건조 4-나선 다발 단백질분말
JP2005514393A (ja)	2001-12-19	2005-05-19	ネクターセラピューティクス	アミノグリコシドの肺への供給
WO2009002521A2 (en) *	2007-06-25	2008-12-31	Amgen Inc.	Compositions of specific binding agents to hepatocyte growth factor
CN116421566B (zh) *	2023-02-16	2024-10-22	高邮市人民医院	一种含聚乙二醇化重组人生长激素的制剂

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4537769A (en) *	1982-04-06	1985-08-27	American Cyanamid Company	Stabilization of influenza virus vaccine
DE3228502A1 (de) *	1982-07-30	1984-02-02	Behringwerke Ag, 3550 Marburg	Verfahren zur herstellung des c1-inaktivators und seine verwendung
JPS5967228A (ja) *	1982-10-07	1984-04-16	Green Cross Corp:The	寒冷不溶性グロブリンの凍結乾燥方法
SU1232681A1 (ru) *	1984-11-20	1986-05-23	Научно-Исследовательский Технологический Институт Аминокислот	Штамм @ @ СН-1-продуцент @ -валина
US4917685A (en) *	1986-05-16	1990-04-17	International Minerals & Chem. Corp.	Delivery device for the administration of stabilized growth promoting hormones
US5041378A (en) *	1987-08-11	1991-08-20	Cetus Corporation	Procaryotic xylose isomerase muteins
EP0303746B2 (de) *	1987-08-21	1998-12-02	Mallinckrodt Group Inc.	Stabilisierung von Wachstumshormonen
US5096885A (en) *	1988-04-15	1992-03-17	Genentech, Inc.	Human growth hormone formulation
EP0374120A3 (de) *	1988-12-13	1991-07-31	Monsanto Company	Zusammensetzung mit kontrollierter Wirkstoffabgabe von Polypeptiden
DK204791D0 (da) *	1991-12-20	1991-12-20	Novo Nordisk As	Hidtil ukendt farmaceutisk praeparat
DE69233704T2 (de) *	1991-12-20	2008-05-21	Novo Nordisk A/S	Stabilisierte pharmazeutische Formulierung, umfassend Wachstumshormon und Histidin
SE9201073D0 (sv) *	1992-04-03	1992-04-03	Kabi Pharmacia Ab	Protein formulation
EP0652766B2 (de) *	1992-07-31	2008-03-19	Genentech, Inc.	Wässrige arzneizusammensetzung, welche das menschliche wachstumshormon enthält

1994
- 1994-10-13 US US08/322,260 patent/US5547696A/en not_active Expired - Lifetime
1995
- 1995-10-12 IL IL11559195A patent/IL115591A/xx not_active IP Right Cessation
- 1995-10-12 ZA ZA958605A patent/ZA958605B/xx unknown
- 1995-10-13 PT PT95933345T patent/PT785795E/pt unknown
- 1995-10-13 DE DE69524965T patent/DE69524965T2/de not_active Expired - Lifetime
- 1995-10-13 EP EP95933345A patent/EP0785795B1/de not_active Expired - Lifetime
- 1995-10-13 ES ES95933345T patent/ES2171555T3/es not_active Expired - Lifetime
- 1995-10-13 WO PCT/DK1995/000408 patent/WO1996011702A1/en not_active Ceased
- 1995-10-13 JP JP51286196A patent/JP4064453B2/ja not_active Expired - Fee Related
- 1995-10-13 AU AU36052/95A patent/AU699346B2/en not_active Ceased
- 1995-10-13 AT AT95933345T patent/ATE211653T1/de not_active IP Right Cessation
1997
- 1997-04-14 KR KR1019970702431A patent/KR970706840A/ko not_active Abandoned

Also Published As

Publication number	Publication date
ZA958605B (en)	1996-05-14
EP0785795B1 (de)	2002-01-09
US5547696A (en)	1996-08-20
JPH10507181A (ja)	1998-07-14
WO1996011702A1 (en)	1996-04-25
AU3605295A (en)	1996-05-06
DE69524965D1 (de)	2002-02-14
AU699346B2 (en)	1998-12-03
ES2171555T3 (es)	2002-09-16
IL115591A0 (en)	1996-01-19
PT785795E (pt)	2002-07-31
JP4064453B2 (ja)	2008-03-19
EP0785795A1 (de)	1997-07-30
IL115591A (en)	2000-01-31
KR970706840A (ko)	1997-12-01
DE69524965T2 (de)	2002-08-14

Legal Events

Date	Code	Title	Description
2002-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE211653T1 (de)	2002-01-15	Wachstumshormon und valin enthaltende arzneimittel
ATE214614T1 (de)	2002-04-15	Ein wachstumshormon und isoleucin enthaltende pharmazeutische formulierung
DE69228704D1 (de)	1999-04-22	Stabilisierte pharmazeutische formulierung, die wachstumshormon und asparagin enthält
EP1197222A3 (de)	2004-02-04	Stabilisierte pharmazeutische Formulierung, die Wachstumshormon und Histidin enthält
PT1123120E (pt)	2006-10-31	Formulacao medicinal em aerossol
ATE201989T1 (de)	2001-06-15	Arzneimittel mit kontrollierter wirkstoffabgabe
BG106046A (en)	2002-05-31	Pharmaceutical compositions of ertythropoietin
HUP0102369A3 (en)	2002-05-28	Amino acid derivatives and drugs containing the same as the active ingredient
DK1014948T3 (da)	2007-09-24	Lyofiliseret farmaceutisk præparat som er beregnet til at efterligne et lægemiddel på basis af proteiner eller polypeptider
ATE213953T1 (de)	2002-03-15	Ein wachstumshormon und leucin enthaltende pharmazeutische formulierung
DE59306211D1 (de)	1997-05-22	Diphosphonsäuren und deren salze enthaltende arzneimittel
CA2185883A1 (en)	1995-09-28	The use of dimeticone as a transport and carrier system and/or drug delivery system
MX9800309A (es)	1998-07-31	Formulacion farmaceutica estabilizada que comprende una hormona del crecimiento y un peptido que comprende al menos un residuo de aminoacido basico y al menos un residuo de aminoacido acido.
AU8375891A (en)	1992-03-19	Antioxidant system based on a basic amino acid in combination with a tocopherol or derivative thereof and a nonthiolated polypeptide, and compositions containing the same
DK0626173T3 (da)	1997-05-12	Aerosolpræparat indeholdende fusafungin
MX9800358A (es)	1998-07-31	Formulacion farmaceutica estabilizada que comprende una hormona del crecimiento pretratada con zinc y opcionalmente lisina o iones calcio.
IT1254453B (it)	1995-09-25	Composizioni farmaceutiche per uso orale a base di glutatione ridotto