ATE211764T1 - Conotoxinpeptide - Google Patents

Conotoxinpeptide

Info

Publication number
ATE211764T1
ATE211764T1 AT95901691T AT95901691T ATE211764T1 AT E211764 T1 ATE211764 T1 AT E211764T1 AT 95901691 T AT95901691 T AT 95901691T AT 95901691 T AT95901691 T AT 95901691T AT E211764 T1 ATE211764 T1 AT E211764T1
Authority
AT
Austria
Prior art keywords
xaa
cys
peptides
conotoxin
alpha
Prior art date
Application number
AT95901691T
Other languages
English (en)
Inventor
Baldomero M Olivera
Lourdes J Cruz
David R Hillyard
J Michael Mcintosh
Ameurfina D Santos
Original Assignee
Univ Utah Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Utah Res Found filed Critical Univ Utah Res Found
Application granted granted Critical
Publication of ATE211764T1 publication Critical patent/ATE211764T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT95901691T 1993-10-19 1994-10-19 Conotoxinpeptide ATE211764T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/137,800 US5514774A (en) 1993-06-29 1993-10-19 Conotoxin peptides
PCT/US1994/011927 WO1995011256A1 (en) 1993-10-19 1994-10-19 Conotoxin peptides

Publications (1)

Publication Number Publication Date
ATE211764T1 true ATE211764T1 (de) 2002-01-15

Family

ID=22479095

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95901691T ATE211764T1 (de) 1993-10-19 1994-10-19 Conotoxinpeptide

Country Status (11)

Country Link
US (1) US5514774A (de)
EP (1) EP0728146B1 (de)
JP (1) JP3668880B2 (de)
AT (1) ATE211764T1 (de)
AU (1) AU681216B2 (de)
CA (1) CA2172989C (de)
DE (1) DE69429631T2 (de)
DK (1) DK0728146T3 (de)
ES (1) ES2169754T3 (de)
PT (1) PT728146E (de)
WO (1) WO1995011256A1 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589340A (en) * 1993-06-29 1996-12-31 University Of Utah Research Foundation Process and primers for identifying nucleic acids encoding A-lineage conotoxin peptides
US5595972A (en) * 1993-06-29 1997-01-21 University Of Utah Research Foundation Conotoxin peptides
US5739276A (en) * 1994-10-07 1998-04-14 University Of Utah Research Foundation Conotoxin peptides
US5670622A (en) * 1996-02-15 1997-09-23 University Of Utah Research Foundation Conotoxin peptide PIIIA
US5965534A (en) * 1995-11-22 1999-10-12 Alcon Laboratories, Inc. Use of ω-conotoxin analogs for treating retinal and optic nerve head damage
US5672682A (en) * 1996-03-18 1997-09-30 University Of Utah Research Foundation Conotoxin peptide PVIIA
WO1998020026A1 (en) * 1996-11-08 1998-05-14 University Of Utah Research Foundation Contryphan peptides
WO1998022126A1 (en) * 1996-11-18 1998-05-28 University Of Utah Research Foundation USE OF CONOTOXIN PEPTIDES ImI AND MII AS CARDIOVASCULAR AGENTS
US5935804A (en) * 1997-03-21 1999-08-10 Laine; Roger A. Method for detecting eubacteria in biological samples with catalytically inactive murein binding enzymes
US5866682A (en) * 1997-05-15 1999-02-02 University Of Utah Research Foundation Conopeptides AuIA, AuIB and AuIC
JP2001521042A (ja) * 1997-10-24 2001-11-06 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション アルファ−コノトキシンペプチドとニューロンニコチン性アセチルコリン受容体との相互作用
AU2091799A (en) 1997-12-31 1999-07-19 University Of Utah Research Foundation Uses of alpha-conotoxin peptides
AUPP627398A0 (en) * 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - II
AU6415999A (en) * 1998-10-06 2000-04-26 Cognetix, Inc. Kappa-a conopeptides and uses therefor
US20040204362A1 (en) * 1999-01-22 2004-10-14 The University Of Utah Research Foundation Alpha-conotoxin peptides
JP2003525582A (ja) * 1999-01-22 2003-09-02 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション アルファ−コノトキシンペプチド
US6855805B2 (en) 1999-01-22 2005-02-15 University Of Utah Research Foundation α-conotoxin peptides
EP1852440A1 (de) * 1999-01-29 2007-11-07 University of Utah Research Foundation Alpha-Conotoxin-Peptide
EP1147130A4 (de) * 1999-01-29 2004-09-29 Univ Utah Res Found Alpha-conotoxin-peptide
US6797808B1 (en) * 1999-01-29 2004-09-28 University Of Utah Research Foundation α-conotoxin peptides
WO2000046371A1 (en) 1999-02-04 2000-08-10 University Of Utah Research Foundation Tau-conotoxin peptides
IL148053A0 (en) 1999-08-10 2002-09-12 Uab Research Foundation Method of treating traumatic brain and spinal cord injuries and other neurogenic conditions using non-steroidal anti-inflammatory drugs and naturally occuring conotoxins
WO2002064740A2 (en) * 2001-02-09 2002-08-22 Cognetix, Inc. Cone snail peptides
AUPR409401A0 (en) * 2001-03-29 2001-04-26 University Of Melbourne, The Analgesic compound
AU2002245934B2 (en) * 2001-03-29 2008-05-01 John Down Alpha conotoxin peptides with analgesic properties
AU2003247331A1 (en) * 2002-03-15 2003-11-11 Board Of Regents, The University Of Texas System Miniprotein ligands and other polypeptides and methods for making and using same
US20040018580A1 (en) * 2002-05-10 2004-01-29 Chai Karl X. Synthetic substrates for prostasin
AU2003263853A1 (en) * 2002-08-16 2004-03-03 Board Of Regents The University Of Texas System Compositions and methods related to flavivirus envelope protein domain iii antigens
JP4095494B2 (ja) * 2003-05-30 2008-06-04 キヤノン株式会社 眼科画像処理装置及び処理方法
EP1791857A4 (de) * 2004-09-09 2009-04-08 Univ Singapore Konformationswechsel in der toxinfaltung und verwendungen dafür
US7387997B2 (en) * 2004-11-09 2008-06-17 University Of Utah α-conotoxin MII analogues
SG10201601789TA (en) 2011-03-16 2016-04-28 Amgen Inc Potent And Selective Inhibitors Of Nav1.3 And Nav1.7
US10344060B2 (en) 2013-03-12 2019-07-09 Amgen Inc. Potent and selective inhibitors of Nav1.7
US9636418B2 (en) 2013-03-12 2017-05-02 Amgen Inc. Potent and selective inhibitors of NAV1.7
MX367858B (es) * 2013-05-31 2019-09-09 Univ Utah Res Found Péptidos de conotoxina, composiciones farmacéuticas y usos de los mismos.
CN103554226B (zh) * 2013-10-30 2016-02-03 南京工业大学 一种α-芋螺毒素MI的全固相合成方法
US20170209553A1 (en) 2016-01-22 2017-07-27 Transderm, Inc. Delivery of botulinum with microneedle arrays
CN110981967B (zh) * 2019-11-22 2022-10-14 中国海洋大学 α-芋螺毒素Mr1.1的二聚体、合成方法及应用
CA3179793A1 (en) * 2020-04-09 2021-10-14 Glo Pharma, Inc. Peptide compositions and methods for inhibiting nicotinic acetylcholine receptor activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051403A (en) * 1989-11-22 1991-09-24 Neurex Corporation Method of treating ischemia-related neuronal damage
US5231011A (en) * 1991-04-18 1993-07-27 University Of Utah Segregated folding determinants for small disulfide-rich peptides
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
US5432155A (en) * 1993-06-29 1995-07-11 The Salk Institute For Biological Studies Conotoxins I

Also Published As

Publication number Publication date
EP0728146B1 (de) 2002-01-09
DK0728146T3 (da) 2002-04-22
PT728146E (pt) 2002-05-31
JPH10509415A (ja) 1998-09-14
US5514774A (en) 1996-05-07
JP3668880B2 (ja) 2005-07-06
AU1083195A (en) 1995-05-08
DE69429631D1 (en) 2002-02-14
AU681216B2 (en) 1997-08-21
CA2172989A1 (en) 1995-04-27
DE69429631T2 (de) 2002-09-12
WO1995011256A1 (en) 1995-04-27
EP0728146A1 (de) 1996-08-28
CA2172989C (en) 2002-09-17
ES2169754T3 (es) 2002-07-16
EP0728146A4 (de) 1998-08-19

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee