ATE214601T1 - Rekombinantes vielwertiges m-protein-vakzin - Google Patents
Rekombinantes vielwertiges m-protein-vakzinInfo
- Publication number
- ATE214601T1 ATE214601T1 AT93922201T AT93922201T ATE214601T1 AT E214601 T1 ATE214601 T1 AT E214601T1 AT 93922201 T AT93922201 T AT 93922201T AT 93922201 T AT93922201 T AT 93922201T AT E214601 T1 ATE214601 T1 AT E214601T1
- Authority
- AT
- Austria
- Prior art keywords
- protein vaccine
- value
- vaccine
- recombinant multi
- recombinant
- Prior art date
Links
- 229940023143 protein vaccine Drugs 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 206010061372 Streptococcal infection Diseases 0.000 abstract 1
- 241001505901 Streptococcus sp. 'group A' Species 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 201000003068 rheumatic fever Diseases 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94595492A | 1992-09-16 | 1992-09-16 | |
| PCT/US1993/008703 WO1994006421A1 (en) | 1992-09-16 | 1993-09-15 | Recombinant multivalent m protein vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE214601T1 true ATE214601T1 (de) | 2002-04-15 |
Family
ID=25483752
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93922201T ATE214601T1 (de) | 1992-09-16 | 1993-09-15 | Rekombinantes vielwertiges m-protein-vakzin |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6063386A (de) |
| EP (1) | EP0625043B1 (de) |
| AT (1) | ATE214601T1 (de) |
| AU (1) | AU5128493A (de) |
| CA (1) | CA2123579C (de) |
| DE (1) | DE69331733T2 (de) |
| DK (1) | DK0625043T3 (de) |
| ES (1) | ES2170075T3 (de) |
| IL (1) | IL107025A0 (de) |
| WO (1) | WO1994006421A1 (de) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6737521B1 (en) * | 1990-05-11 | 2004-05-18 | The Rockefeller University | Delivery and expression of a hybrid surface protein on the surface of gram positive bacteria |
| IL107026A0 (en) * | 1992-09-16 | 1993-12-28 | Univ Tennessee Res Corp | Antigen of hybrid m protein and carrier for group a streptococcal vaccine |
| DE69331733T2 (de) * | 1992-09-16 | 2002-08-22 | The University Of Tennessee Research Corp., Knoxville | Rekombinantes vielwertiges m-protein-vakzin |
| WO1996009395A2 (de) * | 1994-09-21 | 1996-03-28 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Arzneimittel zur prophylaxe und behandlung von und diagnostika zur erkennung von autoimmunkrankheiten und viralen erkrankungen |
| AUPM885194A0 (en) * | 1994-10-14 | 1994-11-10 | Council Of The Queensland Institute Of Medical Research, The | Synthetic peptides and vaccines comprising same |
| US6287574B1 (en) * | 1995-03-17 | 2001-09-11 | Biochem Pharma Inc. | Proteinase K resistant surface protein of neisseria meningitidis |
| US6355255B1 (en) | 1998-12-07 | 2002-03-12 | Regents Of The University Of Minnesota | Streptococcal C5a peptidase vaccine |
| US5846547A (en) * | 1996-01-22 | 1998-12-08 | Regents Of The University Of Minnesota | Streptococcal C5a peptidase vaccine |
| US6716433B1 (en) | 1997-09-12 | 2004-04-06 | University Of Tennessee Research Foundation | Group a streptococcal vaccines |
| EP1801217A1 (de) * | 1997-09-12 | 2007-06-27 | The University of Tennessee Research Foundation | Streptokokken-Impfstoffgruppe |
| ATE349527T1 (de) * | 1997-09-12 | 2007-01-15 | Univ Tennessee Res Foundation | Gruppe a streptokokken-impfstoff |
| US7390619B1 (en) | 1998-02-11 | 2008-06-24 | Maxygen, Inc. | Optimization of immunomodulatory properties of genetic vaccines |
| US6541011B2 (en) * | 1998-02-11 | 2003-04-01 | Maxygen, Inc. | Antigen library immunization |
| AU762100B2 (en) * | 1998-12-22 | 2003-06-19 | University Of Tennessee Research Corporation, The | Protective antigen of group A Streptococci (SPA) |
| US7063850B1 (en) | 1998-12-22 | 2006-06-20 | University Of Tennessee Research Foundation | Protective antigen of group A Streptococci |
| US7256265B2 (en) | 1999-12-03 | 2007-08-14 | Regents Of The University Of Minnesota | Streptococcal C5a peptidase vaccine |
| DK1294771T3 (da) * | 2000-06-12 | 2008-12-15 | Univ Saskatchewan | Kimært GapC-protein fra Streptococcus og anvendelse deraf til vaccinering og diagnosticering |
| US7160547B2 (en) | 2000-10-10 | 2007-01-09 | University Of Tennessee Research Corporation | Streptococcal streptolysin S vaccines |
| WO2002057315A2 (en) * | 2000-10-10 | 2002-07-25 | University Of Tennessee Research Corporation | Streptococcal streptolysin s vaccines |
| CA2447017A1 (en) * | 2001-05-15 | 2002-11-21 | Shire Biochem Inc. | Moraxella(branhamella) catarrhalis antigens |
| AU2011232787B2 (en) * | 2001-05-18 | 2013-05-02 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention, Technology Transfer Office | Peptide vaccines against group A streptococci |
| WO2002094851A2 (en) * | 2001-05-18 | 2002-11-28 | The Government Of The United States Of America, Asrepresented By The Secretary, Department Of Healthand Human Services, Centers For Disease Control And Prevention, Technology Transfer Office | Peptide vaccines against group a streptococci |
| AU2008203277B2 (en) * | 2001-05-18 | 2011-07-07 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention, Technology Transfer Office | Peptide vaccines against group A streptococci |
| US7270827B2 (en) | 2001-10-26 | 2007-09-18 | University Of Tennessee Research Foundation | Multivalent streptococcal vaccine compositions and methods for use |
| US7476390B2 (en) | 2002-02-26 | 2009-01-13 | Maxygen, Inc. | Flavivirus antigens |
| US7255867B2 (en) * | 2002-11-15 | 2007-08-14 | Id Biomedical Corporation Of Quebec | Vaccine |
| US20040151737A1 (en) * | 2003-02-05 | 2004-08-05 | University Of Tennessee | Streptococcal serum opacity factors and fibronectin-binding proteins and peptides thereof for the treatment and detection of streptococcal infection |
| WO2005017093A2 (en) * | 2003-08-15 | 2005-02-24 | Id Biomedical Corporation | Polypeptides of streptococcus pyogenes |
| EP1864996A1 (de) * | 2006-06-06 | 2007-12-12 | Helmholtz-Zentrum für Infektionsforschung GmbH | Peptid das mit rheumatischem Fieber verbunden ist und dessen Verwendung als diagnostischer Marker. |
| US9289485B2 (en) * | 2006-11-30 | 2016-03-22 | Luiza Guilherme Guglielmi | Therapeutic application of S. pyogenes C-terminal peptide |
| BRPI0604997A (pt) * | 2006-11-30 | 2007-05-22 | Fundacao Zerbini | vacina contra o estreptococo beta hemolìtico do grupo a, e respectivo processo de obtenção |
| SI2144924T1 (sl) * | 2007-04-16 | 2016-12-30 | Minervax Aps | Cepivo s fuzijskimi beljakovinami |
| EA017887B1 (ru) * | 2007-08-02 | 2013-03-29 | Байондвакс Фармасьютикалз Лтд. | Полимерные мультиэпитопные вакцины против гриппа |
| MX2011004755A (es) | 2008-11-05 | 2011-10-10 | Wyeth Llc | Composicion inmunogenica multicomponente para la prevencion de enfermedad estreptococica beta-hemolitica (bhs). |
| WO2012114323A1 (en) | 2011-02-22 | 2012-08-30 | Biondvax Pharmaceuticals Ltd. | Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines |
| AU2012271336B2 (en) | 2011-06-17 | 2017-03-02 | University Of Tennessee Research Foundation | Group A streptococcus multivalent vaccine |
| WO2014124446A1 (en) | 2013-02-11 | 2014-08-14 | University Of Tennessee Research Foundation | Group a streptococcal m-related proteins and methods of use |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4284537A (en) * | 1980-07-03 | 1981-08-18 | The United States Of America As Represented By The Department Of Health And Human Services | Conjugate of streptococcal M protein peptide vaccine |
| US4597967A (en) * | 1982-07-27 | 1986-07-01 | The University Of Tennessee Research Corp. | Synthetic polypeptide fragments |
| US4454121A (en) * | 1982-07-27 | 1984-06-12 | The University Of Tennessee Research Corporation | Synthetic peptides corresponding to antigenic determinants of the M protein of Streptococcus pyogenes |
| US4521334A (en) * | 1982-07-27 | 1985-06-04 | The University Of Tennesse Research Corporation | Synthetic polypeptide fragments |
| US4919930A (en) * | 1983-06-10 | 1990-04-24 | University Of Tennessee Research Corporation | Synthetic M proteins-streptococci type 5 |
| US4784948A (en) * | 1983-08-10 | 1988-11-15 | The Rockefeller University | Production of streptococcal m protein immunogens and molecular probes |
| US4705684A (en) * | 1985-05-31 | 1987-11-10 | The University Of Tennessee Research Corporation | Synthetic M proteins - streptococci type 6 |
| US5124153A (en) * | 1987-08-24 | 1992-06-23 | University Of Tennessee Research Corp. | Therapeutic compositions against streptococcal infections, transformed hosts, methods of immunization and genetically engineered products |
| WO1993021220A1 (en) * | 1992-04-08 | 1993-10-28 | The Council Of The Queensland Institute Of Medical Research | Synthetic peptides useful in a vaccine against and in the diagnosis of streptococcal infection |
| DE69331733T2 (de) * | 1992-09-16 | 2002-08-22 | The University Of Tennessee Research Corp., Knoxville | Rekombinantes vielwertiges m-protein-vakzin |
-
1993
- 1993-09-15 DE DE69331733T patent/DE69331733T2/de not_active Expired - Fee Related
- 1993-09-15 CA CA002123579A patent/CA2123579C/en not_active Expired - Fee Related
- 1993-09-15 AT AT93922201T patent/ATE214601T1/de not_active IP Right Cessation
- 1993-09-15 WO PCT/US1993/008703 patent/WO1994006421A1/en not_active Ceased
- 1993-09-15 ES ES93922201T patent/ES2170075T3/es not_active Expired - Lifetime
- 1993-09-15 EP EP93922201A patent/EP0625043B1/de not_active Expired - Lifetime
- 1993-09-15 AU AU51284/93A patent/AU5128493A/en not_active Abandoned
- 1993-09-15 IL IL107025A patent/IL107025A0/xx unknown
- 1993-09-15 DK DK93922201T patent/DK0625043T3/da active
-
1997
- 1997-09-15 US US08/937,271 patent/US6063386A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1994006421A1 (en) | 1994-03-31 |
| DE69331733D1 (de) | 2002-04-25 |
| EP0625043A1 (de) | 1994-11-23 |
| AU5128493A (en) | 1994-04-12 |
| DE69331733T2 (de) | 2002-08-22 |
| CA2123579A1 (en) | 1994-03-31 |
| ES2170075T3 (es) | 2002-08-01 |
| DK0625043T3 (da) | 2002-04-22 |
| EP0625043B1 (de) | 2002-03-20 |
| IL107025A0 (en) | 1993-12-28 |
| CA2123579C (en) | 2005-05-10 |
| EP0625043A4 (en) | 1997-05-21 |
| US6063386A (en) | 2000-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |