ATE215095T1 - Immunologisches testverfahren zur quantifizierung von peg-modifiziertem humanem granulozyten- kolonie-stimulierender-faktor - Google Patents

Immunologisches testverfahren zur quantifizierung von peg-modifiziertem humanem granulozyten- kolonie-stimulierender-faktor

Info

Publication number
ATE215095T1
ATE215095T1 AT95119829T AT95119829T ATE215095T1 AT E215095 T1 ATE215095 T1 AT E215095T1 AT 95119829 T AT95119829 T AT 95119829T AT 95119829 T AT95119829 T AT 95119829T AT E215095 T1 ATE215095 T1 AT E215095T1
Authority
AT
Austria
Prior art keywords
stimulating factor
human granulocyte
granulocyte colony
modified human
peg
Prior art date
Application number
AT95119829T
Other languages
English (en)
Inventor
Nobuo Hanai
Akiko Furuya
Motoo Yamasaki
Satoshi Kobayashi
Takashi Kuwabara
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Application granted granted Critical
Publication of ATE215095T1 publication Critical patent/ATE215095T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243Colony Stimulating Factors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT95119829T 1994-12-15 1995-12-15 Immunologisches testverfahren zur quantifizierung von peg-modifiziertem humanem granulozyten- kolonie-stimulierender-faktor ATE215095T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP31176394A JP3708151B2 (ja) 1994-12-15 1994-12-15 Peg化したヒト顆粒球コロニー刺激因子の定量法

Publications (1)

Publication Number Publication Date
ATE215095T1 true ATE215095T1 (de) 2002-04-15

Family

ID=18021197

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95119829T ATE215095T1 (de) 1994-12-15 1995-12-15 Immunologisches testverfahren zur quantifizierung von peg-modifiziertem humanem granulozyten- kolonie-stimulierender-faktor

Country Status (6)

Country Link
US (1) US5939280A (de)
EP (1) EP0721958B1 (de)
JP (1) JP3708151B2 (de)
AT (1) ATE215095T1 (de)
DE (1) DE69526056T2 (de)
ES (1) ES2173146T3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030053982A1 (en) 1994-09-26 2003-03-20 Kinstler Olaf B. N-terminally chemically modified protein compositions and methods
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
JP2002540065A (ja) * 1999-01-29 2002-11-26 アムジェン インコーポレーテッド Gcsfコンジュゲート
SI1157037T1 (en) * 1999-01-29 2003-12-31 F. Hoffmann-La Roche Ag Gcsf conjugates
KR100735784B1 (ko) * 2005-07-20 2007-07-06 재단법인 목암생명공학연구소 인간 과립구콜로니자극인자 변이체 및 이의 화학적 접합물

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB331186A (en) * 1929-03-18 1930-06-18 Bataafsche Petroleum A process for the manufacture of valuable products from ethylene and/or its homologues
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4778752A (en) * 1983-10-11 1988-10-18 Scripps Clinic And Research Foundation Receptors specific for hapten-modified self proteins
NZ218336A (en) * 1985-12-09 1991-08-27 Kirin Amgen Inc Monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (hpg-csf)
JP2618618B2 (ja) * 1988-03-04 1997-06-11 協和醗酵工業株式会社 抗g−csf誘導体、nd28モノクローナル抗体
US5362853A (en) * 1986-12-23 1994-11-08 Kyowa Hakko Kogyo Co., Ltd. Polypeptide derivatives of human granulocyte colony stimulating factor
US5214132A (en) * 1986-12-23 1993-05-25 Kyowa Hakko Kogyo Co., Ltd. Polypeptide derivatives of human granulocyte colony stimulating factor
US5194592A (en) * 1986-12-23 1993-03-16 Kyowa Hakko Kogyo Co. Ltd. Monoclonal antibodies to novel polypeptide derivatives of human granulocyte colony stimulating factor
JPS63180860A (ja) * 1987-01-22 1988-07-25 Kyowa Hakko Kogyo Co Ltd 抗g−csfモノクロ−ナル抗体
EP0401384B1 (de) * 1988-12-22 1996-03-13 Kirin-Amgen, Inc. Chemisch modifizierte granulocytenkolonie erregender faktor
JP3051145B2 (ja) * 1990-08-28 2000-06-12 住友製薬株式会社 新規なポリエチレングリコール誘導体修飾ペプチド
US6565841B1 (en) * 1991-03-15 2003-05-20 Amgen, Inc. Pulmonary administration of granulocyte colony stimulating factor
US5336782A (en) * 1991-04-24 1994-08-09 Kuraray Co., Ltd. Long chain carboxylic acid imide ester
JPH05115197A (ja) * 1991-10-21 1993-05-07 Fanuc Ltd リラクタンスモータ用ロータリエンコーダと駆動装置
JPH05115297A (ja) * 1991-10-29 1993-05-14 Otsuka Pharmaceut Co Ltd ヒトg−csf抗体及びヒトg−csfの測定法
US5581476A (en) * 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
US5298410A (en) * 1993-02-25 1994-03-29 Sterling Winthrop Inc. Lyophilized formulation of polyethylene oxide modified proteins with increased shelf-life
US5605976A (en) * 1995-05-15 1997-02-25 Enzon, Inc. Method of preparing polyalkylene oxide carboxylic acids
US5536382A (en) * 1994-05-23 1996-07-16 Advanced Molecular Systems, Inc. Capillary electrophoresis assay method useful for the determination of constituents of a clinical sample
US5593666A (en) * 1994-08-16 1997-01-14 The University Of Tennessee Research Corp. Methods and compositions for treating thrombocytopenia

Also Published As

Publication number Publication date
ES2173146T3 (es) 2002-10-16
JPH08165300A (ja) 1996-06-25
EP0721958A2 (de) 1996-07-17
DE69526056D1 (de) 2002-05-02
US5939280A (en) 1999-08-17
EP0721958A3 (de) 1996-12-18
DE69526056T2 (de) 2003-04-03
JP3708151B2 (ja) 2005-10-19
EP0721958B1 (de) 2002-03-27

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ATE215095T1 (de) Immunologisches testverfahren zur quantifizierung von peg-modifiziertem humanem granulozyten- kolonie-stimulierender-faktor
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