ATE215992T1 - Isolierung fötaler erythrozyten - Google Patents

Isolierung fötaler erythrozyten

Info

Publication number
ATE215992T1
ATE215992T1 AT94907836T AT94907836T ATE215992T1 AT E215992 T1 ATE215992 T1 AT E215992T1 AT 94907836 T AT94907836 T AT 94907836T AT 94907836 T AT94907836 T AT 94907836T AT E215992 T1 ATE215992 T1 AT E215992T1
Authority
AT
Austria
Prior art keywords
erythrocytes
maternal blood
nfes
isolation
maternal
Prior art date
Application number
AT94907836T
Other languages
English (en)
Inventor
Simon B Goldbard
Original Assignee
Vysis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vysis Inc filed Critical Vysis Inc
Application granted granted Critical
Publication of ATE215992T1 publication Critical patent/ATE215992T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002—Partitioning blood components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Ecology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT94907836T 1993-01-22 1994-01-18 Isolierung fötaler erythrozyten ATE215992T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/007,479 US5457024A (en) 1993-01-22 1993-01-22 Isolation of fetal erythrocytes
PCT/US1994/000644 WO1994017209A1 (en) 1993-01-22 1994-01-18 Isolation of fetal erythrocytes

Publications (1)

Publication Number Publication Date
ATE215992T1 true ATE215992T1 (de) 2002-04-15

Family

ID=21726425

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94907836T ATE215992T1 (de) 1993-01-22 1994-01-18 Isolierung fötaler erythrozyten

Country Status (8)

Country Link
US (1) US5457024A (de)
EP (1) EP0681614B1 (de)
JP (1) JPH08505777A (de)
AT (1) ATE215992T1 (de)
AU (1) AU6125094A (de)
CA (1) CA2154460A1 (de)
DE (1) DE69430365T2 (de)
WO (1) WO1994017209A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629147A (en) * 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
NZ292756A (en) * 1994-08-31 1998-10-28 Activated Cell Therapy Inc Cell separation apparatus and method using centrifugation and density mediums
GB9417912D0 (en) * 1994-09-06 1994-10-26 Univ Leeds Diagnostic apparatus
US5662813A (en) 1994-10-21 1997-09-02 Bioseparations, Inc. Method for separation of nucleated fetal erythrocytes from maternal blood samples
GB9422504D0 (en) * 1994-11-08 1995-01-04 Robertson Patricia M B Blood testing
JPH11502106A (ja) * 1995-03-08 1999-02-23 バイオセパレーションズ・インコーポレーテッド 少数細胞集団を濃縮する方法
US6153186A (en) * 1995-09-15 2000-11-28 Duke University Medical Center Red blood cells loaded with S-nitrosothiol and uses therefor
US5731156A (en) * 1996-10-21 1998-03-24 Applied Imaging, Inc. Use of anti-embryonic hemoglobin antibodies to identify fetal cells
JP2001506005A (ja) * 1996-12-11 2001-05-08 ナイコメッド・アマーシャム・ピーエルシー 細胞の選択的溶解
US5962234A (en) * 1997-10-20 1999-10-05 Applied Imaging Corporation Use of anti-embryonic epsilon hemoglobin antibodies to identify fetal cells
US6733967B1 (en) 1998-04-21 2004-05-11 Interleukin Genetics, Inc. Fetal testing for prediction of low birth weight
FR2781055B1 (fr) * 1998-07-09 2000-10-13 Immunotech Sa Reactif et methode pour la permeabilisation et l'identification des erythrocytes
US20040152190A1 (en) * 2001-05-31 2004-08-05 Masaya Sumita Method of separating and concentrating cells for kidney regfneration
JP4229237B2 (ja) * 2001-12-11 2009-02-25 株式会社ネーテック 血液細胞分離システム
EP2359689B1 (de) 2002-09-27 2015-08-26 The General Hospital Corporation Mikrofluid-Vorrichtung zur Zelltrennung, sowie Verwendung derselben
CA2445204C (en) 2002-10-16 2014-08-12 Streck Laboratories, Inc. Method and device for collecting and preserving cells for analysis
US20050208501A1 (en) * 2004-03-16 2005-09-22 Ambion, Inc. Process and reagents for extraction of RNA from fractionated blood leukocytes
US20060252087A1 (en) * 2005-01-18 2006-11-09 Biocept, Inc. Recovery of rare cells using a microchannel apparatus with patterned posts
US8158410B2 (en) 2005-01-18 2012-04-17 Biocept, Inc. Recovery of rare cells using a microchannel apparatus with patterned posts
CN103382434B (zh) 2005-01-18 2016-05-25 生物概念股份有限公司 利用含排列成图案的立柱的微通道分离细胞
US20090136982A1 (en) * 2005-01-18 2009-05-28 Biocept, Inc. Cell separation using microchannel having patterned posts
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
EP1874920A4 (de) * 2005-04-05 2009-11-04 Cellpoint Diagnostics Vorrichtungen und verfahren zur anreicherung und veränderung zirkulierender tumorzellen und anderer partikel
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US7695956B2 (en) * 2006-01-12 2010-04-13 Biocept, Inc. Device for cell separation and analysis and method of using
WO2010078194A1 (en) * 2008-12-30 2010-07-08 Streck, Inc. Method for screening blood using a preservative that may be in a substantially solid state form
DE202010018561U1 (de) 2009-01-21 2017-08-28 Streck Inc. Blutsammelröhrchen
US11634747B2 (en) 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
NO2398912T3 (de) 2009-02-18 2018-02-10
BR112012018166A2 (pt) 2010-01-21 2015-09-15 Biocep Ltd separação magnética de células raras.
US8774488B2 (en) 2010-03-11 2014-07-08 Cellscape Corporation Method and device for identification of nucleated red blood cells from a maternal blood sample
US9956281B2 (en) 2011-05-04 2018-05-01 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
US10091984B2 (en) 2013-07-24 2018-10-09 Streck, Inc. Compositions and methods for stabilizing circulating tumor cells
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
WO2018022991A1 (en) 2016-07-29 2018-02-01 Streck, Inc. Suspension composition for hematology analysis control
CN115119829B (zh) 2017-10-19 2024-07-12 斯特雷克股份有限公司 用于胞外囊泡的溶血和凝血调节以及稳定化的组合物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4185964A (en) * 1977-02-08 1980-01-29 Central Laboratories of Associated Maryland Pathologists, Ltd. Lysing reagent
US4190535A (en) * 1978-02-27 1980-02-26 Corning Glass Works Means for separating lymphocytes and monocytes from anticoagulated blood
US4255256A (en) * 1978-12-13 1981-03-10 Antonio Ferrante Medium for the separation of human blood leucocytes
US4861705A (en) * 1983-01-31 1989-08-29 Yeda Research And Development Company, Ltd. Method for removing components of biological fluids
US4675286A (en) * 1985-01-28 1987-06-23 Aspen Diagnostics, Inc. Fetal cell separation and testing
US4888278A (en) * 1985-10-22 1989-12-19 University Of Massachusetts Medical Center In-situ hybridization to detect nucleic acid sequences in morphologically intact cells
US4927750A (en) * 1986-04-09 1990-05-22 Jeanette Simpson Cell separation process
US4976861A (en) * 1987-10-20 1990-12-11 Pall Corporation Method for determining the wetting characteristic of a porous medium
US4925572A (en) * 1987-10-20 1990-05-15 Pall Corporation Device and method for depletion of the leukocyte content of blood and blood components
US4923620A (en) * 1987-10-20 1990-05-08 Pall Corporation Device for depletion of the leukocyte content of blood and blood components
US4880548A (en) * 1988-02-17 1989-11-14 Pall Corporation Device and method for separating leucocytes from platelet concentrate
ES2112833T3 (es) * 1988-12-06 1998-04-16 Flinders Technologies Pty Ltd Aislamiento de celulas fetales a partir de sangre materna para permitir el diagnostico prenatal.
JPH05501612A (ja) * 1989-11-13 1993-03-25 チルドレンズ・メデイカル・センター・コーポレーシヨン 胎児ｄｎａ単離および検出のための非侵入性方法
US5153117A (en) * 1990-03-27 1992-10-06 Genetype A.G. Fetal cell recovery method
CA2081203A1 (en) * 1990-04-23 1991-10-24 Ronald J. Berenson Method for enriching fetal cells from maternal blood
BR9306867A (pt) * 1992-07-17 1998-12-08 Aprogenex Inc Enriquecimento e identificação de células fetais do sangue materno para a hibridização in situ
US5275933A (en) * 1992-09-25 1994-01-04 The Board Of Trustees Of The Leland Stanford Junior University Triple gradient process for recovering nucleated fetal cells from maternal blood

Also Published As

Publication number Publication date
WO1994017209A1 (en) 1994-08-04
DE69430365T2 (de) 2002-11-21
AU6125094A (en) 1994-08-15
EP0681614B1 (de) 2002-04-10
EP0681614A4 (de) 1997-06-04
CA2154460A1 (en) 1994-08-04
DE69430365D1 (de) 2002-05-16
US5457024A (en) 1995-10-10
JPH08505777A (ja) 1996-06-25
EP0681614A1 (de) 1995-11-15

Similar Documents

Publication Publication Date Title
DE69430365D1 (de) Isolierung fötaler erythrozyten
Gorus et al. A rapid method for the fractionation of human spermatozoa according to their progressive motility
GB9518156D0 (en) Method of isolating cells
CA2469878A1 (en) Blood cell separating system
AU2487095A (en) Non-invasive method for isolation and detection of foetal DNA
KR100213805B1 (en) Glycoalkaloids
CA2127172A1 (en) Analyte Detection Device and Process
SE9203320D0 (sv) A method of processing nucleic acid samples
IL146660A0 (en) Method for separating cells using immunorosettes
DE69332926D1 (de) Kontinuierliches zentrifugationsverfahren zum abtrennen von biologischen komponenten aus heterogenen zellpopulationen
PT995097E (pt) Dispositivo e processo para isolar material celular de uma estrutura de tecido e/ou de um liquido
DK0521909T3 (da) Fremgangsmåde til udvinding af fosterceller
ES2196116T3 (es) Dosificado de homocisteina.
UA29421C2 (uk) Спосіб виділення фактора vііі з інших білків в плазмі крові
DK0564494T3 (da) Testmetode og reagenssæt dertil
GB2326943B (en) Detection of fetal red cells in maternal blood
IT8422059A0 (it) Dispositivo d'analisi, destinata a raccogliere una frazione di un campione di liquido per reazione e analisi.
AU2284399A (en) Method for transforming plasma and implementing device
WO2001049821A3 (fr) Lignees des lymphocytes t cd4 specifiques de type th1 et procede pour leur induction ex vivo
EP0325413A3 (de) Verfahren und Vorrichtung zur Plasma-Trennung von Rotzellen
AU7913887A (en) Method for the removal of undesired cells from human lymphocyte populations, application of the method in monoclonal antibody production and kit therefor
ATE228026T1 (de) Methode zur erreicherung von populationen seltener zellen
ATE180893T1 (de) Chromatographiematerial
Ganguly et al. Evidence for multiple mechanisms of interaction between wheat germ agglutinin and human platelets
WO1997030354A3 (en) Foetal cell analysis

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties