ATE216403T1 - Verfahren zur solubisierung des pulmonnären oberflächeraktiven peptides - Google Patents

Verfahren zur solubisierung des pulmonnären oberflächeraktiven peptides

Info

Publication number: ATE216403T1
Authority: AT; Austria
Prior art keywords: solubizing; active peptide; pulmonary surface; protein; pulmonary
Prior art date: 1995-11-20

Application number

AT96936751T

Other languages

English (en)

Inventor

James V Weber

Charles F Kasulanis

Keith Sampino

Original Assignee

Ortho Mcneil Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-11-20

Filing date

1996-10-22

Publication date

2002-05-15

1996-10-22 Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc

2002-05-15 Application granted granted Critical

2002-05-15 Publication of ATE216403T1 publication Critical patent/ATE216403T1/de

Links

108090000765 processed proteins & peptides Proteins 0.000 title 1
230000002685 pulmonary effect Effects 0.000 title 1
102000004169 proteins and genes Human genes 0.000 abstract 3
108090000623 proteins and genes Proteins 0.000 abstract 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
150000001298 alcohols Chemical class 0.000 abstract 1
238000002347 injection Methods 0.000 abstract 1
239000007924 injection Substances 0.000 abstract 1
239000002502 liposome Substances 0.000 abstract 1
239000003580 lung surfactant Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
230000003381 solubilizing effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0082—Lung surfactant, artificial mucus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pulmonology (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Nanotechnology (AREA)
Gastroenterology & Hepatology (AREA)
Dispersion Chemistry (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Crystallography & Structural Chemistry (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Medical Informatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT96936751T 1995-11-20 1996-10-22 Verfahren zur solubisierung des pulmonnären oberflächeraktiven peptides ATE216403T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US734795P	1995-11-20	1995-11-20
PCT/US1996/016804 WO1997019108A1 (en)	1995-11-20	1996-10-22	Pulmonary surfactant peptide solubilization process

Publications (1)

Publication Number	Publication Date
ATE216403T1 true ATE216403T1 (de)	2002-05-15

Family

ID=21725655

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96936751T ATE216403T1 (de)	1995-11-20	1996-10-22	Verfahren zur solubisierung des pulmonnären oberflächeraktiven peptides

Country Status (16)

Country	Link
US (1)	US5741891A (de)
EP (1)	EP0886652B1 (de)
JP (1)	JP3856343B2 (de)
KR (1)	KR100475294B1 (de)
AT (1)	ATE216403T1 (de)
AU (1)	AU721289B2 (de)
CA (1)	CA2236164C (de)
DE (1)	DE69620801T2 (de)
DK (1)	DK0886652T3 (de)
ES (1)	ES2176503T3 (de)
MX (1)	MX9803978A (de)
NO (1)	NO320442B1 (de)
PT (1)	PT886652E (de)
TW (1)	TW553748B (de)
WO (1)	WO1997019108A1 (de)
ZA (1)	ZA969692B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2066897A (en) *	1996-03-27	1997-10-17	Ortho Pharmaceutical Corporation	Manufacture of liposomes and lipid-protein complexes by ethanolic injection and thin film evaporation
SI1192184T1 (sl)	1999-06-17	2007-06-30	Nycomed Gmbh	Estri surfakantnega proteina C
WO2007002465A2 (en) *	2005-06-23	2007-01-04	Rapid Pharmaceuticals, Llc	Stabilizing alkylglycoside compositions and methods thereof
US20140141066A1 (en) *	2012-11-20	2014-05-22	Lipo Naturals Llc	Encapsulated Ascorbic Acid Composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5164369A (en) *	1988-01-06	1992-11-17	The Scripps Research Institute	Pulmonary surfactant protein and related polypeptide
US5260273A (en) *	1988-01-06	1993-11-09	The Scripps Research Institute	Pulmonary surfactant protein and related polypeptide
US4861756A (en) *	1988-03-08	1989-08-29	Merrell Dow Pharmaceuticals Inc.	Synthetic pulmonary surfactant
US5272252A (en) *	1991-11-04	1993-12-21	Merrell Dow Pharmaceuticals Inc.	Synthetic lung surfactant having antioxidant properties

1996
- 1996-10-22 JP JP51612397A patent/JP3856343B2/ja not_active Expired - Lifetime
- 1996-10-22 AT AT96936751T patent/ATE216403T1/de active
- 1996-10-22 KR KR10-1998-0703688A patent/KR100475294B1/ko not_active Expired - Lifetime
- 1996-10-22 US US08/735,171 patent/US5741891A/en not_active Expired - Lifetime
- 1996-10-22 CA CA002236164A patent/CA2236164C/en not_active Expired - Lifetime
- 1996-10-22 WO PCT/US1996/016804 patent/WO1997019108A1/en not_active Ceased
- 1996-10-22 AU AU74595/96A patent/AU721289B2/en not_active Expired
- 1996-10-22 DE DE69620801T patent/DE69620801T2/de not_active Expired - Lifetime
- 1996-10-22 DK DK96936751T patent/DK0886652T3/da active
- 1996-10-22 PT PT96936751T patent/PT886652E/pt unknown
- 1996-10-22 ES ES96936751T patent/ES2176503T3/es not_active Expired - Lifetime
- 1996-10-22 EP EP96936751A patent/EP0886652B1/de not_active Expired - Lifetime
- 1996-11-19 ZA ZA9609692A patent/ZA969692B/xx unknown
1997
- 1997-01-23 TW TW086100701A patent/TW553748B/zh not_active IP Right Cessation
1998
- 1998-05-19 NO NO19982279A patent/NO320442B1/no not_active IP Right Cessation
- 1998-05-19 MX MX9803978A patent/MX9803978A/es unknown

Also Published As

Publication number	Publication date
ZA969692B (en)	1998-05-19
JP2001527511A (ja)	2001-12-25
ES2176503T3 (es)	2002-12-01
AU7459596A (en)	1997-06-11
DK0886652T3 (da)	2002-08-12
DE69620801D1 (de)	2002-05-23
KR100475294B1 (ko)	2005-07-28
JP3856343B2 (ja)	2006-12-13
EP0886652B1 (de)	2002-04-17
KR19990067660A (ko)	1999-08-25
NO982279D0 (no)	1998-05-19
WO1997019108A1 (en)	1997-05-29
AU721289B2 (en)	2000-06-29
MX9803978A (es)	1998-09-30
NO982279L (no)	1998-05-19
CA2236164A1 (en)	1997-05-29
EP0886652A1 (de)	1998-12-30
DE69620801T2 (de)	2002-10-10
PT886652E (pt)	2002-09-30
CA2236164C (en)	2005-08-16
HK1015381A1 (en)	1999-10-15
TW553748B (en)	2003-09-21
NO320442B1 (no)	2005-12-05
US5741891A (en)	1998-04-21

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Legal Events

Date	Code	Title	Description
2002-08-15	UEP	Publication of translation of european patent specification