ATE216577T1 - Schnellösliche tablette und ihre herstellung - Google Patents

Schnellösliche tablette und ihre herstellung

Info

Publication number
ATE216577T1
ATE216577T1 AT93101170T AT93101170T ATE216577T1 AT E216577 T1 ATE216577 T1 AT E216577T1 AT 93101170 T AT93101170 T AT 93101170T AT 93101170 T AT93101170 T AT 93101170T AT E216577 T1 ATE216577 T1 AT E216577T1
Authority
AT
Austria
Prior art keywords
carbohydrate
fast dissolving
tablet
dissolving tablet
quick
Prior art date
Application number
AT93101170T
Other languages
English (en)
Inventor
Tadashi Makino
Masayuki Yamada
Jun-Ichi Kikuta
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11835174&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE216577(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE216577T1 publication Critical patent/ATE216577T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT93101170T 1992-01-29 1993-01-27 Schnellösliche tablette und ihre herstellung ATE216577T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1351192 1992-01-29

Publications (1)

Publication Number Publication Date
ATE216577T1 true ATE216577T1 (de) 2002-05-15

Family

ID=11835174

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93101170T ATE216577T1 (de) 1992-01-29 1993-01-27 Schnellösliche tablette und ihre herstellung

Country Status (8)

Country Link
US (2) US5501861A (de)
EP (1) EP0553777B1 (de)
JP (2) JP3069458B2 (de)
KR (1) KR100258223B1 (de)
AT (1) ATE216577T1 (de)
CA (1) CA2088334C (de)
DE (1) DE69331839T2 (de)
TW (1) TW249756B (de)

Families Citing this family (215)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2650493B2 (ja) * 1992-02-18 1997-09-03 日本新薬株式会社 速溶錠
DE69331378D1 (de) * 1992-02-18 2002-01-31 Nippon Shinyaku Co Ltd Verfahren zur Herstellung von schnelllöslicher Tabletten und schnelllöslichen Tablette beinhaltend Xylitol
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
MX9603035A (es) * 1994-01-31 1997-05-31 Yamanouchi Pharma Co Ltd Moldeos comprimidos que se disuelven intrabucalmente y proceso para su produccion.
US5576014A (en) * 1994-01-31 1996-11-19 Yamanouchi Pharmaceutical Co., Ltd Intrabuccally dissolving compressed moldings and production process thereof
DE4403943A1 (de) * 1994-02-08 1995-08-10 Hexal Pharma Gmbh Orale Azrneimittelzubereitung mit Diclofenac-Natrium
US5567439A (en) * 1994-06-14 1996-10-22 Fuisz Technologies Ltd. Delivery of controlled-release systems(s)
US5837287A (en) * 1994-10-28 1998-11-17 R P Scherer Corporation Process for preparing solid pharmaceutical dosage forms
US5994348A (en) 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
GB9517062D0 (en) * 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
US5762961A (en) * 1996-02-09 1998-06-09 Quadrant Holdings Cambridge Ltd. Rapidly soluble oral solid dosage forms, methods of making same, and compositions thereof
NZ512609A (en) * 1996-02-29 2003-03-28 Fujisawa Pharmaceutical Co Synthetic sweeteners, their production and uses thereof
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
ATE297191T1 (de) * 1996-06-14 2005-06-15 Kyowa Hakko Kogyo Kk Im munde schnellzerfallende tablette
GB9613470D0 (en) * 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
DE69738829D1 (de) * 1996-07-12 2008-08-21 Daiichi Seiyaku Co Schnell zerfallende, druckgeformte Materialien sowie Prozess zu deren Herstellung
ZA976189B (en) * 1996-07-12 1999-01-11 Novartis Consumer Health Sa Oral pharmaceutical combinations
US5846568A (en) * 1996-09-19 1998-12-08 Xyrofin Oy Directly compressible lactitol and method
US5958453A (en) 1996-10-31 1999-09-28 Takeda Chemical Industries, Ltd. Solid pharmaceutical preparation with improved buccal disintegrability and/or dissolubility
EP0955058B1 (de) * 1997-01-09 2004-05-26 Morinaga Milk Industry Co., Ltd. Lactoferrin-tabletten
EP0974366B1 (de) 1997-03-28 2006-10-18 Eisai Co., Ltd. Orale pharmazeutische zusammensetzungen mit reduzierter bitterkeit durch geschmacksmaskiermittel
US6024981A (en) * 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
US5939091A (en) * 1997-05-20 1999-08-17 Warner Lambert Company Method for making fast-melt tablets
JP4939680B2 (ja) * 1997-05-27 2012-05-30 武田薬品工業株式会社 固形製剤
TW580397B (en) 1997-05-27 2004-03-21 Takeda Chemical Industries Ltd Solid preparation
JP4947833B2 (ja) * 1997-07-25 2012-06-06 アルペックス・ファルマ・ソシエテ・アノニム 速崩壊性口内溶解錠の製造に適した顆粒の製造方法
TW527195B (en) 1997-10-09 2003-04-11 Ssp Co Ltd Fast-soluble solid pharmaceutical combinations
JPH11137208A (ja) * 1997-11-14 1999-05-25 Nikken Chem Co Ltd 口腔内速溶性固形物及びその製造方法
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
US6413541B1 (en) 1999-01-13 2002-07-02 Dainippon Pharmaceutical Co., Ltd. Disintegrating tablet in oral cavity and production thereof
US6432442B1 (en) * 1998-02-23 2002-08-13 Mcneil-Ppc, Inc. Chewable product
ES2178876T5 (es) * 1998-03-06 2012-10-01 Aptalis Pharma S.R.L. Pastilla de desintegración rápida
US6465009B1 (en) 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
US6974590B2 (en) * 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
US20030118645A1 (en) * 1998-04-29 2003-06-26 Pather S. Indiran Pharmaceutical compositions for rectal and vaginal administration
US20030091629A1 (en) * 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
AU3731699A (en) 1998-05-18 1999-12-06 Takeda Chemical Industries Ltd. Orally disintegrable tablets
JP4748627B2 (ja) 1998-07-15 2011-08-17 旭化成ケミカルズ株式会社 賦形剤
AU4802099A (en) * 1998-07-28 2000-02-21 Takeda Chemical Industries Ltd. Rapidly disintegrable solid preparation
EP1025858A4 (de) * 1998-08-28 2009-03-11 Eisai R&D Man Co Ltd Arzneimittel mit verminderter bitterkeit usw.
US8231899B2 (en) 1998-09-10 2012-07-31 Nycomed Danmark Aps Quick release pharmaceutical compositions of drug substances
JP5026635B2 (ja) * 1998-09-10 2012-09-12 ニュコメデ ダンマルク アンパーツセルスカブ 医薬物質の迅速放出医薬組成物
CA2346350C (en) 1998-10-05 2008-01-08 Eisai Co., Ltd. Intraoral quickly disintegrating tablets
JP2000178204A (ja) * 1998-10-05 2000-06-27 Eisai Co Ltd ホスフォジエステラ―ゼ阻害剤を含有する口腔内速崩壊性錠剤
US20010055613A1 (en) * 1998-10-21 2001-12-27 Beth A. Burnside Oral pulsed dose drug delivery system
US6296868B1 (en) * 1998-11-19 2001-10-02 Advanced Technology Pharmaceuticals Corporation Chewable tablets containing mannitol and aspartame
US7163705B2 (en) * 1998-12-15 2007-01-16 Wm. Wrigley Jr. Company Coated chewing gum product and method of making
US6552024B1 (en) 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
ATE283708T1 (de) * 1999-02-15 2004-12-15 Sumitomo Pharma Im mundraum schnellzerfallende tabletten
ATE297192T1 (de) * 1999-02-17 2005-06-15 Kyowa Hakko Kogyo Kk Tabletten und verfahren zur tablettenherstellung
GB9910505D0 (en) 1999-05-06 1999-07-07 Electrosols Ltd A method and apparatus for manufacturing consumable tablets
DE19931708A1 (de) * 1999-07-08 2001-01-18 Bayer Ag Verfahren zur Herstellung schnell zerfallender, fester pharmazeutischer Zubereitungen
US6384020B1 (en) * 1999-07-14 2002-05-07 Shire Laboratories, Inc. Rapid immediate release oral dosage form
US6284270B1 (en) 1999-08-04 2001-09-04 Drugtech Corporation Means for creating a mass having structural integrity
JP4719899B2 (ja) * 2000-01-07 2011-07-06 大正製薬株式会社 口腔内速崩壊性錠剤
EP1260215B1 (de) 2000-03-01 2009-07-29 Eisai R&D Management Co., Ltd. Schnellzerfallende polyvinylhaltige tablette
US20020015730A1 (en) * 2000-03-09 2002-02-07 Torsten Hoffmann Pharmaceutical formulations and method for making
EP1133984B1 (de) 2000-03-17 2005-05-11 Shin-Etsu Chemical Co., Ltd. Feste Zubereitung enthaltend niedersubstituierte Hydroxypropylcellulose und Herstellungsverfahren
AU4278301A (en) * 2000-03-27 2001-10-08 Kyowa Hakko Kogyo Co. Ltd. Easy-to-take granule
YU96602A (sh) 2000-06-27 2005-03-15 F.Hoffmann-La Roche Ag. Postupak za spravljanje smeše
US6656492B2 (en) * 2000-06-30 2003-12-02 Yamanouchi Pharmaceutical Co., Ltd. Quick disintegrating tablet in buccal cavity and manufacturing method thereof
AU2001267865A1 (en) 2000-06-30 2002-01-14 Yamanouchi Pharmaceutical Co..Ltd. Tablet rapidly disintegrating in mouth and process for producing the same
AU2001285011A1 (en) * 2000-08-18 2002-03-04 Pharmacia Corporation Rapidly disintegrating oral formulation of a cyclooxygenase-2 inhibitor
JP4886107B2 (ja) * 2000-10-13 2012-02-29 サンスター株式会社 歯周病予防用口腔内溶解錠
KR20030042006A (ko) * 2000-10-16 2003-05-27 다이이찌 세이야꾸 가부시기가이샤 구강내 속붕괴성 의약 조성물 및 그의 제조방법
US6733781B2 (en) * 2000-12-06 2004-05-11 Wyeth Fast dissolving tablet
US7799342B2 (en) 2000-12-06 2010-09-21 Wyeth Llc Fast dissolving tablet
US6544552B2 (en) 2001-01-11 2003-04-08 Particle And Coating Technologies, Inc. Method of producing porous tablets with improved dissolution properties
US20030022912A1 (en) * 2001-02-08 2003-01-30 Martino Alice C. Rapid-onset medicament for treatment of sexual dysfunction
US7927623B2 (en) * 2001-02-15 2011-04-19 Mitsubishi Tanabe Pharma Corporation Tablets quickly disintegrated in oral cavity
US20040071772A1 (en) * 2001-03-06 2004-04-15 Shoichi Narita Preparations quickly disintegrating in oral cavity
US6706284B2 (en) 2001-03-15 2004-03-16 Yamanouchi Pharmaceutical Co., Ltd. Bitterness-reduced oral pharmaceutical composition
US20040131673A1 (en) * 2001-03-22 2004-07-08 Coffee Ronald Alan Manufacturing dissolvable dosage forms
KR100457458B1 (ko) * 2001-04-02 2004-11-17 삼아약품 주식회사 속용정 및 그의 제조방법
EP1405635A1 (de) * 2001-06-07 2004-04-07 Tanabe Seiyaku Co., Ltd. Funktionale körnchen enthaltende präparate, die sich in der mundhöhle schnell auflösen
JP2005519865A (ja) * 2001-09-25 2005-07-07 ランバクシー ラボラトリーズ リミテッド 急速溶解性投薬形態物の製造方法
US7037524B2 (en) * 2001-10-03 2006-05-02 Herbalscience, Llc Oral delivery of a botanical
US20050053678A1 (en) * 2001-10-03 2005-03-10 Gow Robert T. Methods and compositions for betel nut chewing gum
US7291352B2 (en) 2001-10-03 2007-11-06 Herbalscience Llc Methods and compositions for oral delivery of Areca and mate' or theobromine
US20050069596A1 (en) * 2001-10-03 2005-03-31 Gow Robert T. Compositions and methods comprising kava and anti-anxiety compounds
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US20040047904A1 (en) * 2001-11-13 2004-03-11 Motohiro Ohta Amino acid-containing tablets quickly disintegrating in the oral cavity and process for producing the same
CA2467490C (en) * 2001-11-30 2007-01-09 Pfizer Products Inc. Pharmaceutical compositions of 5,8,14-triazatetracyclo[10.3.1.0(2,11).0(4,9)]-hexadeca-2(11)3,5,7,9-pentaene
US7118765B2 (en) 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
JP2003238393A (ja) * 2002-02-15 2003-08-27 Otsuka Pharmaceut Co Ltd 施錠性が改善された錠剤及びその製造方法
CN1638803A (zh) * 2002-03-06 2005-07-13 协和发酵工业株式会社 口腔内速崩解性片剂
AU2003222027A1 (en) * 2002-03-20 2003-10-08 Elan Pharma International Limited Fast dissolving dosage forms having reduced friability
US20030215498A1 (en) * 2002-05-17 2003-11-20 Harland Ronald S. Rapidly disintegrating comressed tablets comprising biologically active compounds
JP4605977B2 (ja) * 2002-06-14 2011-01-05 日本ベーリンガーインゲルハイム株式会社 ブロチゾラムを含有する錠剤
US20040001885A1 (en) * 2002-06-27 2004-01-01 Unchalee Kositprapa Rapidly disintegrating antihistamine formulation
US20030017208A1 (en) * 2002-07-19 2003-01-23 Francis Ignatious Electrospun pharmaceutical compositions
GB0217056D0 (en) * 2002-07-23 2002-08-28 Ass Octel Use
JPWO2004016262A1 (ja) * 2002-08-12 2005-12-02 協和醗酵工業株式会社 アミノ酸含有チュアブル錠
US20050037025A1 (en) * 2002-10-03 2005-02-17 Gow Robert T. Methods and compositions comprising kava and mate' or theobromine
US20050043296A1 (en) * 2002-10-04 2005-02-24 Michael Hawley Compositions and methods for treating sexual dysfunction
UA80991C2 (en) * 2002-10-07 2007-11-26 Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes
FR2845914B1 (fr) * 2002-10-18 2005-11-04 Schwarz Pharma Lab Compose antiemetique a desagregation rapide
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US20040161459A1 (en) * 2002-12-31 2004-08-19 Ngoc Do Fast-dissolve tablet technology
WO2004098571A1 (en) * 2003-04-30 2004-11-18 Zicam, Llc Cold remedy composition comprising zinc salts
US7204986B2 (en) 2003-06-11 2007-04-17 Ultra Biotech Limited Method to prepare compositions comprising yeast treated with electromagnetic energy
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
US7282217B1 (en) 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
CA2785138A1 (en) * 2003-10-07 2005-04-21 Andrx Pharmaceuticals Llc Rapidly disintegrating formulation
US8349361B2 (en) 2003-10-15 2013-01-08 Fuji Chemical Industry Co., Ltd. Composition for rapid disintegrating tablet in oral cavity
JP3841804B2 (ja) 2003-10-15 2006-11-08 富士化学工業株式会社 口腔内速崩壊性錠剤用の組成物
EP1674083B1 (de) 2003-10-15 2018-08-01 Fuji Chemical Industry Co., Ltd. Tablette mit schneller auflösung in der mundhöhle
EP1535700A1 (de) * 2003-11-25 2005-06-01 Sika Tivoli GmbH Schleifmittelverbundkörper
WO2005065318A2 (en) * 2003-12-31 2005-07-21 Cima Labs Inc. Effervescent oral opiate dosage form
WO2005065317A2 (en) * 2003-12-31 2005-07-21 Cima Labs Inc. Effervescent oral fentanyl dosage form
WO2005065319A2 (en) * 2003-12-31 2005-07-21 Cima Labs Inc. Generally linear effervescent oral fentanyl dosage form and methods of administering
US7670624B2 (en) 2004-01-29 2010-03-02 Astella Pharma Inc. Gastrointestinal-specific multiple drug release system
RU2252759C1 (ru) * 2004-02-17 2005-05-27 ООО "Инполимед АО" Средство для купирования и лечения ишемической болезни сердца и способ его производства
US20090246288A1 (en) * 2004-02-25 2009-10-01 Pharmaceutical Industry Technology And Development Center Taste-masking oral dosage form and method of preparing the same
TWI335227B (en) * 2004-02-25 2011-01-01 Medical & Pharm Ind Tech & Dev Pharmaceutical composition of taste masking and rapidly dissolving drug and method of preparing the same
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
EP1750862B1 (de) * 2004-06-04 2011-01-05 Teva Pharmaceutical Industries Ltd. Irbesartan enthaltende pharmazeutische zusammensetzung
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
ES2409347T3 (es) * 2004-10-21 2013-06-26 Aptalis Pharmatech, Inc. Composiciones farmacéuticas de sabor enmascarado con agentes porogénicos gastrosolubles
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
ITMI20042356A1 (it) * 2004-12-10 2005-03-10 Acraf Composizione farmaceutica orodisperdibile e procedimento per prepararla
NL1027807C1 (nl) * 2004-12-17 2006-06-20 4Sight Innovation Bv Inrichting voor het verrijken van een drank met additieven, en verpakking voor een dergelijke inrichting.
WO2006115770A2 (en) * 2005-04-22 2006-11-02 Teva Pharmaceuticals Usa, Inc. Orally disintegrating pharmaceutical tablet formulations of olanzapine
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
US20070020186A1 (en) 2005-07-22 2007-01-25 Alpex Pharma S.A. Solid dosage formulations of narcotic drugs having improved buccal adsorption
WO2007011018A1 (ja) * 2005-07-22 2007-01-25 Mitsubishi Tanabe Pharma Corporation 口腔内速崩壊性錠
WO2007019417A1 (en) 2005-08-04 2007-02-15 Sirtris Pharmaceuticals, Inc. Oxazolopyridine derivatives as sirtuin modulators
US20110142957A1 (en) * 2005-08-15 2011-06-16 Van Kempen Theo Method of treating parturient placental mammals in order to reduce maternal and/or uterine exhaustion
EP1942877A4 (de) * 2005-11-02 2011-09-14 Teikoku Pharma Usa Inc Organoleptisch annehmbare orale dosierformen von ibuprofen, herstellungsverfahren und anwendung
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
PE20070698A1 (es) 2005-11-14 2007-08-17 Teijin Pharma Ltd Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
US8956677B2 (en) * 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with glucosamine and compositions sweetened therewith
US8377491B2 (en) * 2005-11-23 2013-02-19 The Coca-Cola Company High-potency sweetener composition with vitamin and compositions sweetened therewith
US8524303B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with phytosterol and compositions sweetened therewith
US8524304B2 (en) * 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith
US20070116829A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Pharmaceutical Composition with High-Potency Sweetener
US20070116831A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Dental Composition with High-Potency Sweetener
US9144251B2 (en) * 2005-11-23 2015-09-29 The Coca-Cola Company High-potency sweetener composition with mineral and compositions sweetened therewith
US20070116836A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Osteoporosis and Compositions Sweetened Therewith
CA2629556A1 (en) * 2005-11-23 2007-07-19 The Coca Cola Company Synthetic sweetener compositions with improved temporal profile and/or flavor profile, methods for their formulation, and uses
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US20070116825A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Confection with High-Potency Sweetener
US20070116833A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition with Calcium and Compositions Sweetened Therewith
US8435587B2 (en) * 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with long-chain primary aliphatic saturated alcohol and compositions sweetened therewith
US8993027B2 (en) * 2005-11-23 2015-03-31 The Coca-Cola Company Natural high-potency tabletop sweetener compositions with improved temporal and/or flavor profile, methods for their formulation, and uses
US20070134391A1 (en) * 2005-11-23 2007-06-14 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Autoimmune Disorders and Compositions Sweetened Therewith
US20070116822A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-potency sweetener composition with saponin and compositions sweetened therewith
US8956678B2 (en) * 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with preservative and compositions sweetened therewith
US20070116800A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Chewing Gum with High-Potency Sweetener
US20070116839A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition With C-Reactive Protein Reducing Substance and Compositions Sweetened Therewith
US8512789B2 (en) * 2005-11-23 2013-08-20 The Coca-Cola Company High-potency sweetener composition with dietary fiber and compositions sweetened therewith
MY149082A (en) 2005-12-28 2013-07-15 Meiji Co Ltd Solid milk and method of making the same
JP5100634B2 (ja) * 2006-03-24 2012-12-19 興和株式会社 口腔内速崩壊性錠剤
US8846100B2 (en) * 2006-05-12 2014-09-30 Shire Llc Controlled dose drug delivery system
EP2043613A1 (de) * 2006-07-14 2009-04-08 Fmc Corporation Feste form
EP1891946A1 (de) * 2006-08-14 2008-02-27 Santhera Pharmaceuticals (Schweiz) AG Transmukosale Verabreichung von 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinon
EP2062599A4 (de) 2006-09-14 2013-03-27 Astellas Pharma Inc Oral zerfallende tablette und verfahren zu ihrer herstellung
ES2370062T3 (es) * 2006-09-15 2011-12-12 Echo Pharmaceuticals B.V. Granulado que contiene una sustancia farmacéuticamente activa y un emulsionante y método para su producción.
US20080107787A1 (en) * 2006-11-02 2008-05-08 The Coca-Cola Company Anti-Diabetic Composition with High-Potency Sweetener
US8017168B2 (en) * 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
US9101161B2 (en) * 2006-11-02 2015-08-11 The Coca-Cola Company High-potency sweetener composition with phytoestrogen and compositions sweetened therewith
JPWO2008084676A1 (ja) * 2006-12-26 2010-04-30 株式会社 メドレックス 多孔性乾燥マトリックスの医薬組成物
JP5366558B2 (ja) 2006-12-28 2013-12-11 武田薬品工業株式会社 口腔内崩壊性固形製剤
ES2302650B1 (es) 2007-01-11 2009-02-16 Tedec-Meiji Farma, S.A. Composicion de rapida desintegracion en la cavidad bucal.
US20080187628A1 (en) * 2007-02-02 2008-08-07 Champion Melinda L Water-Soluble, Quick-Dissolve Flavor Tablets
US20080260823A1 (en) * 2007-04-20 2008-10-23 Sciele Pharma, Inc. Orally disintegrating tablet comprising glycopyrrolate for treating sialorrhea
US20080311162A1 (en) * 2007-05-16 2008-12-18 Olivia Darmuzey Solid form
JP4980144B2 (ja) * 2007-06-05 2012-07-18 日機装株式会社 固型化透析用剤の製造方法
JP2009035505A (ja) * 2007-08-01 2009-02-19 Takada Seiyaku Kk レボフロキサシン錠剤
US20090060983A1 (en) * 2007-08-30 2009-03-05 Bunick Frank J Method And Composition For Making An Orally Disintegrating Dosage Form
CA2704209C (en) * 2007-10-31 2017-02-28 Mcneil-Ppc, Inc. Orally disintegrative dosage form
JP4832407B2 (ja) * 2007-11-19 2011-12-07 花王株式会社 コラーゲン含有組成物
EP2227226B1 (de) * 2007-12-21 2016-10-26 Johnson & Johnson Consumer Inc. Herstellung einer tablette
BRPI0908539B8 (pt) * 2008-02-28 2021-05-25 Scherer Technologies Llc R P processo para a preparação de uma forma sólida rápida de dosagem da dispersão, oral de alprazolam
EP2100595A1 (de) * 2008-03-10 2009-09-16 The Procter and Gamble Company Komprimierte Tabletten
US20100075930A1 (en) * 2008-09-03 2010-03-25 Yoel Ovil Salicylic salt compositions and related method of treatment of cardiac conditions
CA2750216A1 (en) * 2008-12-15 2010-07-08 Fleming And Company, Pharmaceuticals Rapidly dissolving vitamin formulation and methods of using the same
EP3031451B1 (de) 2009-01-26 2018-03-07 Shin-Etsu Chemical Co., Ltd Nassgranulationstablettierungsverfahren unter verwendung wässriger dispersion von niedrig substituierter hydroxypropylcellulose
MX2011009053A (es) * 2009-03-09 2012-04-02 Spi Pharma Inc Excipientes de compresion directa con alta capacidad de compactacion y durables y sistemas de excipiente.
EP2440210A4 (de) * 2009-06-12 2014-01-29 Meritage Pharma Inc Verfahren zur behandlung von magen-darm-erkrankungen
JP2011037767A (ja) * 2009-08-11 2011-02-24 Dainippon Sumitomo Pharma Co Ltd 薬物および噴霧乾燥粒子を含有する口腔内速崩壊錠
US8858210B2 (en) 2009-09-24 2014-10-14 Mcneil-Ppc, Inc. Manufacture of variable density dosage forms utilizing radiofrequency energy
US8313768B2 (en) 2009-09-24 2012-11-20 Mcneil-Ppc, Inc. Manufacture of tablet having immediate release region and sustained release region
US20110070286A1 (en) * 2009-09-24 2011-03-24 Andreas Hugerth Process for the manufacture of nicotine-comprising chewing gum and nicotine-comprising chewing gum manufactured according to said process
US20110070301A1 (en) * 2009-09-24 2011-03-24 Luber Joseph R Orally transformable tablets
RU2563623C2 (ru) 2009-12-02 2015-09-20 Апталис Фарма Лимитед Микрокапсулы фексофенадина и содержащие их композиции
US20110212171A1 (en) * 2010-01-08 2011-09-01 Eurand, Inc. Taste masked topiramate composition and an orally disintegrating tablet comprising the same
JP5513936B2 (ja) * 2010-03-10 2014-06-04 全星薬品工業株式会社 口腔内崩壊製剤
JP2010174028A (ja) * 2010-03-18 2010-08-12 Rohto Pharmaceut Co Ltd 苦味を有する薬物を含有する口中溶解型又は咀嚼型固形内服医薬組成物
KR101232088B1 (ko) * 2010-05-11 2013-02-08 박대철 용해성이 향상된 태블릿 제조방법
IN2013DN02552A (de) 2010-09-01 2015-08-07 Arena Pharm Inc
WO2012075455A2 (en) 2010-12-02 2012-06-07 Aptalis Pharmatech, Inc. Rapidly dispersing granules, orally disintegrating tablets and methods
SG10201602311XA (en) 2010-12-27 2016-04-28 Takeda Pharmaceutical Orally disintegrating tablet
MX2014007933A (es) 2011-12-26 2014-07-30 Novartis Ag Comprimidos y agentes recubiertos en seco.
KR20130076015A (ko) 2011-12-28 2013-07-08 주식회사 삼양바이오팜 높은 경도를 갖는 속붕정 및 이의 제조 방법
US9445971B2 (en) 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
US9233491B2 (en) 2012-05-01 2016-01-12 Johnson & Johnson Consumer Inc. Machine for production of solid dosage forms
JP2013028647A (ja) * 2012-11-06 2013-02-07 Rohto Pharmaceutical Co Ltd 苦味を有する薬物を含有する口中溶解型又は咀嚼型固形内服医薬組成物
FR2999432B1 (fr) 2012-12-17 2014-12-12 Ethypharm Sa Comprimes orodispersibles obtenus par compression moulage
US12274276B2 (en) * 2013-10-03 2025-04-15 Altria Client Services Llc Dissolvable-chewable tablet
EP3068396B1 (de) 2013-11-11 2019-05-08 Impax Laboratories, Inc. Schnell zerfallende formulierungen und verfahren zur verwendung
US9789066B2 (en) 2014-01-10 2017-10-17 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
US9925138B2 (en) 2015-01-20 2018-03-27 Handa Pharmaceuticals, Llc Stable solid fingolimod dosage forms
WO2016155786A1 (en) 2015-03-31 2016-10-06 Laboratorios Bagó S.A. Enteric-coated pellets containing a proton pump inhibitor
JP6552088B2 (ja) * 2015-04-21 2019-07-31 ライオン株式会社 造粒顆粒およびその製造方法と、錠剤およびその製造方法
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
CN113876725A (zh) * 2020-10-12 2022-01-04 北京中科利华医药研究院有限公司 一种维生素b6片剂及其制备方法
WO2022103634A1 (en) 2020-11-16 2022-05-19 Orcosa Inc. Improved use of cannabinoids in the treatment of epilepsy
US11672761B2 (en) 2020-11-16 2023-06-13 Orcosa Inc. Rapidly infusing platform and compositions for therapeutic treatment in humans
US20240316049A1 (en) * 2021-07-07 2024-09-26 Sun Pharma Advanced Research Company Limited Stabilization of phenobarbital sodium for injection
JP2023125300A (ja) * 2022-02-28 2023-09-07 アルフレッサファーマ株式会社 湿製錠剤及び湿製錠剤の製造方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2926121A (en) * 1957-03-20 1960-02-23 American Home Prod Therapeutic candy-like product and its preparation
GB1134097A (en) * 1965-11-25 1968-11-20 Internat Chemical Company Ltd Improvements in antacid tablets
DE2556561C2 (de) * 1975-12-16 1983-04-14 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Herstellung von porösen Tabletten
JPS5824410A (ja) * 1981-08-06 1983-02-14 Toppan Printing Co Ltd チユ−ブの製造方法
GB2111423B (en) * 1981-12-02 1985-06-26 Wyeth John & Brother Ltd Making quick-dissolving pills
US4414198A (en) * 1982-04-23 1983-11-08 Joseph Michaelson Rapidly disintegrable tablet composition and method
ES8605956A1 (es) * 1984-06-28 1986-04-01 Searle & Co Procedimiento para preparar una composicion antiacido
US4684534A (en) * 1985-02-19 1987-08-04 Dynagram Corporation Of America Quick-liquifying, chewable tablet
DE68916983T2 (de) * 1988-02-25 1995-01-19 Yamanouchi Europ Bv Verfahren zur Herstellung eines pharmazeutischen Granulats.
US5082667A (en) * 1988-06-07 1992-01-21 Abbott Laboratories Solid pharmaceutical dosage in tablet triturate form and method of producing same
US5073374A (en) * 1988-11-30 1991-12-17 Schering Corporation Fast dissolving buccal tablet
US5112616A (en) * 1988-11-30 1992-05-12 Schering Corporation Fast dissolving buccal tablet
US4946684A (en) * 1989-06-20 1990-08-07 American Home Products Corporation Fast dissolving dosage forms
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution
NZ246091A (en) * 1991-12-24 1995-08-28 Yamanouchi Pharma Co Ltd Intrabuccally disintegrating preparation containing an active ingredient, agar, and lactose and/or mannitol
TW272942B (de) * 1993-02-10 1996-03-21 Takeda Pharm Industry Co Ltd

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EP0553777A2 (de) 1993-08-04
EP0553777A3 (en) 1994-12-14
DE69331839D1 (de) 2002-05-29
CA2088334C (en) 2004-06-15
CA2088334A1 (en) 1993-07-30
JPH05271054A (ja) 1993-10-19
TW249756B (de) 1995-06-21
JP4336021B2 (ja) 2009-09-30
US5501861A (en) 1996-03-26
US5720974A (en) 1998-02-24
KR100258223B1 (ko) 2000-08-01
JP3069458B2 (ja) 2000-07-24
DE69331839T2 (de) 2002-12-12
JP2000264836A (ja) 2000-09-26
EP0553777B1 (de) 2002-04-24

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