ATE216693T1 - Verfahren zur herstellung von ioversol - Google Patents

Verfahren zur herstellung von ioversol

Info

Publication number
ATE216693T1
ATE216693T1 AT97903077T AT97903077T ATE216693T1 AT E216693 T1 ATE216693 T1 AT E216693T1 AT 97903077 T AT97903077 T AT 97903077T AT 97903077 T AT97903077 T AT 97903077T AT E216693 T1 ATE216693 T1 AT E216693T1
Authority
AT
Austria
Prior art keywords
bis
reacting
produce
product
triiodoisopthalamide
Prior art date
Application number
AT97903077T
Other languages
English (en)
Inventor
Thomas Jeffrey Dunn
David H White
Mills Thomas Kneller
Michelle M Jones
Narcisco Ocampo Doran Iii
Allan R Bailey
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Application granted granted Critical
Publication of ATE216693T1 publication Critical patent/ATE216693T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
AT97903077T 1996-01-29 1997-01-27 Verfahren zur herstellung von ioversol ATE216693T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/593,775 US6596904B1 (en) 1996-01-29 1996-01-29 Process for producing ioversol
PCT/US1997/001078 WO1997027172A1 (en) 1996-01-29 1997-01-27 Process for producing ioversol

Publications (1)

Publication Number Publication Date
ATE216693T1 true ATE216693T1 (de) 2002-05-15

Family

ID=24376118

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97903077T ATE216693T1 (de) 1996-01-29 1997-01-27 Verfahren zur herstellung von ioversol

Country Status (7)

Country Link
US (1) US6596904B1 (de)
EP (1) EP0886634B1 (de)
AT (1) ATE216693T1 (de)
AU (1) AU1708197A (de)
DE (1) DE69712193T2 (de)
ES (1) ES2175340T3 (de)
WO (1) WO1997027172A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9624612D0 (en) 1996-11-26 1997-01-15 Nycomed Imaging As Process
GB9725010D0 (en) * 1997-11-26 1998-01-28 Nycomed Imaging As Process
SE520688C2 (sv) * 2000-04-11 2003-08-12 Bone Support Ab Ett injicerbart ersättningsmaterial för benmineral
SE517168C2 (sv) * 2000-07-17 2002-04-23 Bone Support Ab En komposition för ett injicerbart ersättningsmaterial för benmineral
SE522098C2 (sv) * 2001-12-20 2004-01-13 Bone Support Ab Ett nytt benmineralsubstitut
SE0300620D0 (sv) * 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
SE0302983D0 (sv) * 2003-11-11 2003-11-11 Bone Support Ab Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
SE527528C2 (sv) * 2004-06-22 2006-04-04 Bone Support Ab Anordning för framställning av härdbar massa samt användning av anordningen
WO2008104853A1 (en) * 2007-02-26 2008-09-04 Wockhardt Research Centre Processes for the preparation of pure ioversol
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
CA2901528C (en) 2013-02-20 2022-07-26 Bone Support Ab Heat-treated, sintered and micronized hydroxyapatite powder for use in a hardenable bone substitute composition
CN107698456A (zh) * 2017-05-22 2018-02-16 成都丽璟科技有限公司 一种碘佛醇及其合成方法
CN110028418A (zh) * 2019-03-26 2019-07-19 大道隆达（北京）医药科技发展有限公司 一种碘佛醇的制备方法
CN117756660B (zh) * 2024-01-19 2026-03-17 重庆圣华曦药业股份有限公司 一种碘佛醇杂质的去除方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4396598A (en) * 1982-01-11 1983-08-02 Mallinckrodt, Inc. Triiodoisophthalamide X-ray contrast agent
US4997983A (en) * 1990-01-31 1991-03-05 Mallinckrodt, Inc. Process for production of ioversol
US5177261A (en) * 1991-07-22 1993-01-05 Mallinckrodt Medical, Inc. Synthesis of ioversol using chloroacetyl chloride
US5648536A (en) * 1995-06-07 1997-07-15 Dunn; Thomas Jeffrey Process for producing ioversol

Also Published As

Publication number Publication date
ES2175340T3 (es) 2002-11-16
EP0886634B1 (de) 2002-04-24
DE69712193T2 (de) 2003-08-07
WO1997027172A1 (en) 1997-07-31
DE69712193D1 (de) 2002-05-29
US6596904B1 (en) 2003-07-22
AU1708197A (en) 1997-08-20
EP0886634A4 (de) 2000-08-02
EP0886634A1 (de) 1998-12-30

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