ATE216698T1 - Tetrazolderivate als ltd4 und h1 antagonisten - Google Patents

Tetrazolderivate als ltd4 und h1 antagonisten

Info

Publication number: ATE216698T1
Authority: AT; Austria
Prior art keywords: group; substituted; unsubstituted; hydrogen atom; lower alkyl
Prior art date: 1997-09-26

Application number

AT98118064T

Other languages

English (en)

Inventor

Hendrik Timmerman

Mingqiang Zang

Kazuhiro Onogi

Takeo Deushi

Masahiro Tamura

Tsutomu Tohma

Yasushi Wada

Jiro Matsumoto

Toru Kanke

Original Assignee

Kowa Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-26

Filing date

1998-09-23

Publication date

2002-05-15

1998-09-23 Application filed by Kowa Co filed Critical Kowa Co

2002-05-15 Application granted granted Critical

2002-05-15 Publication of ATE216698T1 publication Critical patent/ATE216698T1/de

Links

150000003536 tetrazoles Chemical class 0.000 title abstract 2
239000005557 antagonist Substances 0.000 title 1
YEESKJGWJFYOOK-IJHYULJSSA-N leukotriene D4 Chemical compound CCCCC\C=C/C\C=C/C=C/C=C/[C@H]([C@@H](O)CCCC(O)=O)SC[C@H](N)C(=O)NCC(O)=O YEESKJGWJFYOOK-IJHYULJSSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 2
239000003814 drug Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
239000004480 active ingredient Substances 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
230000001387 anti-histamine Effects 0.000 abstract 1
230000002590 anti-leukotriene effect Effects 0.000 abstract 1
208000006673 asthma Diseases 0.000 abstract 1
125000003785 benzimidazolyl group Chemical group N1=C(NC2=C1C=CC=C2)* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
125000005678 ethenylene group Chemical group [H]C([*:1])=C([H])[*:2] 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000005699 methyleneoxy group Chemical group [H]C([H])([*:1])O[*:2] 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
125000002294 quinazolinyl group Chemical group N1=C(N=CC2=CC=CC=C12)* 0.000 abstract 1
125000005493 quinolyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pulmonology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Die Bonding (AREA)
Adhesives Or Adhesive Processes (AREA)

AT98118064T 1997-09-26 1998-09-23 Tetrazolderivate als ltd4 und h1 antagonisten ATE216698T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP26235697		1997-09-26

Publications (1)

Publication Number	Publication Date
ATE216698T1 true ATE216698T1 (de)	2002-05-15

Family

ID=17374614

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98118064T ATE216698T1 (de)	1997-09-26	1998-09-23	Tetrazolderivate als ltd4 und h1 antagonisten

Country Status (6)

Country	Link
US (2)	US6121286A (de)
EP (1)	EP0905133B1 (de)
KR (1)	KR100547506B1 (de)
AT (1)	ATE216698T1 (de)
DE (1)	DE69805033T2 (de)
ES (1)	ES2176877T3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69827233T2 (de) *	1997-07-07	2005-03-24	Kowa Co., Ltd., Nagoya	Diaminderivate und diese enthaltende arzneimittel
NZ516111A (en) *	1999-05-24	2003-05-30	Mitsubishi Pharma Corp	Phenoxypropylamine compounds useful to treat depression
WO2003000685A1 (fr) *	2001-06-20	2003-01-03	Takeda Chemical Industries, Ltd.	Derives heterocycliques a 5 chainons
US7148248B2 (en)	2002-11-29	2006-12-12	Masako Nozaki	Method of treating or inhibiting the development of brain inflammation and sepsis
EP1424101A3 (de) *	2002-11-29	2004-08-18	NOZAKI, Masako	Verwendung eines Leukotrien- C4/ D4 -rezeptorantagonisten zur Herstellung eines Medikamentes zur Behandlung oder Vorbeugung von Gehirnentzündung und -sepsis
CN101022796B (zh)	2004-07-14	2013-02-27	炎症研究中心有限公司	抑制肿瘤转移的方法
AR057455A1 (es) *	2005-07-22	2007-12-05	Merck & Co Inc	Inhibidores de la transcriptasa reversa de vih y composicion farmaceutica
US8507385B2 (en) *	2008-05-05	2013-08-13	Shanghai Lexvu Opto Microelectronics Technology Co., Ltd.	Method for processing a thin film micro device on a substrate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8728051D0 (en) *	1987-12-01	1988-01-06	Leo Pharm Prod Ltd	Chemical compounds
US5486612A (en) *	1993-12-14	1996-01-23	Eli Lilly And Company	N-benzyl dihydroindole LTD4 antagonists
US5756518A (en) *	1996-04-02	1998-05-26	Kowa Co., Ltd.	Phenylene derivatives
DE69827233T2 (de) *	1997-07-07	2005-03-24	Kowa Co., Ltd., Nagoya	Diaminderivate und diese enthaltende arzneimittel

1998
- 1998-09-23 KR KR1019980039489A patent/KR100547506B1/ko not_active Expired - Fee Related
- 1998-09-23 US US09/158,774 patent/US6121286A/en not_active Expired - Fee Related
- 1998-09-23 ES ES98118064T patent/ES2176877T3/es not_active Expired - Lifetime
- 1998-09-23 DE DE69805033T patent/DE69805033T2/de not_active Expired - Lifetime
- 1998-09-23 AT AT98118064T patent/ATE216698T1/de not_active IP Right Cessation
- 1998-09-23 EP EP98118064A patent/EP0905133B1/de not_active Expired - Lifetime
1999
- 1999-07-19 US US09/357,156 patent/US6117886A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0905133A1 (de)	1999-03-31
EP0905133B1 (de)	2002-04-24
ES2176877T3 (es)	2002-12-01
DE69805033D1 (de)	2002-05-29
KR100547506B1 (ko)	2006-06-22
US6121286A (en)	2000-09-19
DE69805033T2 (de)	2002-11-14
US6117886A (en)	2000-09-12
KR19990030070A (ko)	1999-04-26

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Legal Events

Date	Code	Title	Description
2002-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties