ATE216881T1 - Zusammensetzung auf basis von enalapril und losartan - Google Patents

Zusammensetzung auf basis von enalapril und losartan

Info

Publication number: ATE216881T1
Authority: AT; Austria
Prior art keywords: losartan; enalapril; composition based; relates; present
Prior art date: 1996-06-24

Application number

AT97932188T

Other languages

English (en)

Inventor

Tzyy-Show H Chen

William Grossman

Bassel Iskandarani

Kenneth A Kramer

Charles S Sweet

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-24

Filing date

1997-06-20

Publication date

2002-05-15

1996-07-19 Priority claimed from GBGB9615182.4A external-priority patent/GB9615182D0/en

1997-06-20 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

2002-05-15 Application granted granted Critical

2002-05-15 Publication of ATE216881T1 publication Critical patent/ATE216881T1/de

Links

239000002083 C09CA01 - Losartan Substances 0.000 title abstract 3
108010061435 Enalapril Proteins 0.000 title abstract 3
GBXSMTUPTTWBMN-XIRDDKMYSA-N enalapril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(O)=O)CC1=CC=CC=C1 GBXSMTUPTTWBMN-XIRDDKMYSA-N 0.000 title abstract 3
229960000873 enalapril Drugs 0.000 title abstract 3
KJJZZJSZUJXYEA-UHFFFAOYSA-N losartan Chemical compound CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C=2[N]N=NN=2)C=C1 KJJZZJSZUJXYEA-UHFFFAOYSA-N 0.000 title abstract 3
229960004773 losartan Drugs 0.000 title abstract 3
206010019280 Heart failures Diseases 0.000 abstract 1
206010020772 Hypertension Diseases 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Vascular Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

AT97932188T 1996-06-24 1997-06-20 Zusammensetzung auf basis von enalapril und losartan ATE216881T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US2030196P	1996-06-24	1996-06-24
GBGB9615182.4A GB9615182D0 (en)	1996-07-19	1996-07-19	A composition of enalapril and losartan
PCT/US1997/010372 WO1997049392A1 (en)	1996-06-24	1997-06-20	A composition of enalapril and losartan

Publications (1)

Publication Number	Publication Date
ATE216881T1 true ATE216881T1 (de)	2002-05-15

Family

ID=26309722

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97932188T ATE216881T1 (de)	1996-06-24	1997-06-20	Zusammensetzung auf basis von enalapril und losartan

Country Status (8)

Country	Link
EP (1)	EP0910375B1 (de)
JP (1)	JP2000513356A (de)
AT (1)	ATE216881T1 (de)
AU (1)	AU724576B2 (de)
CA (1)	CA2257946A1 (de)
DE (1)	DE69712338T2 (de)
ES (1)	ES2175437T3 (de)
WO (1)	WO1997049392A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101011390A (zh)	1999-01-26	2007-08-08	诺瓦提斯公司	血管紧张素ⅱ受体拮抗剂在治疗急性心肌梗塞中的应用
SE9903028D0 (sv) *	1999-08-27	1999-08-27	Astra Ab	New use
DK1216038T3 (da)	1999-08-30	2005-12-27	Sanofi Aventis Deutschland	Anvendelse af inhibitorer af reninangiotensinsystemet ved forebyggelsen af cardiovaskulære hændelser
GB0020691D0 (en) *	2000-08-22	2000-10-11	Boehringer Ingelheim Pharma	Pharmaceutical combination
UY26893A1 (es) *	2000-08-22	2002-03-22	Boehringer Ingelheim Pharma	Combinación farmacéutica de antagonistas de la angiotensina ii e inhibidores de la enzima de conversión de la angiotensina i
EP1413315A4 (de) *	2001-08-03	2006-08-16	Takeda Pharmaceutical	Medikamente mit verzögerter freisetzung
JP2005508358A (ja) *	2001-10-25	2005-03-31	デポメド・インコーポレイテッド	胃滞留型ロサルタン投与量を用いる治療方法
EP1906936A2 (de) *	2005-05-18	2008-04-09	Combino Pharm, S.L.	Formulierungen mit losartan und/oder dessen salzen
EP1908469A1 (de)	2006-10-06	2008-04-09	Boehringer Ingelheim Vetmedica Gmbh	Angiotensin II Rezeptor Antagonisten zur Behandlung von systemischen Krankheiten bei Katzen
KR101247583B1 (ko) *	2006-12-08	2013-03-26	한미사이언스 주식회사	암로디핀 또는 이의 약제학적 허용가능한 염, 및 로자탄또는 이의 약제학적 허용가능한 염을 함유하는 약제학적조성물
AU2010251194B2 (en)	2009-05-20	2016-02-25	Boehringer Ingelheim Vetmedica Gmbh	Pharmaceutical oral telmisartan solution
EP3996709A1 (de)	2019-07-09	2022-05-18	Boehringer Ingelheim Vetmedica GmbH	Telmisartan zur behandlung von bluthochdruck bei hunden

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL58849A (en) *	1978-12-11	1983-03-31	Merck & Co Inc	Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US5120548A (en) *	1989-11-07	1992-06-09	Merck & Co., Inc.	Swelling modulated polymeric drug delivery device
ES2097208T3 (es) *	1990-05-11	1997-04-01	Pfizer	Composiciones y procedimientos terapeuticos y sinergicos.
EP0565634B1 (de) *	1990-12-14	1999-03-17	Smithkline Beecham Corporation	Angiotensin-ii-rezeptor blockierende zusammensetzungen
AU653793B2 (en) *	1991-01-30	1994-10-13	Alza Corporation	Osmotic device for delayed delivery of agent
CZ227093A3 (en) *	1991-04-29	1994-03-16	Merck & Co Inc	Mixture suitable for the preparation of tablets by direct moulding
US5492904A (en) *	1991-05-15	1996-02-20	E. I. Du Pont De Nemours And Company	Composition of angiotensin-II receptor antagonists and calcium channel blockers
US5160744A (en) *	1991-06-27	1992-11-03	Alza Corporation	Verapmil therapy
US5266583A (en) *	1992-09-01	1993-11-30	Merck & Co., Inc.	Angitotensin II antagonist
EP0629408A1 (de) *	1993-06-16	1994-12-21	LABORATOIRES MERCK, SHARP & DOHME-CHIBRET	Kombination von Angiotensin-Converting-Enzyme Hemmern mit A-II-Antagonisten
EP0754042A4 (de) *	1994-03-29	2004-06-23	Merck & Co Inc	Behandlung von atherosklerose mit imidazolen, die den angiotensin ii-rezeptor blockieren

1997
- 1997-06-20 CA CA002257946A patent/CA2257946A1/en not_active Abandoned
- 1997-06-20 AU AU35710/97A patent/AU724576B2/en not_active Ceased
- 1997-06-20 JP JP10503194A patent/JP2000513356A/ja active Pending
- 1997-06-20 AT AT97932188T patent/ATE216881T1/de not_active IP Right Cessation
- 1997-06-20 WO PCT/US1997/010372 patent/WO1997049392A1/en not_active Ceased
- 1997-06-20 DE DE69712338T patent/DE69712338T2/de not_active Expired - Fee Related
- 1997-06-20 EP EP97932188A patent/EP0910375B1/de not_active Expired - Lifetime
- 1997-06-20 ES ES97932188T patent/ES2175437T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0910375A1 (de)	1999-04-28
WO1997049392A1 (en)	1997-12-31
EP0910375A4 (de)	1999-09-01
DE69712338T2 (de)	2002-11-07
AU3571097A (en)	1998-01-14
DE69712338D1 (de)	2002-06-06
CA2257946A1 (en)	1997-12-31
JP2000513356A (ja)	2000-10-10
EP0910375B1 (de)	2002-05-02
AU724576B2 (en)	2000-09-28
ES2175437T3 (es)	2002-11-16

Similar Documents

Publication	Publication Date	Title
ATE396205T1 (de)	2008-06-15	Die verwendung von peptiden von il-2 und peptid- derivaten als therapeutische wirkstoffe
ATE234112T1 (de)	2003-03-15	Periphäre verabreichung von glp-1 analogen und derivate zur reguleirung der fettleibigkeit
MX9804597A (es)	1998-10-31	Derivados de bencimidazol sustituidos por naftilo como anticoagulantes.
ATE280826T1 (de)	2004-11-15	Cc-chemokinzeptor c-c ckr-5, dessen derivate und verwendungen
BR9506820A (pt)	1997-09-09	Derivados de 4-amino de ácido micofenólico
DE69526120D1 (de)	2002-05-02	Verwendung von nebivolol als anti-atherogenisches mittel
BG97068A (bg)	1993-12-24	Фармацевтичен състав и метод за постигане на терапевтичен ефект
ATE239474T1 (de)	2003-05-15	Verwendung von levobupivacain
DE69712338D1 (de)	2002-06-06	Zusammensetzung auf basis von enalapril und losartan
ATE338771T1 (de)	2006-09-15	Antagonisten des intestinotrophen glp-2 peptides
IL125124A0 (en)	1999-01-26	Dimeric forms of the protein fapalpha and uses thereof
DK0745075T3 (da)	2002-03-04	6-Substituerede mycophenolsyrederivater med immunsuppressiv virkning
PT1017659E (pt)	2005-09-30	Tetra-hidronaftalenos substituidos e compostos analogos
PT902789E (pt)	2002-07-31	Derivados de androsteno
FI971420A0 (fi)	1997-04-04	Menetelmä diabetes mellituksen hoitamiseksi KGF:ää käyttämällä
BR9913564A (pt)	2001-05-22	Tratamento de angiopatias microvasculares
AU682166B2 (en)	1997-09-25	Synergising association having an antagonist effect on NK1 and NK2 receptors
BG102667A (en)	1999-02-26	Diosgenine-containing composition
DE69309790D1 (de)	1997-05-22	Cyclopentanperhydrophenanthren-17-beta-(3-Furyl)-3-Derivate und pharmazeutische Präparate davon, zur Behandlung von Kardiovaskulär-Erkrankungen
TR199801988T2 (xx)	2000-08-21	Kalp yetmezli�inin endotelin antagonistleri ile tedavisi i�in y�ntem.
ATE210126T1 (de)	2001-12-15	4-amino-6-substituierte mycophenolsäurederivate mit immunsuppressiver wirkung
DE59708511D1 (de)	2002-11-21	Verwendung von 7-(1-aminomethyl-2-oxa-7-aza-bicyclo 3.3.0]oct-7-yl)-chinoloncarbonsäure- und -naphthyridoncarbonsäure-derivaten zur therapie von helicobacter-pylori-infektionen und den damit assoziierten gastroduodenalen erkrankungen
LV12149A (lv)	1998-10-20	5-Aizvietoti mikofenolskabes 4-aminoatvasinajumi
DK0720597T3 (da)	1998-10-07	Triarylethylenderivater til terapeutisk anvendelse
BG103859A (en)	2000-07-31	The use of 1-ar(alk)yl-imidazolin-2-on for the treatment of fear and stress conditions

Legal Events

Date	Code	Title	Description
2002-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties