ATE217186T1 - Wässrige emulsion mit kontrollierter freisetzung - Google Patents

Wässrige emulsion mit kontrollierter freisetzung

Info

Publication number: ATE217186T1
Authority: AT; Austria
Prior art keywords: oil; weight percent; total composition; value; water
Prior art date: 1994-06-21

Application number

AT95924647T

Other languages

English (en)

Inventor

S Esmail Tabibi

Robert W Mendes

Nitin P Pathak

Original Assignee

Ascent Pediatrics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-06-21

Filing date

1995-06-21

Publication date

2002-05-15

1995-06-21 Application filed by Ascent Pediatrics Inc filed Critical Ascent Pediatrics Inc

2002-05-15 Application granted granted Critical

2002-05-15 Publication of ATE217186T1 publication Critical patent/ATE217186T1/de

Links

239000000839 emulsion Substances 0.000 title abstract 3
238000013270 controlled release Methods 0.000 title abstract 2
239000000203 mixture Substances 0.000 abstract 4
239000003995 emulsifying agent Substances 0.000 abstract 2
239000011159 matrix material Substances 0.000 abstract 2
238000005191 phase separation Methods 0.000 abstract 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000000354 decomposition reaction Methods 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000000787 lecithin Substances 0.000 abstract 1
229940067606 lecithin Drugs 0.000 abstract 1
235000010445 lecithin Nutrition 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000002844 melting Methods 0.000 abstract 1
230000008018 melting Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000007764 o/w emulsion Substances 0.000 abstract 1
239000002245 particle Substances 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Optics & Photonics (AREA)
Nanotechnology (AREA)
Biomedical Technology (AREA)
Physics & Mathematics (AREA)
Medicinal Preparation (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
General Preparation And Processing Of Foods (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Colloid Chemistry (AREA)

AT95924647T 1994-06-21 1995-06-21 Wässrige emulsion mit kontrollierter freisetzung ATE217186T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US26327794A	1994-06-21	1994-06-21
US08/491,626 US5672358A (en)	1994-06-21	1995-06-19	Controlled release aqueous emulsion
PCT/US1995/007908 WO1995035096A1 (en)	1994-06-21	1995-06-21	Controlled release aqueous emulsion

Publications (1)

Publication Number	Publication Date
ATE217186T1 true ATE217186T1 (de)	2002-05-15

Family

ID=26949751

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95924647T ATE217186T1 (de)	1994-06-21	1995-06-21	Wässrige emulsion mit kontrollierter freisetzung

Country Status (11)

Country	Link
US (1)	US5672358A (de)
EP (1)	EP0773780B1 (de)
JP (1)	JP3583435B2 (de)
AT (1)	ATE217186T1 (de)
AU (1)	AU706516B2 (de)
CA (1)	CA2193497C (de)
DE (1)	DE69526655T2 (de)
DK (1)	DK0773780T3 (de)
ES (1)	ES2176333T3 (de)
WO (1)	WO1995035096A1 (de)
ZA (1)	ZA955153B (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2751222B1 (fr) *	1996-07-16	1998-10-09	Capsulis	Compositions contenant au moins un acide nucleique et leurs applications dans le domaine biomedical, en particulier en therapie genique
GB9625589D0 (en) *	1996-12-10	1997-01-29	Boots Co Plc	Therapeutic agents
US7541020B2 (en) *	1997-05-08	2009-06-02	Corixa Corporation	Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors
US5891476A (en) *	1997-12-22	1999-04-06	Reo; Joe P.	Tastemasked pharmaceutical system
US6682758B1 (en)	1998-12-22	2004-01-27	The United States Of America As Represented By The Department Of Health And Human Services	Water-insoluble drug delivery system
IL146567A0 (en) *	1999-06-04	2002-07-25	Skyepharma Inc	Oil-core particles containing a hydrophobic core material and hydrophobic drug and method for the preparation thereof
US6703319B1 (en) *	1999-06-17	2004-03-09	Micron Technology, Inc.	Compositions and methods for removing etch residue
US7153525B1 (en)	2000-03-22	2006-12-26	The University Of Kentucky Research Foundation	Microemulsions as precursors to solid nanoparticles
CA2410469A1 (en) *	2001-03-27	2002-10-03	R.P. Scherer Technologies, Inc.	Improved forms of pharmaceutically active agents and method for manufacture thereof
US20040132823A1 (en) *	2001-11-02	2004-07-08	Leo Pavliv	Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
US7763663B2 (en) *	2001-12-19	2010-07-27	University Of Massachusetts	Polysaccharide-containing block copolymer particles and uses thereof
US20030139582A1 (en) *	2002-01-17	2003-07-24	Wang Kai Hua	Composition containing biologically active polypeptides suitable for the oral administration
US20030232097A1 (en) *	2002-06-17	2003-12-18	Strides Inc.	Oily wax matrix suspension formulation comprising ibuprofen free acid and potassium salt of ibuprofen
US20040213837A1 (en) *	2002-08-05	2004-10-28	Sankaram Mantripragada	Oil-core compositions for the sustained release of hydrophobic drugs
WO2004053056A2 (en) *	2002-09-24	2004-06-24	University Of Kentucky Research Foundation	Nanoparticle-based vaccine delivery system containing adjuvant
CA2430541A1 (en) *	2003-05-30	2004-11-30	Isomers Laboratories	Cosmetic
KR101148013B1 (ko) *	2003-10-27	2012-07-05	다니스코 유에스 인크.	국소용 제제, 및 활성제를 기재로 전달하는 방법
US8318210B2 (en)	2005-02-28	2012-11-27	Neos Therapeutics, Lp	Compositions and methods of making sustained release liquid formulations
PL1879466T5 (pl) *	2005-03-04	2016-07-29	Dsm Ip Assets Bv	Spożywcza cząsteczkowa kompozycja lipidowa
KR20130079645A (ko)	2005-07-18	2013-07-10	유니버시티 오브 메사츄세츠 로웰	나노에멀젼 조성물 및 이의 제조 및 사용 방법
SG140723A1 (en) *	2005-09-16	2008-04-28	Dsm Ip Assets Bv	Particulate lipid pharmaceutical composition
US9486408B2 (en)	2005-12-01	2016-11-08	University Of Massachusetts Lowell	Botulinum nanoemulsions
CN101374498A (zh)	2005-12-01	2009-02-25	麻萨诸塞州洛厄尔大学	肉毒杆菌纳米乳液
JP2009533471A (ja) *	2006-04-12	2009-09-17	バイオデル，インコーポレイテッド	即効型および長時間作用型組合せインスリン製剤
US20080118570A1 (en) *	2006-11-20	2008-05-22	Zhi Liu	Polymer coated drug-ion exchange resins and methods
SG10201607909WA (en)	2006-12-01	2016-11-29	Anterios Inc	Peptide nanoparticles and uses therefor
WO2008070538A2 (en)	2006-12-01	2008-06-12	Anterios, Inc.	Micellar nanoparticles comprising botulinum toxin
CN101765423B (zh)	2007-05-31	2014-08-06	安特里奥公司	核酸纳米粒子和其用途
GB201006215D0 (en) *	2010-04-14	2010-06-02	Ayanda As	Composition
US20120015913A1 (en) *	2010-07-15	2012-01-19	Delansorne Remi	Formulations of 14-EPI-Analogues of Vitamin D
CA2809022C (en) *	2010-08-20	2017-01-03	Dr. Reddy`S Laboratories, Inc.	Phospholipid depot
JP6121796B2 (ja) *	2012-05-23	2017-04-26	キユーピー株式会社	脂肪乳剤および医薬品組成物中の非ステロイド性抗炎症薬の含有量を高める方法
EP3541358A1 (de)	2016-11-21	2019-09-25	Eirion Therapeutics, Inc.	Transdermale verabreichung von grossen wirkstoffen
US11278493B2 (en)	2018-12-10	2022-03-22	EternaTear, Inc.	Ophthalmic formulations providing durable ocular lubrication
US11679078B1 (en)	2022-03-08	2023-06-20	EternaTear, Inc.	Ophthalmic formulations and related methods
US11471475B1 (en)	2022-03-08	2022-10-18	Ralph P. Stone	Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE58110B1 (en) *	1984-10-30	1993-07-14	Elan Corp Plc	Controlled release powder and process for its preparation
US5188837A (en) *	1989-11-13	1993-02-23	Nova Pharmaceutical Corporation	Lipsopheres for controlled delivery of substances
AU658608B2 (en) *	1991-03-25	1995-04-27	Astellas Pharma Europe B.V.	Topical preparation containing a suspension of solid lipid particles
WO1992018147A1 (en) *	1991-04-19	1992-10-29	Affinity Biotech, Inc.	Convertible microemulsion formulations
NZ243721A (en) *	1991-07-26	1994-11-25	Smithkline Beecham Corp	Self-emulsifying microemulsion comprising water soluble drug, high hlb surfactant and a lipophilic phase containing fatty acid triglyceride and a low hlb surfactant
US5576016A (en) *	1993-05-18	1996-11-19	Pharmos Corporation	Solid fat nanoemulsions as drug delivery vehicles

1995
- 1995-06-19 US US08/491,626 patent/US5672358A/en not_active Expired - Lifetime
- 1995-06-21 EP EP95924647A patent/EP0773780B1/de not_active Expired - Lifetime
- 1995-06-21 ZA ZA955153A patent/ZA955153B/xx unknown
- 1995-06-21 CA CA002193497A patent/CA2193497C/en not_active Expired - Fee Related
- 1995-06-21 AT AT95924647T patent/ATE217186T1/de not_active IP Right Cessation
- 1995-06-21 ES ES95924647T patent/ES2176333T3/es not_active Expired - Lifetime
- 1995-06-21 AU AU29070/95A patent/AU706516B2/en not_active Ceased
- 1995-06-21 DK DK95924647T patent/DK0773780T3/da active
- 1995-06-21 DE DE69526655T patent/DE69526655T2/de not_active Expired - Fee Related
- 1995-06-21 WO PCT/US1995/007908 patent/WO1995035096A1/en not_active Ceased
- 1995-06-21 JP JP50259396A patent/JP3583435B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0773780A1 (de)	1997-05-21
AU706516B2 (en)	1999-06-17
ES2176333T3 (es)	2002-12-01
DE69526655T2 (de)	2002-12-05
EP0773780B1 (de)	2002-05-08
CA2193497C (en)	2000-10-17
US5672358A (en)	1997-09-30
AU2907095A (en)	1996-01-15
ZA955153B (en)	1996-05-07
JP2002510279A (ja)	2002-04-02
DE69526655D1 (de)	2002-06-13
DK0773780T3 (da)	2002-09-09
JP3583435B2 (ja)	2004-11-04
CA2193497A1 (en)	1995-12-28
EP0773780A4 (de)	1998-09-30
WO1995035096A1 (en)	1995-12-28

Legal Events

Date	Code	Title	Description
2002-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69526655D1 (de)	2002-06-13	Wässrige emulsion mit kontrollierter freisetzung
ATE191641T1 (de)	2000-04-15	Emulsionen im submikron-bereich als vehikel zur arzneistoffverabreichung am auge
ES2186802T3 (es)	2003-05-16	Microemulsiones destinadas a usarse como vehiculos para la alimentacion de compuestos activos.
AU650946B2 (en)	1994-07-07	Analgesic compositions
FR2767064B1 (fr)	1999-11-12	Procede de liberation d'un principe actif contenu dans une emulsion multiple
EP0272374A3 (de)	1990-09-05	Bioaktive Zusammensetzungen und Verfahren zu deren Herstellung und Verwendung
UY23276A1 (es)	1992-01-15	Procedimiento para preparar microcapsulas diseñadas para una liberación sostenida
UA27698C2 (uk)	2000-10-16	Спосіб одержання мікрокапсули поліпептиду
KR870000921A (ko)	1987-03-10	마이크로에멀젼 조성물
IE870283L (en)	1988-08-03	Micro emulsions
KR20180121251A (ko)	2018-11-07	다층상 화장료 조성물
EP0284026A3 (de)	1991-02-06	Verfahren zur Zubereitung einer emulgierten Fett-Zusammensetzung
EP0626850A4 (de)	1995-07-26	Trockene zusammensetzung zur herstellung von emulsionen im submikron-bereich.
KR930001929A (ko)	1993-02-22	안과용 조성물
HU213669B (en)	1997-09-29	Preparation suitable for local treatment and comprising suspension of solid lipid particles, as well as process for producing same and pharmaceutical compositions for local treatment of body
Weingarten et al.	1991	Interactions of a non-ionic ABA copolymer surfactant with phospholipid monolayers: possible relevance to emulsion stabilization
KR960700039A (ko)	1996-01-19	β-시클로덱스트린 유도체 및 탄산 탈수효소 저해제로 이루어진 안과용 국소 투여 조성물(Topical Compositions for the Eye Comprising a β-cyclodextrin Derivative and a Carbonic Anhydrase Inhibitor)
IE890415L (en)	1989-08-10	Emulsion compositions including amphipathic emulsifying agents
CZ59995A3 (en)	1995-09-13	Antivirally active pharmaceutical oil-in water emulsion containing 9/(2-hydroxyethoxy)methyl/quanine (acyclovirus) or salts or esters thereof
FR2706298B1 (fr)	1995-08-11	Composition cosmétique ou dermatologique sous forme d'une émulsion huile-dans-l'eau stable contenant au moins une huile végétale constituée d'au moins 40% de triglycérides d'acide linoléique.
TR199901716T2 (en)	1999-09-21	So�utucu ya�lama em�lsiyonu.
RU2005100961A (ru)	2005-08-10	Композиция эмульсий для антиперспирантов
ATE270869T1 (de)	2004-07-15	ZUSAMMENSETZUNG MIT KONTINUIERLICHER WÄSSERIGER PHASE, DIE L-2-OXOTHIAZOLIDIN- 4-CARBONSÄURE ENTHÄLTß.
JP2011126810A (ja)	2011-06-30	水中油型乳化皮膚化粧料
YU13302A (sh)	2005-03-15	Parenteralna emulzija cisplatina