ES2176333T3 - Composicion de liberacion controlada acuosa. - Google Patents

Composicion de liberacion controlada acuosa.

Info

Publication number
ES2176333T3
ES2176333T3 ES95924647T ES95924647T ES2176333T3 ES 2176333 T3 ES2176333 T3 ES 2176333T3 ES 95924647 T ES95924647 T ES 95924647T ES 95924647 T ES95924647 T ES 95924647T ES 2176333 T3 ES2176333 T3 ES 2176333T3
Authority
ES
Spain
Prior art keywords
oil
weight percent
total composition
composition
value
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95924647T
Other languages
English (en)
Inventor
S Esmail Tabibi
Robert W Mendes
Nitin P Pathak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicis Pediatrics Inc
Original Assignee
Medicis Pediatrics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicis Pediatrics Inc filed Critical Medicis Pediatrics Inc
Application granted granted Critical
Publication of ES2176333T3 publication Critical patent/ES2176333T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Colloid Chemistry (AREA)

Abstract

SE MUESTRA UNA EMULSION ACUOSA DE LIBERACION CONTROLADA, ASI COMO SU METODO DE FABRICACION Y USO COMO VEHICULO PARA SUMINISTRAR MEDICAMENTOS EN FORMA LIQUIDA. LA EMULSION CONTEMPLADA INCLUYE UNA CERA QUE CONTIENE UNA EMULSION DE ACEITE EN AGUA QUE TIENE UN TAMAÑO PARTICULAR MEDIO DE ENTRE 100NM. Y 250NM. APROXIMADAMENTE, UN VALOR PH COMPRENDIDO ENTRE 4.5 Y 8.0 Y UNA VISCOSIDAD A 20-25 C DE 1 A 1000 CPS. APROXIMADAMENTE. LAS FASES DE ACEITE Y AGUA SON EMULSIONADAS MEDIANTE UN AGENTE EMULSIONANTE QUE PERMITE LA LIBERACION DE LA SEPARACION DE FASE A UN VALOR PH DE ENTRE 4.5 Y 8 APROXIMADAMENTE, PERMITIENDO TAMBIEN LA SEPARACION DE FASE A UN VALOR PH INFERIOR 2.0.
ES95924647T 1994-06-21 1995-06-21 Composicion de liberacion controlada acuosa. Expired - Lifetime ES2176333T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26327794A 1994-06-21 1994-06-21
US08/491,626 US5672358A (en) 1994-06-21 1995-06-19 Controlled release aqueous emulsion

Publications (1)

Publication Number Publication Date
ES2176333T3 true ES2176333T3 (es) 2002-12-01

Family

ID=26949751

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95924647T Expired - Lifetime ES2176333T3 (es) 1994-06-21 1995-06-21 Composicion de liberacion controlada acuosa.

Country Status (11)

Country Link
US (1) US5672358A (es)
EP (1) EP0773780B1 (es)
JP (1) JP3583435B2 (es)
AT (1) ATE217186T1 (es)
AU (1) AU706516B2 (es)
CA (1) CA2193497C (es)
DE (1) DE69526655T2 (es)
DK (1) DK0773780T3 (es)
ES (1) ES2176333T3 (es)
WO (1) WO1995035096A1 (es)
ZA (1) ZA955153B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2751222B1 (fr) * 1996-07-16 1998-10-09 Capsulis Compositions contenant au moins un acide nucleique et leurs applications dans le domaine biomedical, en particulier en therapie genique
GB9625589D0 (en) * 1996-12-10 1997-01-29 Boots Co Plc Therapeutic agents
US7541020B2 (en) * 1997-05-08 2009-06-02 Corixa Corporation Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors
US5891476A (en) * 1997-12-22 1999-04-06 Reo; Joe P. Tastemasked pharmaceutical system
US6682758B1 (en) 1998-12-22 2004-01-27 The United States Of America As Represented By The Department Of Health And Human Services Water-insoluble drug delivery system
NZ515644A (en) * 1999-06-04 2004-12-24 Skyepharma Inc Oil-core compositions for the sustained release of hydrophobic drugs
US6703319B1 (en) * 1999-06-17 2004-03-09 Micron Technology, Inc. Compositions and methods for removing etch residue
US7153525B1 (en) * 2000-03-22 2006-12-26 The University Of Kentucky Research Foundation Microemulsions as precursors to solid nanoparticles
CA2410469A1 (en) * 2001-03-27 2002-10-03 R.P. Scherer Technologies, Inc. Improved forms of pharmaceutically active agents and method for manufacture thereof
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
US7763663B2 (en) * 2001-12-19 2010-07-27 University Of Massachusetts Polysaccharide-containing block copolymer particles and uses thereof
US20030139582A1 (en) * 2002-01-17 2003-07-24 Wang Kai Hua Composition containing biologically active polypeptides suitable for the oral administration
US20030232097A1 (en) * 2002-06-17 2003-12-18 Strides Inc. Oily wax matrix suspension formulation comprising ibuprofen free acid and potassium salt of ibuprofen
US20040213837A1 (en) * 2002-08-05 2004-10-28 Sankaram Mantripragada Oil-core compositions for the sustained release of hydrophobic drugs
US20060189554A1 (en) * 2002-09-24 2006-08-24 Russell Mumper Nanoparticle-Based vaccine delivery system containing adjuvant
CA2430541A1 (en) * 2003-05-30 2004-11-30 Isomers Laboratories Cosmetic
CA2543940A1 (en) * 2003-10-27 2005-05-19 Dow Corning Corporation Preparations for topical application and methods of delivering an active agent to a substrate
US8318210B2 (en) 2005-02-28 2012-11-27 Neos Therapeutics, Lp Compositions and methods of making sustained release liquid formulations
JP2008531045A (ja) * 2005-03-04 2008-08-14 ディーエスエム アイピー アセッツ ビー．ブイ． 食品用微粒子状脂質組成物
US20080274195A1 (en) 2005-07-18 2008-11-06 University Of Massachusetts Lowell Compositions and Methods for Making and Using Nanoemulsions
WO2007032727A1 (en) * 2005-09-16 2007-03-22 Dsm Ip Assets B.V. Particulate lipid pharmaceutical composition
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
KR102110379B1 (ko) 2005-12-01 2020-05-14 유니버시티 오브 메사츄세츠 로웰 보툴리눔 나노에멀젼
EP2012817A2 (en) * 2006-04-12 2009-01-14 Biodel, Inc. Rapid acting and long acting insulin combination formulations
US20080118570A1 (en) * 2006-11-20 2008-05-22 Zhi Liu Polymer coated drug-ion exchange resins and methods
SG177184A1 (en) 2006-12-01 2012-01-30 Anterios Inc Amphiphilic entity nanoparticles
SG179457A1 (en) 2006-12-01 2012-04-27 Anterios Inc Peptide nanoparticles and uses therefor
CN101765423B (zh) 2007-05-31 2014-08-06 安特里奥公司 核酸纳米粒子和其用途
GB201006215D0 (en) * 2010-04-14 2010-06-02 Ayanda As Composition
US20120015913A1 (en) * 2010-07-15 2012-01-19 Delansorne Remi Formulations of 14-EPI-Analogues of Vitamin D
WO2012023955A1 (en) * 2010-08-20 2012-02-23 Dr. Reddy's Laboratories, Ltd. Phospholipid depot
JP6121796B2 (ja) * 2012-05-23 2017-04-26 キユーピー株式会社 脂肪乳剤および医薬品組成物中の非ステロイド性抗炎症薬の含有量を高める方法
MX2019005833A (es) 2016-11-21 2019-10-30 Eirion Therapeutics Inc Administracion transdermica de agentes grandes.
US11278493B2 (en) 2018-12-10 2022-03-22 EternaTear, Inc. Ophthalmic formulations providing durable ocular lubrication
US11471475B1 (en) 2022-03-08 2022-10-18 Ralph P. Stone Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery
US11679078B1 (en) 2022-03-08 2023-06-20 EternaTear, Inc. Ophthalmic formulations and related methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US5188837A (en) * 1989-11-13 1993-02-23 Nova Pharmaceutical Corporation Lipsopheres for controlled delivery of substances
AU658608B2 (en) * 1991-03-25 1995-04-27 Astellas Pharma Europe B.V. Topical preparation containing a suspension of solid lipid particles
AU668509B2 (en) * 1991-04-19 1996-05-09 Affinity Biotech, Inc. Convertible microemulsion formulations
AU667483B2 (en) * 1991-07-26 1996-03-28 Smithkline Beecham Corporation W/O microemulsions
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles

Also Published As

Publication number Publication date
ATE217186T1 (de) 2002-05-15
ZA955153B (en) 1996-05-07
EP0773780B1 (en) 2002-05-08
EP0773780A4 (en) 1998-09-30
DK0773780T3 (da) 2002-09-09
JP3583435B2 (ja) 2004-11-04
AU706516B2 (en) 1999-06-17
DE69526655D1 (de) 2002-06-13
CA2193497A1 (en) 1995-12-28
JP2002510279A (ja) 2002-04-02
US5672358A (en) 1997-09-30
WO1995035096A1 (en) 1995-12-28
CA2193497C (en) 2000-10-17
EP0773780A1 (en) 1997-05-21
DE69526655T2 (de) 2002-12-05
AU2907095A (en) 1996-01-15

Similar Documents

Publication Publication Date Title
ES2176333T3 (es) Composicion de liberacion controlada acuosa.
ES2186802T3 (es) Microemulsiones destinadas a usarse como vehiculos para la alimentacion de compuestos activos.
AU650946B2 (en) Analgesic compositions
KR920017642A (ko) 고체 지질 입자의 현탁액을 함유한 국소제제
FR2561916B1 (fr) Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau
CA2142103A1 (en) Submicron emulsions as ocular drug delivery vehicles
EP0272374A3 (en) Bioactive compositions and methods of producing and using same
FR2767064B1 (fr) Procede de liberation d'un principe actif contenu dans une emulsion multiple
ZA9410149B (en) Composition
EP0284026A3 (en) Process for preparing emulsified fat composition
KR930001929A (ko) 안과용 조성물
JP2001010925A5 (es)
FR2706298B1 (fr) Composition cosmétique ou dermatologique sous forme d'une émulsion huile-dans-l'eau stable contenant au moins une huile végétale constituée d'au moins 40% de triglycérides d'acide linoléique.
DE68912150D1 (de) Amphipatische Emulgiermittel enthaltende Emulsionzusammensetzungen.
CZ59995A3 (en) Antivirally active pharmaceutical oil-in water emulsion containing 9/(2-hydroxyethoxy)methyl/quanine (acyclovirus) or salts or esters thereof
RU2005100961A (ru) Композиция эмульсий для антиперспирантов
JP5588164B2 (ja) 水中油型乳化皮膚化粧料
FR2400889A1 (fr) Procede de preparation d'emulsions eau-dans-l'huile ou huile-dans-l'eau a faible teneur en eau et contenant de la poudre de polyethylene, et emulsions ainsi obtenues
ATE270869T1 (de) ZUSAMMENSETZUNG MIT KONTINUIERLICHER WÄSSERIGER PHASE, DIE L-2-OXOTHIAZOLIDIN- 4-CARBONSÄURE ENTHÄLTß.
WO2001007058A3 (en) Parenteral cisplatin emulsion
Osborne et al. Role of stratum corneum lipids as moisture retaining agent
WO1996032923A3 (de) Antitranspirantien
IL98801A (en) Water dispersible gel formulations
JPH07277988A (ja) 局所用掻痒除去、治療剤
ES2059827T3 (es) Emulsion para administracion parenteral.