ES2176333T3 - Composicion de liberacion controlada acuosa. - Google Patents

Composicion de liberacion controlada acuosa.

Info

Publication number
ES2176333T3
ES2176333T3 ES95924647T ES95924647T ES2176333T3 ES 2176333 T3 ES2176333 T3 ES 2176333T3 ES 95924647 T ES95924647 T ES 95924647T ES 95924647 T ES95924647 T ES 95924647T ES 2176333 T3 ES2176333 T3 ES 2176333T3
Authority
ES
Spain
Prior art keywords
oil
weight percent
total composition
composition
value
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95924647T
Other languages
English (en)
Inventor
S Esmail Tabibi
Robert W Mendes
Nitin P Pathak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicis Pediatrics Inc
Original Assignee
Medicis Pediatrics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicis Pediatrics Inc filed Critical Medicis Pediatrics Inc
Application granted granted Critical
Publication of ES2176333T3 publication Critical patent/ES2176333T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Colloid Chemistry (AREA)

Abstract

SE MUESTRA UNA EMULSION ACUOSA DE LIBERACION CONTROLADA, ASI COMO SU METODO DE FABRICACION Y USO COMO VEHICULO PARA SUMINISTRAR MEDICAMENTOS EN FORMA LIQUIDA. LA EMULSION CONTEMPLADA INCLUYE UNA CERA QUE CONTIENE UNA EMULSION DE ACEITE EN AGUA QUE TIENE UN TAMAÑO PARTICULAR MEDIO DE ENTRE 100NM. Y 250NM. APROXIMADAMENTE, UN VALOR PH COMPRENDIDO ENTRE 4.5 Y 8.0 Y UNA VISCOSIDAD A 20-25 C DE 1 A 1000 CPS. APROXIMADAMENTE. LAS FASES DE ACEITE Y AGUA SON EMULSIONADAS MEDIANTE UN AGENTE EMULSIONANTE QUE PERMITE LA LIBERACION DE LA SEPARACION DE FASE A UN VALOR PH DE ENTRE 4.5 Y 8 APROXIMADAMENTE, PERMITIENDO TAMBIEN LA SEPARACION DE FASE A UN VALOR PH INFERIOR 2.0.
ES95924647T 1994-06-21 1995-06-21 Composicion de liberacion controlada acuosa. Expired - Lifetime ES2176333T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26327794A 1994-06-21 1994-06-21
US08/491,626 US5672358A (en) 1994-06-21 1995-06-19 Controlled release aqueous emulsion

Publications (1)

Publication Number Publication Date
ES2176333T3 true ES2176333T3 (es) 2002-12-01

Family

ID=26949751

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95924647T Expired - Lifetime ES2176333T3 (es) 1994-06-21 1995-06-21 Composicion de liberacion controlada acuosa.

Country Status (11)

Country Link
US (1) US5672358A (es)
EP (1) EP0773780B1 (es)
JP (1) JP3583435B2 (es)
AT (1) ATE217186T1 (es)
AU (1) AU706516B2 (es)
CA (1) CA2193497C (es)
DE (1) DE69526655T2 (es)
DK (1) DK0773780T3 (es)
ES (1) ES2176333T3 (es)
WO (1) WO1995035096A1 (es)
ZA (1) ZA955153B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2751222B1 (fr) * 1996-07-16 1998-10-09 Capsulis Compositions contenant au moins un acide nucleique et leurs applications dans le domaine biomedical, en particulier en therapie genique
GB9625589D0 (en) * 1996-12-10 1997-01-29 Boots Co Plc Therapeutic agents
US7541020B2 (en) * 1997-05-08 2009-06-02 Corixa Corporation Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors
US5891476A (en) * 1997-12-22 1999-04-06 Reo; Joe P. Tastemasked pharmaceutical system
US6682758B1 (en) 1998-12-22 2004-01-27 The United States Of America As Represented By The Department Of Health And Human Services Water-insoluble drug delivery system
IL146567A0 (en) * 1999-06-04 2002-07-25 Skyepharma Inc Oil-core particles containing a hydrophobic core material and hydrophobic drug and method for the preparation thereof
US6703319B1 (en) * 1999-06-17 2004-03-09 Micron Technology, Inc. Compositions and methods for removing etch residue
US7153525B1 (en) 2000-03-22 2006-12-26 The University Of Kentucky Research Foundation Microemulsions as precursors to solid nanoparticles
CA2410469A1 (en) * 2001-03-27 2002-10-03 R.P. Scherer Technologies, Inc. Improved forms of pharmaceutically active agents and method for manufacture thereof
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
US7763663B2 (en) * 2001-12-19 2010-07-27 University Of Massachusetts Polysaccharide-containing block copolymer particles and uses thereof
US20030139582A1 (en) * 2002-01-17 2003-07-24 Wang Kai Hua Composition containing biologically active polypeptides suitable for the oral administration
US20030232097A1 (en) * 2002-06-17 2003-12-18 Strides Inc. Oily wax matrix suspension formulation comprising ibuprofen free acid and potassium salt of ibuprofen
US20040213837A1 (en) * 2002-08-05 2004-10-28 Sankaram Mantripragada Oil-core compositions for the sustained release of hydrophobic drugs
WO2004053056A2 (en) * 2002-09-24 2004-06-24 University Of Kentucky Research Foundation Nanoparticle-based vaccine delivery system containing adjuvant
CA2430541A1 (en) * 2003-05-30 2004-11-30 Isomers Laboratories Cosmetic
KR101148013B1 (ko) * 2003-10-27 2012-07-05 다니스코 유에스 인크. 국소용 제제, 및 활성제를 기재로 전달하는 방법
US8318210B2 (en) 2005-02-28 2012-11-27 Neos Therapeutics, Lp Compositions and methods of making sustained release liquid formulations
PL1879466T5 (pl) * 2005-03-04 2016-07-29 Dsm Ip Assets Bv Spożywcza cząsteczkowa kompozycja lipidowa
KR20130079645A (ko) 2005-07-18 2013-07-10 유니버시티 오브 메사츄세츠 로웰 나노에멀젼 조성물 및 이의 제조 및 사용 방법
SG140723A1 (en) * 2005-09-16 2008-04-28 Dsm Ip Assets Bv Particulate lipid pharmaceutical composition
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
CN101374498A (zh) 2005-12-01 2009-02-25 麻萨诸塞州洛厄尔大学 肉毒杆菌纳米乳液
JP2009533471A (ja) * 2006-04-12 2009-09-17 バイオデル， インコーポレイテッド 即効型および長時間作用型組合せインスリン製剤
US20080118570A1 (en) * 2006-11-20 2008-05-22 Zhi Liu Polymer coated drug-ion exchange resins and methods
SG10201607909WA (en) 2006-12-01 2016-11-29 Anterios Inc Peptide nanoparticles and uses therefor
WO2008070538A2 (en) 2006-12-01 2008-06-12 Anterios, Inc. Micellar nanoparticles comprising botulinum toxin
CN101765423B (zh) 2007-05-31 2014-08-06 安特里奥公司 核酸纳米粒子和其用途
GB201006215D0 (en) * 2010-04-14 2010-06-02 Ayanda As Composition
US20120015913A1 (en) * 2010-07-15 2012-01-19 Delansorne Remi Formulations of 14-EPI-Analogues of Vitamin D
CA2809022C (en) * 2010-08-20 2017-01-03 Dr. Reddy`S Laboratories, Inc. Phospholipid depot
JP6121796B2 (ja) * 2012-05-23 2017-04-26 キユーピー株式会社 脂肪乳剤および医薬品組成物中の非ステロイド性抗炎症薬の含有量を高める方法
EP3541358A1 (en) 2016-11-21 2019-09-25 Eirion Therapeutics, Inc. Transdermal delivery of large agents
US11278493B2 (en) 2018-12-10 2022-03-22 EternaTear, Inc. Ophthalmic formulations providing durable ocular lubrication
US11679078B1 (en) 2022-03-08 2023-06-20 EternaTear, Inc. Ophthalmic formulations and related methods
US11471475B1 (en) 2022-03-08 2022-10-18 Ralph P. Stone Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US5188837A (en) * 1989-11-13 1993-02-23 Nova Pharmaceutical Corporation Lipsopheres for controlled delivery of substances
AU658608B2 (en) * 1991-03-25 1995-04-27 Astellas Pharma Europe B.V. Topical preparation containing a suspension of solid lipid particles
WO1992018147A1 (en) * 1991-04-19 1992-10-29 Affinity Biotech, Inc. Convertible microemulsion formulations
NZ243721A (en) * 1991-07-26 1994-11-25 Smithkline Beecham Corp Self-emulsifying microemulsion comprising water soluble drug, high hlb surfactant and a lipophilic phase containing fatty acid triglyceride and a low hlb surfactant
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles

Also Published As

Publication number Publication date
EP0773780A1 (en) 1997-05-21
AU706516B2 (en) 1999-06-17
ATE217186T1 (de) 2002-05-15
DE69526655T2 (de) 2002-12-05
EP0773780B1 (en) 2002-05-08
CA2193497C (en) 2000-10-17
US5672358A (en) 1997-09-30
AU2907095A (en) 1996-01-15
ZA955153B (en) 1996-05-07
JP2002510279A (ja) 2002-04-02
DE69526655D1 (de) 2002-06-13
DK0773780T3 (da) 2002-09-09
JP3583435B2 (ja) 2004-11-04
CA2193497A1 (en) 1995-12-28
EP0773780A4 (en) 1998-09-30
WO1995035096A1 (en) 1995-12-28

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