ATE217525T1 - Tiagabin enthaltende spheroide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel - Google Patents

Tiagabin enthaltende spheroide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Info

Publication number
ATE217525T1
ATE217525T1 AT98954682T AT98954682T ATE217525T1 AT E217525 T1 ATE217525 T1 AT E217525T1 AT 98954682 T AT98954682 T AT 98954682T AT 98954682 T AT98954682 T AT 98954682T AT E217525 T1 ATE217525 T1 AT E217525T1
Authority
AT
Austria
Prior art keywords
spheroids
tiagabine
production
medicinal products
same
Prior art date
Application number
AT98954682T
Other languages
English (en)
Inventor
Patrice Debregeas
Gerard Leduc
Pascal Oury
Pascal Suplie
Original Assignee
Ethypharm Lab Prod Ethiques
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm Lab Prod Ethiques filed Critical Ethypharm Lab Prod Ethiques
Application granted granted Critical
Publication of ATE217525T1 publication Critical patent/ATE217525T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98954682T 1997-11-21 1998-11-19 Tiagabin enthaltende spheroide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel ATE217525T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9714635A FR2771292B1 (fr) 1997-11-21 1997-11-21 Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques
PCT/IB1998/001910 WO1999026626A1 (en) 1997-11-21 1998-11-19 Spheroids containing tiagabine, preparation process and pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ATE217525T1 true ATE217525T1 (de) 2002-06-15

Family

ID=9513639

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98954682T ATE217525T1 (de) 1997-11-21 1998-11-19 Tiagabin enthaltende spheroide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Country Status (12)

Country Link
US (1) US6139877A (de)
EP (1) EP1032391B1 (de)
JP (1) JP2001523719A (de)
AT (1) ATE217525T1 (de)
AU (1) AU1170399A (de)
DE (1) DE69805433T2 (de)
DK (1) DK1032391T3 (de)
ES (1) ES2173638T3 (de)
FR (1) FR2771292B1 (de)
PT (1) PT1032391E (de)
WO (1) WO1999026626A1 (de)
ZA (1) ZA9810630B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
FR2771291B1 (fr) * 1997-11-21 2000-02-25 Ethypharm Lab Prod Ethiques Spheroides, procede de preparation et compositions pharmaceutiques
BR0009557A (pt) 1999-04-06 2002-05-28 Ethypharm Lab Prod Ethiques Suspensão farmacêutica para beber de ibuprofeno
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
FR2845289B1 (fr) * 2002-10-04 2004-12-03 Ethypharm Sa Spheroides, procede de preparation et compositions pharmaceutiques.
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
ES2221804B1 (es) * 2003-06-18 2006-04-01 Lipofoods, S.L. Microcapsulas para la administracion de ingredientes activos.
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
SG10201407965XA (en) 2009-12-02 2015-02-27 Aptalis Pharma Ltd Fexofenadine microcapsules and compositions containing them
US20110212171A1 (en) * 2010-01-08 2011-09-01 Eurand, Inc. Taste masked topiramate composition and an orally disintegrating tablet comprising the same
RU2590979C2 (ru) 2011-02-11 2016-07-10 ЗедЭкс ФАРМА, ЭлЭлСи Составы l-ментола, состоящие из множества частиц, и связанные с ними способы
US8911780B2 (en) 2011-02-11 2014-12-16 Zx Pharma, Llc Multiparticulate L-menthol formulations and related methods
US8808736B2 (en) 2011-02-11 2014-08-19 Zx Pharma, Llc Enteric coated multiparticulate controlled release peppermint oil composition and related methods
RS58325B1 (sr) 2013-04-23 2019-03-29 Zx Pharma Llc Enterosolventno obloženi višečestični preparat sa proteinskom sub-oblogom

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
JPS62153213A (ja) * 1985-12-26 1987-07-08 Dai Ichi Seiyaku Co Ltd 腸溶性粒状物
CA1338596C (en) * 1988-09-27 1996-09-17 Hiroyoshi Koyama Granules having core and their production
JP2572673B2 (ja) * 1990-07-25 1997-01-16 エスエス製薬株式会社 徐放性錠剤
DK58291D0 (da) * 1991-04-02 1991-04-02 Novo Nordisk As Krystalinsk stof og dets fremstilling
ZA923474B (en) * 1991-05-20 1993-01-27 Marion Merrell Dow Inc Diltiazem formulation
US5326570A (en) * 1991-07-23 1994-07-05 Pharmavene, Inc. Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine
WO1995005808A1 (en) * 1993-08-24 1995-03-02 Abbott Laboratories Oil-based tableting method
US5430021A (en) * 1994-03-18 1995-07-04 Pharmavene, Inc. Hydrophobic drug delivery systems
US5484608A (en) * 1994-03-28 1996-01-16 Pharmavene, Inc. Sustained-release drug delivery system
US5447729A (en) * 1994-04-07 1995-09-05 Pharmavene, Inc. Multilamellar drug delivery systems
ZA953078B (en) * 1994-04-28 1996-01-05 Alza Corp Effective therapy for epilepsies
US5750140A (en) * 1994-05-20 1998-05-12 Novo Nordisk A/S Transdermal delivery of tiagabine
EP0830132B1 (de) * 1995-05-05 2002-01-16 Novo Nordisk A/S Tiagabinhydrochlorid enthaltendes arzneimittel und verfahren zu dessen herstellung
US5914333A (en) * 1996-07-31 1999-06-22 Novo Nordisk A/S Treatment of psychotic disorders
CZ301382B6 (cs) * 1997-03-12 2010-02-10 Abbott Laboratories Chad377/Ap6D-2 Hydrofilní binární systémy pro podávání cyklosporinu

Also Published As

Publication number Publication date
DE69805433T2 (de) 2002-11-07
FR2771292B1 (fr) 2000-02-18
FR2771292A1 (fr) 1999-05-28
ZA9810630B (en) 1999-05-24
DE69805433D1 (de) 2002-06-20
AU1170399A (en) 1999-06-15
WO1999026626A1 (en) 1999-06-03
ES2173638T3 (es) 2002-10-16
EP1032391A1 (de) 2000-09-06
JP2001523719A (ja) 2001-11-27
EP1032391B1 (de) 2002-05-15
DK1032391T3 (da) 2002-09-09
US6139877A (en) 2000-10-31
PT1032391E (pt) 2002-09-30

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