ATE218060T1 - Zusammenstellungen die beta-amyloid protein bedingte zytotoxizität verhindern - Google Patents

Zusammenstellungen die beta-amyloid protein bedingte zytotoxizität verhindern

Info

Publication number
ATE218060T1
ATE218060T1 AT97930746T AT97930746T ATE218060T1 AT E218060 T1 ATE218060 T1 AT E218060T1 AT 97930746 T AT97930746 T AT 97930746T AT 97930746 T AT97930746 T AT 97930746T AT E218060 T1 ATE218060 T1 AT E218060T1
Authority
AT
Austria
Prior art keywords
amyloid protein
compositions
optionally substituted
protein related
prevent beta
Prior art date
Application number
AT97930746T
Other languages
English (en)
Inventor
Masaomi Miyamoto
Keisuke Hirai
Giichi Goto
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE218060T1 publication Critical patent/ATE218060T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT97930746T 1996-07-11 1997-07-10 Zusammenstellungen die beta-amyloid protein bedingte zytotoxizität verhindern ATE218060T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18209596 1996-07-11
PCT/JP1997/002391 WO1998002149A2 (en) 1996-07-11 1997-07-10 Use of idebenone and analogues against beta amyloid induced cytotoxicity

Publications (1)

Publication Number Publication Date
ATE218060T1 true ATE218060T1 (de) 2002-06-15

Family

ID=16112269

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97930746T ATE218060T1 (de) 1996-07-11 1997-07-10 Zusammenstellungen die beta-amyloid protein bedingte zytotoxizität verhindern

Country Status (7)

Country Link
US (1) US6271266B1 (de)
EP (1) EP0915696B1 (de)
AT (1) ATE218060T1 (de)
AU (1) AU3458997A (de)
CA (1) CA2252519A1 (de)
DE (1) DE69712888D1 (de)
WO (1) WO1998002149A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2471530T (pt) * 2005-06-01 2017-04-19 Edison Pharmaceuticals Inc Produtos terapêuticos com atividade redox para o tratamento de doenças mitocondriais e de outras condições e modulação de biomarcadores energéticos
JP2009508867A (ja) * 2005-09-15 2009-03-05 エジソン ファーマシューティカルズ， インコーポレイテッド ミトコンドリア病および関連した様態の治療ならびにエネルギーバイオマーカーの調節のための酸化還元活性治療剤のテイル改変体
EP1986636B1 (de) 2006-02-22 2013-04-24 Edison Pharmaceuticals, Inc. Phenol- und 1,4-benzochinon-derivate zur verwendung in der behandlung von erkrankungen der mitochondrien
EP1891946A1 (de) * 2006-08-14 2008-02-27 Santhera Pharmaceuticals (Schweiz) AG Transmukosale Verabreichung von 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinon
EP3456707B1 (de) 2007-11-06 2020-04-15 PTC Therapeutics, Inc. 4-(p-quinonyl)-2-hydroxybutanamid-derivate zur behandlung von mitochondrialen erkrankungen
US8314153B2 (en) 2008-09-10 2012-11-20 Edison Pharmaceuticals, Inc. Treatment of pervasive developmental disorders with redox-active therapeutics
US8263094B2 (en) * 2008-09-23 2012-09-11 Eastman Chemical Company Esters of 4,5-disubstituted-oxy-2-methyl-3,6-dioxo-cyclohexa-1,4-dienyl alkyl acids and preparation thereof
RS55173B1 (sr) * 2010-08-16 2017-01-31 Santhera Pharmaceuticals (Schweiz) Ag Uređaj i sistem za proizvodnju aerosola sa poboljšanim protokom vazduha
WO2014035356A1 (en) * 2012-08-31 2014-03-06 Mahmut Bilgic Tablet formulations comprising a quinone derivative active agent
BR112017012988B1 (pt) 2014-12-16 2023-10-03 Ptc Therapeutics, Inc Formas polimoráficas e amorfas de (r)-2-hidroxi-2- metil-4- (2,4,5-trimetil-3,6-dioxociclohexa-1,4-dienil) butanamida
WO2017106803A1 (en) 2015-12-17 2017-06-22 Bioelectron Technology Corporation Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
EP3615502B1 (de) 2017-04-21 2023-06-21 University Of Tasmania Therapeutische verbindungen und verfahren
MX2021004329A (es) 2018-10-17 2021-06-08 Ptc Therapeutics Inc 2,3,5-trimetil-6-nonilciclohexa-2,5-dien-1,4-diona para suprimir y tratar alfa-sinucleinopatias, tauopatias y otros trastornos.
MX2024000445A (es) 2021-07-08 2024-04-05 Ptc Therapeutics Inc Composiciones farmaceuticas que comprenden 2,3,5-trimetil-6-nonilc iclohexa-2,5-dieno-1,4-diona.
CN119792259A (zh) * 2024-10-14 2025-04-11 中国农业大学 艾地苯醌在制备朊病毒病药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08768B2 (ja) 1989-08-24 1996-01-10 武田薬品工業株式会社 神経成長因子分泌誘導剤
JP2849286B2 (ja) * 1992-07-09 1999-01-20 三菱電機株式会社 半導体装置の製造方法
EP0629400B1 (de) 1993-06-18 1999-09-22 Takeda Chemical Industries, Ltd. Idebenone-haltige Zusammensetzungen zur Behandlung von M. Alzheimer

Also Published As

Publication number Publication date
EP0915696A2 (de) 1999-05-19
US6271266B1 (en) 2001-08-07
DE69712888D1 (de) 2002-07-04
CA2252519A1 (en) 1998-01-22
WO1998002149A3 (en) 1998-06-04
EP0915696B1 (de) 2002-05-29
AU3458997A (en) 1998-02-09
WO1998002149A2 (en) 1998-01-22

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