ATE218127T1 - Verfahren zur sulfinylierung von heterocyclischen verbindungen - Google Patents
Verfahren zur sulfinylierung von heterocyclischen verbindungenInfo
- Publication number
- ATE218127T1 ATE218127T1 AT95102219T AT95102219T ATE218127T1 AT E218127 T1 ATE218127 T1 AT E218127T1 AT 95102219 T AT95102219 T AT 95102219T AT 95102219 T AT95102219 T AT 95102219T AT E218127 T1 ATE218127 T1 AT E218127T1
- Authority
- AT
- Austria
- Prior art keywords
- het
- halo
- substd
- opt
- alkyl
- Prior art date
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 3
- 125000001188 haloalkyl group Chemical group 0.000 abstract 3
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 3
- PAPNRQCYSFBWDI-UHFFFAOYSA-N 2,5-Dimethyl-1H-pyrrole Chemical group CC1=CC=C(C)N1 PAPNRQCYSFBWDI-UHFFFAOYSA-N 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- HCMJWOGOISXSDL-UHFFFAOYSA-N (2-isothiocyanato-1-phenylethyl)benzene Chemical compound C=1C=CC=CC=1C(CN=C=S)C1=CC=CC=C1 HCMJWOGOISXSDL-UHFFFAOYSA-N 0.000 abstract 1
- ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical compound C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 abstract 1
- WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical compound C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 abstract 1
- FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical compound C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- ZLTPDFXIESTBQG-UHFFFAOYSA-N isothiazole Chemical compound C=1C=NSC=1 ZLTPDFXIESTBQG-UHFFFAOYSA-N 0.000 abstract 1
- CTAPFRYPJLPFDF-UHFFFAOYSA-N isoxazole Chemical compound C=1C=NOC=1 CTAPFRYPJLPFDF-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000000168 pyrrolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000003852 triazoles Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Coloring (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9402222A FR2716453B1 (fr) | 1994-02-22 | 1994-02-22 | Procédé de sulfinylation de composés hétérocycliques. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE218127T1 true ATE218127T1 (de) | 2002-06-15 |
Family
ID=9460460
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95102219T ATE218127T1 (de) | 1994-02-22 | 1995-02-17 | Verfahren zur sulfinylierung von heterocyclischen verbindungen |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5618945A (de) |
| EP (1) | EP0668269B1 (de) |
| JP (3) | JP3963965B2 (de) |
| KR (1) | KR100370990B1 (de) |
| CN (1) | CN1056833C (de) |
| AT (1) | ATE218127T1 (de) |
| AU (1) | AU678876B2 (de) |
| BR (1) | BR9500858A (de) |
| CA (1) | CA2143135C (de) |
| CZ (1) | CZ294640B6 (de) |
| DE (1) | DE69526815T2 (de) |
| DK (1) | DK0668269T3 (de) |
| ES (1) | ES2173932T3 (de) |
| FI (1) | FI113764B (de) |
| FR (1) | FR2716453B1 (de) |
| HU (1) | HU214283B (de) |
| IL (1) | IL112708A (de) |
| PL (1) | PL183151B1 (de) |
| PT (1) | PT668269E (de) |
| RO (1) | RO113639B1 (de) |
| RU (1) | RU2136665C1 (de) |
| SK (1) | SK282510B6 (de) |
| UA (1) | UA44226C2 (de) |
| ZA (1) | ZA951468B (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0976737B1 (de) * | 1997-04-07 | 2009-06-10 | Nihon Nohyaku Co., Ltd. | Pyrazolderivate, verfahren zu ihrer herstellung, zwischenprodukte und schädlingsbekämpfungsmittel, das diese als aktiven bestandteil enthält |
| FR2784101B1 (fr) * | 1998-09-14 | 2000-11-17 | Rhodia Chimie Sa | Procede de condensation de derive(s) aromatique(s) et d'un derive sulfinique dont la chaine carbonee est attachee a la fonction sulfinique par un atome de carbone perhalogene |
| GB9907458D0 (en) * | 1999-03-31 | 1999-05-26 | Rhone Poulenc Agrochimie | Processes for preparing pesticidal intermediates |
| AU763625B2 (en) | 1999-06-29 | 2003-07-31 | Nihon Nohyaku Co., Ltd. | Pyrazole derivatives and process for producing the same, and pesticides containing the same as the active ingredient |
| PL206482B1 (pl) | 1999-10-22 | 2010-08-31 | Basf Agro B V Arnhem Nl | Sposób wytwarzania pochodnych 4-trifluorometylosulfinylopirazolu |
| EP1331222A1 (de) * | 2002-01-28 | 2003-07-30 | Virbac S.A. | Umweltfreundliche Reagenzien und Verfahren zur Halogenalkylsulfinylierung von organischen Verbindungen |
| KR20060006949A (ko) * | 2003-04-29 | 2006-01-20 | 아크조 노벨 엔.브이. | 반용매 고화 방법 |
| CA2560510C (en) * | 2004-03-18 | 2009-10-13 | Pfizer Inc. | N-(1-arylpyrazol-4yl) sulfonamides and their use as parasiticides |
| CA2630849C (en) | 2005-12-14 | 2013-05-14 | Makhteshim Chemical Works Ltd. | Polymorphs and amorphous forms of 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1h-pyrazole-3-carbonitrile |
| CN101168529B (zh) * | 2006-10-24 | 2011-03-23 | 温州大学 | 氟虫腈、乙虫腈及其衍生物的合成方法 |
| PL2081908T3 (pl) * | 2006-11-10 | 2013-09-30 | Basf Agro B V Arnhem Nl Zuerich Branch | Sposób sulfinylowania pochodnej pirazolu |
| ES2422297T3 (es) * | 2006-11-10 | 2013-09-10 | Basf Se | Proceso para la sulfinilación de un derivado de pirazol |
| AU2007316720B2 (en) * | 2006-11-10 | 2013-05-09 | Basf Se | Process for the sulfinylation of a pyrazole derivative |
| EP2083628A1 (de) | 2006-11-10 | 2009-08-05 | Basf Se | Kristalline fipronil-modifikation |
| UA110598C2 (uk) | 2006-11-10 | 2016-01-25 | Басф Се | Спосіб одержання кристалічної модифікації фіпронілу |
| HRP20110641T4 (hr) | 2006-11-10 | 2015-05-22 | Basf Se | Kristalna modifikacija fipronila |
| AU2007316639B2 (en) | 2006-11-10 | 2012-12-20 | Basf Se | Crystalline modification of fipronil |
| US7378547B1 (en) | 2006-11-28 | 2008-05-27 | E.I. Du Pont De Nemours And Company | Process for the synthesis of hydroxy aromatic acids |
| FR2925493B1 (fr) * | 2007-12-19 | 2011-09-30 | Vetoquinol | Procede de preparation du fipronil et d'analogues de celui-ci. |
| DK2349987T3 (da) * | 2008-10-02 | 2013-03-11 | Basf Se | Fremgangsmåde til fremstilling og oprensning af trifluormethansulfinsyre |
| WO2012095871A2 (en) | 2011-01-14 | 2012-07-19 | Keki Hormusji Gharda | Polymorphism in 5-amino- 1 -(2,6-dichloro-4- trifluoromethylphenyl)-3-cyano-4-trifluoro methyl sulfinyl pyrazole |
| CN102093295A (zh) * | 2011-03-10 | 2011-06-15 | 江苏长青农化股份有限公司 | 一种农药杀虫剂氟虫腈的合成方法 |
| TWI579274B (zh) | 2012-04-20 | 2017-04-21 | 龍馬躍公司 | 製備1-芳基-5-烷基吡唑化合物的改良方法 |
| US8993613B2 (en) | 2013-04-17 | 2015-03-31 | The Hartz Mountain Corporation | Ectoparasiticidal formulations |
| CN104557713B (zh) * | 2013-10-22 | 2018-08-21 | 江苏托球农化股份有限公司 | 高纯度氟虫腈制备方法 |
| EP3412659A1 (de) * | 2017-06-09 | 2018-12-12 | Solvay Sa | Verfahren zur herstellung von schwefel-substituierte pyrazolederivate |
| CN107963993A (zh) * | 2018-01-06 | 2018-04-27 | 江苏托球农化股份有限公司 | 一种高纯度氟虫腈的制备方法 |
| EP3941907A4 (de) * | 2019-03-19 | 2023-01-04 | Gharda Chemicals Limited | Verfahren zur synthese von fipronil |
| CN113149873A (zh) * | 2021-03-10 | 2021-07-23 | 浙江埃森化学有限公司 | 一种三氟甲基亚磺酰氯的制备方法 |
| CN115650919A (zh) * | 2022-04-13 | 2023-01-31 | 华东理工大学 | 一种自三氯甲基亚磺酰氯制备氟虫腈的方法 |
| CN115353490A (zh) * | 2022-09-26 | 2022-11-18 | 安徽美诺华药物化学有限公司 | 一种氟虫腈的纯化工艺 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5187185A (en) * | 1988-12-09 | 1993-02-16 | Rhone-Poulenc Ag Company | Pesticidal 1-arylpyrroles |
| JPS55157570A (en) * | 1979-05-26 | 1980-12-08 | Nissan Chem Ind Ltd | Sulfamylimidazole derivative, and agricultural and horticultural fungicide |
| MA19539A1 (fr) * | 1981-07-17 | 1983-04-01 | May & Baker Ltd | N Acylaminophenylpyrazoles |
| US5232940A (en) * | 1985-12-20 | 1993-08-03 | Hatton Leslie R | Derivatives of N-phenylpyrazoles |
| GB8713768D0 (en) * | 1987-06-12 | 1987-07-15 | May & Baker Ltd | Compositions of matter |
| DE3719732A1 (de) * | 1987-06-12 | 1989-01-05 | Bayer Ag | Substituierte 5-methylamino-1-arylpyrazole |
| DE3719733A1 (de) * | 1987-06-12 | 1989-01-05 | Bayer Ag | Substituierte 5-ethylamino-1-arylpyrazole |
| DE3724919A1 (de) * | 1987-07-28 | 1989-02-09 | Bayer Ag | 1-arylpyrazole |
| DE3820190A1 (de) * | 1988-06-14 | 1989-12-21 | Cassella Ag | Pyrrolderivate, ihre herstellung und ihre verwendung als pharmazeutische wirkstoffe |
| CA2004776C (fr) * | 1988-12-13 | 2000-04-25 | Claude Wakselman | Procede de preparation de perfluoroalkylthioethers |
| US5223525A (en) * | 1989-05-05 | 1993-06-29 | Rhone-Poulenc Ag Company | Pesticidal 1-arylimidazoles |
| GB9120641D0 (en) * | 1991-09-27 | 1991-11-06 | Ici Plc | Heterocyclic compounds |
-
1994
- 1994-02-22 FR FR9402222A patent/FR2716453B1/fr not_active Expired - Lifetime
-
1995
- 1995-02-16 UA UA95028159A patent/UA44226C2/uk unknown
- 1995-02-17 ES ES95102219T patent/ES2173932T3/es not_active Expired - Lifetime
- 1995-02-17 DE DE69526815T patent/DE69526815T2/de not_active Expired - Lifetime
- 1995-02-17 EP EP95102219A patent/EP0668269B1/de not_active Expired - Lifetime
- 1995-02-17 DK DK95102219T patent/DK0668269T3/da active
- 1995-02-17 PT PT95102219T patent/PT668269E/pt unknown
- 1995-02-17 AT AT95102219T patent/ATE218127T1/de active
- 1995-02-20 SK SK234-95A patent/SK282510B6/sk not_active IP Right Cessation
- 1995-02-20 IL IL11270895A patent/IL112708A/xx not_active IP Right Cessation
- 1995-02-21 RU RU95102481A patent/RU2136665C1/ru active
- 1995-02-21 HU HU9500522A patent/HU214283B/hu unknown
- 1995-02-21 CZ CZ1995461A patent/CZ294640B6/cs not_active IP Right Cessation
- 1995-02-21 BR BR9500858A patent/BR9500858A/pt active IP Right Grant
- 1995-02-21 FI FI950800A patent/FI113764B/fi not_active IP Right Cessation
- 1995-02-21 PL PL95307393A patent/PL183151B1/pl unknown
- 1995-02-22 CN CN95100789A patent/CN1056833C/zh not_active Expired - Lifetime
- 1995-02-22 JP JP03385695A patent/JP3963965B2/ja not_active Expired - Lifetime
- 1995-02-22 RO RO95-00361A patent/RO113639B1/ro unknown
- 1995-02-22 CA CA002143135A patent/CA2143135C/fr not_active Expired - Lifetime
- 1995-02-22 KR KR1019950003467A patent/KR100370990B1/ko not_active Expired - Lifetime
- 1995-02-22 AU AU12383/95A patent/AU678876B2/en not_active Expired
- 1995-02-22 US US08/392,243 patent/US5618945A/en not_active Expired - Lifetime
- 1995-02-22 ZA ZA951468A patent/ZA951468B/xx unknown
-
2005
- 2005-01-26 JP JP2005017759A patent/JP4447478B2/ja not_active Expired - Lifetime
-
2007
- 2007-02-07 JP JP2007027926A patent/JP4731503B2/ja not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEIH | Change in the person of patent owner |