ATE218354T1 - Sauerstoff reduzierte wässerige faktor viii- enthaltene lösung - Google Patents

Sauerstoff reduzierte wässerige faktor viii- enthaltene lösung

Info

Publication number
ATE218354T1
ATE218354T1 AT94915307T AT94915307T ATE218354T1 AT E218354 T1 ATE218354 T1 AT E218354T1 AT 94915307 T AT94915307 T AT 94915307T AT 94915307 T AT94915307 T AT 94915307T AT E218354 T1 ATE218354 T1 AT E218354T1
Authority
AT
Austria
Prior art keywords
factor viii
pct
aqueous solution
present
solution containing
Prior art date
Application number
AT94915307T
Other languages
English (en)
Inventor
Thomas Oesterberg
Angelica Fatouros
Original Assignee
Biovitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovitrum Ab filed Critical Biovitrum Ab
Application granted granted Critical
Publication of ATE218354T1 publication Critical patent/ATE218354T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
AT94915307T 1993-05-07 1994-03-24 Sauerstoff reduzierte wässerige faktor viii- enthaltene lösung ATE218354T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE19939301581A SE9301581D0 (sv) 1993-05-07 1993-05-07 Protein formulation
PCT/SE1994/000265 WO1994026286A1 (en) 1993-05-07 1994-03-24 Oxygen-reduced aqueous solution of factor viii

Publications (1)

Publication Number Publication Date
ATE218354T1 true ATE218354T1 (de) 2002-06-15

Family

ID=20389868

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94915307T ATE218354T1 (de) 1993-05-07 1994-03-24 Sauerstoff reduzierte wässerige faktor viii- enthaltene lösung

Country Status (24)

Country Link
US (1) US5962650A (de)
EP (1) EP0700299B1 (de)
JP (1) JP3751633B2 (de)
KR (1) KR100304143B1 (de)
CN (1) CN1113655C (de)
AT (1) ATE218354T1 (de)
AU (1) AU681883B2 (de)
CA (1) CA2161350C (de)
CZ (1) CZ293527B6 (de)
DE (1) DE69430745T2 (de)
DK (1) DK0700299T3 (de)
EE (1) EE03118B1 (de)
ES (1) ES2177579T3 (de)
FI (1) FI111910B (de)
HU (1) HU215263B (de)
NO (1) NO321769B1 (de)
NZ (1) NZ266031A (de)
PL (1) PL174866B1 (de)
PT (1) PT700299E (de)
RU (1) RU2142290C1 (de)
SE (1) SE9301581D0 (de)
SK (1) SK283002B6 (de)
WO (1) WO1994026286A1 (de)
ZA (1) ZA942251B (de)

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SE9403915D0 (sv) * 1994-11-14 1994-11-14 Annelie Almstedt Process A
SE9501189D0 (sv) * 1995-03-31 1995-03-31 Pharmacia Ab Protein formulation
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US5763401A (en) * 1996-07-12 1998-06-09 Bayer Corporation Stabilized albumin-free recombinant factor VIII preparation having a low sugar content
PT2193809E (pt) * 1999-02-22 2015-08-24 Baxter Int Formulações de fator viii livres de albumina
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JP3466516B2 (ja) 1999-09-07 2003-11-10 科学技術振興事業団 安定保存可能な酸素輸液剤
JP2005530682A (ja) * 2001-12-21 2005-10-13 ノボ　ノルディスク　アクティーゼルスカブ 修飾第ｖｉｉ因子ポリペプチドの液体組成物
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US20040009918A1 (en) * 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
CA2490342C (en) * 2002-06-21 2015-06-16 Novo Nordisk A/S Stabilised solid compositions of factor vii polypeptides
US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
BRPI0409936A (pt) * 2003-05-23 2006-04-25 Novo Nordisk Healthcare Ag uso de um material, recipiente pelo menos parcialmente cheio, e, kit médico
ATE547114T1 (de) * 2003-06-25 2012-03-15 Novo Nordisk Healthcare Ag Flüssige zusammensetzungen von factor vii polypeptiden
DE602004023848D1 (de) * 2003-07-01 2009-12-10 Novo Nordisk Healthcare Ag Von factor vii polypeptiden
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ES2676644T3 (es) * 2003-12-19 2018-07-23 Novo Nordisk Health Care Ag Composiciones estabilizadas de polipéptidos de factor VII
JP2007536230A (ja) * 2004-05-03 2007-12-13 エモリー ユニバーシティ ブタＢドメイン欠損ｆＶＩＩＩの投与方法
US7504377B2 (en) 2006-10-23 2009-03-17 Ikor, Inc. Nitric oxide-blocked cross-linked tetrameric hemoglobin
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ES2364118T3 (es) * 2007-07-11 2011-08-25 Novo Nordisk A/S Purificación de factor viii usando una resina de modo mixto o multimodal.
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MX2011001624A (es) 2008-08-21 2011-03-28 Octapharma Ag Factor viii y ix humano producido en forma recombinante.
ATE551050T1 (de) * 2008-09-03 2012-04-15 Octapharma Ag Stabilisierte zusammensetzungen für rekombinant hergestellten faktor viii
BRPI0921429B1 (pt) 2008-11-07 2022-07-12 Takeda Pharmaceutical Company Limited Formulação farmacêutica liofilizada estável, e, método para preparar um fator liofilizado estável
US10172949B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
ES2966234T3 (es) 2009-06-09 2024-04-18 Prolong Pharmaceuticals Llc Composiciones de hemoglobina
US10172950B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
GB0915480D0 (en) * 2009-09-04 2009-10-07 Arecor Ltd Stable formulation of factor viii
US12089589B2 (en) 2009-10-12 2024-09-17 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
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CA2816575C (en) 2010-11-05 2019-06-11 Baxter Healthcare S.A. A new variant of antihemophilic factor viii having increased specific activity
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US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
EP3061509B1 (de) 2011-08-10 2019-05-22 New Health Sciences, Inc. Integrierte filtervorrichtung zum trennen von plasma und leukozyten und zum abreichern von sauerstoff- und/oder c02
CA2902061C (en) 2013-02-28 2023-08-08 New Health Sciences, Inc. Gas depletion and gas addition devices for blood treatment
ES2524516B1 (es) * 2014-05-29 2015-03-31 Grifols Worldwide Operations Limited Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido
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EP4623991A3 (de) 2015-05-18 2025-12-17 Hemanext Inc. Verfahren zur lagerung von vollblut und zusammensetzungen daraus
EP3463466B1 (de) 2016-05-27 2022-02-16 Hemanext Inc. Anaerobe blutlagerung und verfahren zur inaktivierung von pathogenen
EP3833382A1 (de) 2018-08-07 2021-06-16 GlaxoSmithKline Biologicals S.A. Verfahren und impfstoffe

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Also Published As

Publication number Publication date
NZ266031A (en) 1997-04-24
KR960702317A (ko) 1996-04-27
DE69430745D1 (de) 2002-07-11
CZ286995A3 (en) 1996-05-15
FI955305L (fi) 1995-11-06
PT700299E (pt) 2002-11-29
NO954457L (no) 1995-11-07
SE9301581D0 (sv) 1993-05-07
ZA942251B (en) 1994-11-01
KR100304143B1 (ko) 2001-11-22
US5962650A (en) 1999-10-05
SK138395A3 (en) 1997-02-05
WO1994026286A1 (en) 1994-11-24
EE03118B1 (et) 1998-10-15
EP0700299A1 (de) 1996-03-13
DK0700299T3 (da) 2002-09-23
CN1122573A (zh) 1996-05-15
JP3751633B2 (ja) 2006-03-01
AU6659794A (en) 1994-12-12
CA2161350C (en) 2007-10-30
FI111910B (fi) 2003-10-15
NO321769B1 (no) 2006-07-03
PL311567A1 (en) 1996-02-19
CZ293527B6 (cs) 2004-05-12
JPH08509745A (ja) 1996-10-15
FI955305A0 (fi) 1995-11-06
HU215263B (hu) 1998-11-30
CN1113655C (zh) 2003-07-09
DE69430745T2 (de) 2002-10-17
SK283002B6 (sk) 2003-01-09
HUT73693A (en) 1996-09-30
EP0700299B1 (de) 2002-06-05
NO954457D0 (no) 1995-11-07
HU9503171D0 (en) 1996-01-29
PL174866B1 (pl) 1998-09-30
RU2142290C1 (ru) 1999-12-10
AU681883B2 (en) 1997-09-11
CA2161350A1 (en) 1994-11-24
ES2177579T3 (es) 2002-12-16

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UEP Publication of translation of european patent specification