ATE218361T1 - Löslicher ldl-rezeptor, seine herstellung und verwendung - Google Patents

Löslicher ldl-rezeptor, seine herstellung und verwendung

Info

Publication number
ATE218361T1
ATE218361T1 AT93100587T AT93100587T ATE218361T1 AT E218361 T1 ATE218361 T1 AT E218361T1 AT 93100587 T AT93100587 T AT 93100587T AT 93100587 T AT93100587 T AT 93100587T AT E218361 T1 ATE218361 T1 AT E218361T1
Authority
AT
Austria
Prior art keywords
ldl receptor
production
soluble ldl
soluble
receptor protein
Prior art date
Application number
AT93100587T
Other languages
English (en)
Inventor
Menachem Rubinstein
Daniela Novick
Nathan Tal
Dina G Fischer
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL100696A external-priority patent/IL100696A0/xx
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Application granted granted Critical
Publication of ATE218361T1 publication Critical patent/ATE218361T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Sewing Machines And Sewing (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
AT93100587T 1992-01-19 1993-01-15 Löslicher ldl-rezeptor, seine herstellung und verwendung ATE218361T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL100696A IL100696A0 (en) 1992-01-19 1992-01-19 Antiviral protein and its preparation
IL10291592A IL102915A (en) 1992-01-19 1992-08-23 Soluble ldl receptor and its preparation

Publications (1)

Publication Number Publication Date
ATE218361T1 true ATE218361T1 (de) 2002-06-15

Family

ID=26322379

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93100587T ATE218361T1 (de) 1992-01-19 1993-01-15 Löslicher ldl-rezeptor, seine herstellung und verwendung

Country Status (10)

Country Link
EP (1) EP0553667B1 (de)
JP (2) JP3784078B2 (de)
AT (1) ATE218361T1 (de)
AU (1) AU663751B2 (de)
CA (1) CA2087494C (de)
DE (1) DE69331977T2 (de)
DK (1) DK0553667T3 (de)
ES (1) ES2177531T3 (de)
IL (1) IL102915A (de)
PT (1) PT553667E (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999038524A2 (en) * 1998-01-29 1999-08-05 Patrick Thomas Prendergast Therapeutic administration of low density lipoprotein receptor for viral infections and immune regulation
MX367012B (es) 2007-06-01 2019-08-02 Univ Maryland Agentes de union al receptor de la region constante fc de inmunoglobulina.
IL188628A0 (en) * 2008-01-07 2008-12-29 Yeda Res & Dev Use of soluble ldl-r for viral hepatitis
AU2011282579B2 (en) 2010-07-28 2014-10-23 Gliknik Inc. Fusion proteins of natural human protein fragments to create orderly multimerized immunoglobulin Fc compositions
HK1203528A1 (zh) * 2012-01-27 2015-10-30 Gliknik Inc. 包含igg2鉸鏈結構域的融合蛋白
FI3325011T6 (fi) 2015-07-24 2023-05-11 Ihmisen proteiinifragmenttien fuusioproteiineja järjestyksenmukaisesti multimerisoitujen, paremmin komplementtia sitovien immunoglobuliini-fc-koostumusten muodostamiseksi
US11034775B2 (en) 2016-06-07 2021-06-15 Gliknik Inc. Cysteine-optimized stradomers
KR102729723B1 (ko) 2016-12-09 2024-11-15 글리크닉 인코포레이티드 다합체화 스트라도머인 gl-2045의 제조 최적화
JP7519774B2 (ja) 2016-12-09 2024-07-22 グリックニック インコーポレイテッド 多価fc化合物を用いる炎症性疾患の治療方法
CA3266482A1 (en) * 2022-09-15 2024-03-21 Yeda Research And Development Co. Ltd. Virotherapy Compositions and Methods
CN120548322A (zh) * 2022-12-08 2025-08-26 美国杰特贝林生物制品有限公司 可解离的包膜结合蛋白及其用途
EP4688822A1 (de) * 2023-05-23 2026-02-11 JLP Health GmbH Von ldlr abgeleitete polypeptide für antivirale anwendungen
EP4467563A1 (de) * 2023-05-23 2024-11-27 JLP Health GmbH Von ldlr abgeleitete polypeptide für antivirale anwendungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4614651A (en) * 1981-07-12 1986-09-30 Damon Biotech, Inc. Interferon epsilon
US4454115A (en) * 1981-10-23 1984-06-12 Wisconsin Alumni Research Foundation Method of reducing the level of low density lipoproteins in the serum of a patient
CA2055122A1 (en) * 1990-11-13 1992-05-14 Robert I. Grove Methods for stimulating ldl uptake and ldl receptor expression

Also Published As

Publication number Publication date
DE69331977D1 (de) 2002-07-11
JPH06220099A (ja) 1994-08-09
JP2006136341A (ja) 2006-06-01
AU663751B2 (en) 1995-10-19
DE69331977T2 (de) 2002-09-19
PT553667E (pt) 2002-10-31
JP3784078B2 (ja) 2006-06-07
CA2087494A1 (en) 1993-07-20
IL102915A0 (en) 1993-01-31
EP0553667B1 (de) 2002-06-05
ES2177531T3 (es) 2002-12-16
DK0553667T3 (da) 2002-09-16
CA2087494C (en) 2008-10-07
IL102915A (en) 2005-12-18
AU3188993A (en) 1993-07-22
EP0553667A1 (de) 1993-08-04
JP4326534B2 (ja) 2009-09-09

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee