ATE218361T1 - Löslicher ldl-rezeptor, seine herstellung und verwendung - Google Patents

Löslicher ldl-rezeptor, seine herstellung und verwendung

Info

Publication number
ATE218361T1
ATE218361T1 AT93100587T AT93100587T ATE218361T1 AT E218361 T1 ATE218361 T1 AT E218361T1 AT 93100587 T AT93100587 T AT 93100587T AT 93100587 T AT93100587 T AT 93100587T AT E218361 T1 ATE218361 T1 AT E218361T1
Authority
AT
Austria
Prior art keywords
ldl receptor
production
soluble ldl
soluble
receptor protein
Prior art date
Application number
AT93100587T
Other languages
English (en)
Inventor
Menachem Rubinstein
Daniela Novick
Nathan Tal
Dina G Fischer
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL100696A external-priority patent/IL100696A0/xx
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Application granted granted Critical
Publication of ATE218361T1 publication Critical patent/ATE218361T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Sewing Machines And Sewing (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT93100587T 1992-01-19 1993-01-15 Löslicher ldl-rezeptor, seine herstellung und verwendung ATE218361T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL100696A IL100696A0 (en) 1992-01-19 1992-01-19 Antiviral protein and its preparation
IL10291592A IL102915A (en) 1992-01-19 1992-08-23 Soluble ldl receptor and its preparation

Publications (1)

Publication Number Publication Date
ATE218361T1 true ATE218361T1 (de) 2002-06-15

Family

ID=26322379

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93100587T ATE218361T1 (de) 1992-01-19 1993-01-15 Löslicher ldl-rezeptor, seine herstellung und verwendung

Country Status (10)

Country Link
EP (1) EP0553667B1 (de)
JP (2) JP3784078B2 (de)
AT (1) ATE218361T1 (de)
AU (1) AU663751B2 (de)
CA (1) CA2087494C (de)
DE (1) DE69331977T2 (de)
DK (1) DK0553667T3 (de)
ES (1) ES2177531T3 (de)
IL (1) IL102915A (de)
PT (1) PT553667E (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999038524A2 (en) * 1998-01-29 1999-08-05 Patrick Thomas Prendergast Therapeutic administration of low density lipoprotein receptor for viral infections and immune regulation
CN103897063B (zh) 2007-06-01 2017-04-12 马里兰大学巴尔的摩分校 免疫球蛋白恒定区Fc受体结合剂
IL188628A0 (en) * 2008-01-07 2008-12-29 Yeda Res & Dev Use of soluble ldl-r for viral hepatitis
EP3543257A1 (de) 2010-07-28 2019-09-25 Gliknik Inc. Fusionsproteine aus natürlichen menschlichen proteinfragmenten zur herstellung geordnet multimerisierter immunoglobulin-fc-zusammensetzungen
US20140370012A1 (en) * 2012-01-27 2014-12-18 Gliknik Inc. Fusion proteins comprising igg2 hinge domains
SI3325011T1 (sl) 2015-07-24 2021-02-26 Gliknik Inc. Fuzijski proteini humanih proteinskih fragmentov za tvorbo pravilnih multimeriziranih imunoglobulin FC sestavkov s povečanim vezanjem komplementa
CA3026420A1 (en) 2016-06-07 2017-12-14 Gliknik Inc. Cysteine-optimized stradomers
EP3551647A4 (de) 2016-12-09 2021-01-13 Gliknik Inc. Herstellungsoptimierung von gl-2045, einem multimerisierenden stradomer
IL266988B2 (en) 2016-12-09 2024-11-01 Gliknik Inc Methods of treating inflammatory disorders with multivalent fc compounds
US20260053948A1 (en) * 2022-09-15 2026-02-26 Yeda Research And Development Co. Ltd. Compositions and methods for virotherapy
CN120548322A (zh) * 2022-12-08 2025-08-26 美国杰特贝林生物制品有限公司 可解离的包膜结合蛋白及其用途
EP4467563A1 (de) * 2023-05-23 2024-11-27 JLP Health GmbH Von ldlr abgeleitete polypeptide für antivirale anwendungen
EP4688822A1 (de) * 2023-05-23 2026-02-11 JLP Health GmbH Von ldlr abgeleitete polypeptide für antivirale anwendungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4614651A (en) * 1981-07-12 1986-09-30 Damon Biotech, Inc. Interferon epsilon
US4454115A (en) * 1981-10-23 1984-06-12 Wisconsin Alumni Research Foundation Method of reducing the level of low density lipoproteins in the serum of a patient
CA2055122A1 (en) * 1990-11-13 1992-05-14 Robert I. Grove Methods for stimulating ldl uptake and ldl receptor expression

Also Published As

Publication number Publication date
IL102915A (en) 2005-12-18
CA2087494A1 (en) 1993-07-20
PT553667E (pt) 2002-10-31
AU3188993A (en) 1993-07-22
JP3784078B2 (ja) 2006-06-07
EP0553667A1 (de) 1993-08-04
DK0553667T3 (da) 2002-09-16
IL102915A0 (en) 1993-01-31
JPH06220099A (ja) 1994-08-09
DE69331977T2 (de) 2002-09-19
ES2177531T3 (es) 2002-12-16
AU663751B2 (en) 1995-10-19
CA2087494C (en) 2008-10-07
JP2006136341A (ja) 2006-06-01
EP0553667B1 (de) 2002-06-05
JP4326534B2 (ja) 2009-09-09
DE69331977D1 (de) 2002-07-11

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee