ES2177531T3 - Receptor de lipoproteinas de baja densidad (ldl), su produccion y su utilizacion. - Google Patents

Receptor de lipoproteinas de baja densidad (ldl), su produccion y su utilizacion.

Info

Publication number
ES2177531T3
ES2177531T3 ES93100587T ES93100587T ES2177531T3 ES 2177531 T3 ES2177531 T3 ES 2177531T3 ES 93100587 T ES93100587 T ES 93100587T ES 93100587 T ES93100587 T ES 93100587T ES 2177531 T3 ES2177531 T3 ES 2177531T3
Authority
ES
Spain
Prior art keywords
ldl
production
low density
density lipoprotein
lipoprotein receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93100587T
Other languages
English (en)
Inventor
Menachem Rubinstein
Daniela Novick
Nathan Tal
Dina G Fischer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL100696A external-priority patent/IL100696A0/xx
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Application granted granted Critical
Publication of ES2177531T3 publication Critical patent/ES2177531T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Sewing Machines And Sewing (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

SE DESCRIBE UN RECEPTOR PROTEINA LDL SOLUBLE. PUEDE SER AISLADO A PARTIR DE CELULAS QUE HAN SIDO TRATADAS CON UN INTERFERON, O PRODUCIDAS MEDIANTE TECNICAS RECOMBINANTES. EL RECEPTOR PROTEINA LDL SOLUBLE ES UTILIZABLE EN LA PROTECCION DE MAMIFEROS CONTRA INFECCIONES VIRALES.
ES93100587T 1992-01-19 1993-01-15 Receptor de lipoproteinas de baja densidad (ldl), su produccion y su utilizacion. Expired - Lifetime ES2177531T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL100696A IL100696A0 (en) 1992-01-19 1992-01-19 Antiviral protein and its preparation
IL10291592A IL102915A (en) 1992-01-19 1992-08-23 Soluble ldl receptor and its preparation

Publications (1)

Publication Number Publication Date
ES2177531T3 true ES2177531T3 (es) 2002-12-16

Family

ID=26322379

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93100587T Expired - Lifetime ES2177531T3 (es) 1992-01-19 1993-01-15 Receptor de lipoproteinas de baja densidad (ldl), su produccion y su utilizacion.

Country Status (10)

Country Link
EP (1) EP0553667B1 (es)
JP (2) JP3784078B2 (es)
AT (1) ATE218361T1 (es)
AU (1) AU663751B2 (es)
CA (1) CA2087494C (es)
DE (1) DE69331977T2 (es)
DK (1) DK0553667T3 (es)
ES (1) ES2177531T3 (es)
IL (1) IL102915A (es)
PT (1) PT553667E (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999038524A2 (en) * 1998-01-29 1999-08-05 Patrick Thomas Prendergast Therapeutic administration of low density lipoprotein receptor for viral infections and immune regulation
CN101835802B (zh) 2007-06-01 2014-04-09 马里兰大学巴尔的摩分校 免疫球蛋白恒定区Fc受体结合剂
IL188628A0 (en) 2008-01-07 2008-12-29 Yeda Res & Dev Use of soluble ldl-r for viral hepatitis
WO2012016073A2 (en) 2010-07-28 2012-02-02 Gliknik Inc. Fusion proteins of natural human protein fragments to create orderly multimerized immunoglobulin fc compositions
US20140370012A1 (en) * 2012-01-27 2014-12-18 Gliknik Inc. Fusion proteins comprising igg2 hinge domains
LT3325011T (lt) 2015-07-24 2021-01-25 Gliknik Inc. Iš žmogaus baltymo fragmentų sulieti baltymai, siekiant sukurti tvarkingai multimerizuoto imunoglobulino fc kompozicijas su padidintu komplemento surišimu
WO2017214321A1 (en) 2016-06-07 2017-12-14 Gliknik Inc. Cysteine-optimized stradomers
CN110177802A (zh) 2016-12-09 2019-08-27 格利克尼克股份有限公司 多聚化stradomer GL-2045的制造优化
CA3043251A1 (en) 2016-12-09 2018-06-14 Gliknik Inc. Methods of treating inflammatory disorders with multivalent fc compounds
CA3266482A1 (en) * 2022-09-15 2024-03-21 Yeda Research And Development Co. Ltd. Virotherapy Compositions and Methods
WO2024121798A1 (en) * 2022-12-08 2024-06-13 Csl Behring Llc Dissociable envelope binding proteins and uses thereof
EP4688822A1 (en) * 2023-05-23 2026-02-11 JLP Health GmbH Ldlr derived polypeptides for anti-viral uses
EP4467563A1 (en) * 2023-05-23 2024-11-27 JLP Health GmbH Ldlr derived polypeptides for anti-viral uses

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4614651A (en) * 1981-07-12 1986-09-30 Damon Biotech, Inc. Interferon epsilon
US4454115A (en) * 1981-10-23 1984-06-12 Wisconsin Alumni Research Foundation Method of reducing the level of low density lipoproteins in the serum of a patient
CA2055122A1 (en) * 1990-11-13 1992-05-14 Robert I. Grove Methods for stimulating ldl uptake and ldl receptor expression

Also Published As

Publication number Publication date
AU663751B2 (en) 1995-10-19
DE69331977T2 (de) 2002-09-19
IL102915A0 (en) 1993-01-31
DE69331977D1 (de) 2002-07-11
JP3784078B2 (ja) 2006-06-07
ATE218361T1 (de) 2002-06-15
CA2087494C (en) 2008-10-07
AU3188993A (en) 1993-07-22
DK0553667T3 (da) 2002-09-16
IL102915A (en) 2005-12-18
CA2087494A1 (en) 1993-07-20
EP0553667A1 (en) 1993-08-04
JPH06220099A (ja) 1994-08-09
JP4326534B2 (ja) 2009-09-09
JP2006136341A (ja) 2006-06-01
PT553667E (pt) 2002-10-31
EP0553667B1 (en) 2002-06-05

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