ATE218535T1 - Aminotetralinderivate, deren zusammensetzungen sowie deren verwendung - Google Patents

Aminotetralinderivate, deren zusammensetzungen sowie deren verwendung

Info

Publication number
ATE218535T1
ATE218535T1 AT97905261T AT97905261T ATE218535T1 AT E218535 T1 ATE218535 T1 AT E218535T1 AT 97905261 T AT97905261 T AT 97905261T AT 97905261 T AT97905261 T AT 97905261T AT E218535 T1 ATE218535 T1 AT E218535T1
Authority
AT
Austria
Prior art keywords
hydrogen
compositions
aminotetralin derivatives
alkoxy
halogen
Prior art date
Application number
AT97905261T
Other languages
English (en)
Inventor
Edward John Warawa
Bernard Migler
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE218535T1 publication Critical patent/ATE218535T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Psychology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT97905261T 1996-03-01 1997-02-25 Aminotetralinderivate, deren zusammensetzungen sowie deren verwendung ATE218535T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1264096P 1996-03-01 1996-03-01
PCT/GB1997/000516 WO1997031887A1 (en) 1996-03-01 1997-02-25 Aminotetralin derivatives and compositions and method of use thereof

Publications (1)

Publication Number Publication Date
ATE218535T1 true ATE218535T1 (de) 2002-06-15

Family

ID=21755962

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97905261T ATE218535T1 (de) 1996-03-01 1997-02-25 Aminotetralinderivate, deren zusammensetzungen sowie deren verwendung

Country Status (14)

Country Link
US (1) US5807897A (de)
EP (1) EP0883599B1 (de)
JP (1) JP4083221B2 (de)
KR (1) KR19990087369A (de)
CN (1) CN1212682A (de)
AT (1) ATE218535T1 (de)
AU (1) AU733264B2 (de)
DE (1) DE69713067T2 (de)
IL (1) IL125907A0 (de)
NO (1) NO983990D0 (de)
NZ (1) NZ330974A (de)
TW (1) TW409113B (de)
WO (1) WO1997031887A1 (de)
ZA (1) ZA971670B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726736D0 (en) * 1997-12-18 1998-02-18 Zeneca Ltd Chemical compounds
AU1874500A (en) * 1998-12-24 2000-07-31 Astrazeneca Ab 1,4-diazacycloheptane derivatives useful in the treatment of neurological disorders
GB9914015D0 (en) * 1999-06-17 1999-08-18 Zeneca Ltd Chemical compounds
GB9914025D0 (en) * 1999-06-17 1999-08-18 Zeneca Ltd Chemical compounds
GB9914024D0 (en) * 1999-06-17 1999-08-18 Zeneca Ltd Chemical compounds
PL1658277T3 (pl) * 2003-08-18 2012-10-31 H Lundbeck As Sól bursztynianowa i malonianowa trans-4-((1R,3S)-6-chloro-3-fenyloindan-1-ylo)-1,2,2-tri-metylopiperazyny i zastosowanie jako lek
TWI453198B (zh) * 2005-02-16 2014-09-21 Lundbeck & Co As H 製造反式-1-((1r,3s)-6-氯基-3-苯基茚滿-1-基) -3 , 3 -二甲基六氫吡與其鹽類之方法及製造4-((1r , 3s）-6 -氯基-3-苯基茚滿-1-基 )-1,2,2-三甲基六氫吡與其鹽類之方法
TWI376373B (en) * 2005-02-16 2012-11-11 Lundbeck & Co As H Crystalline base of a pharmaceutical compound
WO2009135495A1 (en) * 2008-05-07 2009-11-12 H. Lundbeck A/S Method for treating cognitive deficits
BRPI0919165A2 (pt) * 2008-10-03 2015-12-08 Lundbeck & Co As H composição farmacêutica,e, uso de um composto
BR112023025599A2 (pt) 2021-06-08 2024-02-20 Entheogenix Biosciences Inc Ativadores de dimetoxifenilalquilamina de receptores de serotonina.
JP2024547131A (ja) 2021-12-27 2024-12-26 エーティーエーアイ セラピューティクス，インコーポレイテッド セロトニン受容体のアミノテトラリン活性化剤
EP4704822A1 (de) 2023-05-01 2026-03-11 ATAI Therapeutics, Inc. Zusammensetzungen und verfahren zur behandlung von erkrankungen und störungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320148A (en) * 1980-11-24 1982-03-16 Smithkline Corporation 2-Aminotetralin compounds, pharmaceutical compositions and method of producing central alpha1 agonist activity
US5225596A (en) * 1989-01-09 1993-07-06 The Upjohn Company Halo substituted aminotetralins
SE8904127D0 (sv) * 1989-12-07 1989-12-07 Astra Ab New biocyclic amino-substituted compounds
EP0450238A1 (de) * 1990-03-30 1991-10-09 Merrell Dow Pharmaceuticals Inc. Verbindungen für die Behandlung von Migräne

Also Published As

Publication number Publication date
US5807897A (en) 1998-09-15
IL125907A0 (en) 1999-04-11
JP4083221B2 (ja) 2008-04-30
JP2000506137A (ja) 2000-05-23
NZ330974A (en) 2000-05-26
EP0883599B1 (de) 2002-06-05
KR19990087369A (ko) 1999-12-27
AU1887997A (en) 1997-09-16
WO1997031887A1 (en) 1997-09-04
CN1212682A (zh) 1999-03-31
AU733264B2 (en) 2001-05-10
NO983990L (no) 1998-08-31
EP0883599A1 (de) 1998-12-16
DE69713067T2 (de) 2002-12-19
TW409113B (en) 2000-10-21
ZA971670B (en) 1997-09-01
NO983990D0 (no) 1998-08-31
DE69713067D1 (de) 2002-07-11

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