ATE218560T1 - Wasserlösliche ähnliche verbindungen und medicament-vorstufe von paclitaxel - Google Patents

Wasserlösliche ähnliche verbindungen und medicament-vorstufe von paclitaxel

Info

Publication number
ATE218560T1
ATE218560T1 AT98940677T AT98940677T ATE218560T1 AT E218560 T1 ATE218560 T1 AT E218560T1 AT 98940677 T AT98940677 T AT 98940677T AT 98940677 T AT98940677 T AT 98940677T AT E218560 T1 ATE218560 T1 AT E218560T1
Authority
AT
Austria
Prior art keywords
paclitaxel
products
water
similar compounds
soluble
Prior art date
Application number
AT98940677T
Other languages
English (en)
Inventor
Peter Hermanus Gera Wiegerinck
Duncan Sperling
Lesly Braamer
Eric Wilhelmus Petrus Damen
Johan Wilhelm Scheeren
Vos Dick De
Original Assignee
Pharmachemie Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmachemie Bv filed Critical Pharmachemie Bv
Application granted granted Critical
Publication of ATE218560T1 publication Critical patent/ATE218560T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AT98940677T 1998-08-21 1998-08-21 Wasserlösliche ähnliche verbindungen und medicament-vorstufe von paclitaxel ATE218560T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/NL1998/000473 WO2000010988A1 (en) 1998-08-21 1998-08-21 Water soluble analogs and prodrugs of paclitaxel

Publications (1)

Publication Number Publication Date
ATE218560T1 true ATE218560T1 (de) 2002-06-15

Family

ID=19866454

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98940677T ATE218560T1 (de) 1998-08-21 1998-08-21 Wasserlösliche ähnliche verbindungen und medicament-vorstufe von paclitaxel

Country Status (11)

Country Link
US (1) US6344571B2 (de)
EP (1) EP1105379B1 (de)
JP (1) JP2002523407A (de)
AT (1) ATE218560T1 (de)
AU (1) AU8889998A (de)
CA (1) CA2341234A1 (de)
DE (1) DE69805860T2 (de)
DK (1) DK1105379T3 (de)
ES (1) ES2179526T3 (de)
PT (1) PT1105379E (de)
WO (1) WO2000010988A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6414015B1 (en) 2000-01-28 2002-07-02 Utah State University Laulimalide microtubule stabilizing agents
DE60131537T2 (de) 2000-06-22 2008-10-23 Nitromed, Inc., Lexington Nitrosierte und nitrosylierte taxane, zubereitungen und methoden der verwendung
US7212534B2 (en) 2001-07-23 2007-05-01 Broadcom Corporation Flow based congestion control
ITPD20020271A1 (it) 2002-10-18 2004-04-19 Fidia Farmaceutici Composti chimico-farmaceutici costituiti da derivati dei taxani legati covalentemente all'acido ialuronico o ai suoi derivati.
US20050148534A1 (en) * 2003-09-22 2005-07-07 Castellino Angelo J. Small molecule compositions and methods for increasing drug efficiency using compositions thereof
MX2007010394A (es) * 2005-02-24 2008-02-19 Elan Pharma Int Ltd Formulaciones nanoparticuladas de docetaxel y analogos del mismo.
TW200731991A (en) * 2005-12-20 2007-09-01 Sonus Pharma Inc Lipophilic di(anticancer drug) compounds, compositions and related methods
CN101029034B (zh) * 2007-03-30 2010-05-26 浙江大学 多烯紫杉醇水溶性衍生物及制备方法和用途
CN106800542A (zh) * 2016-12-31 2017-06-06 辰欣药业股份有限公司 一种亲水性紫杉醇类化合物及其制备方法
CN108424405A (zh) * 2018-03-06 2018-08-21 华东师范大学 伏立诺他和紫杉醇的共前药及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
WO1994005282A1 (en) * 1992-09-04 1994-03-17 The Scripps Research Institute Water soluble taxol derivatives

Also Published As

Publication number Publication date
CA2341234A1 (en) 2000-03-02
AU8889998A (en) 2000-03-14
ES2179526T3 (es) 2003-01-16
US6344571B2 (en) 2002-02-05
US20010018531A1 (en) 2001-08-30
PT1105379E (pt) 2002-10-31
JP2002523407A (ja) 2002-07-30
DK1105379T3 (da) 2002-08-19
EP1105379A1 (de) 2001-06-13
DE69805860D1 (de) 2002-07-11
WO2000010988A1 (en) 2000-03-02
EP1105379B1 (de) 2002-06-05
DE69805860T2 (de) 2003-01-02
WO2000010988A8 (en) 2000-06-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee