ATE218568T1 - Hetero-biaryl-pyridochinazolinonderivate als antikrebsmittel - Google Patents

Hetero-biaryl-pyridochinazolinonderivate als antikrebsmittel

Info

Publication number: ATE218568T1
Authority: AT; Austria
Prior art keywords: pyridoquinazolinone; ch2ch2nh2; group; alkyl; biaryl
Prior art date: 1996-11-26

Application number

AT97948622T

Other languages

English (en)

Inventor

Michael Peter Trova

Nan Zhang

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-11-26

Filing date

1997-11-24

Publication date

2002-06-15

1997-11-24 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

2002-06-15 Application granted granted Critical

2002-06-15 Publication of ATE218568T1 publication Critical patent/ATE218568T1/de

Links

239000002246 antineoplastic agent Substances 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 4
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
-1 -CO2R4 Chemical group 0.000 abstract 1
QZGXKHLZLRKTOV-UHFFFAOYSA-N 1h-pyrido[2,3-h]quinazolin-2-one Chemical group N1=CC=CC2=C(NC(=O)N=C3)C3=CC=C21 QZGXKHLZLRKTOV-UHFFFAOYSA-N 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
229940034982 antineoplastic agent Drugs 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
239000011593 sulfur Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Oncology (AREA)
Hematology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT97948622T 1996-11-26 1997-11-24 Hetero-biaryl-pyridochinazolinonderivate als antikrebsmittel ATE218568T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US75584596A	1996-11-26	1996-11-26
PCT/US1997/022502 WO1998023617A1 (en)	1996-11-26	1997-11-24	Hetero-biaryl-pyridoquinazolinone derivatives as anti-cancer agents

Publications (1)

Publication Number	Publication Date
ATE218568T1 true ATE218568T1 (de)	2002-06-15

Family

ID=25040889

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97948622T ATE218568T1 (de)	1996-11-26	1997-11-24	Hetero-biaryl-pyridochinazolinonderivate als antikrebsmittel

Country Status (10)

Country	Link
EP (1)	EP0944628B1 (de)
JP (1)	JP2001507341A (de)
AT (1)	ATE218568T1 (de)
AU (1)	AU5465198A (de)
CA (1)	CA2272915A1 (de)
DE (1)	DE69713139T2 (de)
DK (1)	DK0944628T3 (de)
ES (1)	ES2176800T3 (de)
PT (1)	PT944628E (de)
WO (1)	WO1998023617A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR101315628B1 (ko) *	2008-08-12	2013-10-08	닛뽕소다 가부시키가이샤	함질소 헤테로고리 유도체 및 농원예용 살균제
EP2484672B1 (de)	2009-09-28	2015-07-15	Nippon Soda Co., Ltd.	Stickstoffhaltige heterocyclische verbindung und salz daraus sowie herbizid für landwirtschaft und gartenbau
CA3066009A1 (en) *	2017-06-01	2018-12-06	Oncostellae, S.L.	Pyridoquinazoline derivatives useful as protein kinase inhibitors
ES2692433A1 (es) *	2017-06-01	2018-12-03	Oncostellae, S.L.	Derivados de ácidos carboxílicos como inhibidores de proteinas quinasa
JP2023542930A (ja)	2020-09-23	2023-10-12	セントジュードチルドレンズリサーチホスピタルインコーポレイテッド	セレブロンタンパク質のモジュレータとしての置換ｎ－（２－（２，６－ジオキソピペリジン－３－イル）－１，３－ジオキソイソインドリン－５－イル）アリールスルホンアミド類似体

1997
- 1997-11-24 ES ES97948622T patent/ES2176800T3/es not_active Expired - Lifetime
- 1997-11-24 DK DK97948622T patent/DK0944628T3/da active
- 1997-11-24 JP JP52492998A patent/JP2001507341A/ja active Pending
- 1997-11-24 CA CA002272915A patent/CA2272915A1/en not_active Abandoned
- 1997-11-24 PT PT97948622T patent/PT944628E/pt unknown
- 1997-11-24 DE DE69713139T patent/DE69713139T2/de not_active Expired - Fee Related
- 1997-11-24 AU AU54651/98A patent/AU5465198A/en not_active Abandoned
- 1997-11-24 AT AT97948622T patent/ATE218568T1/de not_active IP Right Cessation
- 1997-11-24 EP EP97948622A patent/EP0944628B1/de not_active Expired - Lifetime
- 1997-11-24 WO PCT/US1997/022502 patent/WO1998023617A1/en not_active Ceased

Also Published As

Publication number	Publication date
DE69713139T2 (de)	2002-12-19
DK0944628T3 (da)	2002-08-26
HK1021373A1 (en)	2000-06-09
CA2272915A1 (en)	1998-06-04
DE69713139D1 (de)	2002-07-11
EP0944628A1 (de)	1999-09-29
AU5465198A (en)	1998-06-22
EP0944628B1 (de)	2002-06-05
ES2176800T3 (es)	2002-12-01
JP2001507341A (ja)	2001-06-05
PT944628E (pt)	2002-09-30
WO1998023617A1 (en)	1998-06-04

Legal Events

Date	Code	Title
2002-10-15	UEP	Publication of translation of european patent specification
2003-11-15	EEFA	Change of the company name
2005-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
CA2178219A1 (en)	1995-07-06	Substituted morpholine derivatives and their use as therapeutic agents
ATE206412T1 (de)	2001-10-15	Heterocyclische verbindungen als bradykinin antagonisten
ATE275134T1 (de)	2004-09-15	4-oxo-1,4-dihydro-3-chinolincarboxamide als antivirale mittel
MY106980A (en)	1995-08-30	Heterocyclic compounds
ATE114670T1 (de)	1994-12-15	Phenylamidinderivate als plättchenaggregationsinhibitoren.
NO933452D0 (no)	1993-09-27	Et terapeutisk middel for parkinson's sykdom
NO944876L (no)	1995-06-22	Sammensetning for behandling av menstruelle symptomer
CS9003037A2 (en)	1991-11-12	Means for chemotherapy
IE792074L (en)	1980-04-30	Pyran- and thiopyran-fused heterocyclic compounds
FI862757A0 (fi)	1986-06-27	Pyridonkarbonsyraderivat och foerfarande foer framstaellning av dessa.
ATE277049T1 (de)	2004-10-15	Substituierte aminoalkylverbindungen
MA23639A1 (fr)	1996-04-01	Derives pyrrocarbazole, leur preparation, les compositions pharmaceutiques les contenant, leur utilisation dans le traitement des tumeurs malignes.
ATE218568T1 (de)	2002-06-15	Hetero-biaryl-pyridochinazolinonderivate als antikrebsmittel
FR2531711B1 (de)	1985-02-01
ES472591A1 (es)	1979-10-16	Procedimiento para la obtencion de derivados de 1-fenileta- nolamina
KR900004706A (ko)	1990-04-12	Lo/co 억제 벤즈옥사졸론
TW333525B (en)	1998-06-11	New perhydroisoindole derivatives, their preparation and the pharmaceutical compositions which contain them the invention relates to perhydroisoindole derivatives of general formula (I), and their salts when they exist advantageously as neurokinin A antagonists.
ATE85056T1 (de)	1993-02-15	Tetracyclische indolderivate.
DE69715241D1 (de)	2002-10-10	Biaryl-pyridochinazolinonderivate als antikrebsmittel
JO1047B1 (en)	1982-07-10	Vehicles
YU223290A (sh)	1992-12-21	Triazolil tioamid derivati